𝕏

Task 54782944

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_945_0
Workunit 26011335
Created 26 Jun 2024, 4:44:12 UTC
Sent 26 Jun 2024, 6:44:04 UTC
Report deadline 29 Jun 2024, 16:20:04 UTC
Received 26 Jun 2024, 9:13:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 29 min 6 sec
CPU time 2 hours 27 min 6 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_945.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_945_0_r913910484_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-Pueyo_APDR-conf_945_0_r913910484_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.128869
     * GNaL_b in INaL: 0.007706
     * Gto_b in Ito: 0.082229
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033804
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.147244
     * Gncx_b in INaCa_i: 0.000946
     * Pnak_b in INaK: 61.728832
     * GKb_b in IKb: 0.003879
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051794
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14564025, states[0] = 6.322719, states[40]= 0.004750
Saving checkpoint... 
Iteration: 29154789, states[0] = -80.933786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43996906, states[0] = -95.109738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58969046, states[0] = -95.100066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73835213, states[0] = -95.053107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88676112, states[0] = -94.717864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103410591, states[0] = -95.079977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118691092, states[0] = -94.861578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134124316, states[0] = -41.002719, states[40]= 0.000120
Saving checkpoint... 
Iteration: 149417230, states[0] = -95.079549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164507127, states[0] = 25.230389, states[40]= 0.101356
Saving checkpoint... 
Iteration: 179792415, states[0] = -95.015694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194686933, states[0] = -94.846690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209550368, states[0] = 12.616763, states[40]= 0.004936
Saving checkpoint... 
Iteration: 224924427, states[0] = -95.080578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240489196, states[0] = -95.092389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256073343, states[0] = 2.578064, states[40]= 0.004533
Saving checkpoint... 
Iteration: 271564370, states[0] = 6.866899, states[40]= 0.004800
Saving checkpoint... 
Iteration: 287074915, states[0] = 1.749014, states[40]= 0.004454
Saving checkpoint... 
Iteration: 302636521, states[0] = -54.409930, states[40]= 0.000015
Saving checkpoint... 
Iteration: 318203316, states[0] = -94.887331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333918292, states[0] = -95.078855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349590325, states[0] = -8.614622, states[40]= 0.002626
Saving checkpoint... 
Iteration: 364695014, states[0] = -94.869086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379049098, states[0] = 13.105917, states[40]= 0.004949
Saving checkpoint... 
Iteration: 393619867, states[0] = -36.423995, states[40]= 0.000228
Saving checkpoint... 
Iteration: 408475307, states[0] = -95.090238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422821451, states[0] = -95.037419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437140922, states[0] = -59.556332, states[40]= 0.000006
Saving checkpoint... 
Iteration: 451368164, states[0] = -95.062115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465661209, states[0] = -88.369417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479882612, states[0] = -95.067734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494190957, states[0] = -94.858912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508557233, states[0] = 9.901124, states[40]= 0.004885
Saving checkpoint... 
Iteration: 522760988, states[0] = -94.982238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537216532, states[0] = -94.913562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551526816, states[0] = 20.577375, states[40]= 0.006366
Saving checkpoint... 
Iteration: 565924355, states[0] = -95.080217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580410166, states[0] = -95.076486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594613872, states[0] = -30.586278, states[40]= 0.000461
Saving checkpoint... 
Iteration: 608803046, states[0] = -95.023944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622722042, states[0] = -94.923688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636869497, states[0] = -95.062539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650954741, states[0] = -95.086632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664887133, states[0] = -95.069215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678833430, states[0] = -95.044694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693444977, states[0] = -95.084721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707731806, states[0] = -94.940469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721938032, states[0] = -95.083253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736212421, states[0] = -94.905504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750685811, states[0] = -94.841428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765145194, states[0] = -64.762172, states[40]= 0.000002
Saving checkpoint... 
Iteration: 779611470, states[0] = -28.285877, states[40]= 0.000572
Saving checkpoint... 
Iteration: 794126925, states[0] = -43.673942, states[40]= 0.000081
Saving checkpoint... 
Iteration: 808763118, states[0] = -94.984616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823505723, states[0] = 27.003991, states[40]= 0.135717
Saving checkpoint... 
Iteration: 838289783, states[0] = -95.012503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852760568, states[0] = -94.981491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867456055, states[0] = -95.086721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882204809, states[0] = -94.890043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896533708, states[0] = 18.567190, states[40]= 0.005494
Saving checkpoint... 
Iteration: 911060862, states[0] = 8.390712, states[40]= 0.004850
Saving checkpoint... 
Iteration: 925511980, states[0] = 23.337306, states[40]= 0.032153
Saving checkpoint... 
Iteration: 939952419, states[0] = -95.085998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954483547, states[0] = -95.091054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968937504, states[0] = -95.082966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983682103, states[0] = -94.818400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998142430, states[0] = -61.361074, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1012785210, states[0] = -95.008123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027119346, states[0] = -35.908143, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1041737898, states[0] = -94.949967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056323912, states[0] = -95.038579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070608473, states[0] = -25.432513, states[40]= 0.000706
Saving checkpoint... 
