𝕏

Task 54768632

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_1000-conf_393_0
Workunit 26005989
Created 25 Jun 2024, 10:00:47 UTC
Sent 26 Jun 2024, 4:47:23 UTC
Report deadline 29 Jun 2024, 4:47:23 UTC
Received 26 Jun 2024, 11:05:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 40 min 19 sec
CPU time 1 hours 33 min 49 sec
Validate state Valid
Credit 42.30
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.90 MB
Peak swap size 4.13 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_1000-conf_393.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_1000-conf_393_0_r2059242068_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_1000-conf_393_0_r2059242068_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.756485
     * GNaL_b in INaL: 0.008042
     * Gto_b in Ito: 0.078350
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032172
     * GKs_b in IKs: 0.001773
     * GK1_b in IK1: 0.151266
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.745101
     * GKb_b in IKb: 0.003913
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037276
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12773241, states[0] = -84.242160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25037035, states[0] = 25.749148, states[40]= 0.000016
Saving checkpoint... 
Iteration: 36734444, states[0] = -83.981212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48879211, states[0] = -84.397369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61036312, states[0] = 26.223990, states[40]= 0.000015
Saving checkpoint... 
Iteration: 72918978, states[0] = -84.428304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85674104, states[0] = -81.415872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98124310, states[0] = -31.897236, states[40]= 0.000244
Saving checkpoint... 
Iteration: 110846624, states[0] = -84.337801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123643009, states[0] = -50.064732, states[40]= 0.000036
Saving checkpoint... 
Iteration: 135617076, states[0] = -24.782399, states[40]= 0.000287
Saving checkpoint... 
Iteration: 147816141, states[0] = -84.274342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160199094, states[0] = -83.709900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172899794, states[0] = -84.403781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185395542, states[0] = -84.399335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197542689, states[0] = 23.678628, states[40]= 0.000017
Saving checkpoint... 
Iteration: 210071955, states[0] = 10.059031, states[40]= 0.000152
Saving checkpoint... 
Iteration: 222338632, states[0] = -84.319959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234562465, states[0] = 14.728610, states[40]= 0.000079
Saving checkpoint... 
Iteration: 247474865, states[0] = -84.451852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259827923, states[0] = -84.298343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 272965167, states[0] = -84.447148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285895985, states[0] = -84.398209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299026131, states[0] = 29.922298, states[40]= 0.000204
Saving checkpoint... 
Iteration: 312125656, states[0] = -33.058930, states[40]= 0.000229
Saving checkpoint... 
Iteration: 324427637, states[0] = -84.424504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337046914, states[0] = 21.860558, states[40]= 0.000024
Saving checkpoint... 
Iteration: 350344615, states[0] = -84.328901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363048272, states[0] = 21.263824, states[40]= 0.000027
Saving checkpoint... 
Iteration: 375958925, states[0] = -84.442709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 389358356, states[0] = -84.350540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401611280, states[0] = -18.956494, states[40]= 0.000289
Saving checkpoint... 
Iteration: 413804605, states[0] = -84.240778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425960935, states[0] = -84.443052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437235373, states[0] = -83.958275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449960537, states[0] = -84.442536, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463026688, states[0] = 29.751919, states[40]= 0.000169
Saving checkpoint... 
Iteration: 475912203, states[0] = -84.410541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489204835, states[0] = -83.752950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502133427, states[0] = -40.555219, states[40]= 0.000116
Saving checkpoint... 
Iteration: 514501073, states[0] = 36.197164, states[40]= 0.602930
Saving checkpoint... 
Iteration: 527112199, states[0] = -19.884611, states[40]= 0.000284
Saving checkpoint... 
Iteration: 539976287, states[0] = -84.448533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553243801, states[0] = -84.003480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565763421, states[0] = -84.097249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578471699, states[0] = -84.446057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591693512, states[0] = -83.641046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604238831, states[0] = -83.975678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617455165, states[0] = -84.437559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630300466, states[0] = -84.226419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642734279, states[0] = -83.949083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656047909, states[0] = 21.425325, states[40]= 0.000026
Saving checkpoint... 
Iteration: 669081110, states[0] = 5.243562, states[40]= 0.000271
Saving checkpoint... 
Iteration: 681582118, states[0] = 4.683932, states[40]= 0.000287
Saving checkpoint... 
Iteration: 694077776, states[0] = 7.047444, states[40]= 0.000222
Saving checkpoint... 
Iteration: 706358843, states[0] = -84.347034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719374565, states[0] = -84.368382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 732446579, states[0] = -84.431279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744652367, states[0] = -59.562974, states[40]= 0.000009
Saving checkpoint... 
Iteration: 757806341, states[0] = -84.240795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770666432, states[0] = -75.363241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783195113, states[0] = -83.659087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794940897, states[0] = -84.427049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806519974, states[0] = 31.459959, states[40]= 0.001750
