Task 54785815

Name	HuVeMOp_20240622190825179238_ORdGradInc_k_23-Pueyo_APDR-conf_865_2
Workunit	25795253
Created	26 Jun 2024, 4:45:55 UTC
Sent	26 Jun 2024, 6:59:02 UTC
Report deadline	29 Jun 2024, 16:35:02 UTC
Received	27 Jun 2024, 13:08:53 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	216581
Run time	1 hours 20 min 24 sec
CPU time	1 hours 4 min 10 sec
Validate state	Valid
Credit	58.90
Device peak FLOPS	5.02 GFLOPS
Application version	Human ventricular cell models optimization v0.02 windows_x86_64
Peak working set size	7.52 MB
Peak swap size	1.53 MB
Peak disk usage	0.28 MB
Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622190825179238_ORdGradInc_k_23-Pueyo_APDR-conf_865.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622190825179238_ORdGradInc_k_23-Pueyo_APDR-conf_865_2_r1162680156_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622190825179238_ORdGradInc_k_23-Pueyo_APDR-conf_865_2_r1162680156_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 155.454179
     * GNaL_b in INaL: 0.012447
     * Gto_b in Ito: 0.045069
     * PCa_b in ICaL: 0.000082
     * GKr_b in IKr: 0.032919
     * GKs_b in IKs: 0.001777
     * GK1_b in IK1: 0.217347
     * Gncx_b in INaCa_i: 0.000996
     * Pnak_b in INaK: 59.325701
     * GKb_b in IKb: 0.003714
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.086309
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9177800, states[0] = -95.322167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21014167, states[0] = 29.998696, states[40]= 0.027580
Saving checkpoint... 
Iteration: 30405125, states[0] = -95.450846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42049985, states[0] = 16.232778, states[40]= 0.005674
Saving checkpoint... 
Iteration: 54429367, states[0] = -95.448986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66462882, states[0] = -95.451079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78451529, states[0] = -95.448827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90399887, states[0] = -95.441174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101987743, states[0] = -95.450670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113822496, states[0] = -95.421334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125711678, states[0] = -95.351103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137501639, states[0] = 56.682178, states[40]= 0.025694
Saving checkpoint... 
Iteration: 149067366, states[0] = 9.604038, states[40]= 0.005110
Saving checkpoint... 
Iteration: 161216080, states[0] = -95.355030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173213293, states[0] = -95.352150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185088017, states[0] = 0.034343, states[40]= 0.004185
Saving checkpoint... 
Iteration: 197266706, states[0] = -95.394602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206948448, states[0] = -95.445671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219408888, states[0] = -95.440556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232847382, states[0] = -95.427866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245490546, states[0] = -95.449359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257695518, states[0] = -95.332649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270753743, states[0] = -95.386124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280526136, states[0] = 25.678118, states[40]= 0.009625
Saving checkpoint... 
Iteration: 293346767, states[0] = -95.427651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305512583, states[0] = 31.144770, states[40]= 0.034494
Saving checkpoint... 
Iteration: 318659717, states[0] = -76.096300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330926547, states[0] = -95.442970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343315441, states[0] = -95.417661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350571810, states[0] = 7.758947, states[40]= 0.004974
Saving checkpoint... 
Iteration: 362870923, states[0] = -95.433517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374970074, states[0] = -95.447653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387002657, states[0] = 50.751184, states[40]= 0.045556
Saving checkpoint... 
Iteration: 399195088, states[0] = -95.332100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411476890, states[0] = -95.448228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423867323, states[0] = -95.432708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435686984, states[0] = -95.321955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447859463, states[0] = -95.430872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460211976, states[0] = -95.350524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472521906, states[0] = 27.218383, states[40]= 0.012372
Saving checkpoint... 
Iteration: 484255111, states[0] = -95.387000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496684001, states[0] = -95.316689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506321233, states[0] = -95.419705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518563363, states[0] = 11.259694, states[40]= 0.005222
Saving checkpoint... 
Iteration: 528118520, states[0] = -23.734426, states[40]= 0.000784
Saving checkpoint... 
Iteration: 539847098, states[0] = -95.427682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551971185, states[0] = -95.447714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563804921, states[0] = -95.413518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575535313, states[0] = 22.255374, states[40]= 0.007007
Saving checkpoint... 
Iteration: 587729614, states[0] = -95.367245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599640452, states[0] = -45.692034, states[40]= 0.000055
Saving checkpoint... 
