𝕏

Task 54709283

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_217_0
Workunit 25976336
Created 25 Jun 2024, 9:33:50 UTC
Sent 25 Jun 2024, 20:31:22 UTC
Report deadline 29 Jun 2024, 6:07:22 UTC
Received 29 Jun 2024, 3:44:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 51 min 7 sec
CPU time 2 hours 26 min 12 sec
Validate state Valid
Credit 59.55
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.34 MB
Peak swap size 5.42 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_217.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_217_0_r1493862671_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pueyo_APDR-conf_217_0_r1493862671_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 111.809299
     * GNaL_b in INaL: 0.006026
     * Gto_b in Ito: 0.067310
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032491
     * GKs_b in IKs: 0.001848
     * GK1_b in IK1: 0.144415
     * Gncx_b in INaCa_i: 0.000952
     * Pnak_b in INaK: 69.226802
     * GKb_b in IKb: 0.004024
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034507
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11751688, states[0] = -94.970141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25160361, states[0] = -94.018684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38621650, states[0] = -47.943501, states[40]= 0.000038
Saving checkpoint... 
Iteration: 51797403, states[0] = -94.932684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64773392, states[0] = -94.900517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77649581, states[0] = -80.678873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90708058, states[0] = -94.791641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103855527, states[0] = -94.946208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117308052, states[0] = -94.915639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130531427, states[0] = 18.542887, states[40]= 0.006644
Saving checkpoint... 
Iteration: 143999133, states[0] = -94.978843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157445685, states[0] = -94.969731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170714292, states[0] = -94.795052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184101224, states[0] = -24.698156, states[40]= 0.000715
Saving checkpoint... 
Iteration: 197545344, states[0] = 13.023311, states[40]= 0.005506
Saving checkpoint... 
Iteration: 211044550, states[0] = 13.358808, states[40]= 0.005539
Saving checkpoint... 
Iteration: 224554367, states[0] = 9.123938, states[40]= 0.005226
Saving checkpoint... 
Iteration: 238088685, states[0] = -12.404860, states[40]= 0.001947
Saving checkpoint... 
Iteration: 251540972, states[0] = 14.845218, states[40]= 0.005722
Saving checkpoint... 
Iteration: 264245442, states[0] = -94.845623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277291758, states[0] = -94.897887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290664953, states[0] = -94.022151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304042782, states[0] = 14.099898, states[40]= 0.005622
Saving checkpoint... 
Iteration: 314950835, states[0] = -94.969289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327557925, states[0] = 7.516213, states[40]= 0.005132
Saving checkpoint... 
Iteration: 340883605, states[0] = -94.951242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354250112, states[0] = -94.851973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367728950, states[0] = -94.820128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381165396, states[0] = -94.098256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394564288, states[0] = 4.473625, states[40]= 0.004924
Saving checkpoint... 
Iteration: 407966967, states[0] = -94.972101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421273734, states[0] = -94.880286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434676370, states[0] = -94.685358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446658266, states[0] = -91.002871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460160794, states[0] = -92.686069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472038516, states[0] = 15.842052, states[40]= 0.005886
Saving checkpoint... 
Iteration: 484434518, states[0] = -94.965795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497367309, states[0] = -94.944777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510838786, states[0] = -94.930920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524236080, states[0] = -94.831522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537605886, states[0] = -29.264696, states[40]= 0.000493
Saving checkpoint... 
Iteration: 551018583, states[0] = 22.767139, states[40]= 0.012674
Saving checkpoint... 
Iteration: 563748867, states[0] = -94.850166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576940957, states[0] = -94.967147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590437144, states[0] = -94.966321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603964775, states[0] = -94.971633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617422717, states[0] = -94.962928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630884200, states[0] = -94.951298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644293135, states[0] = -94.898858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657820423, states[0] = -94.919675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670744931, states[0] = -94.844617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684126090, states[0] = -50.131426, states[40]= 0.000027
Saving checkpoint... 
Iteration: 697587551, states[0] = -11.339346, states[40]= 0.002150
Saving checkpoint... 
Iteration: 710986187, states[0] = -94.974836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723520127, states[0] = 22.317530, states[40]= 0.010960
Saving checkpoint... 
Iteration: 736965702, states[0] = -94.971719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750417915, states[0] = -94.961628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763654397, states[0] = -86.637395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776793755, states[0] = -94.899328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789886462, states[0] = -94.952020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802874269, states[0] = -94.947461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816136096, states[0] = -61.354298, states[40]= 0.000004
Saving checkpoint... 
Iteration: 829571901, states[0] = 0.381879, states[40]= 0.004487
Saving checkpoint... 
Iteration: 843026377, states[0] = 20.352535, states[40]= 0.007690
Saving checkpoint... 
Iteration: 855827789, states[0] = -94.924293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869206601, states[0] = -94.778626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881998360, states[0] = -94.976320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893227694, states[0] = -94.817743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906757445, states[0] = -94.861221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920218694, states[0] = -94.801902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933820161, states[0] = -94.919356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947322181, states[0] = -94.920681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960798774, states[0] = -94.903472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974332772, states[0] = -94.927237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987246403, states[0] = -94.846530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000745836, states[0] = -94.845726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014242575, states[0] = -94.841043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027314430, states[0] = -94.915379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038432554, states[0] = -94.965061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051817707, states[0] = -94.917639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065212725, states[0] = -94.790609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078803741, states[0] = -94.907403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092454752, states[0] = -94.969607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105641846, states[0] = -68.300726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1119021938, states[0] = 21.774504, states[40]= 0.009578
