𝕏

Task 54785705

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_64_0
Workunit 26012715
Created 26 Jun 2024, 4:45:50 UTC
Sent 26 Jun 2024, 6:59:02 UTC
Report deadline 29 Jun 2024, 16:35:02 UTC
Received 27 Jun 2024, 13:08:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216581
Run time 1 hours 20 min 36 sec
CPU time 1 hours 4 min 14 sec
Validate state Valid
Credit 60.44
Device peak FLOPS 5.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.50 MB
Peak swap size 1.53 MB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_64.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_64_0_r379751094_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_64_0_r379751094_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.596368
     * GNaL_b in INaL: 0.009270
     * Gto_b in Ito: 0.084639
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033477
     * GKs_b in IKs: 0.001854
     * GK1_b in IK1: 0.160117
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 67.294181
     * GKb_b in IKb: 0.003898
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052621
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9158975, states[0] = -86.377154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21317144, states[0] = -95.100165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33248216, states[0] = -95.020146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45067824, states[0] = 6.122300, states[40]= 0.004748
Saving checkpoint... 
Iteration: 57015475, states[0] = 22.892399, states[40]= 0.016630
Saving checkpoint... 
Iteration: 69058913, states[0] = 10.064529, states[40]= 0.004864
Saving checkpoint... 
Iteration: 80845098, states[0] = -95.075231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92506092, states[0] = 26.484372, states[40]= 0.126364
Saving checkpoint... 
Iteration: 104525965, states[0] = 21.153212, states[40]= 0.006649
Saving checkpoint... 
Iteration: 116257093, states[0] = -95.001530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128118465, states[0] = -30.512198, states[40]= 0.000484
Saving checkpoint... 
Iteration: 137147512, states[0] = -61.654949, states[40]= 0.000005
Saving checkpoint... 
Iteration: 148996205, states[0] = -95.107661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159065065, states[0] = 7.752147, states[40]= 0.004796
Saving checkpoint... 
Iteration: 170908940, states[0] = -95.091520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183263796, states[0] = -95.006919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195299999, states[0] = -95.040314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207402697, states[0] = -95.089453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218784283, states[0] = -95.027137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230566065, states[0] = 7.343081, states[40]= 0.004781
Saving checkpoint... 
Iteration: 242487198, states[0] = -95.105583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254533675, states[0] = 19.127300, states[40]= 0.005525
Saving checkpoint... 
Iteration: 266282530, states[0] = -95.025419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278155224, states[0] = -72.101980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290245354, states[0] = -94.983973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302033278, states[0] = 19.245647, states[40]= 0.005560
Saving checkpoint... 
Iteration: 314244629, states[0] = -94.982974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326320681, states[0] = -95.054238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336114239, states[0] = -26.548205, states[40]= 0.000684
Saving checkpoint... 
Iteration: 348556713, states[0] = 11.114748, states[40]= 0.004873
Saving checkpoint... 
Iteration: 361818660, states[0] = -95.052944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374817517, states[0] = -95.052207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387137795, states[0] = -49.963149, states[40]= 0.000032
Saving checkpoint... 
Iteration: 400116881, states[0] = -28.954207, states[40]= 0.000563
Saving checkpoint... 
Iteration: 409809399, states[0] = -95.046767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422320565, states[0] = -95.054097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434769492, states[0] = -95.012518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447895299, states[0] = -95.086969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460289509, states[0] = -95.031416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472743846, states[0] = -94.981802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480062671, states[0] = 8.758800, states[40]= 0.004826
Saving checkpoint... 
Iteration: 492024761, states[0] = 21.465922, states[40]= 0.006985
Saving checkpoint... 
Iteration: 504489651, states[0] = -95.105650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516897762, states[0] = -95.087655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528955065, states[0] = -95.100616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541012023, states[0] = 23.435276, states[40]= 0.032787
Saving checkpoint... 
Iteration: 553469164, states[0] = -95.102848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565674763, states[0] = -94.428807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577718498, states[0] = -94.942731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590253214, states[0] = -94.993879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602431126, states[0] = -95.095988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613987457, states[0] = -95.105308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626509038, states[0] = 24.137135, states[40]= 0.065569
Saving checkpoint... 