Iteration: 611353616, states[0] = -95.429385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623368951, states[0] = -95.433030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635183299, states[0] = -95.314992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647434981, states[0] = -95.443961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659092320, states[0] = -2.435139, states[40]= 0.003788
Saving checkpoint... 
Iteration: 671156925, states[0] = -70.146204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683530429, states[0] = 24.097542, states[40]= 0.008070
Saving checkpoint... 
Iteration: 695628005, states[0] = -32.530691, states[40]= 0.000354
Saving checkpoint... 
Iteration: 704611038, states[0] = -16.996061, states[40]= 0.001190
Saving checkpoint... 
Iteration: 713355673, states[0] = -95.429885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725518640, states[0] = 28.436379, states[40]= 0.016289
Saving checkpoint... 
Iteration: 737245065, states[0] = -95.379767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749262642, states[0] = -95.391868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761289967, states[0] = -95.406864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773186345, states[0] = -95.320920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785184828, states[0] = -95.318321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796989456, states[0] = -95.449135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809132891, states[0] = -37.341185, states[40]= 0.000186
Saving checkpoint... 
Iteration: 820893065, states[0] = -95.437766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832819241, states[0] = -95.418937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844964837, states[0] = -95.447084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857430751, states[0] = -95.443397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869448045, states[0] = -95.445404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878804258, states[0] = -95.413181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890500305, states[0] = -57.999462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902122873, states[0] = -27.714036, states[40]= 0.000593
Saving checkpoint... 
Iteration: 914258258, states[0] = -95.389015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926600269, states[0] = -7.886482, states[40]= 0.002684
Saving checkpoint... 
Iteration: 938409682, states[0] = -95.440468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950324966, states[0] = -95.420894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962115589, states[0] = -21.085318, states[40]= 0.000905
Saving checkpoint... 
Iteration: 973903403, states[0] = -95.439479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985928658, states[0] = -95.443106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998041002, states[0] = 20.062053, states[40]= 0.006267
Saving checkpoint... 
Iteration: 1010353717, states[0] = -95.429330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022214263, states[0] = -95.352729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034212470, states[0] = -95.350912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043849586, states[0] = -95.428248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056442201, states[0] = -95.444722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068905266, states[0] = -95.439757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081379996, states[0] = -95.435257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093964540, states[0] = -95.447006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106459080, states[0] = -95.446485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123870988, states[0] = -95.433374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136230374, states[0] = -95.367796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148919503, states[0] = -95.441852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161293946, states[0] = -95.408640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173967267, states[0] = -95.447239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186112371, states[0] = -18.190165, states[40]= 0.001086
Saving checkpoint... 
Iteration: 1195432064, states[0] = -95.443492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207711163, states[0] = -95.349536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220325551, states[0] = -95.421036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232760917, states[0] = -95.390675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245451158, states[0] = -95.445658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247684959, states[0] = -95.318473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260020929, states[0] = 27.577212, states[40]= 0.013317
Saving checkpoint... 
Iteration: 1272924090, states[0] = -95.442451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281841812, states[0] = -95.426057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294098022, states[0] = -6.217008, states[40]= 0.003039
Saving checkpoint... 
Iteration: 1303307766, states[0] = -95.414517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315611768, states[0] = -17.649394, states[40]= 0.001130
Saving checkpoint... 
Iteration: 1324867840, states[0] = -95.432640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336796632, states[0] = -95.409817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348714183, states[0] = -95.352582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360616584, states[0] = -21.982907, states[40]= 0.000862
Saving checkpoint... 
Iteration: 1373499600, states[0] = -95.449736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385928075, states[0] = -95.442950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389915743, states[0] = -95.441271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401555781, states[0] = 14.277518, states[40]= 0.005440
Saving checkpoint... 
Iteration: 1413677591, states[0] = -95.273277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415077479, states[0] = 5.261220, states[40]= 0.004772
Saving checkpoint... 
Iteration: 1427129115, states[0] = -33.598598, states[40]= 0.000309
Saving checkpoint... 
Iteration: 1439166490, states[0] = -91.229837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451175007, states[0] = -95.190786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463124193, states[0] = -28.937261, states[40]= 0.000529
Saving checkpoint... 
Iteration: 1475441130, states[0] = -95.444515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487441262, states[0] = -95.444527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499615201, states[0] = -20.735533, states[40]= 0.000923
Saving checkpoint... 
Iteration: 1512082680, states[0] = -6.243990, states[40]= 0.003406
Saving checkpoint... 
Iteration: 1524598863, states[0] = -95.624430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536463375, states[0] = -95.515373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548441903, states[0] = -88.653203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560945629, states[0] = 14.253222, states[40]= 0.006559
Saving checkpoint... 
