𝕏

Task 54663268

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_160_1
Workunit 25953344
Created 25 Jun 2024, 9:11:09 UTC
Sent 25 Jun 2024, 14:51:01 UTC
Report deadline 28 Jun 2024, 14:51:01 UTC
Received 1 Jul 2024, 14:21:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232753
Run time 2 hours 15 min 41 sec
CPU time 2 hours 12 min 56 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.81 MB
Peak swap size 32.10 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_160.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_160_1_r263457257_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_160_1_r263457257_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.796894
     * GNaL_b in INaL: 0.006436
     * Gto_b in Ito: 0.087925
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033070
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.150236
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 61.584409
     * GKb_b in IKb: 0.003788
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032874
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11591240, states[0] = -94.561124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23024995, states[0] = 25.725395, states[40]= 0.001971
Saving checkpoint... 
Iteration: 34485063, states[0] = -94.479313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45851222, states[0] = -94.501454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57236177, states[0] = -94.106802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68747874, states[0] = -94.496983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80229833, states[0] = -94.077751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92798478, states[0] = -94.494736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103938708, states[0] = -94.491068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115220788, states[0] = -94.038131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126442921, states[0] = -94.444706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137726028, states[0] = -94.493328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149019937, states[0] = 26.526281, states[40]= 0.002848
Saving checkpoint... 
Iteration: 160462100, states[0] = -94.453281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171768644, states[0] = -94.493083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183202954, states[0] = -93.851694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194637290, states[0] = -94.489403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206129750, states[0] = -29.067710, states[40]= 0.001240
Saving checkpoint... 
Iteration: 217397450, states[0] = -94.414315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228773402, states[0] = -94.492753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240128161, states[0] = -27.707931, states[40]= 0.001316
Saving checkpoint... 
Iteration: 251380460, states[0] = -94.399490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262749587, states[0] = -94.492671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274127919, states[0] = -27.500220, states[40]= 0.001326
Saving checkpoint... 
Iteration: 285519597, states[0] = -94.471941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296884674, states[0] = -94.490711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308261994, states[0] = -94.187941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319631145, states[0] = -94.488568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331118702, states[0] = -19.574308, states[40]= 0.001367
Saving checkpoint... 
Iteration: 342372864, states[0] = -94.391882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353811831, states[0] = -94.492072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365224227, states[0] = -94.051242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376660665, states[0] = -94.490292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388083338, states[0] = 6.175297, states[40]= 0.004478
Saving checkpoint... 
Iteration: 399531206, states[0] = -94.474454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410847567, states[0] = -94.491327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422277855, states[0] = -94.232483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433590035, states[0] = -94.484324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445040692, states[0] = 22.304353, states[40]= 0.001921
Saving checkpoint... 
Iteration: 456387390, states[0] = -94.405332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467808944, states[0] = -94.491879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479110440, states[0] = -12.254350, states[40]= 0.002104
Saving checkpoint... 
Iteration: 490410771, states[0] = -94.423664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501705034, states[0] = -94.491619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512957342, states[0] = -94.488216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524244824, states[0] = -94.130670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535601706, states[0] = -94.485455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546924619, states[0] = -94.489115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558234845, states[0] = -94.093493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569492722, states[0] = -94.463654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580914940, states[0] = -94.489320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592170064, states[0] = -66.646055, states[40]= 0.000006
Saving checkpoint... 
Iteration: 603359722, states[0] = -94.377203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613670991, states[0] = -94.490294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624867138, states[0] = -94.490464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635940016, states[0] = -94.488488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646436343, states[0] = -94.439320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655061845, states[0] = 15.407244, states[40]= 0.003302