Iteration: 636251455, states[0] = -94.991653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648282903, states[0] = -95.025477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657378658, states[0] = -95.081417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669412567, states[0] = -95.091606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681625198, states[0] = -36.724402, states[40]= 0.000226
Saving checkpoint... 
Iteration: 693350207, states[0] = -95.069871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705168681, states[0] = -92.244838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717266248, states[0] = -95.008882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729459350, states[0] = -95.101201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741474642, states[0] = -95.103521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753157813, states[0] = -76.251187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765109241, states[0] = -22.028789, states[40]= 0.000883
Saving checkpoint... 
Iteration: 777114965, states[0] = -27.207250, states[40]= 0.000652
Saving checkpoint... 
Iteration: 788618444, states[0] = -30.387322, states[40]= 0.000490
Saving checkpoint... 
Iteration: 800460627, states[0] = -95.101362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812570276, states[0] = 5.499934, states[40]= 0.004697
Saving checkpoint... 
Iteration: 824557740, states[0] = 10.718606, states[40]= 0.004867
Saving checkpoint... 
Iteration: 833249934, states[0] = -94.989594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842682790, states[0] = -94.839538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854660869, states[0] = -81.560649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866477478, states[0] = -95.103835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878150161, states[0] = -64.933888, states[40]= 0.000003
Saving checkpoint... 
Iteration: 890285656, states[0] = -95.027790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902331855, states[0] = -95.060416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914254303, states[0] = -94.995006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926198431, states[0] = -94.905237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938388911, states[0] = -95.084671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950406805, states[0] = -95.089914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962660763, states[0] = -81.372687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974599447, states[0] = -13.226250, states[40]= 0.001709
Saving checkpoint... 
Iteration: 986976199, states[0] = -95.103579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999095307, states[0] = -9.683684, states[40]= 0.002364
Saving checkpoint... 
Iteration: 1008369883, states[0] = -95.077965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020052348, states[0] = 12.761276, states[40]= 0.004901
Saving checkpoint... 
Iteration: 1031692498, states[0] = -94.892122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043659848, states[0] = -79.755295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055783460, states[0] = -95.025716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067745541, states[0] = -94.983697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079609359, states[0] = -22.135182, states[40]= 0.000878
Saving checkpoint... 
Iteration: 1091402630, states[0] = -95.088675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103537132, states[0] = 18.059882, states[40]= 0.005281
Saving checkpoint... 
Iteration: 1115630795, states[0] = -42.313395, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1127488382, states[0] = -95.105088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139553383, states[0] = 12.376045, states[40]= 0.004894
Saving checkpoint... 
Iteration: 1151331745, states[0] = -95.060192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163419638, states[0] = -95.093027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174029963, states[0] = 20.185394, states[40]= 0.005927
Saving checkpoint... 
Iteration: 1186252730, states[0] = -94.992888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198497078, states[0] = -95.106074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211060622, states[0] = 9.585558, states[40]= 0.004845
Saving checkpoint... 
Iteration: 1223753148, states[0] = -94.993382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236029949, states[0] = 20.189187, states[40]= 0.005929
Saving checkpoint... 
Iteration: 1253808002, states[0] = -95.045237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266102112, states[0] = -15.596162, states[40]= 0.001375
Saving checkpoint... 
Iteration: 1278624667, states[0] = -36.213742, states[40]= 0.000242
Saving checkpoint... 
Iteration: 1290852996, states[0] = -95.070756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303311995, states[0] = -95.047963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315624128, states[0] = -35.698355, states[40]= 0.000260
Saving checkpoint... 
Iteration: 1324926467, states[0] = -95.094499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336998712, states[0] = -95.106168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349362341, states[0] = -95.074747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361617927, states[0] = -29.912052, states[40]= 0.000514
Saving checkpoint... 
Iteration: 1374245556, states[0] = -94.983516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376681619, states[0] = -94.821262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389098549, states[0] = -12.439945, states[40]= 0.001840
Saving checkpoint... 
Iteration: 1402107182, states[0] = -20.169283, states[40]= 0.000977
Saving checkpoint... 
Iteration: 1411272927, states[0] = -95.015408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423478111, states[0] = -95.103558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432568717, states[0] = 6.196270, states[40]= 0.004732
Saving checkpoint... 
