𝕏

Task 54770157

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_333-conf_595_1
Workunit 26006746
Created 25 Jun 2024, 10:01:29 UTC
Sent 26 Jun 2024, 5:09:16 UTC
Report deadline 29 Jun 2024, 5:09:16 UTC
Received 28 Jun 2024, 22:16:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 6 min 31 sec
CPU time 2 hours 20 min 37 sec
Validate state Valid
Credit 46.99
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_333-conf_595.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_333-conf_595_1_r905045665_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_333-conf_595_1_r905045665_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.905052
     * GNaL_b in INaL: 0.007155
     * Gto_b in Ito: 0.087273
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033882
     * GKs_b in IKs: 0.001844
     * GK1_b in IK1: 0.159717
     * Gncx_b in INaCa_i: 0.000951
     * Pnak_b in INaK: 67.575879
     * GKb_b in IKb: 0.003875
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044691
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8934979, states[0] = -51.567648, states[40]= 0.000109
Saving checkpoint... 
Iteration: 18997118, states[0] = -85.068693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 28566951, states[0] = -4.590017, states[40]= 0.000441
Saving checkpoint... 
Iteration: 37104281, states[0] = -58.907124, states[40]= 0.000032
Saving checkpoint... 
Iteration: 46209496, states[0] = 14.318898, states[40]= 0.000016
Saving checkpoint... 
Iteration: 56183937, states[0] = 27.685345, states[40]= 0.000579
Saving checkpoint... 
Iteration: 64620776, states[0] = -83.610415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74199105, states[0] = 18.861332, states[40]= 0.000004
Saving checkpoint... 
Iteration: 84180716, states[0] = 27.678654, states[40]= 0.000661
Saving checkpoint... 
Iteration: 92976760, states[0] = -85.018654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102726863, states[0] = -8.075352, states[40]= 0.000222
Saving checkpoint... 
Iteration: 112502949, states[0] = 29.214582, states[40]= 0.013880
Saving checkpoint... 
Iteration: 122167545, states[0] = 29.143502, states[40]= 0.021023
Saving checkpoint... 
Iteration: 130623923, states[0] = -84.758822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138989875, states[0] = 29.995190, states[40]= 0.654673
Saving checkpoint... 
Iteration: 146999117, states[0] = 29.183579, states[40]= 0.016009
Saving checkpoint... 
Iteration: 154811284, states[0] = -85.111545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164325732, states[0] = 28.194660, states[40]= 0.105266
Saving checkpoint... 
Iteration: 173724483, states[0] = -15.357435, states[40]= 0.000183
Saving checkpoint... 
Iteration: 183494570, states[0] = 29.112062, states[40]= 0.022445
Saving checkpoint... 
Iteration: 191400843, states[0] = -32.349120, states[40]= 0.000173
Saving checkpoint... 
Iteration: 199749069, states[0] = -54.275946, states[40]= 0.000039
Saving checkpoint... 
Iteration: 207970044, states[0] = -85.080570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216184774, states[0] = 18.765168, states[40]= 0.000004
Saving checkpoint... 
Iteration: 224984970, states[0] = 27.819211, states[40]= 0.174708
Saving checkpoint... 
Iteration: 232676373, states[0] = 22.674311, states[40]= 0.000015
Saving checkpoint... 
Iteration: 240562571, states[0] = -32.321422, states[40]= 0.000173
Saving checkpoint... 
Iteration: 248618705, states[0] = -84.893656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257568894, states[0] = -43.549131, states[40]= 0.000101
Saving checkpoint... 
Iteration: 267616732, states[0] = -84.891643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275653297, states[0] = 29.193417, states[40]= 0.013864
Saving checkpoint... 
Iteration: 283682261, states[0] = 16.093269, states[40]= 0.000006
Saving checkpoint... 
Iteration: 291270543, states[0] = -84.585590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300184250, states[0] = 13.647473, states[40]= 0.000011
Saving checkpoint... 
