𝕏

Task 54688056

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_990_0
Workunit 25965732
Created 25 Jun 2024, 9:23:53 UTC
Sent 25 Jun 2024, 17:50:50 UTC
Report deadline 28 Jun 2024, 17:50:50 UTC
Received 26 Jun 2024, 19:13:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222349
Run time 9 hours 16 min 46 sec
CPU time 9 hours 11 min 29 sec
Validate state Valid
Credit 49.43
Device peak FLOPS 1.39 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.56 MB
Peak swap size 11.26 MB
Peak disk usage 0.67 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_990.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_990_0_r1941703283_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_990_0_r1941703283_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 112.968540
     * GNaL_b in INaL: 0.008474
     * Gto_b in Ito: 0.069097
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031907
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.168130
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 68.703681
     * GKb_b in IKb: 0.003884
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044204
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 2875539, states[0] = -94.839764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 5770851, states[0] = -94.811032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 8656809, states[0] = -94.784499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 11549989, states[0] = -94.755511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14429697, states[0] = -94.707065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17316684, states[0] = -94.601289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20208175, states[0] = -94.320816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23099848, states[0] = -2.826386, states[40]= 0.004170
Saving checkpoint... 
Iteration: 25978503, states[0] = -94.707042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28868485, states[0] = -94.702871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31761596, states[0] = -94.698440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34656436, states[0] = -94.691638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37550635, states[0] = -94.677756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40451580, states[0] = -94.648339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43338728, states[0] = -94.563751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46222262, states[0] = -94.301633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49114285, states[0] = -12.795591, states[40]= 0.002105
Saving checkpoint... 
Iteration: 52007533, states[0] = 29.732168, states[40]= 0.107327
Saving checkpoint... 
Iteration: 54883624, states[0] = -94.674018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57768986, states[0] = -94.673842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60648635, states[0] = -94.669856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63539639, states[0] = -94.657065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66429436, states[0] = -94.621393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69321090, states[0] = -94.524781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72218141, states[0] = -94.269866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75108467, states[0] = -7.613977, states[40]= 0.003225
Saving checkpoint... 
Iteration: 78001925, states[0] = 47.019683, states[40]= 0.375757
Saving checkpoint... 
Iteration: 80886830, states[0] = -94.664258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83781253, states[0] = -94.665034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86671275, states[0] = -94.662909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89558940, states[0] = -94.652909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92448009, states[0] = -94.623294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95332982, states[0] = -94.534598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98222170, states[0] = -94.279267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101104883, states[0] = -4.754933, states[40]= 0.003891
Saving checkpoint... 
Iteration: 103986312, states[0] = -94.657876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106872759, states[0] = -94.660160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109755600, states[0] = -94.661034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112645971, states[0] = -94.658032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115533834, states[0] = -94.645314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118425573, states[0] = -94.609567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121317041, states[0] = -94.509634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124209040, states[0] = -94.193019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127088696, states[0] = 4.963023, states[40]= 0.005030
Saving checkpoint... 
Iteration: 129976898, states[0] = -94.655782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132867138, states[0] = -94.658105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135749513, states[0] = -94.659015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138633614, states[0] = -94.655451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141523783, states[0] = -94.641622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144406680, states[0] = -94.597184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147299215, states[0] = -94.478952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150188205, states[0] = -83.278831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153077741, states[0] = 10.189319, states[40]= 0.004882
Saving checkpoint... 
Iteration: 155969905, states[0] = -94.654774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158857555, states[0] = -94.657178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161738060, states[0] = -94.657926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164633962, states[0] = -94.654527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167526690, states[0] = -94.641337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170408127, states[0] = -94.597264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173300116, states[0] = -94.479789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176187055, states[0] = -81.311988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179063903, states[0] = 15.835746, states[40]= 0.004255
Saving checkpoint... 
Iteration: 181956683, states[0] = -94.654490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184843357, states[0] = -94.656841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187740289, states[0] = -94.657409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190635080, states[0] = -94.654101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193526104, states[0] = -94.640757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196409170, states[0] = -94.597472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199293030, states[0] = -94.466346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202181299, states[0] = -72.510066, states[40]= 0.000003
Saving checkpoint... 
