𝕏

Task 54694079

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_297_1
Workunit 25968739
Created 25 Jun 2024, 9:26:57 UTC
Sent 25 Jun 2024, 18:40:49 UTC
Report deadline 29 Jun 2024, 4:16:49 UTC
Received 26 Jun 2024, 13:32:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241093
Run time 3 hours 8 min 59 sec
CPU time 3 hours 5 min 29 sec
Validate state Valid
Credit 62.12
Device peak FLOPS 3.91 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.05 MB
Peak swap size 5.27 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_297.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_297_1_r1396446790_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_297_1_r1396446790_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.644485
     * GNaL_b in INaL: 0.008969
     * Gto_b in Ito: 0.083801
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033049
     * GKs_b in IKs: 0.001843
     * GK1_b in IK1: 0.176161
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.027556
     * GKb_b in IKb: 0.003788
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032670
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12505253, states[0] = 28.646073, states[40]= 0.140523
Saving checkpoint... 
Iteration: 25075162, states[0] = 1.789394, states[40]= 0.004500
Saving checkpoint... 
Iteration: 37867622, states[0] = -95.155646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50402757, states[0] = -95.158153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62491295, states[0] = -95.169047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75333295, states[0] = -95.121706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88273080, states[0] = -95.075411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101232603, states[0] = -95.025168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114112536, states[0] = -25.731733, states[40]= 0.000727
Saving checkpoint... 
Iteration: 126995816, states[0] = -95.158930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139871782, states[0] = -95.131480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152829410, states[0] = -95.111966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165789765, states[0] = -95.085006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178601106, states[0] = -15.201654, states[40]= 0.001442
Saving checkpoint... 
Iteration: 190969700, states[0] = -95.153969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203559341, states[0] = 9.954079, states[40]= 0.004945
Saving checkpoint... 
Iteration: 216221061, states[0] = -95.003559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229058811, states[0] = 10.166753, states[40]= 0.004950
Saving checkpoint... 
Iteration: 241930109, states[0] = -95.146699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254776638, states[0] = -95.072971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267547787, states[0] = 14.338919, states[40]= 0.005074
Saving checkpoint... 
Iteration: 280390479, states[0] = -95.136465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293007562, states[0] = 25.594999, states[40]= 0.095178
Saving checkpoint... 
Iteration: 305687816, states[0] = -94.940999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318568988, states[0] = 5.897453, states[40]= 0.004790
Saving checkpoint... 
Iteration: 330849327, states[0] = -95.120984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343462917, states[0] = -95.152584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355567768, states[0] = 6.439394, states[40]= 0.004818
Saving checkpoint... 
Iteration: 367729276, states[0] = -95.016156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380249269, states[0] = -95.043420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392537048, states[0] = 18.044242, states[40]= 0.005477
Saving checkpoint... 
Iteration: 404787482, states[0] = -95.082407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417379653, states[0] = -95.132865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430006805, states[0] = 26.375401, states[40]= 0.111428
Saving checkpoint... 
Iteration: 442733759, states[0] = -95.022697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458867637, states[0] = -95.128516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471490368, states[0] = -95.156288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484024036, states[0] = 21.657706, states[40]= 0.007609
Saving checkpoint... 
Iteration: 496604769, states[0] = -18.493403, states[40]= 0.001102
Saving checkpoint... 
Iteration: 509127088, states[0] = -39.271447, states[40]= 0.000160
Saving checkpoint... 
Iteration: 521455374, states[0] = -95.151249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534212216, states[0] = -94.988359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546582046, states[0] = -0.710195, states[40]= 0.004159
Saving checkpoint... 
Iteration: 558773386, states[0] = -95.069661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571290555, states[0] = -95.084830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583176238, states[0] = -94.829228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595248346, states[0] = -95.042144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607669187, states[0] = -93.912837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620186996, states[0] = -94.938635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632745962, states[0] = -95.039119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645483701, states[0] = -95.155350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658181533, states[0] = -94.915478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670923255, states[0] = -95.144875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683516019, states[0] = 23.107220, states[40]= 0.016271
Saving checkpoint... 