Saving checkpoint... 
Iteration: 1130916123, states[0] = -94.960956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144159631, states[0] = -92.016671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157163633, states[0] = -93.733694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170525759, states[0] = 20.558657, states[40]= 0.007876
Saving checkpoint... 
Iteration: 1183930477, states[0] = -94.964506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197520234, states[0] = 22.286035, states[40]= 0.010862
Saving checkpoint... 
Iteration: 1210337190, states[0] = -94.929660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223824360, states[0] = -94.921945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237159869, states[0] = -92.167152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250508832, states[0] = 26.408034, states[40]= 0.068771
Saving checkpoint... 
Iteration: 1263796247, states[0] = -94.901205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277273318, states[0] = -94.879394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290708938, states[0] = -94.783084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304253813, states[0] = -94.856374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317751505, states[0] = -94.853330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331236048, states[0] = -94.831048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344716663, states[0] = -94.797926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358238889, states[0] = -94.835390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371469596, states[0] = -94.972025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384963782, states[0] = -94.971057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397935219, states[0] = -94.965474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411414294, states[0] = -94.960317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424855542, states[0] = -94.939033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438359222, states[0] = -94.940734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451824176, states[0] = -94.921707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465262956, states[0] = -94.867645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478484535, states[0] = -94.974207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491863217, states[0] = -94.942495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505145683, states[0] = 10.306555, states[40]= 0.006045
Saving checkpoint... 
Iteration: 1517981042, states[0] = -95.237648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531021347, states[0] = -66.112066, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1544285161, states[0] = -95.125827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557707250, states[0] = -49.438064, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1570865892, states[0] = -3.878064, states[40]= 0.004191
Saving checkpoint... 
Iteration: 1583931514, states[0] = -95.225996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596778762, states[0] = -95.128672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610111151, states[0] = 25.624789, states[40]= 0.042695
Saving checkpoint... 
Iteration: 1623492910, states[0] = -95.163404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636892574, states[0] = -32.958883, states[40]= 0.000329
Saving checkpoint... 
Iteration: 1650273083, states[0] = -95.278209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663359630, states[0] = -95.076032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676778918, states[0] = -17.572163, states[40]= 0.001328
Saving checkpoint... 
Iteration: 1690134274, states[0] = -95.235874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702930924, states[0] = -83.555374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716341497, states[0] = 11.604204, states[40]= 0.006413
Saving checkpoint... 
Iteration: 1729777127, states[0] = -95.282377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743239942, states[0] = -95.243458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756303726, states[0] = -45.941037, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1767388005, states[0] = -27.862453, states[40]= 0.000559
Saving checkpoint... 
Iteration: 1780554632, states[0] = 4.023195, states[40]= 0.005519
Saving checkpoint... 
Iteration: 1793965264, states[0] = -95.271618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807316262, states[0] = -94.978572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820801711, states[0] = -94.950612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834097564, states[0] = -22.629459, states[40]= 0.000823
Saving checkpoint... 
Iteration: 1847469210, states[0] = -94.992986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860899239, states[0] = -94.970106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873897217, states[0] = -94.964935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887365330, states[0] = -94.949898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900626095, states[0] = -50.427631, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1914071518, states[0] = 0.528007, states[40]= 0.004510
Saving checkpoint... 
Iteration: 1927487224, states[0] = -94.976422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940358473, states[0] = -94.941556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953798055, states[0] = -94.903320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967175161, states[0] = -94.671660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980622406, states[0] = -46.146303, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1994040053, states[0] = 15.217765, states[40]= 0.005779
Saving checkpoint... 
Iteration: 2007464112, states[0] = -94.970959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020883353, states[0] = -94.950368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034362469, states[0] = -94.941937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047698674, states[0] = -94.761555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060029760, states[0] = 19.179033, states[40]= 0.006920
Saving checkpoint... 
Iteration: 2073489847, states[0] = -94.974606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086892046, states[0] = -94.953236, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.851729
 - CaMKt in component CaMK (millimolar): 0.006645
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.560019
 - nass in component intracellular_ions (millimolar): 6.560078
 - ki in component intracellular_ions (millimolar): 145.421122
 - kss in component intracellular_ions (millimolar): 145.421102
 - cansr in component intracellular_ions (millimolar): 1.301108
 - cajsr in component intracellular_ions (millimolar): 1.264096
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003637
 - hf in component INa (dimensionless): 0.879128
 - hs in component INa (dimensionless): 0.879124
 - j in component INa (dimensionless): 0.879093
 - hsp in component INa (dimensionless): 0.724187
 - jp in component INa (dimensionless): 0.879073
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709526
 - hLp in component INaL (dimensionless): 0.453257
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.625801
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.700935
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936335
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001580
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342191
 - xs1 in component IKs (dimensionless): 0.234240
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:44:11 (7004): called boinc_finish(0)

</stderr_txt>
]]>


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