Iteration: 205071466, states[0] = 12.877762, states[40]= 0.004647
Saving checkpoint... 
Iteration: 207965821, states[0] = -94.653930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210856924, states[0] = -94.656307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213748389, states[0] = -94.657167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216637306, states[0] = -94.653969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219522274, states[0] = -94.639714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222414681, states[0] = -94.600507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225299476, states[0] = -94.478016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228188855, states[0] = -84.131658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231079979, states[0] = 9.212647, states[40]= 0.004944
Saving checkpoint... 
Iteration: 233970848, states[0] = -94.653616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236859993, states[0] = -94.656076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239741820, states[0] = -94.656964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242624523, states[0] = -94.652966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245515701, states[0] = -94.638142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248406874, states[0] = -94.595679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251296579, states[0] = -94.472631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254185474, states[0] = -78.673214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257070832, states[0] = 13.141234, states[40]= 0.004619
Saving checkpoint... 
Iteration: 259957244, states[0] = -94.653843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262839457, states[0] = -94.656306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265728547, states[0] = -94.656742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268618753, states[0] = -94.652439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271499444, states[0] = -94.634113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274389798, states[0] = -94.584042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277274814, states[0] = -94.427759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280162456, states[0] = -51.912967, states[40]= 0.000084
Saving checkpoint... 
Iteration: 283051825, states[0] = 20.084566, states[40]= 0.003479
Saving checkpoint... 
Iteration: 285942204, states[0] = -94.654133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288833111, states[0] = -94.656323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291718191, states[0] = -94.656531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294596206, states[0] = -94.650398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297484476, states[0] = -94.629846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300362435, states[0] = -94.561050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303245058, states[0] = -94.348830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306136414, states[0] = -29.414746, states[40]= 0.001452
Saving checkpoint... 
Iteration: 309029832, states[0] = 26.533302, states[40]= 0.002349
Saving checkpoint... 
Iteration: 311912075, states[0] = -94.654778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314802213, states[0] = -94.656626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317694001, states[0] = -94.655980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320586763, states[0] = -94.649359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323469384, states[0] = -94.624915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326356612, states[0] = -94.555282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329244474, states[0] = -94.347009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332130708, states[0] = -24.946670, states[40]= 0.001671
Saving checkpoint... 
Iteration: 335024689, states[0] = 27.646273, states[40]= 0.002452
Saving checkpoint... 
Iteration: 337906977, states[0] = -94.654841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340794141, states[0] = -94.656641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343681065, states[0] = -94.655553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346566975, states[0] = -94.646900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349446662, states[0] = -94.616093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352337877, states[0] = -94.534475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355227317, states[0] = -94.291584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358114975, states[0] = -12.284188, states[40]= 0.002202
Saving checkpoint... 
Iteration: 361003010, states[0] = 40.226031, states[40]= 0.402593
Saving checkpoint... 
Iteration: 363892091, states[0] = -94.655116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366773482, states[0] = -94.656697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369660646, states[0] = -94.654722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372543549, states[0] = -94.643292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375431634, states[0] = -94.609132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378325283, states[0] = -94.518145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381217761, states[0] = -94.256110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384108596, states[0] = -7.245566, states[40]= 0.003312
Saving checkpoint... 
Iteration: 386989968, states[0] = -94.652735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389879521, states[0] = -94.655328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392769414, states[0] = -94.656661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395660032, states[0] = -94.654651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398542587, states[0] = -94.643083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401436796, states[0] = -94.611574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404325247, states[0] = -94.518051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407215421, states[0] = -94.244948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410100490, states[0] = -1.623701, states[40]= 0.004489
Saving checkpoint... 
Iteration: 412985990, states[0] = -94.652794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415859902, states[0] = -94.655655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418743237, states[0] = -94.656560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421632205, states[0] = -94.653087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424517897, states[0] = -94.638232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427400528, states[0] = -94.591217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430283471, states[0] = -94.446462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433169431, states[0] = -58.790933, states[40]= 0.000027
Saving checkpoint... 
