𝕏

Task 54708921

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Ks_95-conf_617_0
Workunit 25976155
Created 25 Jun 2024, 9:33:39 UTC
Sent 25 Jun 2024, 20:31:22 UTC
Report deadline 28 Jun 2024, 23:24:10 UTC
Received 28 Jun 2024, 17:22:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 43 min 24 sec
CPU time 1 hours 56 min 30 sec
Validate state Valid
Credit 50.08
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.29 MB
Peak swap size 5.42 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Ks_95-conf_617.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Ks_95-conf_617_0_r590031787_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Ks_95-conf_617_0_r590031787_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 97.858326
     * GNaL_b in INaL: 0.007711
     * Gto_b in Ito: 0.086559
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033353
     * GKs_b in IKs: 0.000091
     * GK1_b in IK1: 0.169479
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 63.598886
     * GKb_b in IKb: 0.003931
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048534
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10449061, states[0] = -94.999240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22465892, states[0] = -94.977047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35102176, states[0] = -8.908027, states[40]= 0.002909
Saving checkpoint... 
Iteration: 47695405, states[0] = -94.560182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60384232, states[0] = -94.939015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72992544, states[0] = -94.980643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85303659, states[0] = -94.862508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97710787, states[0] = -94.630889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109380168, states[0] = -94.939196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121917541, states[0] = -94.959545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133964398, states[0] = -94.976132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143982651, states[0] = -94.980743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156448139, states[0] = -94.971450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168961652, states[0] = -94.975546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181485602, states[0] = -94.981487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194009718, states[0] = 27.843511, states[40]= 0.054392
Saving checkpoint... 
Iteration: 206479675, states[0] = -94.980112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218886286, states[0] = -94.943546, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Ks_95-conf_617.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Ks_95-conf_617_0_r590031787_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-CLVPET_Block_Ks_95-conf_617_0_r590031787_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 97.858326
     * GNaL_b in INaL: 0.007711
     * Gto_b in Ito: 0.086559
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033353
     * GKs_b in IKs: 0.000091
     * GK1_b in IK1: 0.169479
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 63.598886
     * GKb_b in IKb: 0.003931
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048534
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 218886286
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.943546 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 228263345, states[0] = -94.790482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236586047, states[0] = 2.508106, states[40]= 0.004597
Saving checkpoint... 
Iteration: 247223966, states[0] = -94.679573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252049800, states[0] = 18.724640, states[40]= 0.002291
Saving checkpoint... 
Iteration: 260588353, states[0] = 1.113871, states[40]= 0.004559
Saving checkpoint... 
Iteration: 274508854, states[0] = 27.879510, states[40]= 0.072776
Saving checkpoint... 
Iteration: 288478776, states[0] = -94.979599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302439841, states[0] = -94.968278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316241214, states[0] = -94.733579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325917813, states[0] = -94.959492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334799822, states[0] = -94.857786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344709449, states[0] = -94.626029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356751883, states[0] = -94.762370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370601680, states[0] = -8.821505, states[40]= 0.002928
Saving checkpoint... 
Iteration: 384637835, states[0] = -42.503684, states[40]= 0.000312
Saving checkpoint... 
Iteration: 398636530, states[0] = -41.185310, states[40]= 0.000370
Saving checkpoint... 
Iteration: 412598770, states[0] = -6.348061, states[40]= 0.003486
Saving checkpoint... 
Iteration: 426703803, states[0] = -94.603078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436769135, states[0] = -94.802244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446894800, states[0] = -94.947537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460849855, states[0] = -94.915657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474874458, states[0] = -94.934818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488832276, states[0] = -94.898439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502873578, states[0] = -94.934088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516726616, states[0] = -94.687354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530661210, states[0] = -69.587470, states[40]= 0.000005
Saving checkpoint... 
Iteration: 544333806, states[0] = -94.899810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558373864, states[0] = -94.934040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571865348, states[0] = -94.927835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585846259, states[0] = -94.911859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600054238, states[0] = 17.083053, states[40]= 0.002635
Saving checkpoint... 
Iteration: 614127691, states[0] = -32.693795, states[40]= 0.000947
Saving checkpoint... 
Iteration: 628440458, states[0] = -94.967057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642714882, states[0] = -94.645359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656867698, states[0] = -94.929209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671128210, states[0] = -33.176657, states[40]= 0.000908
Saving checkpoint... 
Iteration: 681694460, states[0] = -94.555982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695822146, states[0] = -94.886126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709646888, states[0] = -52.177733, states[40]= 0.000079
Saving checkpoint... 
Iteration: 723753941, states[0] = -94.765944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737908137, states[0] = -94.953194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752153715, states[0] = -59.983176, states[40]= 0.000023
Saving checkpoint... 
Iteration: 766269980, states[0] = -94.802557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780431036, states[0] = -94.962931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794715909, states[0] = -94.648479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807082768, states[0] = 4.372418, states[40]= 0.004568
Saving checkpoint... 
Iteration: 819393485, states[0] = -94.945152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833595495, states[0] = -3.766217, states[40]= 0.004003
Saving checkpoint... 
Iteration: 847744137, states[0] = -94.739480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862035461, states[0] = 23.664524, states[40]= 0.001429
Saving checkpoint... 
Iteration: 876080341, states[0] = 5.675842, states[40]= 0.004498
Saving checkpoint... 
