𝕏

Task 54775800

Name HuVeMOp_20240622162040805470_ORdGradInc_k_23-CLVPET_Block_Ks_95-conf_98_2
Workunit 25787743
Created 25 Jun 2024, 19:55:47 UTC
Sent 26 Jun 2024, 5:49:44 UTC
Report deadline 29 Jun 2024, 8:42:32 UTC
Received 29 Jun 2024, 7:37:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223433
Run time 51 min 11 sec
CPU time 38 min 3 sec
Validate state Valid
Credit 48.77
Device peak FLOPS 5.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.53 MB
Peak swap size 391.76 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622162040805470_ORdGradInc_k_23-CLVPET_Block_Ks_95-conf_98.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622162040805470_ORdGradInc_k_23-CLVPET_Block_Ks_95-conf_98_2_r199672081_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622162040805470_ORdGradInc_k_23-CLVPET_Block_Ks_95-conf_98_2_r199672081_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 75.953497
     * GNaL_b in INaL: 0.007805
     * Gto_b in Ito: 0.089384
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030376
     * GKs_b in IKs: 0.000098
     * GK1_b in IK1: 0.123984
     * Gncx_b in INaCa_i: 0.000990
     * Pnak_b in INaK: 75.852454
     * GKb_b in IKb: 0.003866
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.071484
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5710291, states[0] = -94.263734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15589136, states[0] = 2.273809, states[40]= 0.004229
Saving checkpoint... 
Iteration: 27246809, states[0] = -94.172927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40102554, states[0] = -5.087811, states[40]= 0.003457
Saving checkpoint... 
Iteration: 49589661, states[0] = 3.143854, states[40]= 0.004234
Saving checkpoint... 
Iteration: 61128276, states[0] = -25.968812, states[40]= 0.001364
Saving checkpoint... 
Iteration: 71915981, states[0] = -94.401378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80970375, states[0] = -94.422493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90293732, states[0] = -94.243410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101580489, states[0] = 7.959600, states[40]= 0.004017
Saving checkpoint... 
Iteration: 109148430, states[0] = -42.639349, states[40]= 0.000281
Saving checkpoint... 
Iteration: 121551789, states[0] = 19.026157, states[40]= 0.002161
Saving checkpoint... 
Iteration: 127745479, states[0] = -94.095823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138707523, states[0] = -93.599408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150142951, states[0] = -37.667862, states[40]= 0.000538
Saving checkpoint... 
Iteration: 153198435, states[0] = -91.546422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163323757, states[0] = -94.292750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174251579, states[0] = -94.115477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186305963, states[0] = -94.260526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197978333, states[0] = -94.413483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208443423, states[0] = -94.400295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215925220, states[0] = -94.391201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226332070, states[0] = -94.304495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235711793, states[0] = -93.821120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244373319, states[0] = -94.353311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253295007, states[0] = -94.237021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262989960, states[0] = -94.416286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273420921, states[0] = -94.388414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285866663, states[0] = -94.346576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297180307, states[0] = -73.058602, states[40]= 0.000002
Saving checkpoint... 
Iteration: 307827443, states[0] = -94.297053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317738695, states[0] = -94.066409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328408761, states[0] = -94.380765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339687170, states[0] = -81.114571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349200745, states[0] = -92.409844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359047835, states[0] = 20.385326, states[40]= 0.001924
Saving checkpoint... 
Iteration: 362959569, states[0] = -94.406082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375169635, states[0] = -62.253504, states[40]= 0.000012
Saving checkpoint... 
Iteration: 383094753, states[0] = 0.786985, states[40]= 0.004234
Saving checkpoint... 
Iteration: 390626521, states[0] = -23.867802, states[40]= 0.001399
Saving checkpoint... 
Iteration: 401123456, states[0] = -21.324436, states[40]= 0.001367
Saving checkpoint... 
Iteration: 409909646, states[0] = -94.380997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418252342, states[0] = -94.116450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425468617, states[0] = -94.409076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437375584, states[0] = -94.354552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446776041, states[0] = -94.189522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456147975, states[0] = -42.042920, states[40]= 0.000305
Saving checkpoint... 
Iteration: 468245979, states[0] = -94.093508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474350552, states[0] = -94.327971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484620332, states[0] = -18.694507, states[40]= 0.001386
Saving checkpoint... 
Iteration: 496580678, states[0] = 7.949743, states[40]= 0.004037
Saving checkpoint... 
