𝕏

Task 54770463

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396_1
Workunit 26006899
Created 25 Jun 2024, 10:01:39 UTC
Sent 26 Jun 2024, 5:05:43 UTC
Report deadline 29 Jun 2024, 7:58:31 UTC
Received 26 Jun 2024, 12:53:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 2 hours 11 min 12 sec
CPU time 2 hours 11 min 12 sec
Validate state Valid
Credit 48.21
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396_1_r450096049_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396_1_r450096049_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 109.367449
     * GNaL_b in INaL: 0.006830
     * Gto_b in Ito: 0.072090
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009789
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.160556
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 64.833553
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037451
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13483781, states[0] = -94.824074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25962903, states[0] = -94.775558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39364072, states[0] = -94.675748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52088179, states[0] = 11.046817, states[40]= 0.005367
Saving checkpoint... 
Iteration: 64916375, states[0] = -94.706617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76585545, states[0] = 12.222765, states[40]= 0.005322
Saving checkpoint... 
Iteration: 89227602, states[0] = -37.295282, states[40]= 0.001540
Saving checkpoint... 
Iteration: 100932122, states[0] = -94.704550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112646667, states[0] = -10.949755, states[40]= 0.002794
Saving checkpoint... 
Iteration: 126276951, states[0] = -57.610070, states[40]= 0.000064
Saving checkpoint... 
Iteration: 138916009, states[0] = -94.687368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152490065, states[0] = -94.726404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166033921, states[0] = 28.549005, states[40]= 0.003447
Saving checkpoint... 
Iteration: 180083628, states[0] = 13.173669, states[40]= 0.005275
Saving checkpoint... 
Iteration: 194734422, states[0] = -38.826399, states[40]= 0.001237
Saving checkpoint... 
Iteration: 208335327, states[0] = -94.582244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223010296, states[0] = 32.473247, states[40]= 0.041936
Saving checkpoint... 
Iteration: 236666580, states[0] = -18.309802, states[40]= 0.004284
Saving checkpoint... 
Iteration: 248442087, states[0] = -94.701177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262393463, states[0] = -94.663716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276006221, states[0] = 33.985899, states[40]= 0.147490
Saving checkpoint... 
Iteration: 289923609, states[0] = -94.688846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302749815, states[0] = -44.598039, states[40]= 0.000543
Saving checkpoint... 
Iteration: 314955186, states[0] = -94.708062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328180813, states[0] = -22.507818, states[40]= 0.005331
Saving checkpoint... 
Iteration: 339745010, states[0] = -42.694766, states[40]= 0.000719
Saving checkpoint... 
Iteration: 353558330, states[0] = 21.283328, states[40]= 0.004555
Saving checkpoint... 
Iteration: 366050892, states[0] = 23.533752, states[40]= 0.004185
Saving checkpoint... 
Iteration: 380217402, states[0] = -32.993981, states[40]= 0.002569
Saving checkpoint... 
Iteration: 392329747, states[0] = -94.546555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404474040, states[0] = -94.716722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415069652, states[0] = 17.767944, states[40]= 0.004992
Saving checkpoint... 
Iteration: 428060303, states[0] = 20.681030, states[40]= 0.004644
Saving checkpoint... 
Iteration: 440681094, states[0] = -22.583783, states[40]= 0.005329
Saving checkpoint... 
Iteration: 453318294, states[0] = -93.709315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464300924, states[0] = -75.311393, states[40]= 0.000003
Saving checkpoint... 
Iteration: 477462371, states[0] = -94.711246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490643762, states[0] = -9.369453, states[40]= 0.002996
Saving checkpoint... 
Iteration: 503908283, states[0] = -94.676386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515538919, states[0] = 27.124034, states[40]= 0.003624
Saving checkpoint... 
Iteration: 529186722, states[0] = -24.129715, states[40]= 0.005196
Saving checkpoint... 
Iteration: 542632013, states[0] = -4.395826, states[40]= 0.004008
Saving checkpoint... 
Iteration: 554968438, states[0] = -94.713919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567238211, states[0] = -40.117910, states[40]= 0.001035
Saving checkpoint... 
Iteration: 581059284, states[0] = 20.992880, states[40]= 0.004599
Saving checkpoint... 
Iteration: 593965385, states[0] = -94.712427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606490893, states[0] = -94.722929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619639108, states[0] = -7.373357, states[40]= 0.003373
Saving checkpoint... 
Iteration: 632311529, states[0] = -89.758192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646215406, states[0] = -32.363556, states[40]= 0.002760
Saving checkpoint... 
Iteration: 659472749, states[0] = -94.715609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670166019, states[0] = -18.108724, states[40]= 0.004188
Saving checkpoint... 
Iteration: 682316307, states[0] = -93.086149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695651562, states[0] = -12.683241, states[40]= 0.002699
Saving checkpoint... 
Iteration: 708553463, states[0] = 22.759089, states[40]= 0.004317
Saving checkpoint... 
Iteration: 722562894, states[0] = 19.884212, states[40]= 0.004754


