𝕏

Task 54727193

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_40_1
Workunit 25985285
Created 25 Jun 2024, 9:42:02 UTC
Sent 25 Jun 2024, 23:06:14 UTC
Report deadline 29 Jun 2024, 8:42:14 UTC
Received 29 Jun 2024, 7:54:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 49 min 40 sec
CPU time 2 hours 24 min 33 sec
Validate state Valid
Credit 58.05
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.30 MB
Peak swap size 5.42 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_40.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_40_1_r1545462762_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_40_1_r1545462762_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.104453
     * GNaL_b in INaL: 0.007466
     * Gto_b in Ito: 0.067772
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032623
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.160645
     * Gncx_b in INaCa_i: 0.000946
     * Pnak_b in INaK: 63.947588
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034425
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11601466, states[0] = -21.808843, states[40]= 0.000872
Saving checkpoint... 
Iteration: 24479205, states[0] = -94.993797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37789949, states[0] = -94.910658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51223374, states[0] = -94.823550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64722016, states[0] = -94.817354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78166920, states[0] = -93.816399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91627854, states[0] = -45.742232, states[40]= 0.000061
Saving checkpoint... 
Iteration: 105192714, states[0] = -94.756622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118719379, states[0] = -94.806618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132137134, states[0] = -55.893901, states[40]= 0.000012
Saving checkpoint... 
Iteration: 145052082, states[0] = 11.717111, states[40]= 0.005240
Saving checkpoint... 
Iteration: 158638067, states[0] = -56.922818, states[40]= 0.000010
Saving checkpoint... 
Iteration: 172150760, states[0] = -73.373474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185593891, states[0] = -12.876621, states[40]= 0.001848
Saving checkpoint... 
Iteration: 199065078, states[0] = 6.050632, states[40]= 0.004988
Saving checkpoint... 
Iteration: 212200336, states[0] = -94.769741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223355691, states[0] = -94.934170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236869842, states[0] = -94.940045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248954199, states[0] = -94.962690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262386805, states[0] = -94.946110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275836316, states[0] = -94.924552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289194543, states[0] = -94.757912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302384338, states[0] = -94.945237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315713859, states[0] = -94.795106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329079107, states[0] = -1.415073, states[40]= 0.004192
Saving checkpoint... 
Iteration: 342001670, states[0] = 47.588164, states[40]= 0.078093
Saving checkpoint... 
Iteration: 355354991, states[0] = -94.933690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368761205, states[0] = -94.864228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381648212, states[0] = -69.585825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394997290, states[0] = -94.968768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408450585, states[0] = -94.961904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421933313, states[0] = -94.958481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435185795, states[0] = -94.737322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448636747, states[0] = -55.356932, states[40]= 0.000013
Saving checkpoint... 
Iteration: 462182767, states[0] = -94.726505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475650219, states[0] = -72.507668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489070258, states[0] = 3.532954, states[40]= 0.004805
Saving checkpoint... 
Iteration: 502593070, states[0] = -12.120894, states[40]= 0.001984
Saving checkpoint... 
Iteration: 516104680, states[0] = -22.924189, states[40]= 0.000850
Saving checkpoint... 
Iteration: 529572050, states[0] = 2.607559, states[40]= 0.004719
Saving checkpoint... 
Iteration: 542999469, states[0] = -94.968925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556464898, states[0] = -94.964246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569570074, states[0] = 3.626259, states[40]= 0.004814
Saving checkpoint... 
Iteration: 582981189, states[0] = -94.966625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596398327, states[0] = -94.949497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609848235, states[0] = -94.930389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623249953, states[0] = -94.850407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636748042, states[0] = -94.847919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650139700, states[0] = -58.785299, states[40]= 0.000007
Saving checkpoint... 
Iteration: 663011560, states[0] = 25.238506, states[40]= 0.036458
Saving checkpoint... 
