𝕏

Task 54785704

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_564_1
Workunit 26012714
Created 26 Jun 2024, 4:45:50 UTC
Sent 26 Jun 2024, 6:59:02 UTC
Report deadline 29 Jun 2024, 16:35:02 UTC
Received 27 Jun 2024, 13:08:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216581
Run time 1 hours 19 min 22 sec
CPU time 1 hours 3 min 47 sec
Validate state Valid
Credit 57.18
Device peak FLOPS 5.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.51 MB
Peak swap size 1.54 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_564.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_564_1_r2137954503_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_564_1_r2137954503_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.462551
     * GNaL_b in INaL: 0.005892
     * Gto_b in Ito: 0.088095
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032290
     * GKs_b in IKs: 0.001865
     * GK1_b in IK1: 0.163868
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 65.997628
     * GKb_b in IKb: 0.003899
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033552
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9669526, states[0] = -94.706244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21949538, states[0] = -95.059540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34367690, states[0] = -95.022660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45818563, states[0] = -94.989125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57990128, states[0] = -95.039466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69984544, states[0] = -95.035073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81660798, states[0] = -89.735885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93632055, states[0] = -50.611207, states[40]= 0.000027
Saving checkpoint... 
Iteration: 105437707, states[0] = -95.021425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117758066, states[0] = -94.918117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129868869, states[0] = -94.999195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141654953, states[0] = -79.847051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153854449, states[0] = -94.992116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165687068, states[0] = -94.790704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175489849, states[0] = -95.027536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188074901, states[0] = 0.543996, states[40]= 0.004309
Saving checkpoint... 
Iteration: 201370518, states[0] = -94.998485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214457719, states[0] = -95.022316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226670997, states[0] = -94.457513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239456100, states[0] = -95.021939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249081841, states[0] = -3.700758, states[40]= 0.003650
Saving checkpoint... 
Iteration: 261913128, states[0] = -95.012369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274675010, states[0] = -94.680324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287771770, states[0] = -94.931504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300232549, states[0] = -94.880037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312431794, states[0] = -95.016913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321300878, states[0] = -94.958297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333742632, states[0] = -94.895254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346157538, states[0] = -84.201912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358353951, states[0] = -94.990968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370366001, states[0] = -94.996311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382921862, states[0] = -95.014500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395678870, states[0] = -94.748547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408083500, states[0] = -4.857496, states[40]= 0.003423
Saving checkpoint... 
Iteration: 420173264, states[0] = -94.614011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432710756, states[0] = -94.841472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445472848, states[0] = -95.024509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457289139, states[0] = -94.948313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470110584, states[0] = -29.009853, states[40]= 0.000535
Saving checkpoint... 
Iteration: 480068188, states[0] = 3.996737, states[40]= 0.004625
Saving checkpoint... 
Iteration: 491977697, states[0] = -95.025202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501750293, states[0] = -94.905712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513744935, states[0] = -94.898383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526330173, states[0] = -94.978262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538380924, states[0] = -95.002014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550668873, states[0] = -94.172134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562779843, states[0] = -94.939533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574737226, states[0] = -94.887081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586916380, states[0] = -95.012949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599334035, states[0] = -94.980452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611337043, states[0] = -94.982134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623660829, states[0] = -89.211397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635735575, states[0] = -94.884508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648019529, states[0] = 21.074504, states[40]= 0.009288
Saving checkpoint... 
Iteration: 660546991, states[0] = 12.806496, states[40]= 0.004900
Saving checkpoint... 
Iteration: 672709101, states[0] = -94.838056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681471134, states[0] = -95.024063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690761761, states[0] = -94.919945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702823717, states[0] = -94.974179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714953745, states[0] = -95.021084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727098377, states[0] = -17.601750, states[40]= 0.001170
Saving checkpoint... 
Iteration: 739093319, states[0] = -12.929167, states[40]= 0.001786
Saving checkpoint... 
Iteration: 751454233, states[0] = -95.021146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763749014, states[0] = -94.903801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775981965, states[0] = -95.025601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787993850, states[0] = -95.027177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800266961, states[0] = -94.925843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812481570, states[0] = -95.025517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824569895, states[0] = 3.167241, states[40]= 0.004566
Saving checkpoint... 
Iteration: 837010771, states[0] = 22.382576, states[40]= 0.042651
Saving checkpoint... 
Iteration: 849943401, states[0] = -95.018982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858895728, states[0] = -95.006798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871326526, states[0] = -94.975800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883058599, states[0] = 8.249160, states[40]= 0.004805
Saving checkpoint... 
Iteration: 895173741, states[0] = -94.635175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907203624, states[0] = -94.826880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918998837, states[0] = -95.027690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931361840, states[0] = -94.994103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943284587, states[0] = -94.943785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955229531, states[0] = -94.874655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967337359, states[0] = -94.982037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979711131, states[0] = -94.841778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991941454, states[0] = -95.018475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003773281, states[0] = -94.932538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015953069, states[0] = -95.020730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027536371, states[0] = 16.594577, states[40]= 0.005203
Saving checkpoint... 
Iteration: 1040272234, states[0] = -94.931406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052827087, states[0] = -94.976005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065606945, states[0] = -25.604977, states[40]= 0.000698
Saving checkpoint... 
Iteration: 1078223284, states[0] = -94.864020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091104528, states[0] = -23.349142, states[40]= 0.000801
