𝕏

Task 54768228

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_10000-conf_493_1
Workunit 26005787
Created 25 Jun 2024, 10:00:36 UTC
Sent 26 Jun 2024, 4:45:48 UTC
Report deadline 29 Jun 2024, 4:45:48 UTC
Received 28 Jun 2024, 5:22:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 45 min 17 sec
CPU time 2 hours 18 min 59 sec
Validate state Valid
Credit 43.93
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.17 MB
Peak swap size 6.24 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_10000-conf_493.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_10000-conf_493_1_r562185735_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_10000-conf_493_1_r562185735_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.075005
     * GNaL_b in INaL: 0.006638
     * Gto_b in Ito: 0.083778
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033599
     * GKs_b in IKs: 0.001832
     * GK1_b in IK1: 0.145952
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 69.433412
     * GKb_b in IKb: 0.003898
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033587
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8414647, states[0] = -93.814864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16875252, states[0] = -93.722905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25079063, states[0] = 14.065434, states[40]= 0.002451
Saving checkpoint... 
Iteration: 33551355, states[0] = -93.620162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42347759, states[0] = -93.607940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50688267, states[0] = -93.639578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59108051, states[0] = -93.582830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67532513, states[0] = -93.587194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76076363, states[0] = -93.620026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84525586, states[0] = -93.575581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93340901, states[0] = -93.578259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102222931, states[0] = -93.586454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110427686, states[0] = -93.528306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118812338, states[0] = -93.575604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127174377, states[0] = -93.586472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135519951, states[0] = -93.593145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143524761, states[0] = -93.576226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151931153, states[0] = -93.590036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160206771, states[0] = -76.601403, states[40]= 0.000003
Saving checkpoint... 
Iteration: 168525232, states[0] = -93.576052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176911636, states[0] = -93.590252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185301647, states[0] = -93.261317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193610983, states[0] = -93.575643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201900385, states[0] = -93.590379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210264995, states[0] = -93.100525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218477424, states[0] = -93.576076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226913432, states[0] = -93.590083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235194608, states[0] = -65.276967, states[40]= 0.000023
Saving checkpoint... 
Iteration: 243568207, states[0] = -93.575690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252317792, states[0] = -93.584075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260755395, states[0] = -93.628309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269105975, states[0] = -93.574052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277140919, states[0] = -93.586324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285545212, states[0] = -93.602399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293620664, states[0] = -93.575439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301840558, states[0] = -93.591384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310080890, states[0] = 13.536643, states[40]= 0.001961
Saving checkpoint... 
Iteration: 318191406, states[0] = -93.577206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326538158, states[0] = -93.598716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335050251, states[0] = 25.008431, states[40]= 0.000398
Saving checkpoint... 
Iteration: 343682406, states[0] = -93.575175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351968424, states[0] = -93.588947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360181973, states[0] = -55.461138, states[40]= 0.000116
Saving checkpoint... 
Iteration: 368589381, states[0] = -93.575470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376998551, states[0] = -93.588410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385181752, states[0] = -55.292105, states[40]= 0.000120
Saving checkpoint... 
Iteration: 393538694, states[0] = -93.575630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401926105, states[0] = -93.589646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410405384, states[0] = -93.500608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418789344, states[0] = -93.574759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427291478, states[0] = -93.584198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435606585, states[0] = -93.617555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443691979, states[0] = -93.575043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452063123, states[0] = -93.587297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460598130, states[0] = -93.615981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469085394, states[0] = -93.573894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477794418, states[0] = -93.579434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486437906, states[0] = -93.601677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495103027, states[0] = 3.110417, states[40]= 0.003859
Saving checkpoint... 
Iteration: 503041881, states[0] = -93.577819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511123640, states[0] = -93.614203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519283491, states[0] = -93.573385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527498125, states[0] = -93.581865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535590465, states[0] = -93.614368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543987869, states[0] = -93.574070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552448472, states[0] = -93.582334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561165730, states[0] = -93.612232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569841995, states[0] = -93.572297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578524322, states[0] = -93.575500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586705843, states[0] = -93.594039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594524034, states[0] = -93.572824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602594802, states[0] = -93.580899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610632280, states[0] = -93.621238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619166574, states[0] = -93.573550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627409107, states[0] = -93.582669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635530392, states[0] = -93.596624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643851240, states[0] = -93.574350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653213157, states[0] = -93.576763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661775957, states[0] = -93.592374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670098244, states[0] = 5.617074, states[40]= 0.003523
Saving checkpoint... 
Iteration: 678550709, states[0] = -93.575302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686986537, states[0] = -93.588304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694943998, states[0] = -93.572014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702704489, states[0] = -93.579888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711481482, states[0] = -93.600049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719616114, states[0] = -93.572530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728028093, states[0] = -93.577675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736400863, states[0] = -93.602686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745002592, states[0] = 41.813771, states[40]= 0.733151
Saving checkpoint... 
Iteration: 753332267, states[0] = -93.576110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761753571, states[0] = -93.592768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770289126, states[0] = -93.211399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778523131, states[0] = -93.575306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786756040, states[0] = -93.592688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794794406, states[0] = -93.572151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803223806, states[0] = -93.576563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811586713, states[0] = -93.596858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820154634, states[0] = -34.533229, states[40]= 0.001839
