𝕏

Task 54703439

Name HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pieske_1000-conf_910_0
Workunit 25973414
Created 25 Jun 2024, 9:31:10 UTC
Sent 25 Jun 2024, 19:44:18 UTC
Report deadline 28 Jun 2024, 19:44:18 UTC
Received 26 Jun 2024, 4:47:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 38 min 18 sec
CPU time 1 hours 32 min 48 sec
Validate state Valid
Credit 42.12
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.97 MB
Peak swap size 4.13 GB
Peak disk usage 0.70 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pieske_1000-conf_910.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pieske_1000-conf_910_0_r1230774396_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pieske_1000-conf_910_0_r1230774396_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.719167
     * GNaL_b in INaL: 0.005583
     * Gto_b in Ito: 0.088453
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033045
     * GKs_b in IKs: 0.001859
     * GK1_b in IK1: 0.143340
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 63.244453
     * GKb_b in IKb: 0.003868
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038354
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13458253, states[0] = -87.117769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25400084, states[0] = -87.061140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38706280, states[0] = -86.831791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51656574, states[0] = -85.066180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65231891, states[0] = -86.852985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78418393, states[0] = -87.000882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91347988, states[0] = -86.965668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102350135, states[0] = -86.963545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108380501, states[0] = -86.977073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121828276, states[0] = -86.945737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135598559, states[0] = -21.789958, states[40]= 0.000803
Saving checkpoint... 
Iteration: 148966217, states[0] = -86.996513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161432753, states[0] = -86.988366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174624389, states[0] = -48.460286, states[40]= 0.000031
Saving checkpoint... 
Iteration: 187346682, states[0] = -86.952929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199691452, states[0] = -86.740488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210638628, states[0] = -64.341331, states[40]= 0.000002
Saving checkpoint... 
Iteration: 224038918, states[0] = 15.728298, states[40]= 0.004844
Saving checkpoint... 
Iteration: 236585257, states[0] = -8.468707, states[40]= 0.002615
Saving checkpoint... 
Iteration: 249241070, states[0] = -86.842203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261494293, states[0] = -86.998476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274779381, states[0] = -86.895712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288280131, states[0] = -86.896533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301837400, states[0] = -86.946228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315759852, states[0] = -86.870827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328910753, states[0] = -86.980061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341326606, states[0] = -86.938826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354501259, states[0] = 41.459418, states[40]= 0.067102
Saving checkpoint... 
Iteration: 366565821, states[0] = 4.316855, states[40]= 0.004526
Saving checkpoint... 
Iteration: 381120169, states[0] = -43.914705, states[40]= 0.000064
Saving checkpoint... 
Iteration: 394938110, states[0] = -86.987655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407808044, states[0] = -86.924150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420722129, states[0] = -86.807228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433853516, states[0] = -86.955706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446175207, states[0] = -86.675953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458400168, states[0] = -86.976400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471304881, states[0] = -86.921329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483559029, states[0] = 7.512462, states[40]= 0.004647
Saving checkpoint... 
Iteration: 495931013, states[0] = -86.985776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508429909, states[0] = -86.985476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521432690, states[0] = -86.986193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533940596, states[0] = -86.988148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546851450, states[0] = -86.954469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560042543, states[0] = 14.345807, states[40]= 0.004760
Saving checkpoint... 
Iteration: 572891828, states[0] = -86.973256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584987881, states[0] = -86.997173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597331794, states[0] = -86.942245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609449110, states[0] = -86.990045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622241696, states[0] = -86.842789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634932850, states[0] = -86.986148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647355924, states[0] = -86.956855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660146503, states[0] = -74.295292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672867172, states[0] = -86.962575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685419784, states[0] = -86.982525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697248241, states[0] = -86.853314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710118148, states[0] = -41.793148, states[40]= 0.000089
Saving checkpoint... 
Iteration: 722652119, states[0] = -80.922387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735597287, states[0] = -20.335646, states[40]= 0.000895
Saving checkpoint... 
Iteration: 748672077, states[0] = -86.636946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761340571, states[0] = -86.947852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774626700, states[0] = -50.890163, states[40]= 0.000021
Saving checkpoint... 
Iteration: 787733546, states[0] = -86.828540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800855756, states[0] = -86.956648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813996762, states[0] = -86.998278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826945765, states[0] = -86.989132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839912497, states[0] = -86.980205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853056242, states[0] = 8.739514, states[40]= 0.004669
Saving checkpoint... 
Iteration: 866027444, states[0] = 19.614736, states[40]= 0.005682
Saving checkpoint... 