Iteration: 308657253, states[0] = 27.941543, states[40]= 0.000944
Saving checkpoint... 
Iteration: 318592273, states[0] = -82.798893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328305000, states[0] = 28.714099, states[40]= 0.508508
Saving checkpoint... 
Iteration: 336896409, states[0] = -46.469040, states[40]= 0.000080
Saving checkpoint... 
Iteration: 346514108, states[0] = 12.838288, states[40]= 0.000014
Saving checkpoint... 
Iteration: 354777389, states[0] = -84.927213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364334802, states[0] = 19.865621, states[40]= 0.000004
Saving checkpoint... 
Iteration: 373520039, states[0] = 6.167243, states[40]= 0.000060
Saving checkpoint... 
Iteration: 380973181, states[0] = 28.853186, states[40]= 0.041723
Saving checkpoint... 
Iteration: 388989666, states[0] = 24.964469, states[40]= 0.000072
Saving checkpoint... 
Iteration: 396407937, states[0] = -71.958445, states[40]= 0.000005
Saving checkpoint... 
Iteration: 405740995, states[0] = -72.967237, states[40]= 0.000005
Saving checkpoint... 
Iteration: 414078019, states[0] = -79.108336, states[40]= 0.000002
Saving checkpoint... 
Iteration: 423049559, states[0] = -39.672537, states[40]= 0.000130
Saving checkpoint... 
Iteration: 432613821, states[0] = -85.061320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441204091, states[0] = -24.948042, states[40]= 0.000170
Saving checkpoint... 
Iteration: 449335977, states[0] = 13.667519, states[40]= 0.000011
Saving checkpoint... 
Iteration: 458453019, states[0] = -85.149388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 466865889, states[0] = -21.521036, states[40]= 0.000165
Saving checkpoint... 
Iteration: 475774525, states[0] = -85.039392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484965400, states[0] = 29.187107, states[40]= 0.015501
Saving checkpoint... 
Iteration: 493566028, states[0] = -73.683157, states[40]= 0.000004
Saving checkpoint... 
Iteration: 502869785, states[0] = -32.463335, states[40]= 0.000172
Saving checkpoint... 
Iteration: 512738926, states[0] = -82.468046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523088194, states[0] = -84.820842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533523809, states[0] = -18.369479, states[40]= 0.000169
Saving checkpoint... 
Iteration: 542368869, states[0] = -36.746364, states[40]= 0.000151
Saving checkpoint... 
Iteration: 552136550, states[0] = 26.561788, states[40]= 0.000251
Saving checkpoint... 
Iteration: 560456153, states[0] = 29.023909, states[40]= 0.029415
Saving checkpoint... 
Iteration: 569490256, states[0] = 13.924943, states[40]= 0.000010
Saving checkpoint... 
Iteration: 577036205, states[0] = -42.504347, states[40]= 0.000108
Saving checkpoint... 
Iteration: 585100097, states[0] = -85.068907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594319249, states[0] = 15.185416, states[40]= 0.000007
Saving checkpoint... 
Iteration: 601482277, states[0] = 17.090026, states[40]= 0.000004
Saving checkpoint... 
Iteration: 610246358, states[0] = -84.819201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619784118, states[0] = 29.100846, states[40]= 0.023753
Saving checkpoint... 
Iteration: 629138598, states[0] = 21.640775, states[40]= 0.000008
Saving checkpoint... 
Iteration: 638116354, states[0] = 29.168458, states[40]= 0.017990
Saving checkpoint... 
Iteration: 646649951, states[0] = 13.411251, states[40]= 0.000012
Saving checkpoint... 
Iteration: 654492308, states[0] = 5.858177, states[40]= 0.000063
Saving checkpoint... 
Iteration: 664727061, states[0] = -83.741922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673537914, states[0] = -58.338826, states[40]= 0.000026
Saving checkpoint... 
Iteration: 683932818, states[0] = 33.981594, states[40]= 0.958624
Saving checkpoint... 