Iteration: 1444955299, states[0] = -95.100059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454381408, states[0] = -95.081852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466316463, states[0] = -95.050814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478370763, states[0] = -95.077994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490335969, states[0] = -95.062270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502946646, states[0] = -95.287861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515332848, states[0] = 17.705132, states[40]= 0.006625
Saving checkpoint... 
Iteration: 1518835795, states[0] = -95.295937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530421324, states[0] = -55.472032, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1542479565, states[0] = -95.219861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543708267, states[0] = -95.277993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555595893, states[0] = -27.383929, states[40]= 0.000623
Saving checkpoint... 
Iteration: 1567469049, states[0] = -95.364050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579415189, states[0] = -95.303260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591446319, states[0] = -95.346815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603469289, states[0] = -95.370753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615298519, states[0] = -30.704014, states[40]= 0.000459
Saving checkpoint... 
Iteration: 1627489989, states[0] = -95.388295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639920169, states[0] = -56.070348, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1652454233, states[0] = 6.949289, states[40]= 0.005486
Saving checkpoint... 
Iteration: 1664362477, states[0] = -95.367144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676127991, states[0] = 19.030747, states[40]= 0.007302
Saving checkpoint... 
Iteration: 1688598898, states[0] = -95.281263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700956353, states[0] = -95.361510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712971506, states[0] = -95.375402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724707085, states[0] = 26.278767, states[40]= 0.097682
Saving checkpoint... 
Iteration: 1737017402, states[0] = 22.387118, states[40]= 0.014019
Saving checkpoint... 
Iteration: 1749463438, states[0] = -95.195313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761162308, states[0] = -95.189890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771496200, states[0] = -95.393632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783316531, states[0] = -51.400814, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1795722690, states[0] = -95.320906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807615784, states[0] = -31.486017, states[40]= 0.000459
Saving checkpoint... 
Iteration: 1819748654, states[0] = -95.028708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831737203, states[0] = -95.001586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843726374, states[0] = -94.976271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855962994, states[0] = -95.115727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867785460, states[0] = -95.037375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879615213, states[0] = -27.841772, states[40]= 0.000620
Saving checkpoint... 
Iteration: 1891543603, states[0] = 15.824429, states[40]= 0.005026
Saving checkpoint... 
Iteration: 1904093360, states[0] = -8.268537, states[40]= 0.002664
Saving checkpoint... 
Iteration: 1915696452, states[0] = -94.902995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927467831, states[0] = -95.103495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940140963, states[0] = -53.723652, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1951929646, states[0] = -95.095610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961223011, states[0] = -94.950060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973507853, states[0] = 24.735214, states[40]= 0.086640
Saving checkpoint... 
Iteration: 1985510711, states[0] = 23.659380, states[40]= 0.044153
Saving checkpoint... 
Iteration: 1997887936, states[0] = -95.083835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010246534, states[0] = -94.984499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022079050, states[0] = 1.207615, states[40]= 0.004350
Saving checkpoint... 
Iteration: 2033958617, states[0] = -95.100247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045699074, states[0] = -94.905790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057720889, states[0] = -94.945808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069735612, states[0] = -94.969055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081601109, states[0] = -14.699684, states[40]= 0.001490
Saving checkpoint... 
Iteration: 2093342761, states[0] = -95.065328, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.981638
 - CaMKt in component CaMK (millimolar): 0.007185
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.670021
 - nass in component intracellular_ions (millimolar): 6.670082
 - ki in component intracellular_ions (millimolar): 145.305640
 - kss in component intracellular_ions (millimolar): 145.305619
 - cansr in component intracellular_ions (millimolar): 1.320096
 - cajsr in component intracellular_ions (millimolar): 1.281202
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003589
 - hf in component INa (dimensionless): 0.881378
 - hs in component INa (dimensionless): 0.881374
 - j in component INa (dimensionless): 0.881347
 - hsp in component INa (dimensionless): 0.728433
 - jp in component INa (dimensionless): 0.881328
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710635
 - hLp in component INaL (dimensionless): 0.450288
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.614871
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.688331
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927693
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999861
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001639
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340787
 - xs1 in component IKs (dimensionless): 0.256428
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997316
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:07:42 (27552): called boinc_finish(0)

</stderr_txt>
]]>


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