𝕏

Task 54690103

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_692_1
Workunit 25966753
Created 25 Jun 2024, 9:24:56 UTC
Sent 25 Jun 2024, 18:04:14 UTC
Report deadline 29 Jun 2024, 3:40:14 UTC
Received 25 Jun 2024, 20:40:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241028
Run time 2 hours 36 min 15 sec
CPU time 2 hours 34 min 11 sec
Validate state Valid
Credit 60.49
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.06 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_692.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_692_1_r1701459146_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_692_1_r1701459146_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.054188
     * GNaL_b in INaL: 0.007198
     * Gto_b in Ito: 0.067666
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033382
     * GKs_b in IKs: 0.001779
     * GK1_b in IK1: 0.148266
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 62.766366
     * GKb_b in IKb: 0.004041
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043823
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14057682, states[0] = 7.605751, states[40]= 0.005062
Saving checkpoint... 
Iteration: 28116302, states[0] = -38.665569, states[40]= 0.000156
Saving checkpoint... 
Iteration: 42239901, states[0] = -94.774458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56351590, states[0] = -94.865368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70286852, states[0] = -94.819736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84407960, states[0] = -94.880433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98556439, states[0] = 8.684618, states[40]= 0.005139
Saving checkpoint... 
Iteration: 112496361, states[0] = -94.894347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126534225, states[0] = 17.824618, states[40]= 0.006133
Saving checkpoint... 
Iteration: 140736467, states[0] = -94.755296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155272124, states[0] = -94.799630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169476509, states[0] = -94.890222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184021011, states[0] = 22.218399, states[40]= 0.009829
Saving checkpoint... 
Iteration: 198152032, states[0] = -80.474450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212488610, states[0] = -94.891540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226628430, states[0] = -50.314513, states[40]= 0.000027
Saving checkpoint... 
Iteration: 240861706, states[0] = -94.860249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255328715, states[0] = -94.843694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269317360, states[0] = -94.836628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283525842, states[0] = 20.758787, states[40]= 0.007594
Saving checkpoint... 
Iteration: 297868763, states[0] = -94.863075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312001411, states[0] = 49.259191, states[40]= 0.053315
Saving checkpoint... 
Iteration: 326228580, states[0] = -94.742104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340405325, states[0] = -94.875288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354439715, states[0] = -94.883486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368413140, states[0] = -94.877379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382597825, states[0] = -19.545933, states[40]= 0.001021
Saving checkpoint... 
Iteration: 396950042, states[0] = -94.885444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410989458, states[0] = -94.891421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425045878, states[0] = 13.232126, states[40]= 0.005408
Saving checkpoint... 
Iteration: 438936833, states[0] = -94.882848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452941885, states[0] = -94.883863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466948660, states[0] = -94.885150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481028818, states[0] = 19.773852, states[40]= 0.006895
Saving checkpoint... 
Iteration: 495009732, states[0] = 25.678402, states[40]= 0.055458
Saving checkpoint... 
Iteration: 508931628, states[0] = -94.881703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522842208, states[0] = -94.850920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536799865, states[0] = -94.823905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550824297, states[0] = -94.840847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564718124, states[0] = -94.724341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578424572, states[0] = -94.880074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592370198, states[0] = -94.863466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605988374, states[0] = -94.891176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620265258, states[0] = -94.791404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634458777, states[0] = -94.886841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648172805, states[0] = -94.528095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661918740, states[0] = -94.878630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675582709, states[0] = -5.891571, states[40]= 0.003307
Saving checkpoint... 
Iteration: 689401495, states[0] = -94.873999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703237348, states[0] = -94.755404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717285659, states[0] = -94.811851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731219036, states[0] = -94.725850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745024911, states[0] = 21.054163, states[40]= 0.007886
Saving checkpoint... 
Iteration: 758863032, states[0] = -94.860468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772815050, states[0] = -94.834789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786699607, states[0] = -94.689156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800573181, states[0] = 0.446102, states[40]= 0.004459
Saving checkpoint... 
Iteration: 814460707, states[0] = -94.887062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828690775, states[0] = -94.670605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842940324, states[0] = -94.883334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857127483, states[0] = -49.257695, states[40]= 0.000032
Saving checkpoint... 
Iteration: 870841692, states[0] = -94.850460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884496407, states[0] = -94.891992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898332300, states[0] = -94.845366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912248934, states[0] = -94.771453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926284989, states[0] = -94.811126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940265345, states[0] = -94.791321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954141080, states[0] = -64.934906, states[40]= 0.000002
Saving checkpoint... 
Iteration: 968046054, states[0] = 13.159578, states[40]= 0.005402
Saving checkpoint... 
Iteration: 982094415, states[0] = -16.264099, states[40]= 0.001341
Saving checkpoint... 
Iteration: 996220940, states[0] = -94.729007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010181753, states[0] = -94.644299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024231697, states[0] = -94.746643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038292928, states[0] = -94.818003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052538303, states[0] = 16.282002, states[40]= 0.005785
Saving checkpoint... 
Iteration: 1066826306, states[0] = -94.841776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080919348, states[0] = -94.878545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095050671, states[0] = 11.228393, states[40]= 0.005270
