𝕏

Task 54775136

Name HuVeMOp_20240622180134546707_ORdGradInc_k_23-Schmidt_333-conf_16_2
Workunit 25788459
Created 25 Jun 2024, 17:18:16 UTC
Sent 26 Jun 2024, 5:49:45 UTC
Report deadline 29 Jun 2024, 5:49:45 UTC
Received 28 Jun 2024, 22:59:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223433
Run time 46 min 34 sec
CPU time 33 min 43 sec
Validate state Valid
Credit 43.36
Device peak FLOPS 5.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.50 MB
Peak swap size 391.75 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622180134546707_ORdGradInc_k_23-Schmidt_333-conf_16.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622180134546707_ORdGradInc_k_23-Schmidt_333-conf_16_2_r1905492663_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622180134546707_ORdGradInc_k_23-Schmidt_333-conf_16_2_r1905492663_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 76.947020
     * GNaL_b in INaL: 0.002859
     * Gto_b in Ito: 0.048621
     * PCa_b in ICaL: 0.000083
     * GKr_b in IKr: 0.037547
     * GKs_b in IKs: 0.001684
     * GK1_b in IK1: 0.119767
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 75.485510
     * GKb_b in IKb: 0.004015
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.014310
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 3541223, states[0] = 15.881846, states[40]= 0.005625
Saving checkpoint... 
Iteration: 12518356, states[0] = 29.791260, states[40]= 0.001805
Saving checkpoint... 
Iteration: 22409745, states[0] = -21.079096, states[40]= 0.000204
Saving checkpoint... 
Iteration: 35763220, states[0] = -54.901750, states[40]= 0.000077
Saving checkpoint... 
Iteration: 43915438, states[0] = -32.391467, states[40]= 0.000024
Saving checkpoint... 
Iteration: 54711636, states[0] = 10.874005, states[40]= 0.000192
Saving checkpoint... 
Iteration: 60249598, states[0] = -36.756361, states[40]= 0.000022
Saving checkpoint... 
Iteration: 72349695, states[0] = 27.714386, states[40]= 0.000457
Saving checkpoint... 
Iteration: 82595536, states[0] = -57.006427, states[40]= 0.000005
Saving checkpoint... 
Iteration: 91965953, states[0] = -84.264892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102077821, states[0] = -39.596769, states[40]= 0.000224
Saving checkpoint... 
Iteration: 112417182, states[0] = -49.674856, states[40]= 0.000089
Saving checkpoint... 
Iteration: 123644876, states[0] = -84.686719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134580500, states[0] = -44.653104, states[40]= 0.000014
Saving checkpoint... 
Iteration: 146126555, states[0] = -84.567157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155077464, states[0] = -46.813899, states[40]= 0.000116
Saving checkpoint... 
Iteration: 163508437, states[0] = 27.958392, states[40]= 0.000156
Saving checkpoint... 
Iteration: 173136707, states[0] = -84.824876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178867737, states[0] = 10.467555, states[40]= 0.000003
Saving checkpoint... 
Iteration: 188070405, states[0] = -41.462811, states[40]= 0.000185
Saving checkpoint... 
Iteration: 198297204, states[0] = -84.548264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207886058, states[0] = -14.094919, states[40]= 0.000025
Saving checkpoint... 
Iteration: 218122818, states[0] = -84.652257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231103187, states[0] = -83.053670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236855142, states[0] = 15.516341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245729190, states[0] = -38.350593, states[40]= 0.000233
Saving checkpoint... 
Iteration: 253682836, states[0] = 17.058805, states[40]= 0.000031
Saving checkpoint... 
Iteration: 262358298, states[0] = 10.061260, states[40]= 0.000136
Saving checkpoint... 
Iteration: 272323656, states[0] = 30.141039, states[40]= 0.003899
Saving checkpoint... 
Iteration: 280709524, states[0] = -12.395609, states[40]= 0.000599
Saving checkpoint... 
Iteration: 291896213, states[0] = -42.115248, states[40]= 0.000017
Saving checkpoint... 
Iteration: 299079522, states[0] = -68.643175, states[40]= 0.000009
Saving checkpoint... 
Iteration: 309314353, states[0] = 31.194964, states[40]= 0.029142
Saving checkpoint... 
Iteration: 319381093, states[0] = -26.887807, states[40]= 0.000373
Saving checkpoint... 
Iteration: 331747016, states[0] = -73.722158, states[40]= 0.000005
Saving checkpoint... 
Iteration: 339887266, states[0] = -36.265408, states[40]= 0.000022
Saving checkpoint... 
Iteration: 349828834, states[0] = 24.965639, states[40]= 0.000019
Saving checkpoint... 
Iteration: 360347312, states[0] = 10.983604, states[40]= 0.000116
Saving checkpoint... 
Iteration: 369250160, states[0] = -77.141957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379951508, states[0] = -84.654813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390762487, states[0] = -84.283644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402215453, states[0] = -37.811727, states[40]= 0.000021
Saving checkpoint... 
