𝕏

Task 54694077

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_197_1
Workunit 25968738
Created 25 Jun 2024, 9:26:57 UTC
Sent 25 Jun 2024, 18:40:49 UTC
Report deadline 29 Jun 2024, 4:16:49 UTC
Received 26 Jun 2024, 11:17:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241093
Run time 3 hours 2 min 24 sec
CPU time 2 hours 59 min 12 sec
Validate state Valid
Credit 62.97
Device peak FLOPS 3.91 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.05 MB
Peak swap size 5.25 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_197.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_197_1_r467751168_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_197_1_r467751168_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.605719
     * GNaL_b in INaL: 0.006541
     * Gto_b in Ito: 0.082189
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033560
     * GKs_b in IKs: 0.001841
     * GK1_b in IK1: 0.177124
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 64.776851
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047617
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12669280, states[0] = -94.989348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25509149, states[0] = 23.627077, states[40]= 0.064434
Saving checkpoint... 
Iteration: 38120519, states[0] = -42.887671, states[40]= 0.000083
Saving checkpoint... 
Iteration: 50538177, states[0] = 15.794122, states[40]= 0.005426
Saving checkpoint... 
Iteration: 63468205, states[0] = -95.187001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76097393, states[0] = -18.698379, states[40]= 0.001061
Saving checkpoint... 
Iteration: 88806439, states[0] = -95.131191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101689416, states[0] = -94.990872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114557112, states[0] = 8.555463, states[40]= 0.004912
Saving checkpoint... 
Iteration: 127457798, states[0] = -95.177863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140089528, states[0] = -10.862617, states[40]= 0.002171
Saving checkpoint... 
Iteration: 152720943, states[0] = -95.042533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165132908, states[0] = -55.498989, states[40]= 0.000011
Saving checkpoint... 
Iteration: 177882982, states[0] = -95.160669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190164158, states[0] = -94.661464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202914047, states[0] = -95.168511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215064994, states[0] = 5.099906, states[40]= 0.004747
Saving checkpoint... 
Iteration: 227327897, states[0] = -95.138828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239976392, states[0] = -95.178947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252701109, states[0] = -95.009419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265431040, states[0] = -95.171840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277966789, states[0] = -95.177627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290525705, states[0] = 20.014374, states[40]= 0.007088
Saving checkpoint... 
Iteration: 302814901, states[0] = -95.131721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315346674, states[0] = -95.147348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328109559, states[0] = -30.170855, states[40]= 0.000445
Saving checkpoint... 
Iteration: 340538356, states[0] = 15.956610, states[40]= 0.005416
Saving checkpoint... 
Iteration: 353160282, states[0] = -93.893874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365808925, states[0] = -95.128150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377926264, states[0] = -95.170815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390141495, states[0] = -66.586798, states[40]= 0.000002
Saving checkpoint... 
Iteration: 402344588, states[0] = -95.146404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414720822, states[0] = -95.041470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426920998, states[0] = -95.169709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439271626, states[0] = -95.100600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451819762, states[0] = -95.134341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464490114, states[0] = -95.180366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477000571, states[0] = 23.982115, states[40]= 0.000986
Saving checkpoint... 
Iteration: 489661890, states[0] = -94.328568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502324967, states[0] = -95.137080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515003495, states[0] = 34.734168, states[40]= 0.141728
Saving checkpoint... 
Iteration: 527669819, states[0] = -94.909482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540285780, states[0] = -95.112217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553042434, states[0] = 14.452830, states[40]= 0.005221
Saving checkpoint... 
Iteration: 565792273, states[0] = -95.117020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581626589, states[0] = -48.021606, states[40]= 0.000038
Saving checkpoint... 
Iteration: 593905940, states[0] = -95.166230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606241352, states[0] = -95.069005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618515293, states[0] = 22.304781, states[40]= 0.018021
Saving checkpoint... 
Iteration: 631388977, states[0] = -95.161789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643930519, states[0] = -95.171486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656635426, states[0] = -58.540462, states[40]= 0.000007
Saving checkpoint... 
Iteration: 668877686, states[0] = -95.158412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681394537, states[0] = -95.163285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693751649, states[0] = -95.080787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706289383, states[0] = -95.114830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718913887, states[0] = -95.167998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731374032, states[0] = -95.157212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744094469, states[0] = -15.427248, states[40]= 0.001411
Saving checkpoint... 
Iteration: 757116056, states[0] = -36.675659, states[40]= 0.000202
Saving checkpoint... 
Iteration: 769922741, states[0] = -95.169866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782053587, states[0] = 10.073105, states[40]= 0.004965
Saving checkpoint... 
Iteration: 794534408, states[0] = 17.338673, states[40]= 0.005705
Saving checkpoint... 
Iteration: 807205618, states[0] = -95.016905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819652882, states[0] = -86.462501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832041668, states[0] = 14.740375, states[40]= 0.005251
Saving checkpoint... 
Iteration: 844211559, states[0] = -95.026793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856449843, states[0] = -95.174750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868768536, states[0] = -95.097561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881317011, states[0] = -95.132562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893903269, states[0] = -95.165400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906549769, states[0] = 11.612841, states[40]= 0.005027
Saving checkpoint... 
Iteration: 918729441, states[0] = -95.053474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930971424, states[0] = -95.177839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943281262, states[0] = -95.108430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955948160, states[0] = -95.174419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968568296, states[0] = 3.508797, states[40]= 0.004635
Saving checkpoint... 
Iteration: 980804154, states[0] = -95.124812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993106114, states[0] = -26.779379, states[40]= 0.000604
Saving checkpoint... 
Iteration: 1005650442, states[0] = -81.865332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018293262, states[0] = -95.117456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031041477, states[0] = 14.811763, states[40]= 0.005259
Saving checkpoint... 
Iteration: 1043987651, states[0] = -95.179746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056808732, states[0] = -95.127619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069599296, states[0] = -20.115308, states[40]= 0.000951
Saving checkpoint... 