Iteration: 436055288, states[0] = 18.924176, states[40]= 0.003711
Saving checkpoint... 
Iteration: 438946706, states[0] = -94.653741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441834674, states[0] = -94.656021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444723649, states[0] = -94.656331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447609316, states[0] = -94.651329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450504373, states[0] = -94.635029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453394569, states[0] = -94.587120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456286455, states[0] = -94.452594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459173387, states[0] = -62.928868, states[40]= 0.000013
Saving checkpoint... 
Iteration: 462062655, states[0] = 16.311773, states[40]= 0.004183
Saving checkpoint... 
Iteration: 464952300, states[0] = -94.653562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467789257, states[0] = -94.656461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470680107, states[0] = -94.655309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473562232, states[0] = -94.646033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476446431, states[0] = -94.615783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479323397, states[0] = -94.515358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482213069, states[0] = -94.230414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485151906, states[0] = -42.160646, states[40]= 0.000354
Saving checkpoint... 
Iteration: 488026646, states[0] = 27.252944, states[40]= 0.002353
Saving checkpoint... 
Iteration: 490893069, states[0] = -94.654886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493771156, states[0] = -94.656494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496638890, states[0] = -94.653383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499487041, states[0] = -94.630256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502427538, states[0] = -94.606864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505283973, states[0] = -94.447392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508141628, states[0] = -33.561678, states[40]= 0.001023
Saving checkpoint... 
Iteration: 510994515, states[0] = -94.652415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513854423, states[0] = -94.655592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516709842, states[0] = -94.655996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519560996, states[0] = -94.645783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522411203, states[0] = -94.597779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525260585, states[0] = -94.392319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528106910, states[0] = -5.993522, states[40]= 0.003609
Saving checkpoint... 
Iteration: 530946736, states[0] = -94.653592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533844470, states[0] = -94.655724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536701364, states[0] = -94.655790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539551664, states[0] = -94.644350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542402631, states[0] = -94.592408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545264475, states[0] = -94.402337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548115444, states[0] = -12.666434, states[40]= 0.002134
Saving checkpoint... 
Iteration: 550964634, states[0] = -94.653116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553800206, states[0] = -94.656242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556632103, states[0] = -94.652862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559459367, states[0] = -94.620882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562286308, states[0] = -94.452122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565092602, states[0] = 2.980860, states[40]= 0.004968
Saving checkpoint... 
Iteration: 567958616, states[0] = -94.653239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570813669, states[0] = -94.656082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573627232, states[0] = -94.652508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576432661, states[0] = -94.609309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579249820, states[0] = -94.362452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582098923, states[0] = -0.649262, states[40]= 0.004632
Saving checkpoint... 
Iteration: 584951116, states[0] = -94.653397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587810205, states[0] = -94.656092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590670474, states[0] = -94.654771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593549915, states[0] = -94.643985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596420629, states[0] = -94.603053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599290026, states[0] = -94.459510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602157849, states[0] = -47.541815, states[40]= 0.000164
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Iteration: 821096932, states[0] = 0.542805, states[40]= 0.004776
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Iteration: 878139826, states[0] = -32.116997, states[40]= 0.001177
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Iteration: 881008032, states[0] = 29.611381, states[40]= 0.090912
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Iteration: 883875333, states[0] = -94.654614, states[40]= 0.000000
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Iteration: 1104362158, states[0] = -94.559462, states[40]= 0.000000
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Iteration: 1110083737, states[0] = 7.471525, states[40]= 0.005014
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Iteration: 1124359899, states[0] = -94.557246, states[40]= 0.000000
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Iteration: 1127188678, states[0] = -83.818613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130010523, states[0] = 29.087387, states[40]= 0.040479


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_990.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_990_0_r1941703283_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_990_0_r1941703283_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 112.968540
     * GNaL_b in INaL: 0.008474
     * Gto_b in Ito: 0.069097
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031907
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.168130
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 68.703681
     * GKb_b in IKb: 0.003884
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044204
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1130010523
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 29.087387 (After loading)
 - states[40]: 0.040479 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1132668283, states[0] = -94.653814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135348915, states[0] = -94.545895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138020609, states[0] = 28.322432, states[40]= 0.003306
Saving checkpoint... 