Iteration: 1573133926, states[0] = -95.604077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585297095, states[0] = -22.578655, states[40]= 0.000871
Saving checkpoint... 
Iteration: 1597216083, states[0] = 28.760302, states[40]= 0.022719
Saving checkpoint... 
Iteration: 1609591994, states[0] = -17.589381, states[40]= 0.001281
Saving checkpoint... 
Iteration: 1621901921, states[0] = -27.744868, states[40]= 0.000588
Saving checkpoint... 
Iteration: 1633931331, states[0] = -66.743759, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1643869286, states[0] = -95.538275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655678832, states[0] = -95.634473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668050513, states[0] = 11.552790, states[40]= 0.006197
Saving checkpoint... 
Iteration: 1680025137, states[0] = 24.141937, states[40]= 0.011243
Saving checkpoint... 
Iteration: 1692024437, states[0] = 24.479273, states[40]= 0.011658
Saving checkpoint... 
Iteration: 1704163249, states[0] = -95.528816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716215177, states[0] = -95.593151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728395935, states[0] = -21.739293, states[40]= 0.000925
Saving checkpoint... 
Iteration: 1740252546, states[0] = -95.620990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752201403, states[0] = -95.579658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764402343, states[0] = -28.295741, states[40]= 0.000559
Saving checkpoint... 
Iteration: 1776859434, states[0] = -95.624998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788426023, states[0] = -57.732902, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1800461033, states[0] = -95.485058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812801761, states[0] = -95.435976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821689080, states[0] = -95.343305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833104397, states[0] = -13.083499, states[40]= 0.001714
Saving checkpoint... 
Iteration: 1845283008, states[0] = -95.413617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857376608, states[0] = -95.441780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869828510, states[0] = -95.427114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882054648, states[0] = 14.560855, states[40]= 0.005484
Saving checkpoint... 
Iteration: 1894112173, states[0] = -18.393834, states[40]= 0.001072
Saving checkpoint... 
Iteration: 1906197385, states[0] = -95.336358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918548996, states[0] = 16.885067, states[40]= 0.005707
Saving checkpoint... 
Iteration: 1930477287, states[0] = -95.448927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942491567, states[0] = -95.449755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954782611, states[0] = -95.403486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966817864, states[0] = -95.418567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975485078, states[0] = -95.448838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984397048, states[0] = -95.438432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993266312, states[0] = -95.394044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005213062, states[0] = -95.351430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017087149, states[0] = 0.509512, states[40]= 0.004252
Saving checkpoint... 
Iteration: 2029170960, states[0] = -94.627389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041238332, states[0] = -95.374295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053213013, states[0] = -95.351272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065600863, states[0] = -8.347624, states[40]= 0.002586
Saving checkpoint... 
Iteration: 2078309848, states[0] = -95.415179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090634118, states[0] = -38.607434, states[40]= 0.000155
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.325480
 - CaMKt in component CaMK (millimolar): 0.005401
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.799246
 - nass in component intracellular_ions (millimolar): 6.799302
 - ki in component intracellular_ions (millimolar): 145.204947
 - kss in component intracellular_ions (millimolar): 145.204924
 - cansr in component intracellular_ions (millimolar): 1.209153
 - cajsr in component intracellular_ions (millimolar): 1.171964
 - cai in component intracellular_ions (millimolar): 0.000070
 - m in component INa (dimensionless): 0.003467
 - hf in component INa (dimensionless): 0.887159
 - hs in component INa (dimensionless): 0.887157
 - j in component INa (dimensionless): 0.887141
 - hsp in component INa (dimensionless): 0.739474
 - jp in component INa (dimensionless): 0.887130
 - mL in component INaL (dimensionless): 0.000046
 - hL in component INaL (dimensionless): 0.719387
 - hLp in component INaL (dimensionless): 0.460041
 - a in component Ito (dimensionless): 0.000606
 - iF in component Ito (dimensionless): 0.999879
 - iS in component Ito (dimensionless): 0.612325
 - ap in component Ito (dimensionless): 0.000309
 - iFp in component Ito (dimensionless): 0.999879
 - iSp in component Ito (dimensionless): 0.684362
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.913547
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999794
 - jca in component ICaL (dimensionless): 0.999967
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001259
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.369488
 - xs1 in component IKs (dimensionless): 0.276302
 - xs2 in component IKs (dimensionless): 0.000084
 - xk1 in component IK1 (dimensionless): 0.997223
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:23:28 (31776): called boinc_finish(0)

</stderr_txt>
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