Iteration: 692837480, states[0] = -12.654802, states[40]= 0.000198
Saving checkpoint... 
Iteration: 702017792, states[0] = -34.231098, states[40]= 0.000165
Saving checkpoint... 
Iteration: 710366275, states[0] = -56.495876, states[40]= 0.000031
Saving checkpoint... 
Iteration: 717802614, states[0] = 17.950300, states[40]= 0.000004
Saving checkpoint... 
Iteration: 727209831, states[0] = -74.391736, states[40]= 0.000004
Saving checkpoint... 
Iteration: 736073964, states[0] = -84.921832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743499382, states[0] = -13.109074, states[40]= 0.000195
Saving checkpoint... 
Iteration: 752083485, states[0] = -85.058779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761377688, states[0] = -80.159459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769556052, states[0] = -84.551620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777895478, states[0] = -84.792274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787419802, states[0] = -85.124976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 796721125, states[0] = -84.610244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806917509, states[0] = -85.120302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 817816420, states[0] = -1.090986, states[40]= 0.000157
Saving checkpoint... 
Iteration: 828561145, states[0] = -84.862546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838714133, states[0] = -84.424838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847043083, states[0] = -83.936370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854257622, states[0] = 28.464342, states[40]= 0.075205
Saving checkpoint... 
Iteration: 864344183, states[0] = -47.143657, states[40]= 0.000076
Saving checkpoint... 
Iteration: 874313146, states[0] = -3.912210, states[40]= 0.000190
Saving checkpoint... 
Iteration: 882154136, states[0] = -16.087943, states[40]= 0.000178
Saving checkpoint... 
Iteration: 891549638, states[0] = -84.759282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901382771, states[0] = -84.776378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909030365, states[0] = -80.840930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 915789520, states[0] = 13.547034, states[40]= 0.000011
Saving checkpoint... 
Iteration: 923667198, states[0] = -41.071752, states[40]= 0.000119
Saving checkpoint... 
Iteration: 933127075, states[0] = 9.175739, states[40]= 0.000033
Saving checkpoint... 
Iteration: 943578464, states[0] = 27.702173, states[40]= 0.281012
Saving checkpoint... 
Iteration: 952299221, states[0] = 2.808722, states[40]= 0.000102
Saving checkpoint... 
Iteration: 960833012, states[0] = -45.032186, states[40]= 0.000090
Saving checkpoint... 
Iteration: 968933504, states[0] = 24.055485, states[40]= 0.000038
Saving checkpoint... 
Iteration: 976632543, states[0] = 0.365200, states[40]= 0.000137
Saving checkpoint... 
Iteration: 986347018, states[0] = -68.875278, states[40]= 0.000008
Saving checkpoint... 
Iteration: 994805727, states[0] = -10.295264, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1003280501, states[0] = 13.735817, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1012441231, states[0] = 17.065284, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1021644171, states[0] = -22.122935, states[40]= 0.000165
Saving checkpoint... 
Iteration: 1031282508, states[0] = 10.266816, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1040409609, states[0] = 29.184964, states[40]= 0.016959
Saving checkpoint... 
Iteration: 1049489854, states[0] = -43.702666, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1058777490, states[0] = 11.946615, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1068296567, states[0] = -7.665428, states[40]= 0.000210
Saving checkpoint... 
Iteration: 1078211065, states[0] = -84.961497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087084003, states[0] = 26.159612, states[40]= 0.000178
Saving checkpoint... 
Iteration: 1096186774, states[0] = -84.234029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105115042, states[0] = 4.880334, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1113391062, states[0] = 33.509540, states[40]= 1.043858
Saving checkpoint... 
Iteration: 1121246802, states[0] = 26.358177, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1130020064, states[0] = -84.529129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138830440, states[0] = -66.792770, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1148092425, states[0] = 18.263266, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1156992133, states[0] = -62.023913, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1165753154, states[0] = 20.766010, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1174740480, states[0] = 26.771067, states[40]= 0.000298
Saving checkpoint... 