Saving checkpoint... 
Iteration: 1109273160, states[0] = -94.799583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123464780, states[0] = -94.887548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137726334, states[0] = -94.737996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152019459, states[0] = 22.655086, states[40]= 0.011171
Saving checkpoint... 
Iteration: 1166104017, states[0] = -25.509177, states[40]= 0.000688
Saving checkpoint... 
Iteration: 1180223502, states[0] = -94.733265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194121803, states[0] = -43.112182, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1208089127, states[0] = -11.303954, states[40]= 0.002138
Saving checkpoint... 
Iteration: 1221705347, states[0] = -94.700266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235347163, states[0] = -94.853006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249042536, states[0] = 14.598191, states[40]= 0.005542
Saving checkpoint... 
Iteration: 1262693766, states[0] = -94.676851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276407756, states[0] = -94.875435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290183749, states[0] = -94.651835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304018668, states[0] = 22.870957, states[40]= 0.012065
Saving checkpoint... 
Iteration: 1317964309, states[0] = -94.887364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331798167, states[0] = -94.822120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345765853, states[0] = -94.791657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359674918, states[0] = -94.580133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373684475, states[0] = -94.654157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387500783, states[0] = 44.715746, states[40]= 0.012043
Saving checkpoint... 
Iteration: 1401299489, states[0] = -94.823126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415364975, states[0] = -94.860909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429320255, states[0] = -94.837828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443282494, states[0] = -94.808537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457230727, states[0] = -94.744879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471463803, states[0] = -94.887198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485963959, states[0] = -94.887215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500411430, states[0] = -47.656851, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1514676478, states[0] = -95.140521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528780065, states[0] = -95.159537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542777554, states[0] = -95.021061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556661777, states[0] = -95.162898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570640170, states[0] = -92.664664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584772922, states[0] = -95.026179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598947902, states[0] = -95.159149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613008822, states[0] = -95.105375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627108708, states[0] = -95.106083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641617768, states[0] = 22.731555, states[40]= 0.014779
Saving checkpoint... 
Iteration: 1655807616, states[0] = -48.704605, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1669804477, states[0] = 34.051391, states[40]= 0.120915
Saving checkpoint... 
Iteration: 1683775624, states[0] = -95.038708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697799296, states[0] = -38.873770, states[40]= 0.000157
Saving checkpoint... 
Iteration: 1711667995, states[0] = -95.019315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725837347, states[0] = -95.150308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739947439, states[0] = -95.162429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754041481, states[0] = -95.155453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768059504, states[0] = -94.990549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782155045, states[0] = -94.959154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795958881, states[0] = -94.987438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809619522, states[0] = -44.352969, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1823632273, states[0] = -57.424103, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1837669951, states[0] = -94.511551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851728398, states[0] = -94.759592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865870927, states[0] = -94.875291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879972676, states[0] = -94.896508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893814556, states[0] = -94.839351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907892713, states[0] = -94.874331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922080409, states[0] = -4.266622, states[40]= 0.003654
Saving checkpoint... 
Iteration: 1936242878, states[0] = -94.764304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950268152, states[0] = -94.794916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964420543, states[0] = -94.879043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978588107, states[0] = -10.408779, states[40]= 0.002319
Saving checkpoint... 
Iteration: 1992728591, states[0] = -94.741473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007011114, states[0] = 25.057341, states[40]= 0.041028
Saving checkpoint... 
Iteration: 2021372811, states[0] = -94.863777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035273613, states[0] = -94.799579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049428259, states[0] = -94.880113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063889617, states[0] = -94.869574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077825648, states[0] = -94.840793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091398068, states[0] = -94.872174, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.767564
 - CaMKt in component CaMK (millimolar): 0.006780
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.820246
 - nass in component intracellular_ions (millimolar): 6.820305
 - ki in component intracellular_ions (millimolar): 145.159243
 - kss in component intracellular_ions (millimolar): 145.159224
 - cansr in component intracellular_ions (millimolar): 1.307158
 - cajsr in component intracellular_ions (millimolar): 1.269872
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003668
 - hf in component INa (dimensionless): 0.877651
 - hs in component INa (dimensionless): 0.877647
 - j in component INa (dimensionless): 0.877618
 - hsp in component INa (dimensionless): 0.721418
 - jp in component INa (dimensionless): 0.877599
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707012
 - hLp in component INaL (dimensionless): 0.449879
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.623268
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.697859
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934759
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001596
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341749
 - xs1 in component IKs (dimensionless): 0.238050
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997372
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:40:32 (480749): called boinc_finish(0)

</stderr_txt>
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