Iteration: 889355982, states[0] = -94.919015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902839478, states[0] = -94.903992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915416365, states[0] = -94.956245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925336629, states[0] = -94.901036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938935654, states[0] = -94.963965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951729782, states[0] = -94.695821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965370062, states[0] = -94.929561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979373307, states[0] = -94.931790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989852065, states[0] = -94.915249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000167221, states[0] = -79.104727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010932920, states[0] = -94.962629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021980590, states[0] = -94.976786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030243447, states[0] = -94.736736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040396631, states[0] = -94.945922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048080949, states[0] = 5.355216, states[40]= 0.004519
Saving checkpoint... 
Iteration: 1059590104, states[0] = 0.003626, states[40]= 0.004491
Saving checkpoint... 
Iteration: 1069936747, states[0] = -94.963785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081738159, states[0] = -94.721234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091770741, states[0] = -94.802696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101855863, states[0] = -94.917975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114362493, states[0] = -94.923249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122410525, states[0] = -94.952640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130532006, states[0] = 24.729475, states[40]= 0.001298
Saving checkpoint... 
Iteration: 1140080560, states[0] = 5.561146, states[40]= 0.004506
Saving checkpoint... 
Iteration: 1150461227, states[0] = -94.971280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160179997, states[0] = -93.669018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170540381, states[0] = 22.043668, states[40]= 0.001675
Saving checkpoint... 
Iteration: 1179627559, states[0] = -32.569008, states[40]= 0.000957
Saving checkpoint... 
Iteration: 1187561388, states[0] = 14.306611, states[40]= 0.003226
Saving checkpoint... 
Iteration: 1196837540, states[0] = -94.900755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206673259, states[0] = -88.981310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216253035, states[0] = -94.761467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226233027, states[0] = -94.704930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234919747, states[0] = -94.956318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243858439, states[0] = -94.919460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253753331, states[0] = -94.762047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263188180, states[0] = -94.473454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269116937, states[0] = -22.854344, states[40]= 0.001361
Saving checkpoint... 
Iteration: 1273431748, states[0] = -94.961024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281516547, states[0] = 27.876919, states[40]= 0.006019
Saving checkpoint... 
Iteration: 1289002695, states[0] = 39.305929, states[40]= 0.498608
Saving checkpoint... 
Iteration: 1299149518, states[0] = -55.126111, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1311427805, states[0] = -94.959320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322316041, states[0] = -94.875860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331899536, states[0] = -94.946197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341881172, states[0] = -94.935432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352466229, states[0] = -94.971761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364379654, states[0] = -94.934353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374471634, states[0] = -94.973069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382964352, states[0] = -94.971119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391966730, states[0] = -94.971720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401859825, states[0] = -94.919875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411214690, states[0] = -94.641199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421079800, states[0] = 5.959488, states[40]= 0.004478
Saving checkpoint... 
Iteration: 1429692104, states[0] = -94.533479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439050770, states[0] = 18.371665, states[40]= 0.002365
Saving checkpoint... 
Iteration: 1446799823, states[0] = -94.852849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456488264, states[0] = -94.976560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466556722, states[0] = 16.140198, states[40]= 0.002838
Saving checkpoint... 
Iteration: 1476051019, states[0] = 18.280368, states[40]= 0.002384
Saving checkpoint... 
Iteration: 1485403357, states[0] = -94.947507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494916120, states[0] = -94.953573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506478678, states[0] = -78.740969, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1516958584, states[0] = -94.841195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527339429, states[0] = -0.724419, states[40]= 0.003984
Saving checkpoint... 
Iteration: 1536940980, states[0] = -94.891549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546646752, states[0] = -94.868163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556049733, states[0] = 19.669762, states[40]= 0.001752
Saving checkpoint... 
Iteration: 1565128419, states[0] = -24.891265, states[40]= 0.001477
Saving checkpoint... 
Iteration: 1574324708, states[0] = -94.625205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583840283, states[0] = -94.684623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593238471, states[0] = -94.665888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602933024, states[0] = -94.610583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612495975, states[0] = -94.654324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621664567, states[0] = -94.580813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631793575, states[0] = -94.571074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641760794, states[0] = -94.564865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651702608, states[0] = -94.560289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661082283, states[0] = -94.565827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671059958, states[0] = -94.562976, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.421187
 - CaMKt in component CaMK (millimolar): 0.001150
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.521040
 - nass in component intracellular_ions (millimolar): 6.521127
 - ki in component intracellular_ions (millimolar): 145.368457
 - kss in component intracellular_ions (millimolar): 145.368445
 - cansr in component intracellular_ions (millimolar): 1.579970
 - cajsr in component intracellular_ions (millimolar): 1.580018
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003798
 - hf in component INa (dimensionless): 0.871405
 - hs in component INa (dimensionless): 0.871406
 - j in component INa (dimensionless): 0.871407
 - hsp in component INa (dimensionless): 0.709862
 - jp in component INa (dimensionless): 0.871407
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.716313
 - hLp in component INaL (dimensionless): 0.524469
 - a in component Ito (dimensionless): 0.000644
 - iF in component Ito (dimensionless): 0.999858
 - iS in component Ito (dimensionless): 0.997757
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999858
 - iSp in component Ito (dimensionless): 0.999260
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998815
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003099
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001765
 - xs1 in component IKs (dimensionless): 0.023521
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997461
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:21:49 (7836): called boinc_finish(0)

</stderr_txt>
]]>


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