𝕏

Task 54776342

Name HuVeMOp_20240622140139099418_ORdGradInc_k_23-Pueyo_APDR-conf_521_2
Workunit 25774745
Created 25 Jun 2024, 23:12:32 UTC
Sent 26 Jun 2024, 5:55:32 UTC
Report deadline 29 Jun 2024, 15:31:32 UTC
Received 28 Jun 2024, 13:03:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 32 min 3 sec
CPU time 2 hours 30 min 40 sec
Validate state Valid
Credit 54.11
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.41 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622140139099418_ORdGradInc_k_23-Pueyo_APDR-conf_521.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622140139099418_ORdGradInc_k_23-Pueyo_APDR-conf_521_2_r2123952727_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622140139099418_ORdGradInc_k_23-Pueyo_APDR-conf_521_2_r2123952727_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 66.604540
     * GNaL_b in INaL: 0.003554
     * Gto_b in Ito: 0.038663
     * PCa_b in ICaL: 0.000082
     * GKr_b in IKr: 0.034658
     * GKs_b in IKs: 0.001751
     * GK1_b in IK1: 0.121369
     * Gncx_b in INaCa_i: 0.000914
     * Pnak_b in INaK: 52.183170
     * GKb_b in IKb: 0.003558
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016308
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14652425, states[0] = -89.265173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31693774, states[0] = -94.078534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49689705, states[0] = -94.075589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65574250, states[0] = -5.717705, states[40]= 0.003593
Saving checkpoint... 
Iteration: 81491305, states[0] = -94.368892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96792643, states[0] = -94.279128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112447289, states[0] = -94.365775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129875587, states[0] = -94.343080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146015032, states[0] = 26.154752, states[40]= 0.015385
Saving checkpoint... 
Iteration: 162226173, states[0] = -94.182793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177729980, states[0] = -94.190966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193098391, states[0] = -31.946935, states[40]= 0.000373
Saving checkpoint... 
Iteration: 209285874, states[0] = -94.277588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225462080, states[0] = -94.372948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240969509, states[0] = -94.374446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256357311, states[0] = -94.336223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274110194, states[0] = -44.769830, states[40]= 0.000064
Saving checkpoint... 
Iteration: 288876616, states[0] = -94.346145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303879068, states[0] = -94.347276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318452563, states[0] = -94.371089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333560803, states[0] = 3.696499, states[40]= 0.005143
Saving checkpoint... 
Iteration: 348707753, states[0] = -94.142297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363932030, states[0] = -94.366041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378771026, states[0] = -94.259437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393843529, states[0] = -94.327918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409132614, states[0] = -68.666711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424799212, states[0] = -94.292065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441057626, states[0] = 5.563689, states[40]= 0.005289
Saving checkpoint... 
Iteration: 457441850, states[0] = -94.368500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472618507, states[0] = -53.695050, states[40]= 0.000015
Saving checkpoint... 
Iteration: 489838504, states[0] = -94.324524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506567483, states[0] = -0.662789, states[40]= 0.004609
Saving checkpoint... 
Iteration: 521080372, states[0] = -12.122988, states[40]= 0.002141
Saving checkpoint... 
Iteration: 539038210, states[0] = 15.735141, states[40]= 0.005856
Saving checkpoint... 
Iteration: 554070953, states[0] = -3.281035, states[40]= 0.004132
Saving checkpoint... 
Iteration: 569106937, states[0] = -41.247225, states[40]= 0.000109
Saving checkpoint... 
Iteration: 583992460, states[0] = -94.378107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599778516, states[0] = -94.268867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616391972, states[0] = -94.352554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633521395, states[0] = 23.493051, states[40]= 0.008206
Saving checkpoint... 
Iteration: 649045103, states[0] = 12.278686, states[40]= 0.005632
Saving checkpoint... 
Iteration: 665897751, states[0] = -94.354764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683366690, states[0] = -94.341009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699875536, states[0] = -94.345341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715329328, states[0] = -94.317837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731177557, states[0] = -94.050100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746677771, states[0] = -94.051308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762656059, states[0] = -92.380740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779412795, states[0] = -94.359967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796904734, states[0] = -94.357210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814907544, states[0] = -94.358176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832511429, states[0] = 27.738560, states[40]= 0.030736
Saving checkpoint... 
Iteration: 847141698, states[0] = -79.470747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862324756, states[0] = -94.314249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878531142, states[0] = 19.133899, states[40]= 0.006287
Saving checkpoint... 
Iteration: 893712563, states[0] = -94.153298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909066359, states[0] = 0.125018, states[40]= 0.004729
Saving checkpoint... 
Iteration: 925166161, states[0] = -93.853023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942285566, states[0] = -94.276979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957901205, states[0] = -94.355804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974655006, states[0] = -91.987966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993045752, states[0] = 11.946779, states[40]= 0.005615
Saving checkpoint... 
Iteration: 1008635424, states[0] = -71.845114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1023831665, states[0] = -94.319287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040781850, states[0] = -94.272542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058548322, states[0] = 10.619072, states[40]= 0.005553
Saving checkpoint... 