Iteration: 1140696036, states[0] = -94.654693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143375479, states[0] = -94.571347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146059504, states[0] = 17.455169, states[40]= 0.003987
Saving checkpoint... 
Iteration: 1148753939, states[0] = -94.655434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151445328, states[0] = -94.614220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154144434, states[0] = -35.838423, states[40]= 0.000797
Saving checkpoint... 
Iteration: 1156853193, states[0] = -94.654579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159565131, states[0] = -94.645334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162271615, states[0] = -94.418825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164976917, states[0] = -94.651817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167676932, states[0] = -94.654081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170394052, states[0] = -94.585601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173084485, states[0] = 7.113984, states[40]= 0.005023
Saving checkpoint... 
Iteration: 1175771338, states[0] = -94.655397, states[40]= 0.000000
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Iteration: 1178450377, states[0] = -94.616316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181136950, states[0] = -29.834894, states[40]= 0.001413
Saving checkpoint... 
Iteration: 1183831766, states[0] = -94.654869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186529168, states[0] = -94.639345, states[40]= 0.000000
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Iteration: 1189226055, states[0] = -94.285872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191921633, states[0] = -94.653127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194625520, states[0] = -94.651390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197317111, states[0] = -94.505096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200026320, states[0] = 27.321568, states[40]= 0.002363
Saving checkpoint... 
Iteration: 1202742704, states[0] = -94.655296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205454491, states[0] = -94.617944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208147215, states[0] = -38.140444, states[40]= 0.000602
Saving checkpoint... 
Iteration: 1210834688, states[0] = -94.654784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213525701, states[0] = -94.638609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216224577, states[0] = -94.280674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218911123, states[0] = -94.653323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221612758, states[0] = -94.650373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224310130, states[0] = -94.494246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227012715, states[0] = 28.965246, states[40]= 0.020323
Saving checkpoint... 
Iteration: 1229723491, states[0] = -94.655067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232427695, states[0] = -94.605768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235149916, states[0] = -40.431058, states[40]= 0.000448
Saving checkpoint... 
Iteration: 1237853269, states[0] = -94.654448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240547350, states[0] = -94.642529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243239235, states[0] = -94.329291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245921601, states[0] = -94.653041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248608143, states[0] = -94.649941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251291078, states[0] = -94.460509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253987027, states[0] = -94.651414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256687835, states[0] = -94.654286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259382920, states[0] = -94.577195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262088446, states[0] = 5.158878, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1264789403, states[0] = -94.655179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267490976, states[0] = -94.630155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270200716, states[0] = -93.668386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272911025, states[0] = -94.653238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275619954, states[0] = -94.650853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278342958, states[0] = -94.538986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281068356, states[0] = 14.135203, states[40]= 0.004500
Saving checkpoint... 
Iteration: 1283789637, states[0] = -94.655147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286505675, states[0] = -94.634006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288494373, states[0] = -94.631067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290334851, states[0] = -94.529224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292240281, states[0] = -94.332500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294234679, states[0] = -94.314600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296286790, states[0] = -94.451912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298259532, states[0] = -94.388276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300205230, states[0] = -94.078938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302272895, states[0] = -94.421606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304430290, states[0] = -94.606965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306866938, states[0] = -94.654094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309521230, states[0] = -94.637527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312127639, states[0] = -22.541063, states[40]= 0.001623
Saving checkpoint... 
Iteration: 1314801478, states[0] = -94.655008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317483535, states[0] = -94.627894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320170960, states[0] = -60.358621, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1322856746, states[0] = -94.654251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325547899, states[0] = -94.642482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328225475, states[0] = -94.283632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330918638, states[0] = -94.652972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333610594, states[0] = -94.650013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336309617, states[0] = -94.493240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339007504, states[0] = 29.864284, states[40]= 0.108028
Saving checkpoint... 