Iteration: 406913589, states[0] = -77.622782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416568554, states[0] = -65.390450, states[40]= 0.000002
Saving checkpoint... 
Iteration: 425428247, states[0] = -84.418319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435795365, states[0] = 30.424074, states[40]= 0.361821
Saving checkpoint... 
Iteration: 447684874, states[0] = -1.009788, states[40]= 0.000567
Saving checkpoint... 
Iteration: 456573826, states[0] = -76.208608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 466057080, states[0] = -61.193692, states[40]= 0.000024
Saving checkpoint... 
Iteration: 476930274, states[0] = -84.371144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485739906, states[0] = -81.186489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495793559, states[0] = 31.137083, states[40]= 0.066833
Saving checkpoint... 
Iteration: 504920120, states[0] = -83.975642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516223268, states[0] = -62.908176, states[40]= 0.000003
Saving checkpoint... 
Iteration: 521228994, states[0] = -70.552680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529877916, states[0] = -49.448542, states[40]= 0.000010
Saving checkpoint... 
Iteration: 541872144, states[0] = -43.348849, states[40]= 0.000015
Saving checkpoint... 
Iteration: 553772582, states[0] = -84.906488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563638042, states[0] = 25.501587, states[40]= 0.000108
Saving checkpoint... 
Iteration: 569899692, states[0] = -79.553696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580296396, states[0] = 28.802545, states[40]= 0.001104
Saving checkpoint... 
Iteration: 590302684, states[0] = 25.147568, states[40]= 0.000087
Saving checkpoint... 
Iteration: 599290520, states[0] = 30.277669, states[40]= 0.004552
Saving checkpoint... 
Iteration: 610966599, states[0] = 25.527054, states[40]= 0.000109
Saving checkpoint... 
Iteration: 623052676, states[0] = -75.364642, states[40]= 0.000004
Saving checkpoint... 
Iteration: 633286366, states[0] = 30.492035, states[40]= 0.005960
Saving checkpoint... 
Iteration: 636105237, states[0] = 33.523171, states[40]= 1.208763
Saving checkpoint... 
Iteration: 645042523, states[0] = -65.542250, states[40]= 0.000014
Saving checkpoint... 
Iteration: 655014108, states[0] = -26.745881, states[40]= 0.000384
Saving checkpoint... 
Iteration: 665063749, states[0] = -83.822904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672732372, states[0] = -84.122780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683884210, states[0] = -75.938992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694878426, states[0] = -70.670858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 700318733, states[0] = 6.546360, states[40]= 0.000255
Saving checkpoint... 
Iteration: 710571876, states[0] = -84.291074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721554686, states[0] = -81.596264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730474491, states[0] = 14.086346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740838920, states[0] = -23.834996, states[40]= 0.000022
Saving checkpoint... 
Iteration: 747458455, states[0] = 23.421035, states[40]= 0.000007
Saving checkpoint... 
Iteration: 758294380, states[0] = 20.088713, states[40]= 0.000018
Saving checkpoint... 
Iteration: 770842495, states[0] = -33.767951, states[40]= 0.000023
Saving checkpoint... 
Iteration: 781140223, states[0] = 10.984972, states[40]= 0.000002
Saving checkpoint... 
Iteration: 790032740, states[0] = -71.537993, states[40]= 0.000006
Saving checkpoint... 
Iteration: 794627016, states[0] = 18.199914, states[40]= 0.000025
Saving checkpoint... 
Iteration: 804563706, states[0] = -84.330828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816524009, states[0] = -59.667223, states[40]= 0.000004
Saving checkpoint... 
Iteration: 827792270, states[0] = 18.111536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838823482, states[0] = -14.847740, states[40]= 0.000024
Saving checkpoint... 
Iteration: 850766740, states[0] = 30.539001, states[40]= 0.001713
Saving checkpoint... 
Iteration: 856525145, states[0] = -66.020945, states[40]= 0.000002
Saving checkpoint... 
Iteration: 862023862, states[0] = -69.428359, states[40]= 0.000009
Saving checkpoint... 
Iteration: 870300434, states[0] = 7.665053, states[40]= 0.000218
Saving checkpoint... 
Iteration: 882544964, states[0] = -83.451417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892731297, states[0] = -84.781209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902656579, states[0] = -27.646564, states[40]= 0.000382
Saving checkpoint... 
Iteration: 912728666, states[0] = -84.770211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922721386, states[0] = -84.660382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931915826, states[0] = 31.114957, states[40]= 0.083303
Saving checkpoint... 
Iteration: 939394854, states[0] = -84.802040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947797904, states[0] = 4.388474, states[40]= 0.000009
Saving checkpoint... 
Iteration: 958738191, states[0] = 26.338082, states[40]= 0.276838
Saving checkpoint... 
Iteration: 969906098, states[0] = 32.939352, states[40]= 0.674166
Saving checkpoint... 
Iteration: 975460762, states[0] = 5.372117, states[40]= 0.000007
Saving checkpoint... 