Iteration: 1183035718, states[0] = -84.976464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1192705391, states[0] = -85.022579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199834508, states[0] = -80.710651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209744473, states[0] = 23.156103, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1218727859, states[0] = 29.110305, states[40]= 0.006050
Saving checkpoint... 
Iteration: 1227737973, states[0] = 25.533712, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1235253619, states[0] = 16.210147, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1244221338, states[0] = 29.068470, states[40]= 0.026883
Saving checkpoint... 
Iteration: 1254176190, states[0] = -84.614459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263437780, states[0] = -0.253564, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1271705082, states[0] = -85.097393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280299714, states[0] = -43.139898, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1288757342, states[0] = 9.832090, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1296931639, states[0] = 2.612342, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1305260496, states[0] = 5.937470, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1314304400, states[0] = -54.354019, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1324915196, states[0] = 13.610450, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1333040341, states[0] = 27.734386, states[40]= 0.207845
Saving checkpoint... 
Iteration: 1342004067, states[0] = -84.716156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351584183, states[0] = 9.992573, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1359822876, states[0] = -83.268163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368948141, states[0] = -29.968887, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1376893762, states[0] = 23.513449, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1385920527, states[0] = 4.680401, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1395665879, states[0] = -84.725179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1406290880, states[0] = -48.332674, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1417170269, states[0] = -84.844414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1426447476, states[0] = -37.168977, states[40]= 0.000147
Saving checkpoint... 
Iteration: 1434958280, states[0] = -53.327186, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1443010508, states[0] = -84.969092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453272354, states[0] = -28.969335, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1462254631, states[0] = -4.236993, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1472053576, states[0] = 22.069143, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1482418161, states[0] = -2.849521, states[40]= 0.000179
Saving checkpoint... 
Iteration: 1492784566, states[0] = -51.560321, states[40]= 0.000051
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.968716
 - CaMKt in component CaMK (millimolar): 0.222919
 - cass in component intracellular_ions (millimolar): 0.000174
 - nai in component intracellular_ions (millimolar): 7.405978
 - nass in component intracellular_ions (millimolar): 7.406335
 - ki in component intracellular_ions (millimolar): 143.671822
 - kss in component intracellular_ions (millimolar): 143.671784
 - cansr in component intracellular_ions (millimolar): 3.389372
 - cajsr in component intracellular_ions (millimolar): 1.938958
 - cai in component intracellular_ions (millimolar): 0.000163
 - m in component INa (dimensionless): 0.009836
 - hf in component INa (dimensionless): 0.589104
 - hs in component INa (dimensionless): 0.588058
 - j in component INa (dimensionless): 0.562981
 - hsp in component INa (dimensionless): 0.336711
 - jp in component INa (dimensionless): 0.524954
 - mL in component INaL (dimensionless): 0.000327
 - hL in component INaL (dimensionless): 0.194381
 - hLp in component INaL (dimensionless): 0.080285
 - a in component Ito (dimensionless): 0.001218
 - iF in component Ito (dimensionless): 0.999253
 - iS in component Ito (dimensionless): 0.136850
 - ap in component Ito (dimensionless): 0.000621
 - iFp in component Ito (dimensionless): 0.999254
 - iSp in component Ito (dimensionless): 0.154102
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.686919
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.933550
 - jca in component ICaL (dimensionless): 0.916093
 - ffp in component ICaL (dimensionless): 0.999209
 - fcafp in component ICaL (dimensionless): 0.999951
 - nca in component ICaL (dimensionless): 0.043822
 - xrf in component IKr (dimensionless): 0.088764
 - xrs in component IKr (dimensionless): 0.865688
 - xs1 in component IKs (dimensionless): 0.563179
 - xs2 in component IKs (dimensionless): 0.005799
 - xk1 in component IK1 (dimensionless): 0.996704
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:56:19 (8552): called boinc_finish(0)

</stderr_txt>
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