Iteration: 1341708938, states[0] = -94.654653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344410516, states[0] = -94.596043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347120240, states[0] = -16.600026, states[40]= 0.001643
Saving checkpoint... 
Iteration: 1349828126, states[0] = -94.654652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352505518, states[0] = -94.633861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355131138, states[0] = -25.280500, states[40]= 0.001670
Saving checkpoint... 
Iteration: 1357720649, states[0] = -94.654822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360285048, states[0] = -94.448238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362815910, states[0] = -94.654784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365334301, states[0] = -94.528413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367867764, states[0] = -94.653980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370369667, states[0] = -94.565957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372876774, states[0] = -94.653800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375382081, states[0] = -94.576349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377911452, states[0] = -94.653060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380416372, states[0] = -94.599413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382932346, states[0] = -94.652569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385430431, states[0] = -94.606905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387975230, states[0] = -94.651501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390498967, states[0] = -94.632134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393022542, states[0] = 28.028873, states[40]= 0.002739
Saving checkpoint... 
Iteration: 1395587988, states[0] = -94.647749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398204950, states[0] = -94.065724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400819273, states[0] = -94.654683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403450965, states[0] = -94.616197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406091160, states[0] = 3.753219, states[40]= 0.005002
Saving checkpoint... 
Iteration: 1408702260, states[0] = -94.654409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411320051, states[0] = -94.509078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413891247, states[0] = -94.653441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416490546, states[0] = -94.629793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419115275, states[0] = -12.527287, states[40]= 0.002158
Saving checkpoint... 
Iteration: 1421731038, states[0] = -94.654847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424402804, states[0] = -94.591099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427057763, states[0] = 18.070003, states[40]= 0.003875
Saving checkpoint... 
Iteration: 1429758280, states[0] = -94.654992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432440117, states[0] = -94.611450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435125552, states[0] = -20.890334, states[40]= 0.001571
Saving checkpoint... 
Iteration: 1437814550, states[0] = -94.654679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440511717, states[0] = -94.635204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443215435, states[0] = -94.243314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445926125, states[0] = -94.652614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448632346, states[0] = -94.651444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451338760, states[0] = -94.533759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454044382, states[0] = 22.460270, states[40]= 0.002998
Saving checkpoint... 
Iteration: 1456755774, states[0] = -94.654944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459466730, states[0] = -94.622142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462171286, states[0] = -60.697229, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1464875210, states[0] = -94.653682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467593390, states[0] = -94.648200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470303020, states[0] = -94.482029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473007856, states[0] = 29.687287, states[40]= 0.096293
Saving checkpoint... 
Iteration: 1475720903, states[0] = -94.654636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478438100, states[0] = -94.610448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481138819, states[0] = -31.314341, states[40]= 0.001263
Saving checkpoint... 
Iteration: 1483845301, states[0] = -94.654184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486479967, states[0] = -94.626521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489101050, states[0] = -1.979057, states[40]= 0.004432
Saving checkpoint... 
Iteration: 1491701496, states[0] = -94.654258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494275011, states[0] = -94.426184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496807176, states[0] = -94.654662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499288733, states[0] = -94.455491, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.526619
 - CaMKt in component CaMK (millimolar): 0.004214
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.552540
 - nass in component intracellular_ions (millimolar): 6.552625
 - ki in component intracellular_ions (millimolar): 145.361793
 - kss in component intracellular_ions (millimolar): 145.361778
 - cansr in component intracellular_ions (millimolar): 1.588683
 - cajsr in component intracellular_ions (millimolar): 1.587839
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003758
 - hf in component INa (dimensionless): 0.873335
 - hs in component INa (dimensionless): 0.873336
 - j in component INa (dimensionless): 0.873342
 - hsp in component INa (dimensionless): 0.713424
 - jp in component INa (dimensionless): 0.873345
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719006
 - hLp in component INaL (dimensionless): 0.510375
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.890361
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.930287
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.974016
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002721
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.101886
 - xs1 in component IKs (dimensionless): 0.129037
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997434
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:06:32 (963521): called boinc_finish(0)

</stderr_txt>
]]>


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