𝕏

Task 54765527

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_666-conf_389_1
Workunit 26004438
Created 25 Jun 2024, 9:59:22 UTC
Sent 26 Jun 2024, 4:28:23 UTC
Report deadline 29 Jun 2024, 4:28:27 UTC
Received 27 Jun 2024, 4:55:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217411
Run time 1 hours 15 min 4 sec
CPU time 1 hours 13 min 59 sec
Validate state Valid
Credit 41.99
Device peak FLOPS 3.22 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 6.30 MB
Peak disk usage 0.22 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_666-conf_389.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_666-conf_389_1_r74794649_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Schmidt_666-conf_389_1_r74794649_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.831930
     * GNaL_b in INaL: 0.007225
     * Gto_b in Ito: 0.089978
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032776
     * GKs_b in IKs: 0.001757
     * GK1_b in IK1: 0.156419
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 69.201552
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040154
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11517136, states[0] = -84.074511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22847248, states[0] = -83.952028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34002844, states[0] = 38.285922, states[40]= 0.670130
Saving checkpoint... 
Iteration: 45268021, states[0] = -84.480970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56562229, states[0] = -84.307549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67683983, states[0] = 31.457657, states[40]= 0.015526
Saving checkpoint... 
Iteration: 78632802, states[0] = -84.574763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89806286, states[0] = -58.177122, states[40]= 0.000013
Saving checkpoint... 
Iteration: 101143551, states[0] = -62.173975, states[40]= 0.000007
Saving checkpoint... 
Iteration: 112379761, states[0] = 23.040117, states[40]= 0.000012
Saving checkpoint... 
Iteration: 123316311, states[0] = -84.609011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134545569, states[0] = -84.182144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145598579, states[0] = -84.464515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156531329, states[0] = -84.060667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167701007, states[0] = 29.230900, states[40]= 0.000222
Saving checkpoint... 
Iteration: 179115081, states[0] = -26.411346, states[40]= 0.000239
Saving checkpoint... 
Iteration: 190253449, states[0] = -84.405509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201335080, states[0] = -84.634953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212526679, states[0] = -83.992021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223678693, states[0] = 36.518390, states[40]= 0.327231
Saving checkpoint... 
Iteration: 234894407, states[0] = -84.252401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246066486, states[0] = 16.384442, states[40]= 0.000043
Saving checkpoint... 
Iteration: 257236067, states[0] = -84.296568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268541957, states[0] = -84.100791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279892124, states[0] = -84.221874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291023199, states[0] = 30.249321, states[40]= 0.101834
Saving checkpoint... 
Iteration: 302280700, states[0] = -84.489063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313515768, states[0] = -83.655050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324596786, states[0] = -84.417152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 335778542, states[0] = -13.792945, states[40]= 0.000316
Saving checkpoint... 
Iteration: 346909521, states[0] = -84.307932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358185708, states[0] = -83.707377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369517660, states[0] = -83.597806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380650004, states[0] = -84.577742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 391613288, states[0] = -84.468422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402823471, states[0] = -60.087089, states[40]= 0.000010
Saving checkpoint... 
Iteration: 414061403, states[0] = 23.078992, states[40]= 0.000012
Saving checkpoint... 
Iteration: 425381473, states[0] = 28.912363, states[40]= 0.000162
Saving checkpoint... 
Iteration: 436733039, states[0] = 21.253261, states[40]= 0.000017
Saving checkpoint... 
Iteration: 447817605, states[0] = -50.889497, states[40]= 0.000033
Saving checkpoint... 
Iteration: 458929667, states[0] = -84.381537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470281387, states[0] = -84.457273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481605025, states[0] = -84.415443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492755930, states[0] = 10.652360, states[40]= 0.000107
Saving checkpoint... 
Iteration: 503884561, states[0] = -84.074775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515095327, states[0] = 7.721661, states[40]= 0.000160
Saving checkpoint... 
Iteration: 526363439, states[0] = 31.875015, states[40]= 0.558946
Saving checkpoint... 
Iteration: 537398598, states[0] = 24.145768, states[40]= 0.000011
Saving checkpoint... 
Iteration: 548509355, states[0] = -74.817614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559734457, states[0] = 23.496372, states[40]= 0.000012
Saving checkpoint... 
Iteration: 571008302, states[0] = -84.605900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582302994, states[0] = -84.509739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 593367990, states[0] = 30.175467, states[40]= 0.368971
Saving checkpoint... 
Iteration: 604396833, states[0] = 26.395768, states[40]= 0.000022
Saving checkpoint... 
Iteration: 615616417, states[0] = -84.432062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626917523, states[0] = -84.265733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 638059851, states[0] = 28.522354, states[40]= 0.000112
Saving checkpoint... 
Iteration: 649211590, states[0] = -83.944522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660364977, states[0] = -84.635736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671658789, states[0] = -84.557637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682817905, states[0] = -38.386989, states[40]= 0.000133
Saving checkpoint... 
Iteration: 693975925, states[0] = -84.509316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705150863, states[0] = -36.768898, states[40]= 0.000152
Saving checkpoint... 
Iteration: 716440873, states[0] = 6.396768, states[40]= 0.000189
Saving checkpoint... 
Iteration: 727808777, states[0] = -25.949960, states[40]= 0.000239
Saving checkpoint... 
Iteration: 739091710, states[0] = 16.087230, states[40]= 0.000045
Saving checkpoint... 
Iteration: 750263393, states[0] = -84.300801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761415018, states[0] = 21.700791, states[40]= 0.000016
Saving checkpoint... 
Iteration: 772606581, states[0] = -84.347607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783879489, states[0] = -83.863835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795111664, states[0] = 6.277601, states[40]= 0.000191
Saving checkpoint... 
Iteration: 806303165, states[0] = -84.468015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 817207050, states[0] = -83.607183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828351057, states[0] = -84.593384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839480854, states[0] = -25.754882, states[40]= 0.000239