Iteration: 1085171891, states[0] = -94.400872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099887724, states[0] = -95.069116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114246518, states[0] = -94.962716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128572401, states[0] = 3.063184, states[40]= 0.004575
Saving checkpoint... 
Iteration: 1142780783, states[0] = -95.003715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156908309, states[0] = -95.075557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171220173, states[0] = -94.919901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185719117, states[0] = -94.917945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200498088, states[0] = -95.092776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215108266, states[0] = -25.235860, states[40]= 0.000715
Saving checkpoint... 
Iteration: 1229502161, states[0] = 42.314788, states[40]= 0.113919
Saving checkpoint... 
Iteration: 1244200365, states[0] = -94.880391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259019138, states[0] = 22.266043, states[40]= 0.009963
Saving checkpoint... 
Iteration: 1274148915, states[0] = -69.633424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288979144, states[0] = -95.090191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304170273, states[0] = -94.155981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319504518, states[0] = 29.809904, states[40]= 0.160487
Saving checkpoint... 
Iteration: 1334993820, states[0] = -95.092154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349751493, states[0] = -94.969442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364665528, states[0] = -92.429388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379140221, states[0] = -58.725112, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1393479645, states[0] = -95.090191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408934855, states[0] = -95.082077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423920705, states[0] = -95.078706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438898584, states[0] = -95.072455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453443460, states[0] = -95.083881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467990905, states[0] = -95.091687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482777908, states[0] = -95.000565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497506124, states[0] = 26.375051, states[40]= 0.125724
Saving checkpoint... 
Iteration: 1511777230, states[0] = -9.152646, states[40]= 0.002806
Saving checkpoint... 
Iteration: 1526022254, states[0] = -95.287378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540279868, states[0] = -13.345350, states[40]= 0.001947
Saving checkpoint... 
Iteration: 1554581225, states[0] = -95.378683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569085591, states[0] = -20.215475, states[40]= 0.001044
Saving checkpoint... 
Iteration: 1584346596, states[0] = 10.203630, states[40]= 0.005745
Saving checkpoint... 
Iteration: 1599495705, states[0] = -95.274970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614281831, states[0] = -95.393829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628642098, states[0] = -95.354379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643423612, states[0] = 20.288201, states[40]= 0.008335
Saving checkpoint... 
Iteration: 1658299858, states[0] = -95.287245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673075714, states[0] = -95.390953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687542924, states[0] = 11.958055, states[40]= 0.005887
Saving checkpoint... 
Iteration: 1702200798, states[0] = 42.671609, states[40]= 0.012425
Saving checkpoint... 
Iteration: 1716798551, states[0] = -95.285111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731599606, states[0] = -95.409528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745695589, states[0] = -95.406787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759713144, states[0] = -95.312867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774355052, states[0] = -95.123640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789063386, states[0] = -95.193710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803884758, states[0] = -95.137397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818594638, states[0] = -14.850353, states[40]= 0.001515
Saving checkpoint... 
Iteration: 1833381041, states[0] = -95.099990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848306486, states[0] = -95.048089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862869439, states[0] = -95.076420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877577508, states[0] = 0.052907, states[40]= 0.004266
Saving checkpoint... 
Iteration: 1892063503, states[0] = 7.127561, states[40]= 0.004815
Saving checkpoint... 
Iteration: 1906924003, states[0] = -95.083443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921305712, states[0] = -95.027949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935819172, states[0] = -95.036703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950514686, states[0] = 22.937447, states[40]= 0.018547
Saving checkpoint... 
Iteration: 1965011059, states[0] = 23.500046, states[40]= 0.039666
Saving checkpoint... 
Iteration: 1979313891, states[0] = -95.031648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993904180, states[0] = -95.074081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008492665, states[0] = -95.091718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022776379, states[0] = -94.998700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036696275, states[0] = -94.870844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050644753, states[0] = -64.214282, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2064575464, states[0] = 1.451874, states[40]= 0.004423
Saving checkpoint... 
Iteration: 2078704663, states[0] = -94.888855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092637645, states[0] = -55.710845, states[40]= 0.000012
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.968197
 - CaMKt in component CaMK (millimolar): 0.007231
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.776144
 - nass in component intracellular_ions (millimolar): 6.776205
 - ki in component intracellular_ions (millimolar): 145.197631
 - kss in component intracellular_ions (millimolar): 145.197609
 - cansr in component intracellular_ions (millimolar): 1.326236
 - cajsr in component intracellular_ions (millimolar): 1.287835
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003594
 - hf in component INa (dimensionless): 0.881147
 - hs in component INa (dimensionless): 0.881142
 - j in component INa (dimensionless): 0.881113
 - hsp in component INa (dimensionless): 0.727994
 - jp in component INa (dimensionless): 0.881093
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711217
 - hLp in component INaL (dimensionless): 0.452585
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.619723
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.694028
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931603
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999877
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001654
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331772
 - xs1 in component IKs (dimensionless): 0.247677
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997320
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:13:13 (527083): called boinc_finish(0)

</stderr_txt>
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