𝕏

Task 54678585

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_978_1
Workunit 25960997
Created 25 Jun 2024, 9:19:05 UTC
Sent 25 Jun 2024, 16:38:41 UTC
Report deadline 29 Jun 2024, 2:14:41 UTC
Received 29 Jun 2024, 0:48:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 52 min 55 sec
CPU time 2 hours 26 min 25 sec
Validate state Valid
Credit 61.18
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.29 MB
Peak swap size 5.45 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_978.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_978_1_r1444302695_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_978_1_r1444302695_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.818027
     * GNaL_b in INaL: 0.005395
     * Gto_b in Ito: 0.074601
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033546
     * GKs_b in IKs: 0.001772
     * GK1_b in IK1: 0.154275
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 65.096916
     * GKb_b in IKb: 0.003885
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035768
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11601008, states[0] = -29.476377, states[40]= 0.000442
Saving checkpoint... 
Iteration: 25058091, states[0] = 6.274722, states[40]= 0.004967
Saving checkpoint... 
Iteration: 37971758, states[0] = -95.142367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50588594, states[0] = -14.310576, states[40]= 0.001616
Saving checkpoint... 
Iteration: 62890974, states[0] = -95.108118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75787299, states[0] = -95.046574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87872710, states[0] = -95.094143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101483900, states[0] = -95.118309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112263141, states[0] = -95.015892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125122834, states[0] = -48.959196, states[40]= 0.000032
Saving checkpoint... 
Iteration: 138493793, states[0] = -95.116353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152086233, states[0] = -10.995006, states[40]= 0.002201
Saving checkpoint... 
Iteration: 164710137, states[0] = -94.934263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178138893, states[0] = -68.049741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191322161, states[0] = -95.062334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204850638, states[0] = -95.077637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218209929, states[0] = -94.933156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230047438, states[0] = 11.825754, states[40]= 0.005236
Saving checkpoint... 
Iteration: 241241778, states[0] = -94.985381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253670628, states[0] = -94.814214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267104734, states[0] = -29.533408, states[40]= 0.000465
Saving checkpoint... 
Iteration: 280547450, states[0] = 11.822430, states[40]= 0.005236
Saving checkpoint... 
Iteration: 293848015, states[0] = -95.076077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307272331, states[0] = -95.021882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320742234, states[0] = -94.985878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334090932, states[0] = -15.512908, states[40]= 0.001434
Saving checkpoint... 
Iteration: 347426904, states[0] = -95.102944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360933845, states[0] = -95.104488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374370514, states[0] = -95.085800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387744420, states[0] = -94.988834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400759927, states[0] = -95.008311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414168078, states[0] = -94.769187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427347672, states[0] = -95.075810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440737722, states[0] = -94.979378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454205940, states[0] = -94.925091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467277618, states[0] = -95.027027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480707941, states[0] = -94.928986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494038925, states[0] = 15.292803, states[40]= 0.005591
Saving checkpoint... 
Iteration: 507483487, states[0] = -95.113023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520981587, states[0] = -95.112753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534470472, states[0] = -95.111117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547948485, states[0] = -95.107344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561372974, states[0] = -95.086638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574828257, states[0] = -95.065373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588220685, states[0] = -94.952251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601692091, states[0] = -94.896172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614834046, states[0] = -95.068641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628339859, states[0] = -95.071758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641765357, states[0] = -95.014291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655167038, states[0] = -94.739968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668534669, states[0] = 16.920294, states[40]= 0.005913
Saving checkpoint... 
Iteration: 682010578, states[0] = 24.083680, states[40]= 0.046324
Saving checkpoint... 
Iteration: 695528936, states[0] = 18.947992, states[40]= 0.006654
Saving checkpoint... 
Iteration: 708803667, states[0] = -95.049041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722018445, states[0] = 21.994605, states[40]= 0.012013
Saving checkpoint... 
Iteration: 735513295, states[0] = 23.245264, states[40]= 0.026183
Saving checkpoint... 
Iteration: 748727485, states[0] = -94.963501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761861066, states[0] = -95.081712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774913289, states[0] = -95.099335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788361438, states[0] = -95.081855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801533073, states[0] = 17.505975, states[40]= 0.006075
Saving checkpoint... 
Iteration: 815021970, states[0] = 21.075546, states[40]= 0.008906
Saving checkpoint... 
Iteration: 827864329, states[0] = -95.083046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840372272, states[0] = -95.086207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853809895, states[0] = -95.053452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867324340, states[0] = -95.062868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879751513, states[0] = -94.997843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892595737, states[0] = -20.369894, states[40]= 0.000942
Saving checkpoint... 
Iteration: 906058834, states[0] = 6.816425, states[40]= 0.004976
Saving checkpoint... 
Iteration: 917774982, states[0] = -95.024179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929159856, states[0] = -93.983406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942036055, states[0] = 16.400203, states[40]= 0.005793
Saving checkpoint... 
Iteration: 955297906, states[0] = -95.044483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965810769, states[0] = -95.053995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979321703, states[0] = -95.061180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992760139, states[0] = -95.008209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006043870, states[0] = 13.307096, states[40]= 0.005352
Saving checkpoint... 