Iteration: 986746077, states[0] = 31.400284, states[40]= 0.032645
Saving checkpoint... 
Iteration: 995816374, states[0] = -28.334297, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1006572967, states[0] = 30.991201, states[40]= 0.173931
Saving checkpoint... 
Iteration: 1016850148, states[0] = -75.061514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025322457, states[0] = -44.965816, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1035128755, states[0] = -2.400219, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1046305306, states[0] = -21.833707, states[40]= 0.000433
Saving checkpoint... 
Iteration: 1057596450, states[0] = 20.921643, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1068388833, states[0] = -84.889575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078159250, states[0] = -53.013651, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1090858858, states[0] = -83.637576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095511263, states[0] = -77.345591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104906399, states[0] = 30.347322, states[40]= 0.004920
Saving checkpoint... 
Iteration: 1117232136, states[0] = 31.208756, states[40]= 0.048313
Saving checkpoint... 
Iteration: 1126636979, states[0] = -32.062340, states[40]= 0.000342
Saving checkpoint... 
Iteration: 1136978023, states[0] = -45.057749, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1148181887, states[0] = -82.720506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157534952, states[0] = -84.489721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168837599, states[0] = -77.637861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176419207, states[0] = 21.237237, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1185301119, states[0] = -37.170617, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1193780282, states[0] = -3.304609, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1202148924, states[0] = -55.607077, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1208153749, states[0] = -62.371932, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1219325956, states[0] = -74.858538, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1230763722, states[0] = 9.578715, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1235841802, states[0] = -83.197992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243692915, states[0] = -84.707503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252011649, states[0] = -84.340367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261814600, states[0] = -61.804288, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1272245650, states[0] = 18.372739, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1282269160, states[0] = -2.303101, states[40]= 0.000655
Saving checkpoint... 
Iteration: 1292601497, states[0] = -2.348141, states[40]= 0.000657
Saving checkpoint... 
Iteration: 1303004600, states[0] = -84.228055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1313674710, states[0] = -84.442609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316606994, states[0] = -14.130187, states[40]= 0.000600
Saving checkpoint... 
Iteration: 1325374989, states[0] = 30.591075, states[40]= 0.173254
Saving checkpoint... 
Iteration: 1332501597, states[0] = -83.646010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342244444, states[0] = 14.431859, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1355375850, states[0] = 31.404920, states[40]= 0.032762
Saving checkpoint... 
Iteration: 1365386913, states[0] = 28.627137, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1374734534, states[0] = 20.103814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383731327, states[0] = 21.544522, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1391808882, states[0] = -70.689675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401778486, states[0] = -32.328943, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1410353549, states[0] = -84.855235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419674620, states[0] = -84.685133, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429826446, states[0] = -83.783065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437736101, states[0] = 14.835475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1447179057, states[0] = -84.599826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1460443551, states[0] = -38.481470, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1470805104, states[0] = -75.328980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480673768, states[0] = -84.765818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1491303703, states[0] = -79.572021, states[40]= 0.000002
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.793259
 - CaMKt in component CaMK (millimolar): 0.207883
 - cass in component intracellular_ions (millimolar): 0.000161
 - nai in component intracellular_ions (millimolar): 7.109668
 - nass in component intracellular_ions (millimolar): 7.109995
 - ki in component intracellular_ions (millimolar): 144.021680
 - kss in component intracellular_ions (millimolar): 144.021644
 - cansr in component intracellular_ions (millimolar): 3.217172
 - cajsr in component intracellular_ions (millimolar): 1.946579
 - cai in component intracellular_ions (millimolar): 0.000152
 - m in component INa (dimensionless): 0.010011
 - hf in component INa (dimensionless): 0.582102
 - hs in component INa (dimensionless): 0.580802
 - j in component INa (dimensionless): 0.555712
 - hsp in component INa (dimensionless): 0.329447
 - jp in component INa (dimensionless): 0.519473
 - mL in component INaL (dimensionless): 0.000338
 - hL in component INaL (dimensionless): 0.191938
 - hLp in component INaL (dimensionless): 0.077244
 - a in component Ito (dimensionless): 0.001233
 - iF in component Ito (dimensionless): 0.999229
 - iS in component Ito (dimensionless): 0.142618
 - ap in component Ito (dimensionless): 0.000628
 - iFp in component Ito (dimensionless): 0.999230
 - iSp in component Ito (dimensionless): 0.159712
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.692843
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.935915
 - jca in component ICaL (dimensionless): 0.922972
 - ffp in component ICaL (dimensionless): 0.999448
 - fcafp in component ICaL (dimensionless): 0.999965
 - nca in component ICaL (dimensionless): 0.032834
 - xrf in component IKr (dimensionless): 0.082704
 - xrs in component IKr (dimensionless): 0.867838
 - xs1 in component IKs (dimensionless): 0.556899
 - xs2 in component IKs (dimensionless): 0.005041
 - xk1 in component IK1 (dimensionless): 0.996752
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:06:04 (53134): called boinc_finish(0)

</stderr_txt>
]]>


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