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_160.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_160_1_r263457257_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_2000-conf_160_1_r263457257_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.796894
     * GNaL_b in INaL: 0.006436
     * Gto_b in Ito: 0.087925
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033070
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.150236
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 61.584409
     * GKb_b in IKb: 0.003788
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032874
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 655061845
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 15.407244 (After loading)
 - states[40]: 0.003302 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 670032563, states[0] = 24.432090, states[40]= 0.001583
Saving checkpoint... 
Iteration: 682442155, states[0] = -94.442372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694510275, states[0] = -94.468653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706461849, states[0] = -94.451729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718609558, states[0] = -94.485892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730849772, states[0] = -94.490635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743137020, states[0] = -35.328156, states[40]= 0.000734
Saving checkpoint... 
Iteration: 755411508, states[0] = -94.423644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767763479, states[0] = -94.491637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779864697, states[0] = -94.490208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792199351, states[0] = -93.654034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804503299, states[0] = -94.466448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816787823, states[0] = -94.491411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829644928, states[0] = -94.488486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841857164, states[0] = -94.490252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854429123, states[0] = -94.434772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866571051, states[0] = -94.480876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878649693, states[0] = -94.488678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891203107, states[0] = -93.854625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903234111, states[0] = -94.089940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915430974, states[0] = -94.435734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928070836, states[0] = 11.881570, states[40]= 0.003905
Saving checkpoint... 
Iteration: 940289743, states[0] = -94.260607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952556115, states[0] = -94.478283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964730260, states[0] = -94.491098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977024165, states[0] = 26.057852, states[40]= 0.001687
Saving checkpoint... 
Iteration: 989334908, states[0] = -94.344201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001696778, states[0] = -94.490406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013881310, states[0] = -94.489338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026087952, states[0] = 3.764899, states[40]= 0.004543
Saving checkpoint... 
Iteration: 1038364511, states[0] = -94.381686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050785637, states[0] = -94.490957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063086344, states[0] = 4.627817, states[40]= 0.004533
Saving checkpoint... 
Iteration: 1075308798, states[0] = -94.300339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086783562, states[0] = -94.490901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098042175, states[0] = 21.878093, states[40]= 0.001999
Saving checkpoint... 
Iteration: 1109447180, states[0] = -94.444076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120539812, states[0] = -94.474847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131741618, states[0] = -94.490856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142937681, states[0] = -94.487533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153966734, states[0] = -94.486635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165091553, states[0] = 1.731288, states[40]= 0.004500
Saving checkpoint... 
Iteration: 1176286499, states[0] = -94.252508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187419083, states[0] = -94.427873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198507743, states[0] = -94.466931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209758621, states[0] = -94.490749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220871162, states[0] = -94.489167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232124899, states[0] = -24.921809, states[40]= 0.001384
Saving checkpoint... 
Iteration: 1243301592, states[0] = -94.285771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254473376, states[0] = -94.455372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265660793, states[0] = -94.488503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276635716, states[0] = -94.486966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287381105, states[0] = -94.397961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298311381, states[0] = -94.304737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309449664, states[0] = -94.444897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320401359, states[0] = -94.415064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331297943, states[0] = -94.277980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342295091, states[0] = -94.271809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353365804, states[0] = -94.382454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364374908, states[0] = -94.391850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375290832, states[0] = -94.262221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386437515, states[0] = -94.438468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397386181, states[0] = -94.402358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408400933, states[0] = -94.414558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419463706, states[0] = -94.451089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430316798, states[0] = -94.314241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441246754, states[0] = -94.135621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452135915, states[0] = -34.365537, states[40]= 0.000812
Saving checkpoint... 
Iteration: 1463064803, states[0] = 14.293311, states[40]= 0.003510
Saving checkpoint... 
Iteration: 1473934469, states[0] = -94.486959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484848482, states[0] = -94.489140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495854423, states[0] = -94.488992, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.360834
 - CaMKt in component CaMK (millimolar): 0.004354
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.778431
 - nass in component intracellular_ions (millimolar): 6.778519
 - ki in component intracellular_ions (millimolar): 145.125868
 - kss in component intracellular_ions (millimolar): 145.125852
 - cansr in component intracellular_ions (millimolar): 1.622922
 - cajsr in component intracellular_ions (millimolar): 1.622367
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003822
 - hf in component INa (dimensionless): 0.870291
 - hs in component INa (dimensionless): 0.870292
 - j in component INa (dimensionless): 0.870299
 - hsp in component INa (dimensionless): 0.707823
 - jp in component INa (dimensionless): 0.870303
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714534
 - hLp in component INaL (dimensionless): 0.505552
 - a in component Ito (dimensionless): 0.000647
 - iF in component Ito (dimensionless): 0.999857
 - iS in component Ito (dimensionless): 0.891533
 - ap in component Ito (dimensionless): 0.000329
 - iFp in component Ito (dimensionless): 0.999857
 - iSp in component Ito (dimensionless): 0.931223
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975889
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002904
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.098919
 - xs1 in component IKs (dimensionless): 0.123985
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997476
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:21:00 (888): called boinc_finish(0)

</stderr_txt>
]]>


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