Iteration: 1082434702, states[0] = -95.172011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095288467, states[0] = -95.113918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108174451, states[0] = -94.949813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121090947, states[0] = -12.095747, states[40]= 0.001937
Saving checkpoint... 
Iteration: 1133359382, states[0] = -95.151881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145360282, states[0] = -95.152208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157649517, states[0] = -80.069045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170156412, states[0] = -91.435285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182706297, states[0] = -95.017838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195368825, states[0] = -95.155206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207934955, states[0] = -95.171983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220088375, states[0] = -9.771699, states[40]= 0.002391
Saving checkpoint... 
Iteration: 1232554528, states[0] = 9.686186, states[40]= 0.004951
Saving checkpoint... 
Iteration: 1244984936, states[0] = -95.179317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257673939, states[0] = -94.947166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270443269, states[0] = -95.173417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283233347, states[0] = -95.058493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296203317, states[0] = -95.012636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308686638, states[0] = -94.981617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322527964, states[0] = 19.379342, states[40]= 0.006562
Saving checkpoint... 
Iteration: 1335097591, states[0] = -18.452744, states[40]= 0.001081
Saving checkpoint... 
Iteration: 1347885978, states[0] = -95.160505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362924810, states[0] = -95.169935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375492293, states[0] = -95.180061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388193224, states[0] = -94.994273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400859355, states[0] = -95.151712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413523190, states[0] = 20.664822, states[40]= 0.007967
Saving checkpoint... 
Iteration: 1426221189, states[0] = -95.041409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438784826, states[0] = -95.110945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451074119, states[0] = 0.419505, states[40]= 0.004320
Saving checkpoint... 
Iteration: 1463708026, states[0] = -95.020590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476038734, states[0] = 15.820428, states[40]= 0.005394
Saving checkpoint... 
Iteration: 1488180743, states[0] = -94.969136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500583928, states[0] = -95.359114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513217624, states[0] = 22.083182, states[40]= 0.014697
Saving checkpoint... 
Iteration: 1525612323, states[0] = -53.136980, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1537819095, states[0] = 21.405934, states[40]= 0.012360
Saving checkpoint... 
Iteration: 1550253221, states[0] = -95.217852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563103637, states[0] = -43.749577, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1575707674, states[0] = -49.045634, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1588402608, states[0] = -95.336648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601106233, states[0] = 27.533010, states[40]= 0.110121
Saving checkpoint... 
Iteration: 1613305245, states[0] = -95.343073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625599398, states[0] = -95.334393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637731189, states[0] = 16.577431, states[40]= 0.007014
Saving checkpoint... 
Iteration: 1649776948, states[0] = -13.954880, states[40]= 0.001837
Saving checkpoint... 
Iteration: 1662269832, states[0] = -95.415256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674787984, states[0] = -95.315409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687097809, states[0] = -95.332836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699329999, states[0] = -85.383587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711753005, states[0] = -95.401678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724314230, states[0] = -95.358001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736848087, states[0] = -95.196945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749308366, states[0] = 25.140366, states[40]= 0.074787
Saving checkpoint... 
Iteration: 1761553349, states[0] = -95.402015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774013812, states[0] = -57.696833, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1786616595, states[0] = -61.596662, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1799131217, states[0] = 16.552359, states[40]= 0.007009
Saving checkpoint... 
Iteration: 1811694907, states[0] = -95.035744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824289785, states[0] = -95.144744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836383971, states[0] = -95.181208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848793892, states[0] = -95.132619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861370233, states[0] = -95.165785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873925945, states[0] = -95.177146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886566564, states[0] = 4.208150, states[40]= 0.004693
Saving checkpoint... 
Iteration: 1899195445, states[0] = -95.001706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911663114, states[0] = -94.567163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923849325, states[0] = -95.149194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936758540, states[0] = -95.088475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949694625, states[0] = -94.997369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965115372, states[0] = -36.021640, states[40]= 0.000221
Saving checkpoint... 
Iteration: 1977806585, states[0] = -95.126075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990573201, states[0] = 0.926319, states[40]= 0.004382
Saving checkpoint... 
Iteration: 2003198277, states[0] = -95.003376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016025457, states[0] = 20.080045, states[40]= 0.007158
Saving checkpoint... 
Iteration: 2028481720, states[0] = -95.178509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041230392, states[0] = -95.054105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053926287, states[0] = -95.169809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066659291, states[0] = -93.493269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079523632, states[0] = 20.555021, states[40]= 0.007781
Saving checkpoint... 
Iteration: 2092328104, states[0] = -95.137694, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.056264
 - CaMKt in component CaMK (millimolar): 0.006831
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.715791
 - nass in component intracellular_ions (millimolar): 6.715851
 - ki in component intracellular_ions (millimolar): 145.263839
 - kss in component intracellular_ions (millimolar): 145.263819
 - cansr in component intracellular_ions (millimolar): 1.304085
 - cajsr in component intracellular_ions (millimolar): 1.266472
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003563
 - hf in component INa (dimensionless): 0.882654
 - hs in component INa (dimensionless): 0.882650
 - j in component INa (dimensionless): 0.882626
 - hsp in component INa (dimensionless): 0.730854
 - jp in component INa (dimensionless): 0.882610
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.715126
 - hLp in component INaL (dimensionless): 0.460152
 - a in component Ito (dimensionless): 0.000617
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.625805
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.701623
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935905
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001573
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327459
 - xs1 in component IKs (dimensionless): 0.239115
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997296
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:08:39 (7408): called boinc_finish(0)

</stderr_txt>
]]>


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