Iteration: 676295535, states[0] = -94.897219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689673051, states[0] = -94.558747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703110957, states[0] = -28.811395, states[40]= 0.000567
Saving checkpoint... 
Iteration: 716574744, states[0] = 1.151397, states[40]= 0.004559
Saving checkpoint... 
Iteration: 730104255, states[0] = -22.526068, states[40]= 0.000870
Saving checkpoint... 
Iteration: 743613588, states[0] = -31.296052, states[40]= 0.000443
Saving checkpoint... 
Iteration: 756880601, states[0] = -94.943651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770466093, states[0] = -94.964301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784073040, states[0] = 2.082214, states[40]= 0.004665
Saving checkpoint... 
Iteration: 797697553, states[0] = -94.763712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811243605, states[0] = -94.841867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824605574, states[0] = -23.761126, states[40]= 0.000811
Saving checkpoint... 
Iteration: 838209780, states[0] = -94.787316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851769417, states[0] = -94.872949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864801676, states[0] = -94.901911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878349592, states[0] = -94.930868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891870873, states[0] = -94.939978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905471364, states[0] = -94.965024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919089177, states[0] = -8.733741, states[40]= 0.002681
Saving checkpoint... 
Iteration: 932221963, states[0] = -94.808821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945486420, states[0] = -94.967091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956759865, states[0] = -94.862312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970197471, states[0] = -94.763438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983643890, states[0] = -63.862397, states[40]= 0.000003
Saving checkpoint... 
Iteration: 996939008, states[0] = -94.959309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010367329, states[0] = -94.938511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024116970, states[0] = -34.520466, states[40]= 0.000302
Saving checkpoint... 
Iteration: 1037580059, states[0] = -2.016053, states[40]= 0.004091
Saving checkpoint... 
Iteration: 1051432153, states[0] = -94.957838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064512092, states[0] = 25.072527, states[40]= 0.032553
Saving checkpoint... 
Iteration: 1078318826, states[0] = -94.913746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092159731, states[0] = -88.043705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106057094, states[0] = 9.622766, states[40]= 0.005157
Saving checkpoint... 
Iteration: 1119200295, states[0] = -94.768971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129601694, states[0] = -20.125509, states[40]= 0.001004
Saving checkpoint... 
Iteration: 1139727375, states[0] = -94.817576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152264420, states[0] = -94.867359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165550080, states[0] = 12.553176, states[40]= 0.005275
Saving checkpoint... 
Iteration: 1179329333, states[0] = -94.920072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193023418, states[0] = 22.160737, states[40]= 0.008125
Saving checkpoint... 
Iteration: 1206881767, states[0] = -94.943778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220672190, states[0] = -94.509273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232643814, states[0] = -63.766808, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1246457497, states[0] = -94.962597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260352878, states[0] = -94.932162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274170597, states[0] = -94.377788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287469667, states[0] = -94.964529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301001144, states[0] = 48.461381, states[40]= 0.041881
Saving checkpoint... 
Iteration: 1314836620, states[0] = -94.924046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328693859, states[0] = -94.755822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342513959, states[0] = 24.563854, states[40]= 0.022538
Saving checkpoint... 
Iteration: 1356171870, states[0] = -94.487496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369915792, states[0] = -94.953808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383198909, states[0] = -94.766056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396696783, states[0] = -94.761780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410363437, states[0] = -94.936677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424061493, states[0] = 7.695651, states[40]= 0.005075
Saving checkpoint... 
Iteration: 1437904795, states[0] = -94.950839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451716425, states[0] = -94.798954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465506379, states[0] = 28.794961, states[40]= 0.114890
Saving checkpoint... 
Iteration: 1479030760, states[0] = 19.876580, states[40]= 0.006384
Saving checkpoint... 
Iteration: 1492793052, states[0] = -94.894675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506146193, states[0] = -93.316392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519946753, states[0] = -93.982336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533691235, states[0] = -25.443370, states[40]= 0.000729
Saving checkpoint... 