Saving checkpoint... 
Iteration: 818854188, states[0] = -84.338426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830957026, states[0] = -84.435700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843625542, states[0] = -32.939177, states[40]= 0.000231
Saving checkpoint... 
Iteration: 855722582, states[0] = -83.873637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868132905, states[0] = -40.042267, states[40]= 0.000122
Saving checkpoint... 
Iteration: 880773663, states[0] = -84.134501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 892688567, states[0] = -83.538985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904948257, states[0] = -84.429954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917337368, states[0] = -84.308218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930756558, states[0] = -84.061685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943544273, states[0] = 23.008134, states[40]= 0.000019
Saving checkpoint... 
Iteration: 956229707, states[0] = -83.917379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968237614, states[0] = -83.963838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980990904, states[0] = -84.448308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993423295, states[0] = -84.412448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005739137, states[0] = -83.971888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018537689, states[0] = 25.751268, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1031599432, states[0] = -7.231035, states[40]= 0.000482
Saving checkpoint... 
Iteration: 1044108896, states[0] = -16.512646, states[40]= 0.000314
Saving checkpoint... 
Iteration: 1056954361, states[0] = -84.431301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069770529, states[0] = -84.119732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082642740, states[0] = -49.703499, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1095501844, states[0] = 36.587451, states[40]= 0.950668
Saving checkpoint... 
Iteration: 1107462221, states[0] = -84.434644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1120474353, states[0] = -84.440019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133195000, states[0] = -83.652768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145688555, states[0] = -83.534862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158193348, states[0] = -83.630637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171181931, states[0] = -83.164130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183829139, states[0] = -84.288453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196847629, states[0] = -84.322732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209464613, states[0] = -84.434445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222128047, states[0] = -35.346625, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1234472574, states[0] = -84.437740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247026419, states[0] = 29.838979, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1259637982, states[0] = -44.986122, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1271375928, states[0] = -84.362723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1284178084, states[0] = -82.573229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297487437, states[0] = -84.442862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310650442, states[0] = -57.524937, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1323590678, states[0] = -0.486217, states[40]= 0.000433
Saving checkpoint... 
Iteration: 1335669430, states[0] = -78.220272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348314411, states[0] = -84.253317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360132619, states[0] = -39.755967, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1372565856, states[0] = 13.096418, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1384967857, states[0] = -84.433633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398596640, states[0] = -4.854510, states[40]= 0.000492
Saving checkpoint... 
Iteration: 1411100933, states[0] = -8.589649, states[40]= 0.000465
Saving checkpoint... 
Iteration: 1424269263, states[0] = -84.109867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437617424, states[0] = -25.057588, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1449969570, states[0] = -84.433550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1462859337, states[0] = -84.337666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474242280, states[0] = -83.982732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486859497, states[0] = -84.337582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498402521, states[0] = -84.388370, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.320352
 - CaMKt in component CaMK (millimolar): 0.017031
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 6.677391
 - nass in component intracellular_ions (millimolar): 6.677512
 - ki in component intracellular_ions (millimolar): 145.102167
 - kss in component intracellular_ions (millimolar): 145.102143
 - cansr in component intracellular_ions (millimolar): 1.816465
 - cajsr in component intracellular_ions (millimolar): 1.762341
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.010497
 - hf in component INa (dimensionless): 0.563105
 - hs in component INa (dimensionless): 0.563070
 - j in component INa (dimensionless): 0.562887
 - hsp in component INa (dimensionless): 0.317472
 - jp in component INa (dimensionless): 0.562757
 - mL in component INaL (dimensionless): 0.000370
 - hL in component INaL (dimensionless): 0.381520
 - hLp in component INaL (dimensionless): 0.180141
 - a in component Ito (dimensionless): 0.001272
 - iF in component Ito (dimensionless): 0.999169
 - iS in component Ito (dimensionless): 0.547076
 - ap in component Ito (dimensionless): 0.000648
 - iFp in component Ito (dimensionless): 0.999169
 - iSp in component Ito (dimensionless): 0.586734
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.906749
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999794
 - jca in component ICaL (dimensionless): 0.999969
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003658
 - xrf in component IKr (dimensionless): 0.000015
 - xrs in component IKr (dimensionless): 0.511668
 - xs1 in component IKs (dimensionless): 0.283632
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996843
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
06:27:40 (49571): called boinc_finish(0)

</stderr_txt>
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