𝕏

Task 54706624

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1
Workunit 25975006
Created 25 Jun 2024, 9:32:40 UTC
Sent 25 Jun 2024, 20:09:05 UTC
Report deadline 28 Jun 2024, 20:09:05 UTC
Received 26 Jun 2024, 1:47:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 1 hours 54 min 39 sec
CPU time 1 hours 11 min 53 sec
Validate state Valid
Credit 41.68
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.73 MB
Peak swap size 391.75 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.565068
     * GNaL_b in INaL: 0.006887
     * Gto_b in Ito: 0.089500
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032732
     * GKs_b in IKs: 0.001752
     * GK1_b in IK1: 0.154560
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 62.613075
     * GKb_b in IKb: 0.003875
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038684
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 21501734, states[0] = -93.953024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48768033, states[0] = -93.979554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70110621, states[0] = -4.473511, states[40]= 0.003051
Saving checkpoint... 
Iteration: 94666713, states[0] = -93.997456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116751929, states[0] = -94.001518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138866187, states[0] = -93.999113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158287567, states[0] = -93.677120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183376912, states[0] = -93.878256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205246212, states[0] = -93.503505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227558445, states[0] = -93.992634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249618348, states[0] = -94.001436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272043685, states[0] = 25.860547, states[40]= 0.000151
Saving checkpoint... 
Iteration: 293986814, states[0] = -93.993918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316115224, states[0] = -8.616391, states[40]= 0.002466
Saving checkpoint... 
Iteration: 336904416, states[0] = -93.998385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361534392, states[0] = -93.986299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382412485, states[0] = -93.918840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407610262, states[0] = -93.999854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431230104, states[0] = -93.413520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454425652, states[0] = -93.930282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478121620, states[0] = -14.067602, states[40]= 0.001718
Saving checkpoint... 
Iteration: 501149134, states[0] = -36.428863, states[40]= 0.001176
Saving checkpoint... 
Iteration: 523714728, states[0] = -94.004036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549487724, states[0] = -93.968642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572533797, states[0] = -93.984980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594745040, states[0] = -94.003402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618100666, states[0] = 1.526396, states[40]= 0.002901
Saving checkpoint... 
Iteration: 639939573, states[0] = -93.994770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661932256, states[0] = -93.995063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684421234, states[0] = -93.925215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706111325, states[0] = -5.527102, states[40]= 0.002869
Saving checkpoint... 
Iteration: 729277509, states[0] = -93.638967, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.565068
     * GNaL_b in INaL: 0.006887
     * Gto_b in Ito: 0.089500
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032732
     * GKs_b in IKs: 0.001752
     * GK1_b in IK1: 0.154560
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 62.613075
     * GKb_b in IKb: 0.003875
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038684
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 729277509
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.638967 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 749477866, states[0] = -93.962871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770142452, states[0] = -31.089426, states[40]= 0.001801
Saving checkpoint... 
Iteration: 794250584, states[0] = -93.522105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818365686, states[0] = -93.859140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843141021, states[0] = -29.956419, states[40]= 0.001902
Saving checkpoint... 
Iteration: 865013577, states[0] = 31.152441, states[40]= 0.018010
Saving checkpoint... 
Iteration: 887499137, states[0] = -93.971632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910092329, states[0] = 5.989759, states[40]= 0.002285
Saving checkpoint... 
Iteration: 934460007, states[0] = -93.952103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958866902, states[0] = -93.996948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985308109, states[0] = -93.737617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010630335, states[0] = -93.998407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035529501, states[0] = -93.981219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059030565, states[0] = 29.639374, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1085971569, states[0] = -93.990481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111362102, states[0] = -93.851911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135355840, states[0] = -93.841478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164844272, states[0] = -93.996916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191190634, states[0] = -73.517363, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1216722643, states[0] = -94.000217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241826255, states[0] = -93.997304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267362473, states[0] = -93.851638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293095151, states[0] = 4.551143, states[40]= 0.002515
Saving checkpoint... 
Iteration: 1318572980, states[0] = -93.989635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338537222, states[0] = -93.981700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361092636, states[0] = 5.837429, states[40]= 0.002311
Saving checkpoint... 
Iteration: 1381900276, states[0] = -93.992877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402854285, states[0] = -93.995132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422246341, states[0] = -93.497670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436988640, states[0] = -93.987559, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.565068
     * GNaL_b in INaL: 0.006887
     * Gto_b in Ito: 0.089500
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032732
     * GKs_b in IKs: 0.001752
     * GK1_b in IK1: 0.154560
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 62.613075
     * GKb_b in IKb: 0.003875
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038684
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1436988640
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.987559 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1485770236, states[0] = -93.997964, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Drouin_ENDO_2000-conf_614_1_r2062586997_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.565068
     * GNaL_b in INaL: 0.006887
     * Gto_b in Ito: 0.089500
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032732
     * GKs_b in IKs: 0.001752
     * GK1_b in IK1: 0.154560
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 62.613075
     * GKb_b in IKb: 0.003875
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038684
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1485770236
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.997964 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.862488
 - CaMKt in component CaMK (millimolar): 0.006052
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.097789
 - nass in component intracellular_ions (millimolar): 7.097911
 - ki in component intracellular_ions (millimolar): 144.724615
 - kss in component intracellular_ions (millimolar): 144.724600
 - cansr in component intracellular_ions (millimolar): 1.899670
 - cajsr in component intracellular_ions (millimolar): 1.898875
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.004019
 - hf in component INa (dimensionless): 0.860764
 - hs in component INa (dimensionless): 0.860766
 - j in component INa (dimensionless): 0.860780
 - hsp in component INa (dimensionless): 0.690612
 - jp in component INa (dimensionless): 0.860788
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.700810
 - hLp in component INaL (dimensionless): 0.487687
 - a in component Ito (dimensionless): 0.000669
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.885677
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.925253
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.971439
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005023
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.111842
 - xs1 in component IKs (dimensionless): 0.135460
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997597
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:46:49 (10952): called boinc_finish(0)

</stderr_txt>
]]>