Iteration: 1019410772, states[0] = -95.098525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032893375, states[0] = -95.093451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046394760, states[0] = -95.093877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059858939, states[0] = -95.080621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073338674, states[0] = -95.070875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086801702, states[0] = -95.047343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100159865, states[0] = -93.985459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113416234, states[0] = -95.099900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124810923, states[0] = -95.054009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138229629, states[0] = -94.966695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151034346, states[0] = 17.040098, states[40]= 0.005944
Saving checkpoint... 
Iteration: 1164503606, states[0] = 35.279033, states[40]= 0.141751
Saving checkpoint... 
Iteration: 1178021317, states[0] = 21.253592, states[40]= 0.009310
Saving checkpoint... 
Iteration: 1191459840, states[0] = -95.109010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204835319, states[0] = -95.068996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218283721, states[0] = -95.032312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231728741, states[0] = -94.965231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245240039, states[0] = -94.982239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258654833, states[0] = -91.470657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272136337, states[0] = -64.657588, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1285728672, states[0] = -94.965090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299207520, states[0] = -94.927688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312616140, states[0] = -41.397393, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1326115778, states[0] = -41.009235, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1339388329, states[0] = -95.091643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352896857, states[0] = -95.094345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366225865, states[0] = -94.960505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379632064, states[0] = -59.428179, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1392981764, states[0] = -95.112271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406394351, states[0] = -95.093540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419771278, states[0] = -95.020135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432942180, states[0] = -95.105600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446421315, states[0] = -95.100972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459652566, states[0] = -89.102020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473069629, states[0] = 1.333387, states[40]= 0.004539
Saving checkpoint... 
Iteration: 1486216388, states[0] = -94.944163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499590933, states[0] = -15.512830, states[40]= 0.001434
Saving checkpoint... 
Iteration: 1512698829, states[0] = -39.170154, states[40]= 0.000140
Saving checkpoint... 
Iteration: 1526107028, states[0] = 27.663182, states[40]= 0.093264
Saving checkpoint... 
Iteration: 1539453153, states[0] = -95.147314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552824311, states[0] = 19.576611, states[40]= 0.009001
Saving checkpoint... 
Iteration: 1566234372, states[0] = -95.341078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579634722, states[0] = -92.453651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593057818, states[0] = 1.578441, states[40]= 0.005129
Saving checkpoint... 
Iteration: 1604466721, states[0] = -5.529937, states[40]= 0.003777
Saving checkpoint... 
Iteration: 1617697917, states[0] = -41.094910, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1631092549, states[0] = -95.405824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644474410, states[0] = -95.241588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656575302, states[0] = -95.393596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669677546, states[0] = -95.249727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682800772, states[0] = -44.690296, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1693086401, states[0] = -95.270203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706414298, states[0] = 23.130182, states[40]= 0.023314
Saving checkpoint... 
Iteration: 1719819553, states[0] = -95.331020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733021160, states[0] = -95.333454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746340502, states[0] = 11.742662, states[40]= 0.006263
Saving checkpoint... 
Iteration: 1759693157, states[0] = -95.284567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773032464, states[0] = 15.786343, states[40]= 0.007067
Saving checkpoint... 
Iteration: 1785870860, states[0] = -95.390385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799329528, states[0] = -95.345345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812592614, states[0] = -20.304552, states[40]= 0.000964
Saving checkpoint... 
Iteration: 1825932033, states[0] = -95.139927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838926998, states[0] = -95.127664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852304631, states[0] = -95.066716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865664494, states[0] = -94.679637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878491446, states[0] = -95.121612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891831348, states[0] = -95.072126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905175217, states[0] = -94.853544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918452973, states[0] = -95.110065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931793608, states[0] = -95.042302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945107482, states[0] = -32.423924, states[40]= 0.000341
Saving checkpoint... 
Iteration: 1958471985, states[0] = -95.111365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971845647, states[0] = -95.074485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985205795, states[0] = -94.924291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998550669, states[0] = 10.451693, states[40]= 0.005156
Saving checkpoint... 
Iteration: 2011881356, states[0] = -95.089021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025219822, states[0] = -94.950006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038664610, states[0] = -94.627482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051779179, states[0] = -95.027614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065165552, states[0] = -94.679919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078550632, states[0] = 10.472129, states[40]= 0.005157
Saving checkpoint... 
Iteration: 2091766090, states[0] = -95.014214, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.990025
 - CaMKt in component CaMK (millimolar): 0.006751
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.648364
 - nass in component intracellular_ions (millimolar): 6.648425
 - ki in component intracellular_ions (millimolar): 145.331043
 - kss in component intracellular_ions (millimolar): 145.331022
 - cansr in component intracellular_ions (millimolar): 1.305826
 - cajsr in component intracellular_ions (millimolar): 1.268742
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003586
 - hf in component INa (dimensionless): 0.881522
 - hs in component INa (dimensionless): 0.881518
 - j in component INa (dimensionless): 0.881489
 - hsp in component INa (dimensionless): 0.728704
 - jp in component INa (dimensionless): 0.881470
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713867
 - hLp in component INaL (dimensionless): 0.459616
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.629195
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.705430
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938295
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001589
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328529
 - xs1 in component IKs (dimensionless): 0.231561
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997314
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:47:41 (16460): called boinc_finish(0)

</stderr_txt>
]]>