𝕏

Task 54709298

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_917_1
Workunit 25976343
Created 25 Jun 2024, 9:33:50 UTC
Sent 25 Jun 2024, 20:31:22 UTC
Report deadline 29 Jun 2024, 6:07:22 UTC
Received 29 Jun 2024, 2:22:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 51 min 17 sec
CPU time 2 hours 26 min 21 sec
Validate state Valid
Credit 58.39
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.35 MB
Peak swap size 5.43 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_917.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_917_1_r334619294_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_917_1_r334619294_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.550919
     * GNaL_b in INaL: 0.005905
     * Gto_b in Ito: 0.067845
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033655
     * GKs_b in IKs: 0.001892
     * GK1_b in IK1: 0.151164
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 68.019761
     * GKb_b in IKb: 0.003937
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039180
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11713246, states[0] = -94.896886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25165076, states[0] = -94.689461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37910446, states[0] = -94.992657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51367691, states[0] = -94.966768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64825332, states[0] = -94.938478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78207017, states[0] = -94.800602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91704280, states[0] = -94.791725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105214968, states[0] = -94.808953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118618091, states[0] = -44.442932, states[40]= 0.000062
Saving checkpoint... 
Iteration: 132123063, states[0] = -49.893684, states[40]= 0.000026
Saving checkpoint... 
Iteration: 145644552, states[0] = -76.942320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159091606, states[0] = -17.103643, states[40]= 0.001242
Saving checkpoint... 
Iteration: 172582325, states[0] = -8.229457, states[40]= 0.002806
Saving checkpoint... 
Iteration: 185926220, states[0] = -94.960391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199411064, states[0] = -94.956575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212571456, states[0] = -0.276930, states[40]= 0.004376
Saving checkpoint... 
Iteration: 226102996, states[0] = -28.566132, states[40]= 0.000502
Saving checkpoint... 
Iteration: 239608731, states[0] = -34.395435, states[40]= 0.000261
Saving checkpoint... 
Iteration: 252958988, states[0] = -94.966254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266386374, states[0] = -94.949073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279808067, states[0] = -94.911026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293209866, states[0] = -94.794542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306682286, states[0] = -94.737747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319831288, states[0] = -94.925391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333198747, states[0] = -94.773148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346425650, states[0] = -94.959693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359554603, states[0] = 8.405717, states[40]= 0.005162
Saving checkpoint... 
Iteration: 372824615, states[0] = -94.921546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386351050, states[0] = -94.935283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399598847, states[0] = -24.360596, states[40]= 0.000707
Saving checkpoint... 
Iteration: 413124898, states[0] = -51.812563, states[40]= 0.000019
Saving checkpoint... 
Iteration: 426559843, states[0] = 5.947844, states[40]= 0.005008
Saving checkpoint... 
Iteration: 440058219, states[0] = 6.724692, states[40]= 0.005059
Saving checkpoint... 
Iteration: 453492652, states[0] = -94.970812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467032572, states[0] = 17.705152, states[40]= 0.006441
Saving checkpoint... 
Iteration: 480227184, states[0] = -94.823964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491841632, states[0] = -94.930730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505312347, states[0] = -94.913787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518801486, states[0] = -94.906148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532205690, states[0] = -94.786585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544168317, states[0] = -94.633352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557419915, states[0] = -94.958254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569160315, states[0] = -93.926179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581057586, states[0] = 7.023549, states[40]= 0.005078
Saving checkpoint... 
Iteration: 594410052, states[0] = -94.955778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607848695, states[0] = -94.934083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621295422, states[0] = -94.901461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634763646, states[0] = -94.871921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648197622, states[0] = -94.770723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661658604, states[0] = -93.453276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674571651, states[0] = -0.389587, states[40]= 0.004359
Saving checkpoint... 
Iteration: 687961680, states[0] = -94.966399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701357201, states[0] = -94.937848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714434270, states[0] = -94.961368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727855842, states[0] = -94.937246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741325611, states[0] = -94.921942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754231240, states[0] = -94.830077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767727400, states[0] = -94.824156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781205252, states[0] = -94.785624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794634507, states[0] = -63.002037, states[40]= 0.000003
Saving checkpoint... 
Iteration: 808001272, states[0] = 49.893800, states[40]= 0.039869
Saving checkpoint... 
Iteration: 821484435, states[0] = -94.969609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834937006, states[0] = -94.961868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848384241, states[0] = -94.948027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861894991, states[0] = -94.951421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875366122, states[0] = -94.941438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888838784, states[0] = -94.929086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902226012, states[0] = -94.821896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915660987, states[0] = -94.060193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929169807, states[0] = -94.663075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942305119, states[0] = -94.908579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955762881, states[0] = -94.870922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969093541, states[0] = -18.997866, states[40]= 0.001053
Saving checkpoint... 
Iteration: 982462729, states[0] = -94.966417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994012740, states[0] = 24.110419, states[40]= 0.030070
Saving checkpoint... 
Iteration: 1007491899, states[0] = -94.970442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020945567, states[0] = -94.963439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034081530, states[0] = -7.517211, states[40]= 0.002964
Saving checkpoint... 
Iteration: 1046910960, states[0] = -94.955785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059684301, states[0] = -94.742192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072760349, states[0] = -94.868050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085963662, states[0] = -94.966512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099331480, states[0] = -94.925091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112696176, states[0] = -94.767560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126077230, states[0] = -4.121811, states[40]= 0.003699