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396_1_r450096049_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396_1_r450096049_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 109.367449
     * GNaL_b in INaL: 0.006830
     * Gto_b in Ito: 0.072090
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009789
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.160556
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 64.833553
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037451
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 722562894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.884212 (After loading)
 - states[40]: 0.004754 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 734084772, states[0] = 12.819585, states[40]= 0.005284
Saving checkpoint... 
Iteration: 747128590, states[0] = -3.004515, states[40]= 0.004288
Saving checkpoint... 
Iteration: 760862943, states[0] = -94.627442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773229292, states[0] = -36.932176, states[40]= 0.001584
Saving checkpoint... 
Iteration: 784781851, states[0] = -59.552406, states[40]= 0.000045
Saving checkpoint... 
Iteration: 796881405, states[0] = -94.649800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809615606, states[0] = 1.989440, states[40]= 0.005007
Saving checkpoint... 
Iteration: 821870074, states[0] = -94.636473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835025311, states[0] = 30.803785, states[40]= 0.003549
Saving checkpoint... 
Iteration: 847267407, states[0] = -52.157541, states[40]= 0.000162
Saving checkpoint... 
Iteration: 860729114, states[0] = -36.870581, states[40]= 0.001597
Saving checkpoint... 
Iteration: 874218691, states[0] = -33.403579, states[40]= 0.002450
Saving checkpoint... 
Iteration: 887783648, states[0] = -60.619608, states[40]= 0.000038
Saving checkpoint... 
Iteration: 901246532, states[0] = -43.284454, states[40]= 0.000660
Saving checkpoint... 
Iteration: 914193115, states[0] = -25.875509, states[40]= 0.004846
Saving checkpoint... 
Iteration: 925714673, states[0] = -32.134442, states[40]= 0.002832
Saving checkpoint... 
Iteration: 938407619, states[0] = -94.674892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949501727, states[0] = 49.308997, states[40]= 0.253761
Saving checkpoint... 
Iteration: 960402565, states[0] = -94.670467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973310864, states[0] = -89.028441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985069145, states[0] = 17.929195, states[40]= 0.004977
Saving checkpoint... 
Iteration: 996550431, states[0] = 23.673264, states[40]= 0.004162
Saving checkpoint... 
Iteration: 1009363438, states[0] = -94.627564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020897020, states[0] = -94.665264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034031434, states[0] = 29.269078, states[40]= 0.003421
Saving checkpoint... 
Iteration: 1046775653, states[0] = -56.170952, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1059990675, states[0] = -94.721878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072305605, states[0] = -81.744736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1083269486, states[0] = -53.130890, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1094199279, states[0] = -27.586119, states[40]= 0.004351
Saving checkpoint... 
Iteration: 1106427006, states[0] = -94.689363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119366892, states[0] = -94.631824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132203172, states[0] = -28.693584, states[40]= 0.003985
Saving checkpoint... 
Iteration: 1144485298, states[0] = -94.719693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157594978, states[0] = 9.339047, states[40]= 0.005326
Saving checkpoint... 
Iteration: 1170471741, states[0] = -94.714073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183593515, states[0] = 9.843937, states[40]= 0.005327
Saving checkpoint... 
Iteration: 1196479176, states[0] = -94.717163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208689014, states[0] = -24.754199, states[40]= 0.005093
Saving checkpoint... 
Iteration: 1220501347, states[0] = 50.482149, states[40]= 0.186358
Saving checkpoint... 
Iteration: 1233915249, states[0] = -94.680449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247328737, states[0] = -94.532269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260042574, states[0] = 26.035000, states[40]= 0.003776
Saving checkpoint... 
Iteration: 1272649486, states[0] = -11.813017, states[40]= 0.002718
Saving checkpoint... 
Iteration: 1284239135, states[0] = -40.459020, states[40]= 0.000988
Saving checkpoint... 
Iteration: 1296169262, states[0] = -19.143234, states[40]= 0.004668
Saving checkpoint... 
Iteration: 1308990118, states[0] = -94.721142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320936045, states[0] = -94.694872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333349498, states[0] = -94.607047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344775174, states[0] = -55.924344, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1357275475, states[0] = -56.078524, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1368478735, states[0] = -94.716614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381834686, states[0] = -94.576174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392931719, states[0] = -94.691929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405564116, states[0] = 19.506187, states[40]= 0.004802