Saving checkpoint... 
Iteration: 1108794957, states[0] = -94.952856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121138506, states[0] = -57.365515, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1134122942, states[0] = -40.854908, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1146547703, states[0] = 12.539576, states[40]= 0.004892
Saving checkpoint... 
Iteration: 1158858248, states[0] = -94.992336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171230292, states[0] = -94.875730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180842600, states[0] = -94.984696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193653297, states[0] = -76.893092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206267367, states[0] = -94.925986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219408268, states[0] = -95.010269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232271407, states[0] = -94.930378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234364188, states[0] = -94.994885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246794288, states[0] = -94.952186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259306124, states[0] = -94.961624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268888722, states[0] = -95.004194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281205693, states[0] = -94.830800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290718889, states[0] = -94.856062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303390793, states[0] = -95.004861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312698042, states[0] = -94.814893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324742042, states[0] = -94.893641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336890195, states[0] = -95.004636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348875266, states[0] = -94.999282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361650645, states[0] = -72.695643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374322435, states[0] = -94.972853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378159957, states[0] = -88.033535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390095410, states[0] = -14.842541, states[40]= 0.001492
Saving checkpoint... 
Iteration: 1402733605, states[0] = -94.880851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403981906, states[0] = -95.025115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416339070, states[0] = -94.982632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428503296, states[0] = 33.929070, states[40]= 0.166906
Saving checkpoint... 
Iteration: 1440755857, states[0] = -94.912181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452907894, states[0] = -95.009986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465507366, states[0] = 23.805649, states[40]= 0.098484
Saving checkpoint... 
Iteration: 1477647394, states[0] = -68.087724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490090270, states[0] = -10.227144, states[40]= 0.002290
Saving checkpoint... 
Iteration: 1502781616, states[0] = -14.319471, states[40]= 0.001705
Saving checkpoint... 
Iteration: 1515628652, states[0] = 18.056694, states[40]= 0.007013
Saving checkpoint... 
Iteration: 1527678245, states[0] = -12.663617, states[40]= 0.002065
Saving checkpoint... 
Iteration: 1539734846, states[0] = -83.529186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552310896, states[0] = -49.474466, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1564333857, states[0] = -83.004465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576366416, states[0] = -95.102758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588463477, states[0] = -95.272309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601423922, states[0] = 19.323804, states[40]= 0.008041
Saving checkpoint... 
Iteration: 1613775179, states[0] = -10.853868, states[40]= 0.002457
Saving checkpoint... 
Iteration: 1626052454, states[0] = 6.136280, states[40]= 0.005430
Saving checkpoint... 
Iteration: 1635425958, states[0] = -70.167534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1647345075, states[0] = 10.039937, states[40]= 0.005697
Saving checkpoint... 
Iteration: 1659937307, states[0] = 13.805099, states[40]= 0.006063
Saving checkpoint... 
Iteration: 1672144367, states[0] = -95.256187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684515573, states[0] = 21.736673, states[40]= 0.017133
Saving checkpoint... 
Iteration: 1696603502, states[0] = -41.713184, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1708823843, states[0] = 19.319975, states[40]= 0.008061
Saving checkpoint... 
Iteration: 1720834874, states[0] = 14.908528, states[40]= 0.006231
Saving checkpoint... 
Iteration: 1733022838, states[0] = -95.227592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745223175, states[0] = -66.148588, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1757852380, states[0] = -95.018210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770035412, states[0] = 14.666029, states[40]= 0.006190
Saving checkpoint... 
Iteration: 1781825996, states[0] = -70.316273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1793839034, states[0] = -91.589731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806403745, states[0] = -95.061435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818473557, states[0] = -95.063948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827829710, states[0] = -95.008283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840152209, states[0] = -77.764089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852161679, states[0] = -91.383562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864735784, states[0] = -94.894862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877669023, states[0] = -94.291960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889939824, states[0] = -95.022583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902361109, states[0] = -94.996610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914547912, states[0] = 12.419113, states[40]= 0.004890
Saving checkpoint... 
Iteration: 1926649726, states[0] = -71.526217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1939067338, states[0] = 4.370756, states[40]= 0.004650
Saving checkpoint... 
Iteration: 1951408174, states[0] = -95.010495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963558903, states[0] = 8.110696, states[40]= 0.004802
Saving checkpoint... 
Iteration: 1972271181, states[0] = -94.929988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981399075, states[0] = -95.007286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990400023, states[0] = -95.007484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002327317, states[0] = -94.975552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014598611, states[0] = -17.827460, states[40]= 0.001149
Saving checkpoint... 
Iteration: 2026816588, states[0] = -94.968536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038800770, states[0] = -94.956893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050978487, states[0] = -95.024109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063456882, states[0] = -95.020589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076300728, states[0] = -94.956784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088791061, states[0] = -94.948709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099133052, states[0] = -51.371938, states[40]= 0.000024
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.902746
 - CaMKt in component CaMK (millimolar): 0.007340
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.710362
 - nass in component intracellular_ions (millimolar): 6.710424
 - ki in component intracellular_ions (millimolar): 145.260785
 - kss in component intracellular_ions (millimolar): 145.260765
 - cansr in component intracellular_ions (millimolar): 1.335662
 - cajsr in component intracellular_ions (millimolar): 1.297266
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880016
 - hs in component INa (dimensionless): 0.880012
 - j in component INa (dimensionless): 0.879982
 - hsp in component INa (dimensionless): 0.725859
 - jp in component INa (dimensionless): 0.879962
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709757
 - hLp in component INaL (dimensionless): 0.451492
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620560
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695493
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935486
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001693
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323882
 - xs1 in component IKs (dimensionless): 0.241943
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:24:07 (14916): called boinc_finish(0)

</stderr_txt>
]]>


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