Iteration: 1076496588, states[0] = -94.378280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091284454, states[0] = -94.275567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107654239, states[0] = -91.651976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124111840, states[0] = -46.551133, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1140911056, states[0] = -94.359088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156470743, states[0] = -94.374063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173791781, states[0] = -94.283706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189563730, states[0] = 1.873937, states[40]= 0.004957
Saving checkpoint... 
Iteration: 1206067377, states[0] = -0.586986, states[40]= 0.004621
Saving checkpoint... 
Iteration: 1223791618, states[0] = -94.283487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240318086, states[0] = -94.308584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256443900, states[0] = -94.368324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273994967, states[0] = -94.377885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291087737, states[0] = -20.203427, states[40]= 0.001010
Saving checkpoint... 
Iteration: 1307863236, states[0] = -94.338679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326506939, states[0] = 30.745674, states[40]= 0.092330
Saving checkpoint... 
Iteration: 1341868785, states[0] = -94.341515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357983852, states[0] = -94.376139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374570184, states[0] = -2.673415, states[40]= 0.004252
Saving checkpoint... 
Iteration: 1390491224, states[0] = -94.377245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406703391, states[0] = -94.130667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422719893, states[0] = -94.169489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438319541, states[0] = -94.309613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452851417, states[0] = -94.331909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468541400, states[0] = 14.151460, states[40]= 0.005738
Saving checkpoint... 
Iteration: 1485185293, states[0] = -94.081398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501341552, states[0] = -92.810484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518674333, states[0] = -16.338392, states[40]= 0.001567
Saving checkpoint... 
Iteration: 1533991533, states[0] = -38.077470, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1550346023, states[0] = -94.682344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565568717, states[0] = -94.509900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581732095, states[0] = -88.712688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597123115, states[0] = -94.659957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612802890, states[0] = 38.666640, states[40]= 0.161808
Saving checkpoint... 
Iteration: 1627464956, states[0] = -94.728264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643725749, states[0] = 20.254041, states[40]= 0.008035
Saving checkpoint... 
Iteration: 1658902465, states[0] = -94.620430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675419673, states[0] = -94.658698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691822484, states[0] = -76.920713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708377101, states[0] = -94.551890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727353142, states[0] = -94.715294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744825977, states[0] = 20.120528, states[40]= 0.007987
Saving checkpoint... 
Iteration: 1760662727, states[0] = -94.727976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776179406, states[0] = -94.559057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790351439, states[0] = -94.712971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805401371, states[0] = -94.422170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821077017, states[0] = -10.262837, states[40]= 0.002562
Saving checkpoint... 
Iteration: 1838268506, states[0] = -94.288435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853399142, states[0] = -94.377347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868192210, states[0] = -94.116845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883516737, states[0] = 25.374996, states[40]= 0.012080
Saving checkpoint... 
Iteration: 1900718322, states[0] = -94.172420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915730229, states[0] = -94.195422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930707162, states[0] = -94.142625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945838564, states[0] = -94.325405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961219421, states[0] = -94.169365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977534724, states[0] = 17.424268, states[40]= 0.006030
Saving checkpoint... 
Iteration: 1992659777, states[0] = -93.281285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009607805, states[0] = -42.201542, states[40]= 0.000095
Saving checkpoint... 
Iteration: 2029359319, states[0] = -94.336113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046502510, states[0] = 39.446557, states[40]= 0.179241
Saving checkpoint... 
Iteration: 2063178653, states[0] = -94.054917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079548133, states[0] = 10.717070, states[40]= 0.005558
Saving checkpoint... 
Iteration: 2096068650, states[0] = -1.509820, states[40]= 0.004467
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.253708
 - CaMKt in component CaMK (millimolar): 0.007141
 - cass in component intracellular_ions (millimolar): 0.000076
 - nai in component intracellular_ions (millimolar): 7.156280
 - nass in component intracellular_ions (millimolar): 7.156336
 - ki in component intracellular_ions (millimolar): 144.809635
 - kss in component intracellular_ions (millimolar): 144.809619
 - cansr in component intracellular_ions (millimolar): 1.356397
 - cajsr in component intracellular_ions (millimolar): 1.320233
 - cai in component intracellular_ions (millimolar): 0.000077
 - m in component INa (dimensionless): 0.003863
 - hf in component INa (dimensionless): 0.868292
 - hs in component INa (dimensionless): 0.868286
 - j in component INa (dimensionless): 0.868249
 - hsp in component INa (dimensionless): 0.704131
 - jp in component INa (dimensionless): 0.868223
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.695197
 - hLp in component INaL (dimensionless): 0.440767
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.632183
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.707562
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940043
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999910
 - jca in component ICaL (dimensionless): 0.999985
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001818
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333113
 - xs1 in component IKs (dimensionless): 0.218178
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997502
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:03:37 (38125): called boinc_finish(0)

</stderr_txt>
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