Saving checkpoint... 
Iteration: 828638206, states[0] = -93.574842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837142513, states[0] = -93.585738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845225827, states[0] = -91.959671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853880566, states[0] = -93.574057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862306552, states[0] = -93.583587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870577813, states[0] = -93.611192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879278078, states[0] = -93.573039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887312938, states[0] = -93.583486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895812207, states[0] = -93.627084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904144300, states[0] = -93.573319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912527950, states[0] = -93.581199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920891012, states[0] = -93.624546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929521044, states[0] = -93.572497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937522538, states[0] = -93.581225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945978607, states[0] = -93.620659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954297567, states[0] = -93.572923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962468210, states[0] = -93.581728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970917010, states[0] = -93.623423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979212765, states[0] = -93.573086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987747977, states[0] = -93.579270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996131891, states[0] = -93.613342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004492364, states[0] = -93.572477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013432757, states[0] = -93.575426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021536289, states[0] = -93.598081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030121001, states[0] = -8.747892, states[40]= 0.002943
Saving checkpoint... 
Iteration: 1038723184, states[0] = -93.574351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046828924, states[0] = -93.590877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055320760, states[0] = -93.324827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063929745, states[0] = -93.573711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071797042, states[0] = -93.591515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080810848, states[0] = -93.626931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089140741, states[0] = -93.573144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097983001, states[0] = -93.577574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106472820, states[0] = -93.599931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114802600, states[0] = -93.571820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123383907, states[0] = -93.575520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132175609, states[0] = -93.584985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140589568, states[0] = -93.613582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148818537, states[0] = -93.573946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156823795, states[0] = -93.590873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165118094, states[0] = -6.515865, states[40]= 0.003379
Saving checkpoint... 
Iteration: 1173505258, states[0] = -93.574982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181340801, states[0] = -93.604407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190278611, states[0] = -93.165056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198622225, states[0] = -93.574530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206577295, states[0] = -93.596727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214420669, states[0] = -93.572409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222515668, states[0] = -93.581007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229927059, states[0] = -93.571509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238250764, states[0] = -93.576002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246689638, states[0] = -93.593773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255028600, states[0] = 30.880356, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1263163152, states[0] = -93.576409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271297274, states[0] = -93.605984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279342445, states[0] = -93.572505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287900096, states[0] = -93.577906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296316424, states[0] = -93.605216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303963983, states[0] = -93.573379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311217644, states[0] = -93.609213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319362525, states[0] = -93.572423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327955944, states[0] = -93.577511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336414850, states[0] = -93.601611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345188753, states[0] = -60.647660, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1353118441, states[0] = -93.576553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361404079, states[0] = -93.601956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369194664, states[0] = -93.572740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377386299, states[0] = -93.582170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383887405, states[0] = -93.573512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391675761, states[0] = -93.593968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399595875, states[0] = -93.571892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407008519, states[0] = -93.587223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414419112, states[0] = -93.572214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421968120, states[0] = -93.587891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430386813, states[0] = -93.472610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438287104, states[0] = -93.575634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446458388, states[0] = -93.600057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454884846, states[0] = -93.571351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462602379, states[0] = -93.579980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470600372, states[0] = -93.615410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478925186, states[0] = -93.573311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487048218, states[0] = -93.586504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494891723, states[0] = -93.571301, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.447119
 - CaMKt in component CaMK (millimolar): 0.001056
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.678609
 - nass in component intracellular_ions (millimolar): 6.678737
 - ki in component intracellular_ions (millimolar): 145.183511
 - kss in component intracellular_ions (millimolar): 145.183502
 - cansr in component intracellular_ions (millimolar): 1.867663
 - cajsr in component intracellular_ions (millimolar): 1.867569
 - cai in component intracellular_ions (millimolar): 0.000108
 - m in component INa (dimensionless): 0.004191
 - hf in component INa (dimensionless): 0.852380
 - hs in component INa (dimensionless): 0.852380
 - j in component INa (dimensionless): 0.852380
 - hsp in component INa (dimensionless): 0.675827
 - jp in component INa (dimensionless): 0.852381
 - mL in component INaL (dimensionless): 0.000065
 - hL in component INaL (dimensionless): 0.689142
 - hLp in component INaL (dimensionless): 0.492043
 - a in component Ito (dimensionless): 0.000688
 - iF in component Ito (dimensionless): 0.999832
 - iS in component Ito (dimensionless): 0.999828
 - ap in component Ito (dimensionless): 0.000350
 - iFp in component Ito (dimensionless): 0.999832
 - iSp in component Ito (dimensionless): 0.999832
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999991
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005975
 - xrf in component IKr (dimensionless): 0.000004
 - xrs in component IKr (dimensionless): 0.000007
 - xs1 in component IKs (dimensionless): 0.002136
 - xs2 in component IKs (dimensionless): 0.000103
 - xk1 in component IK1 (dimensionless): 0.997694
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:21:52 (9980): called boinc_finish(0)

</stderr_txt>
]]>


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