Iteration: 878785422, states[0] = -86.901901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892439710, states[0] = -86.987663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905145185, states[0] = -72.578501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917892180, states[0] = -86.973128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930696007, states[0] = -86.750104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942995952, states[0] = -86.998069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955434185, states[0] = -86.986247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967970288, states[0] = -86.993990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981209437, states[0] = -86.780378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993688339, states[0] = -86.731454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005952865, states[0] = -86.990557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018760925, states[0] = -86.871754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032133001, states[0] = -57.808140, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1045270717, states[0] = -86.884633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058177457, states[0] = -86.692103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070456503, states[0] = -86.991268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082622698, states[0] = -46.593675, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1095333034, states[0] = -86.942707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107721106, states[0] = -86.804662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120647847, states[0] = -76.020460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133847685, states[0] = -86.951867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146699859, states[0] = -86.758852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159104398, states[0] = -27.637154, states[40]= 0.000520
Saving checkpoint... 
Iteration: 1172223093, states[0] = -86.808555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184821922, states[0] = -86.934733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198158891, states[0] = -85.221786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210592423, states[0] = -15.355631, states[40]= 0.001389
Saving checkpoint... 
Iteration: 1223229180, states[0] = -86.820199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235653061, states[0] = -81.798084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247685855, states[0] = -86.724641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260925751, states[0] = -86.983782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272947302, states[0] = -86.989141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284637072, states[0] = -62.466820, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1296673684, states[0] = -86.659441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307082139, states[0] = -5.822594, states[40]= 0.003166
Saving checkpoint... 
Iteration: 1318980647, states[0] = -86.995489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331550116, states[0] = 11.319114, states[40]= 0.004693
Saving checkpoint... 
Iteration: 1344299768, states[0] = -86.915997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357615980, states[0] = -39.536408, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1370196637, states[0] = -86.751237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383298550, states[0] = -86.914819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395677913, states[0] = -86.694524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408334634, states[0] = -86.943538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420983547, states[0] = -86.995874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432772926, states[0] = -86.887077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445580061, states[0] = -4.215780, states[40]= 0.003482
Saving checkpoint... 
Iteration: 1457926528, states[0] = -86.983846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470652399, states[0] = -81.190654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484229813, states[0] = -86.821179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497985295, states[0] = -86.996088, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.874073
 - CaMKt in component CaMK (millimolar): 0.006850
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.526390
 - nass in component intracellular_ions (millimolar): 6.526449
 - ki in component intracellular_ions (millimolar): 145.455236
 - kss in component intracellular_ions (millimolar): 145.455215
 - cansr in component intracellular_ions (millimolar): 1.302163
 - cajsr in component intracellular_ions (millimolar): 1.264497
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008124
 - hf in component INa (dimensionless): 0.662260
 - hs in component INa (dimensionless): 0.662247
 - j in component INa (dimensionless): 0.662176
 - hsp in component INa (dimensionless): 0.414466
 - jp in component INa (dimensionless): 0.662127
 - mL in component INaL (dimensionless): 0.000228
 - hL in component INaL (dimensionless): 0.467210
 - hLp in component INaL (dimensionless): 0.241721
 - a in component Ito (dimensionless): 0.001071
 - iF in component Ito (dimensionless): 0.999469
 - iS in component Ito (dimensionless): 0.580758
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999469
 - iSp in component Ito (dimensionless): 0.636032
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937548
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001560
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.398144
 - xs1 in component IKs (dimensionless): 0.237832
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997013
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:44:02 (46473): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pieske_1000-conf_910.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pieske_1000-conf_910_0_r1230774396_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625112745323441_ORdGradInc_k_24-Pieske_1000-conf_910_0_r1230774396_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.719167
     * GNaL_b in INaL: 0.005583
     * Gto_b in Ito: 0.088453
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033045
     * GKs_b in IKs: 0.001859
     * GK1_b in IK1: 0.143340
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 63.244453
     * GKb_b in IKb: 0.003868
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038354
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1497985295
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.996088 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.874073
 - CaMKt in component CaMK (millimolar): 0.006850
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.526390
 - nass in component intracellular_ions (millimolar): 6.526449
 - ki in component intracellular_ions (millimolar): 145.455236
 - kss in component intracellular_ions (millimolar): 145.455215
 - cansr in component intracellular_ions (millimolar): 1.302163
 - cajsr in component intracellular_ions (millimolar): 1.264497
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008124
 - hf in component INa (dimensionless): 0.662260
 - hs in component INa (dimensionless): 0.662247
 - j in component INa (dimensionless): 0.662176
 - hsp in component INa (dimensionless): 0.414466
 - jp in component INa (dimensionless): 0.662127
 - mL in component INaL (dimensionless): 0.000228
 - hL in component INaL (dimensionless): 0.467210
 - hLp in component INaL (dimensionless): 0.241721
 - a in component Ito (dimensionless): 0.001071
 - iF in component Ito (dimensionless): 0.999469
 - iS in component Ito (dimensionless): 0.580758
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999469
 - iSp in component Ito (dimensionless): 0.636032
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937548
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001560
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.398144
 - xs1 in component IKs (dimensionless): 0.237832
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997013
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:47:17 (47469): called boinc_finish(0)

</stderr_txt>
]]>


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