𝕏

Task 54752906

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_EPI_5000-conf_475_0
Workunit 25998134
Created 25 Jun 2024, 9:53:42 UTC
Sent 26 Jun 2024, 2:41:42 UTC
Report deadline 29 Jun 2024, 2:41:42 UTC
Received 27 Jun 2024, 10:06:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214017
Run time 2 hours 47 min 45 sec
CPU time 2 hours 47 min 44 sec
Validate state Valid
Credit 47.66
Device peak FLOPS 3.52 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.60 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_EPI_5000-conf_475.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_EPI_5000-conf_475_0_r1736050145_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_EPI_5000-conf_475_0_r1736050145_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 108.609993
     * GNaL_b in INaL: 0.007697
     * Gto_b in Ito: 0.076497
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033519
     * GKs_b in IKs: 0.001924
     * GK1_b in IK1: 0.155754
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 70.049264
     * GKb_b in IKb: 0.004036
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053769
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7452858, states[0] = -94.310379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16341345, states[0] = -94.245125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28146617, states[0] = -94.224325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38608214, states[0] = -94.196947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52003684, states[0] = -94.170758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61782838, states[0] = -94.174448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75095899, states[0] = 6.358036, states[40]= 0.000040
Saving checkpoint... 
Iteration: 83726522, states[0] = -94.192753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93701005, states[0] = -94.195744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96866777, states[0] = -94.180092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106197812, states[0] = -94.198072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116117973, states[0] = -94.202456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125971493, states[0] = -94.209675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135420300, states[0] = -94.166776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144457689, states[0] = -94.184253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157809724, states[0] = -94.013774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166627103, states[0] = -94.191043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174075200, states[0] = -94.192375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182179171, states[0] = -94.182727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189460586, states[0] = -94.185647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196846212, states[0] = -94.187491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204137018, states[0] = -94.191433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216760740, states[0] = -94.189066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228856843, states[0] = -94.198462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238026865, states[0] = -94.211548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247405264, states[0] = -94.180670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257382042, states[0] = -94.180837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264681083, states[0] = -94.182859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271961393, states[0] = -94.185638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279312479, states[0] = -94.187933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286618429, states[0] = -94.191602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293942826, states[0] = -94.195737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301252707, states[0] = -94.201350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308554388, states[0] = -94.208728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315838478, states[0] = -94.218036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323286855, states[0] = -94.219985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330728192, states[0] = -94.221652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338107050, states[0] = -94.220389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346924095, states[0] = -94.185629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360307379, states[0] = -94.007976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368480759, states[0] = -94.211391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377443397, states[0] = -94.179395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389191274, states[0] = -94.189295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396871948, states[0] = -94.186025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404269761, states[0] = -94.187694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411822515, states[0] = -94.186712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419169864, states[0] = -94.189470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427973206, states[0] = -94.195131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435399551, states[0] = -94.151250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444944647, states[0] = -94.178819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458238581, states[0] = -94.220354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469985988, states[0] = -94.178258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483349835, states[0] = -94.216176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493900800, states[0] = -94.195239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501231669, states[0] = -94.200415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508569091, states[0] = -94.206469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517325979, states[0] = -94.179300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530663532, states[0] = -94.220524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544048612, states[0] = -94.191047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557445886, states[0] = -94.177860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569205689, states[0] = -94.187499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576504727, states[0] = -94.191823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587926230, states[0] = -94.170172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601276920, states[0] = -94.198064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612943084, states[0] = -94.179918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624491816, states[0] = -94.182316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635477309, states[0] = -94.194906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642810121, states[0] = -94.012475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650167811, states[0] = -69.247570, states[40]= 0.000004
Saving checkpoint... 
Iteration: 657470737, states[0] = -94.176804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664852135, states[0] = -94.177803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672148203, states[0] = -94.179904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679980470, states[0] = -94.176532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693369455, states[0] = -94.213570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705122486, states[0] = -16.550976, states[40]= 0.000147
Saving checkpoint... 
Iteration: 716682981, states[0] = -94.186701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729577839, states[0] = -94.180282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741851186, states[0] = -94.183454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750876582, states[0] = -94.212777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762511691, states[0] = 22.343411, states[40]= 0.000004
Saving checkpoint... 
Iteration: 771484009, states[0] = -94.190695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784835909, states[0] = -94.176946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798221861, states[0] = -94.217870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808405093, states[0] = -94.211040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815848522, states[0] = -94.213436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823137945, states[0] = -94.217617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830386976, states[0] = -94.136060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837646297, states[0] = -43.217556, states[40]= 0.000112