Iteration: 1547241128, states[0] = -91.542178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560993871, states[0] = -29.030199, states[40]= 0.000543
Saving checkpoint... 
Iteration: 1574755225, states[0] = 5.538590, states[40]= 0.005638
Saving checkpoint... 
Iteration: 1587941720, states[0] = 12.811181, states[40]= 0.006328
Saving checkpoint... 
Iteration: 1601615271, states[0] = -95.161356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615344911, states[0] = -94.136081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629069178, states[0] = -4.156022, states[40]= 0.004145
Saving checkpoint... 
Iteration: 1642843028, states[0] = 12.083423, states[40]= 0.006250
Saving checkpoint... 
Iteration: 1656629223, states[0] = 18.701985, states[40]= 0.007655
Saving checkpoint... 
Iteration: 1669776962, states[0] = -95.235245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683038630, states[0] = 14.292774, states[40]= 0.006542
Saving checkpoint... 
Iteration: 1693606360, states[0] = -43.403983, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1706326655, states[0] = -95.181317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718567913, states[0] = -95.066353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731243415, states[0] = -95.202816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744918474, states[0] = -58.416622, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1758322294, states[0] = 21.564503, states[40]= 0.009883
Saving checkpoint... 
Iteration: 1772109644, states[0] = 26.558217, states[40]= 0.055924
Saving checkpoint... 
Iteration: 1785622229, states[0] = 21.589562, states[40]= 0.009919
Saving checkpoint... 
Iteration: 1799395741, states[0] = -95.249237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813167318, states[0] = -94.433303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826972041, states[0] = -94.996078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840100491, states[0] = -20.244867, states[40]= 0.000999
Saving checkpoint... 
Iteration: 1853433489, states[0] = -94.972524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867164130, states[0] = -92.901030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880906297, states[0] = -94.957737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894742742, states[0] = -94.844600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908453697, states[0] = -94.964572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922203310, states[0] = -94.776423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935841225, states[0] = -94.927448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949539898, states[0] = 16.565197, states[40]= 0.005600
Saving checkpoint... 
Iteration: 1963308616, states[0] = -94.906913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977068670, states[0] = 4.317734, states[40]= 0.004870
Saving checkpoint... 
Iteration: 1989533661, states[0] = 18.870552, states[40]= 0.006049
Saving checkpoint... 
Iteration: 2003283367, states[0] = -94.886079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017084901, states[0] = -5.361379, states[40]= 0.003430
Saving checkpoint... 
Iteration: 2030320865, states[0] = -94.914482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044053348, states[0] = 11.204984, states[40]= 0.005218
Saving checkpoint... 
Iteration: 2057853219, states[0] = -94.931805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071573602, states[0] = 1.778598, states[40]= 0.004632
Saving checkpoint... 
Iteration: 2085385240, states[0] = -94.944380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099097121, states[0] = -15.841755, states[40]= 0.001402
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.843844
 - CaMKt in component CaMK (millimolar): 0.007125
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.781884
 - nass in component intracellular_ions (millimolar): 6.781944
 - ki in component intracellular_ions (millimolar): 145.192269
 - kss in component intracellular_ions (millimolar): 145.192249
 - cansr in component intracellular_ions (millimolar): 1.328838
 - cajsr in component intracellular_ions (millimolar): 1.290824
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003640
 - hf in component INa (dimensionless): 0.878991
 - hs in component INa (dimensionless): 0.878986
 - j in component INa (dimensionless): 0.878957
 - hsp in component INa (dimensionless): 0.723930
 - jp in component INa (dimensionless): 0.878938
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708325
 - hLp in component INaL (dimensionless): 0.450087
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.619986
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.693950
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931070
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999874
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001687
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344597
 - xs1 in component IKs (dimensionless): 0.245569
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997352
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:53:43 (16704): called boinc_finish(0)

</stderr_txt>
]]>


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