Iteration: 506577355, states[0] = 9.419633, states[40]= 0.003874
Saving checkpoint... 
Iteration: 518996881, states[0] = -94.416991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528582719, states[0] = 7.011967, states[40]= 0.004121
Saving checkpoint... 
Iteration: 539130728, states[0] = -27.336220, states[40]= 0.001337
Saving checkpoint... 
Iteration: 550827283, states[0] = -94.295796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561468713, states[0] = -94.408553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572450295, states[0] = -94.401544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582532644, states[0] = 25.189647, states[40]= 0.001244
Saving checkpoint... 
Iteration: 590789179, states[0] = -94.222255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595014904, states[0] = 28.181238, states[40]= 0.009229
Saving checkpoint... 
Iteration: 602484253, states[0] = -94.413264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612378721, states[0] = -94.356677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622123299, states[0] = -21.192600, states[40]= 0.001366
Saving checkpoint... 
Iteration: 631207068, states[0] = -93.548143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641287105, states[0] = -94.217099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651705282, states[0] = -93.355683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659835773, states[0] = -94.307917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667174219, states[0] = -66.695682, states[40]= 0.000006
Saving checkpoint... 
Iteration: 680319767, states[0] = -94.283121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691153375, states[0] = -46.983632, states[40]= 0.000152
Saving checkpoint... 
Iteration: 703336517, states[0] = -94.308785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705740385, states[0] = -94.071401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717840992, states[0] = -94.314848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727481324, states[0] = -94.411898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736016051, states[0] = 28.190785, states[40]= 0.006519
Saving checkpoint... 
Iteration: 746168723, states[0] = -61.385882, states[40]= 0.000014
Saving checkpoint... 
Iteration: 756597175, states[0] = -0.656888, states[40]= 0.004129
Saving checkpoint... 
Iteration: 767556313, states[0] = 17.501157, states[40]= 0.002475
Saving checkpoint... 
Iteration: 776941324, states[0] = -94.396782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786556414, states[0] = 17.466020, states[40]= 0.002482
Saving checkpoint... 
Iteration: 797612315, states[0] = -11.844703, states[40]= 0.002124
Saving checkpoint... 
Iteration: 808242785, states[0] = -94.080174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819725253, states[0] = -94.003872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823959458, states[0] = -94.404155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837453575, states[0] = -94.401805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849757084, states[0] = -94.130742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858577224, states[0] = 9.476738, states[40]= 0.003868
Saving checkpoint... 
Iteration: 866822218, states[0] = -94.286425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880355031, states[0] = -94.331572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887891337, states[0] = -94.366069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898234197, states[0] = -94.045741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908499681, states[0] = -94.416088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920418304, states[0] = -94.384223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931700442, states[0] = -92.307587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941100335, states[0] = -2.674500, states[40]= 0.003893
Saving checkpoint... 
Iteration: 946036899, states[0] = 23.923313, states[40]= 0.001385
Saving checkpoint... 
Iteration: 955436731, states[0] = -94.393892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965939593, states[0] = -94.395208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975115774, states[0] = -14.795119, states[40]= 0.001678
Saving checkpoint... 
Iteration: 986453698, states[0] = -94.401246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995723492, states[0] = -93.992586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006728007, states[0] = -94.017530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014860912, states[0] = -94.337560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025788915, states[0] = -94.219839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036987920, states[0] = -94.412524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046987212, states[0] = -94.412287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056941340, states[0] = -94.395645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061535108, states[0] = 24.468372, states[40]= 0.001320
Saving checkpoint... 
Iteration: 1071761092, states[0] = -94.142845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076604310, states[0] = -5.456786, states[40]= 0.003419
Saving checkpoint... 
Iteration: 1088899866, states[0] = -94.371603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098484850, states[0] = -94.411411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109380260, states[0] = -94.356003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119639345, states[0] = -34.528094, states[40]= 0.000775
Saving checkpoint... 
Iteration: 1129965467, states[0] = -94.405103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140371920, states[0] = -94.348233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145496904, states[0] = -94.414440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156326956, states[0] = -94.292802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165527049, states[0] = 26.656228, states[40]= 0.001192
Saving checkpoint... 
Iteration: 1177059858, states[0] = 16.252640, states[40]= 0.002725
Saving checkpoint... 
Iteration: 1181698554, states[0] = -91.560134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192561325, states[0] = 15.725696, states[40]= 0.002830
Saving checkpoint... 