Saving checkpoint... 
Iteration: 1139615646, states[0] = -41.591622, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1152837785, states[0] = -94.928437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166219438, states[0] = -94.810976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179709595, states[0] = -94.793568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193194014, states[0] = -94.763092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206665274, states[0] = -94.518258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220134451, states[0] = -62.933531, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1233614328, states[0] = -40.193126, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1247045943, states[0] = 12.237737, states[40]= 0.005432
Saving checkpoint... 
Iteration: 1259323589, states[0] = -94.920487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272744027, states[0] = -94.847956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286089575, states[0] = -15.018170, states[40]= 0.001511
Saving checkpoint... 
Iteration: 1297598025, states[0] = -23.529318, states[40]= 0.000750
Saving checkpoint... 
Iteration: 1310092327, states[0] = -17.773291, states[40]= 0.001169
Saving checkpoint... 
Iteration: 1322899878, states[0] = -94.952624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336140094, states[0] = -70.195397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349587876, states[0] = -13.345442, states[40]= 0.001775
Saving checkpoint... 
Iteration: 1363051349, states[0] = 9.873041, states[40]= 0.005252
Saving checkpoint... 
Iteration: 1376454652, states[0] = -94.964886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389807081, states[0] = -94.909742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403173430, states[0] = -94.702590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416531841, states[0] = 17.981573, states[40]= 0.006542
Saving checkpoint... 
Iteration: 1428721219, states[0] = -94.813830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441928708, states[0] = -94.959814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454226483, states[0] = -94.822362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466544636, states[0] = 12.797782, states[40]= 0.005486
Saving checkpoint... 
Iteration: 1479300578, states[0] = -94.904985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492738422, states[0] = -94.840177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506108525, states[0] = -50.742466, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1519426586, states[0] = -95.167513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532809062, states[0] = -53.578146, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1546202913, states[0] = 41.252529, states[40]= 0.085760
Saving checkpoint... 
Iteration: 1558673097, states[0] = -95.098320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572057117, states[0] = 1.788576, states[40]= 0.005189
Saving checkpoint... 
Iteration: 1585463317, states[0] = -95.246012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598804790, states[0] = -49.715290, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1612219371, states[0] = 21.669753, states[40]= 0.013091
Saving checkpoint... 
Iteration: 1625490518, states[0] = -32.728284, states[40]= 0.000322
Saving checkpoint... 
Iteration: 1638896976, states[0] = -95.276411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651736216, states[0] = -95.222020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664956740, states[0] = -95.244827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678376350, states[0] = -95.118746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691552629, states[0] = -95.044774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703931428, states[0] = -95.216491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717284642, states[0] = -26.018231, states[40]= 0.000635
Saving checkpoint... 
Iteration: 1730686395, states[0] = -95.270125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743916344, states[0] = 22.864135, states[40]= 0.018119
Saving checkpoint... 
Iteration: 1756912588, states[0] = -59.926355, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1769962114, states[0] = -95.250310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782861572, states[0] = -95.249803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796073972, states[0] = -95.260624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809342586, states[0] = -94.985967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822726906, states[0] = -94.862425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835888157, states[0] = -94.976111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848858480, states[0] = -94.956586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861967650, states[0] = -94.979537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872710272, states[0] = -94.804038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886009068, states[0] = 25.753000, states[40]= 0.064401
Saving checkpoint... 
Iteration: 1899378584, states[0] = -94.949876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912823386, states[0] = -94.922959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926183569, states[0] = -94.742040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939564595, states[0] = 3.541066, states[40]= 0.004822
Saving checkpoint... 
Iteration: 1952850356, states[0] = -94.935067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965717847, states[0] = -94.808478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979116949, states[0] = -43.015948, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1992533531, states[0] = 17.334910, states[40]= 0.006319
Saving checkpoint... 
Iteration: 2005960352, states[0] = -94.965682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017181750, states[0] = -94.735613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029779354, states[0] = -94.887067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043074678, states[0] = -2.332227, states[40]= 0.004042
Saving checkpoint... 
Iteration: 2056594901, states[0] = -20.373812, states[40]= 0.000943
Saving checkpoint... 
Iteration: 2070144123, states[0] = -76.107967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083213869, states[0] = -94.800830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096521571, states[0] = 21.491272, states[40]= 0.009776
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.846673
 - CaMKt in component CaMK (millimolar): 0.006457
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.621017
 - nass in component intracellular_ions (millimolar): 6.621076
 - ki in component intracellular_ions (millimolar): 145.362629
 - kss in component intracellular_ions (millimolar): 145.362609
 - cansr in component intracellular_ions (millimolar): 1.290078
 - cajsr in component intracellular_ions (millimolar): 1.253491
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003639
 - hf in component INa (dimensionless): 0.879040
 - hs in component INa (dimensionless): 0.879036
 - j in component INa (dimensionless): 0.879008
 - hsp in component INa (dimensionless): 0.724023
 - jp in component INa (dimensionless): 0.878989
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710234
 - hLp in component INaL (dimensionless): 0.455729
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.628929
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.704847
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938436
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001538
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334834
 - xs1 in component IKs (dimensionless): 0.229821
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997352
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:22:06 (7912): called boinc_finish(0)

</stderr_txt>
]]>


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