Saving checkpoint... 
Iteration: 850239900, states[0] = -84.104990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857338247, states[0] = -84.561793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 868428801, states[0] = 17.500588, states[40]= 0.000035
Saving checkpoint... 
Iteration: 879284699, states[0] = -84.375328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890282579, states[0] = -84.362158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901628087, states[0] = -84.414711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 912748432, states[0] = 25.165004, states[40]= 0.000013
Saving checkpoint... 
Iteration: 923955291, states[0] = -84.381989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934990194, states[0] = -84.510639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946314294, states[0] = -84.479218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957482943, states[0] = -21.462988, states[40]= 0.000240
Saving checkpoint... 
Iteration: 968668316, states[0] = -84.537327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 979940551, states[0] = -84.289964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991044006, states[0] = -84.621959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002154665, states[0] = -24.643375, states[40]= 0.000237
Saving checkpoint... 
Iteration: 1013273741, states[0] = -84.278632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024601563, states[0] = -84.241088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035613178, states[0] = -84.306474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046689641, states[0] = -84.576904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058006297, states[0] = -84.535885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069199572, states[0] = -71.721166, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1080487121, states[0] = -19.199059, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1091679101, states[0] = -84.546435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102895117, states[0] = -83.851122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114237910, states[0] = -83.965729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125408048, states[0] = 31.200743, states[40]= 0.003127
Saving checkpoint... 
Iteration: 1136592755, states[0] = -84.138741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147542731, states[0] = -78.412649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158646355, states[0] = -84.430939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169945246, states[0] = -84.257115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178390188, states[0] = -84.623222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1183158913, states[0] = -19.187177, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1189479412, states[0] = -4.719963, states[40]= 0.000409
Saving checkpoint... 
Iteration: 1197999733, states[0] = -84.493828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1208943010, states[0] = -84.229995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215624233, states[0] = -84.314026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224770106, states[0] = 22.377910, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1231578534, states[0] = -83.977326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238308927, states[0] = -84.395760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244684181, states[0] = -84.536652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1250162491, states[0] = -19.445600, states[40]= 0.000246
Saving checkpoint... 
Iteration: 1256485077, states[0] = -6.980274, states[40]= 0.000407
Saving checkpoint... 
Iteration: 1262761075, states[0] = 27.233847, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1268935698, states[0] = -84.157934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279112932, states[0] = 19.069270, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1289726540, states[0] = -84.616850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300780301, states[0] = 19.260759, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1311952328, states[0] = -84.253539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1323040672, states[0] = -84.578886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1334215523, states[0] = -75.008500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1345384898, states[0] = -84.596920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1356695197, states[0] = -84.547568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367858939, states[0] = -45.731233, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1378995248, states[0] = -84.443405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390098654, states[0] = 28.075370, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1401222658, states[0] = -78.915333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411985288, states[0] = -84.396083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1423306832, states[0] = -84.338093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434505205, states[0] = -19.627808, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1445636683, states[0] = -84.313671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456688900, states[0] = -84.516003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467814568, states[0] = 4.612498, states[40]= 0.000230
Saving checkpoint... 
Iteration: 1479112557, states[0] = 24.057046, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1490142300, states[0] = 8.804792, states[40]= 0.000139
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.494827
 - CaMKt in component CaMK (millimolar): 0.039421
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.898620
 - nass in component intracellular_ions (millimolar): 6.898778
 - ki in component intracellular_ions (millimolar): 144.760351
 - kss in component intracellular_ions (millimolar): 144.760322
 - cansr in component intracellular_ions (millimolar): 2.083263
 - cajsr in component intracellular_ions (millimolar): 1.843620
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010315
 - hf in component INa (dimensionless): 0.570144
 - hs in component INa (dimensionless): 0.569984
 - j in component INa (dimensionless): 0.569115
 - hsp in component INa (dimensionless): 0.323350
 - jp in component INa (dimensionless): 0.568401
 - mL in component INaL (dimensionless): 0.000358
 - hL in component INaL (dimensionless): 0.344064
 - hLp in component INaL (dimensionless): 0.149588
 - a in component Ito (dimensionless): 0.001258
 - iF in component Ito (dimensionless): 0.999193
 - iS in component Ito (dimensionless): 0.365514
 - ap in component Ito (dimensionless): 0.000641
 - iFp in component Ito (dimensionless): 0.999194
 - iSp in component Ito (dimensionless): 0.399642
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.843176
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995767
 - jca in component ICaL (dimensionless): 0.998123
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006043
 - xrf in component IKr (dimensionless): 0.000415
 - xrs in component IKr (dimensionless): 0.674785
 - xs1 in component IKs (dimensionless): 0.385568
 - xs2 in component IKs (dimensionless): 0.000283
 - xk1 in component IK1 (dimensionless): 0.996803
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
06:04:27 (2152): called boinc_finish(0)

</stderr_txt>
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