Iteration: 1199201224, states[0] = -92.547344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207854815, states[0] = -94.329982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217257866, states[0] = -94.131803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229171203, states[0] = -63.747665, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1239345659, states[0] = -94.318785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248055409, states[0] = 17.815473, states[40]= 0.002413
Saving checkpoint... 
Iteration: 1257440545, states[0] = -94.394460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267723075, states[0] = -93.988735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276098181, states[0] = -1.280878, states[40]= 0.004067
Saving checkpoint... 
Iteration: 1288623178, states[0] = -21.089432, states[40]= 0.001365
Saving checkpoint... 
Iteration: 1293688581, states[0] = -82.802562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304734356, states[0] = -94.044717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314125769, states[0] = -23.243424, states[40]= 0.001392
Saving checkpoint... 
Iteration: 1324465895, states[0] = -94.404460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336585198, states[0] = 5.834831, states[40]= 0.004205
Saving checkpoint... 
Iteration: 1346268487, states[0] = -94.164389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358492975, states[0] = -94.412569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367888867, states[0] = -94.362155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375931772, states[0] = -94.389719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386501153, states[0] = 42.307089, states[40]= 0.242574
Saving checkpoint... 
Iteration: 1394066754, states[0] = 13.712710, states[40]= 0.003213
Saving checkpoint... 
Iteration: 1404292775, states[0] = -94.227221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408670600, states[0] = -63.168045, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1421476368, states[0] = -94.407550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431736848, states[0] = -94.054409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440663264, states[0] = -56.250939, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1452481486, states[0] = -94.408986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463205679, states[0] = -93.400214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473609091, states[0] = -9.166329, states[40]= 0.002650
Saving checkpoint... 
Iteration: 1484235993, states[0] = -94.050724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493905676, states[0] = -94.373961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504597298, states[0] = 14.722508, states[40]= 0.006316
Saving checkpoint... 
Iteration: 1516567788, states[0] = -74.107449, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1528907028, states[0] = -51.618130, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1530842649, states[0] = 1.105009, states[40]= 0.003895
Saving checkpoint... 
Iteration: 1540699713, states[0] = -94.269797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549882352, states[0] = -23.695449, states[40]= 0.001460
Saving checkpoint... 
Iteration: 1559626405, states[0] = -94.130171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568113676, states[0] = -5.916025, states[40]= 0.003128
Saving checkpoint... 
Iteration: 1577029741, states[0] = 25.984469, states[40]= 0.001153
Saving checkpoint... 
Iteration: 1587103259, states[0] = -93.968436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597076340, states[0] = -93.948204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606585957, states[0] = -93.938735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614337697, states[0] = -93.922088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626202795, states[0] = -93.830155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631591441, states[0] = -93.814584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641398519, states[0] = -93.808689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651887895, states[0] = -93.791961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661932229, states[0] = -93.785207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671611160, states[0] = -93.785082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679902388, states[0] = -93.773234, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -93.648575
 - CaMKt in component CaMK (millimolar): 0.001038
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.254408
 - nass in component intracellular_ions (millimolar): 6.254487
 - ki in component intracellular_ions (millimolar): 145.656225
 - kss in component intracellular_ions (millimolar): 145.656214
 - cansr in component intracellular_ions (millimolar): 1.496133
 - cajsr in component intracellular_ions (millimolar): 1.496231
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.004106
 - hf in component INa (dimensionless): 0.856497
 - hs in component INa (dimensionless): 0.856497
 - j in component INa (dimensionless): 0.856499
 - hsp in component INa (dimensionless): 0.683038
 - jp in component INa (dimensionless): 0.856500
 - mL in component INaL (dimensionless): 0.000063
 - hL in component INaL (dimensionless): 0.694892
 - hLp in component INaL (dimensionless): 0.498706
 - a in component Ito (dimensionless): 0.000678
 - iF in component Ito (dimensionless): 0.999838
 - iS in component Ito (dimensionless): 0.997468
 - ap in component Ito (dimensionless): 0.000346
 - iFp in component Ito (dimensionless): 0.999838
 - iSp in component Ito (dimensionless): 0.999113
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998725
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002504
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002207
 - xs1 in component IKs (dimensionless): 0.025074
 - xs2 in component IKs (dimensionless): 0.000101
 - xk1 in component IK1 (dimensionless): 0.997647
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:37:10 (60298): called boinc_finish(0)

</stderr_txt>
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