Iteration: 696266271, states[0] = -95.062466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708516299, states[0] = 23.065812, states[40]= 0.015588
Saving checkpoint... 
Iteration: 720927652, states[0] = -95.145819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733527591, states[0] = 20.808388, states[40]= 0.006610
Saving checkpoint... 
Iteration: 746079758, states[0] = 0.585428, states[40]= 0.004333
Saving checkpoint... 
Iteration: 758796407, states[0] = -95.089312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771520664, states[0] = 22.344699, states[40]= 0.009457
Saving checkpoint... 
Iteration: 784267627, states[0] = -95.063808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797019193, states[0] = 22.607109, states[40]= 0.010827
Saving checkpoint... 
Iteration: 809736044, states[0] = -95.025722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822560136, states[0] = 9.640674, states[40]= 0.004936
Saving checkpoint... 
Iteration: 835453146, states[0] = -95.150679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848217369, states[0] = -94.996966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860866815, states[0] = -95.127955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873513696, states[0] = 23.450665, states[40]= 0.024475
Saving checkpoint... 
Iteration: 885884499, states[0] = -95.134187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898523086, states[0] = 21.863389, states[40]= 0.008004
Saving checkpoint... 
Iteration: 910036334, states[0] = 18.273356, states[40]= 0.005526
Saving checkpoint... 
Iteration: 922037330, states[0] = 17.953149, states[40]= 0.005459
Saving checkpoint... 
Iteration: 934469122, states[0] = -95.153162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946774762, states[0] = -95.070740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958916050, states[0] = -95.143014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970912448, states[0] = -95.142120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982980717, states[0] = -95.154754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995136559, states[0] = -49.471121, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1007100112, states[0] = -14.285522, states[40]= 0.001567
Saving checkpoint... 
Iteration: 1019248038, states[0] = -95.041499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031332213, states[0] = -95.112115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043171026, states[0] = -94.371688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055196390, states[0] = -94.958825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067562600, states[0] = 8.638850, states[40]= 0.004906
Saving checkpoint... 
Iteration: 1079573957, states[0] = 3.580457, states[40]= 0.004636
Saving checkpoint... 
Iteration: 1091675625, states[0] = -94.806441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103634840, states[0] = -47.514000, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1115396121, states[0] = -95.137622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126818835, states[0] = -95.104410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138102143, states[0] = -16.111731, states[40]= 0.001330
Saving checkpoint... 
Iteration: 1150025410, states[0] = 21.344135, states[40]= 0.007149
Saving checkpoint... 
Iteration: 1162109987, states[0] = -23.234573, states[40]= 0.000838
Saving checkpoint... 
Iteration: 1173968867, states[0] = -95.152978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185724608, states[0] = -95.008486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197352241, states[0] = -95.121752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209276365, states[0] = -95.072089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221261513, states[0] = -95.057091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232745163, states[0] = -95.037727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244140617, states[0] = -54.242988, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1255857877, states[0] = -95.124135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267309882, states[0] = -95.098614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279113701, states[0] = -26.617167, states[40]= 0.000686
Saving checkpoint... 
Iteration: 1291182215, states[0] = -94.919483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303065809, states[0] = 7.290519, states[40]= 0.004857
Saving checkpoint... 
Iteration: 1314826001, states[0] = -95.108515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326625458, states[0] = -37.654514, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1338740051, states[0] = -95.030923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350724107, states[0] = -95.007597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362640251, states[0] = -53.804304, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1374528686, states[0] = 20.523100, states[40]= 0.006400
Saving checkpoint... 
Iteration: 1386310827, states[0] = -95.099168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397745778, states[0] = -95.038413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409483080, states[0] = -95.154803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421281205, states[0] = -95.076373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433171115, states[0] = -94.387441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445189329, states[0] = -94.943939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457165704, states[0] = -91.921343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468904832, states[0] = -95.139842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480531117, states[0] = 19.853520, states[40]= 0.006032
Saving checkpoint... 