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396_1_r450096049_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Kr_70-conf_396_1_r450096049_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 109.367449
     * GNaL_b in INaL: 0.006830
     * Gto_b in Ito: 0.072090
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009789
     * GKs_b in IKs: 0.001883
     * GK1_b in IK1: 0.160556
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 64.833553
     * GKb_b in IKb: 0.003798
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037451
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1405564116
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.506187 (After loading)
 - states[40]: 0.004802 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1418097196, states[0] = 8.570203, states[40]= 0.005321
Saving checkpoint... 
Iteration: 1428909234, states[0] = -94.675190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441386019, states[0] = -94.653395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454887769, states[0] = -94.655194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467990350, states[0] = -94.720885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479466818, states[0] = -94.711194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492484326, states[0] = -94.718572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505746407, states[0] = -74.735075, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1517267923, states[0] = -27.092104, states[40]= 0.007517
Saving checkpoint... 
Iteration: 1528197025, states[0] = -94.683396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540648190, states[0] = -94.593450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553393389, states[0] = -94.598629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566476469, states[0] = -94.443503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576716303, states[0] = -94.520071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589160526, states[0] = -5.400335, states[40]= 0.003475
Saving checkpoint... 
Iteration: 1599665313, states[0] = -6.843860, states[40]= 0.003203
Saving checkpoint... 
Iteration: 1612231684, states[0] = -94.430553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625382125, states[0] = -39.996576, states[40]= 0.001081
Saving checkpoint... 
Iteration: 1636892574, states[0] = -94.361297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649455843, states[0] = -94.359212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660526554, states[0] = -94.238917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672388046, states[0] = -94.353354, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.228081
 - CaMKt in component CaMK (millimolar): 0.001305
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.299315
 - nass in component intracellular_ions (millimolar): 6.299388
 - ki in component intracellular_ions (millimolar): 145.629780
 - kss in component intracellular_ions (millimolar): 145.629773
 - cansr in component intracellular_ions (millimolar): 1.481494
 - cajsr in component intracellular_ions (millimolar): 1.480828
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003873
 - hf in component INa (dimensionless): 0.867808
 - hs in component INa (dimensionless): 0.867808
 - j in component INa (dimensionless): 0.867810
 - hsp in component INa (dimensionless): 0.703285
 - jp in component INa (dimensionless): 0.867811
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711051
 - hLp in component INaL (dimensionless): 0.517679
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.995603
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.998389
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997370
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002470
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003852
 - xs1 in component IKs (dimensionless): 0.037464
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997509
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:12:47 (10740): called boinc_finish(0)

</stderr_txt>
]]>


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