Saving checkpoint... 
Iteration: 844926040, states[0] = -94.175607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853128786, states[0] = -94.217078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861317371, states[0] = -94.194592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868858585, states[0] = -94.193288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878092862, states[0] = -94.214927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885441200, states[0] = -94.176602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892788260, states[0] = -93.948471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900206285, states[0] = -93.508452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907585857, states[0] = 11.481933, states[40]= 0.000014
Saving checkpoint... 
Iteration: 914883360, states[0] = -94.175401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922172828, states[0] = -94.177508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931180752, states[0] = -94.198592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944579005, states[0] = -94.178453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954635770, states[0] = -94.177669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967205284, states[0] = -94.176762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980491428, states[0] = -94.196706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993775221, states[0] = -94.194812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004753534, states[0] = -94.175923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012213568, states[0] = -94.176290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022149807, states[0] = -94.176932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029848048, states[0] = -94.174762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037137177, states[0] = -94.176956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044504934, states[0] = -94.178591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052043714, states[0] = -94.178004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059330186, states[0] = -94.181124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066680478, states[0] = -94.183799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074375818, states[0] = -94.180252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081757463, states[0] = -94.182206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089166415, states[0] = -94.183892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096466270, states[0] = -94.188407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103772490, states[0] = -94.193975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111287834, states[0] = -94.193415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118845172, states[0] = -94.191578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126208517, states[0] = -94.195955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133540724, states[0] = -94.202385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140983853, states[0] = -94.204761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148334527, states[0] = -94.211224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155739871, states[0] = -94.214459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163159479, states[0] = -94.215169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170525338, states[0] = -94.203610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179666716, states[0] = -94.175406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193081764, states[0] = -94.211363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206499183, states[0] = -94.186649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216392656, states[0] = -94.189379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223813038, states[0] = -94.191672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231096737, states[0] = -94.199270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238375354, states[0] = -94.208730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245698437, states[0] = -94.214464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253056151, states[0] = -94.208018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260814509, states[0] = -94.211084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268290036, states[0] = -94.211946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275698400, states[0] = -94.214212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283239887, states[0] = -94.213386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290762404, states[0] = -94.212687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298094761, states[0] = -94.211537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305534560, states[0] = -94.204227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312880537, states[0] = -94.125224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321090372, states[0] = -94.198767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328461272, states[0] = -94.204175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335968430, states[0] = -94.203797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344875398, states[0] = -94.171846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352397346, states[0] = -94.171580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359843553, states[0] = -94.172020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367189754, states[0] = -94.173560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377370579, states[0] = -94.171616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384917326, states[0] = -94.171126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392276540, states[0] = -94.172413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399612185, states[0] = -94.174200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406979938, states[0] = -94.175882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414318308, states[0] = -94.178331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421747768, states[0] = -94.179516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430909729, states[0] = -94.205598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439475192, states[0] = -94.175676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446811859, states[0] = -94.178166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454112382, states[0] = -94.181945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466037261, states[0] = -94.199732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473718133, states[0] = -94.192691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481067904, states[0] = -94.198331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490338798, states[0] = -94.065401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497678832, states[0] = -86.005044, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.045425
 - CaMKt in component CaMK (millimolar): 0.001642
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.066239
 - nass in component intracellular_ions (millimolar): 7.066369
 - ki in component intracellular_ions (millimolar): 144.651507
 - kss in component intracellular_ions (millimolar): 144.651493
 - cansr in component intracellular_ions (millimolar): 2.343046
 - cajsr in component intracellular_ions (millimolar): 2.343273
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.003945
 - hf in component INa (dimensionless): 0.864327
 - hs in component INa (dimensionless): 0.864327
 - j in component INa (dimensionless): 0.864329
 - hsp in component INa (dimensionless): 0.696984
 - jp in component INa (dimensionless): 0.864330
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706017
 - hLp in component INaL (dimensionless): 0.512012
 - a in component Ito (dimensionless): 0.000661
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998821
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004917
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001797
 - xs1 in component IKs (dimensionless): 0.023056
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997553
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:05:41 (7718): called boinc_finish(0)

</stderr_txt>
]]>


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