Iteration: 1492228479, states[0] = -95.014261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503773181, states[0] = -95.203994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515456375, states[0] = -95.120003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527126711, states[0] = -63.317668, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1538776339, states[0] = -7.360967, states[40]= 0.003266
Saving checkpoint... 
Iteration: 1550623678, states[0] = -95.329610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562428701, states[0] = 18.979241, states[40]= 0.007497
Saving checkpoint... 
Iteration: 1574113546, states[0] = 23.745540, states[40]= 0.026929
Saving checkpoint... 
Iteration: 1585671406, states[0] = -95.242619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597541150, states[0] = 13.519864, states[40]= 0.006130
Saving checkpoint... 
Iteration: 1609263553, states[0] = 1.579569, states[40]= 0.005053
Saving checkpoint... 
Iteration: 1621079013, states[0] = -95.263082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632737649, states[0] = -86.354732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644138788, states[0] = -88.396687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656010208, states[0] = 24.839651, states[40]= 0.052381
Saving checkpoint... 
Iteration: 1667994926, states[0] = -95.410222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679897972, states[0] = -95.302284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691640177, states[0] = -95.363558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703468966, states[0] = -2.154356, states[40]= 0.004459
Saving checkpoint... 
Iteration: 1715088805, states[0] = -95.406434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726855225, states[0] = 6.383920, states[40]= 0.005525
Saving checkpoint... 
Iteration: 1738417874, states[0] = -95.334854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750017815, states[0] = -53.627543, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1761799145, states[0] = -95.304513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773358576, states[0] = 4.513633, states[40]= 0.005371
Saving checkpoint... 
Iteration: 1784896355, states[0] = -95.299425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796633148, states[0] = -95.355293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808428541, states[0] = -95.192345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820024876, states[0] = 21.032356, states[40]= 0.007184
Saving checkpoint... 
Iteration: 1831646244, states[0] = -64.005667, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1843292876, states[0] = -95.103665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855061906, states[0] = 8.627843, states[40]= 0.004921
Saving checkpoint... 
Iteration: 1866760555, states[0] = -95.064460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878334028, states[0] = -95.118710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890042633, states[0] = 16.094050, states[40]= 0.005207
Saving checkpoint... 
Iteration: 1901821274, states[0] = -95.108430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913655210, states[0] = -74.830255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1925269659, states[0] = -95.066651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936831737, states[0] = -95.112336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951626194, states[0] = -38.433267, states[40]= 0.000180
Saving checkpoint... 
Iteration: 1963445815, states[0] = -95.149126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975385434, states[0] = -95.134113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986777670, states[0] = -95.073017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998430180, states[0] = -95.145700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010084045, states[0] = -1.912762, states[40]= 0.003972
Saving checkpoint... 
Iteration: 2021969103, states[0] = -95.152527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033946217, states[0] = -95.148727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045875544, states[0] = -95.130433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057785659, states[0] = -95.079833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069334431, states[0] = -95.112621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081024021, states[0] = 21.661117, states[40]= 0.007615
Saving checkpoint... 
Iteration: 2092697365, states[0] = -94.960037, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.032235
 - CaMKt in component CaMK (millimolar): 0.007147
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.622999
 - nass in component intracellular_ions (millimolar): 6.623062
 - ki in component intracellular_ions (millimolar): 145.352927
 - kss in component intracellular_ions (millimolar): 145.352906
 - cansr in component intracellular_ions (millimolar): 1.321069
 - cajsr in component intracellular_ions (millimolar): 1.282270
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003571
 - hf in component INa (dimensionless): 0.882245
 - hs in component INa (dimensionless): 0.882240
 - j in component INa (dimensionless): 0.882213
 - hsp in component INa (dimensionless): 0.730074
 - jp in component INa (dimensionless): 0.882195
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.712425
 - hLp in component INaL (dimensionless): 0.453218
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.616458
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.690215
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927925
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999861
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001650
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.346385
 - xs1 in component IKs (dimensionless): 0.255378
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997303
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:26:21 (1728): called boinc_finish(0)

</stderr_txt>
]]>


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