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Task 54662581

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_5000-conf_759_0
Workunit 25953001
Created 25 Jun 2024, 9:10:48 UTC
Sent 25 Jun 2024, 14:49:55 UTC
Report deadline 28 Jun 2024, 14:49:55 UTC
Received 25 Jun 2024, 18:28:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234818
Run time 1 hours 9 min 52 sec
CPU time 48 min 22 sec
Validate state Valid
Credit 44.14
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.80 MB
Peak swap size 391.84 GB
Peak disk usage 1.55 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_5000-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_5000-conf_759_0_r1051545509_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Coppini_5000-conf_759_0_r1051545509_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 99.923445
     * GNaL_b in INaL: 0.006383
     * Gto_b in Ito: 0.068648
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031935
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.167531
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 66.294535
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036071
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 19023284, states[0] = -94.658735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43623790, states[0] = -94.596607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77563795, states[0] = 16.355915, states[40]= 0.003815
Saving checkpoint... 
Iteration: 105880320, states[0] = -94.564649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131981801, states[0] = -94.545457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158773322, states[0] = -94.552013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180868480, states[0] = -94.558024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191618121, states[0] = -94.545687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203276808, states[0] = -94.557488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216110703, states[0] = -94.553302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233584932, states[0] = -94.553586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254114963, states[0] = -94.544868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279909165, states[0] = -94.538485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318819004, states[0] = -94.548882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355336475, states[0] = -94.412074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382019500, states[0] = -94.540681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404664423, states[0] = -94.539655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432150507, states[0] = -94.539722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466553581, states[0] = -94.545245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504701677, states[0] = -94.539346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539360037, states[0] = -94.541873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579172069, states[0] = -94.543737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615365590, states[0] = -94.446757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633678495, states[0] = -94.551129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645053499, states[0] = 20.102581, states[40]= 0.003177
Saving checkpoint... 
Iteration: 652171275, states[0] = -94.539434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660464283, states[0] = -94.514026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669667959, states[0] = -94.539443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683597353, states[0] = -94.552645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704822877, states[0] = -94.538507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727966012, states[0] = -94.514703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753188647, states[0] = -94.554014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776699004, states[0] = -94.543304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796195049, states[0] = -94.550707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812356808, states[0] = -94.538253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831732516, states[0] = -94.542909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855713809, states[0] = -94.554944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889137820, states[0] = -94.543917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919146834, states[0] = -94.543792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945644314, states[0] = -94.551172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970761701, states[0] = -94.555981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000755796, states[0] = -94.555869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031387557, states[0] = -94.547226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068691681, states[0] = -94.550583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103353059, states[0] = -94.556151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131562498, states[0] = -94.544673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150380655, states[0] = -94.460992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175422482, states[0] = -94.492286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206283479, states[0] = -94.548829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240854777, states[0] = -94.556046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275576292, states[0] = -94.543358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296068742, states[0] = -94.552774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315722928, states[0] = -94.554913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340688689, states[0] = -94.553613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374715694, states[0] = -94.538662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406607228, states[0] = -94.543927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447358505, states[0] = -94.537808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481734709, states[0] = -94.542440, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.413058
 - CaMKt in component CaMK (millimolar): 0.001138
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.375522
 - nass in component intracellular_ions (millimolar): 6.375608
 - ki in component intracellular_ions (millimolar): 145.547729
 - kss in component intracellular_ions (millimolar): 145.547719
 - cansr in component intracellular_ions (millimolar): 1.576732
 - cajsr in component intracellular_ions (millimolar): 1.576729
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003802
 - hf in component INa (dimensionless): 0.871256
 - hs in component INa (dimensionless): 0.871256
 - j in component INa (dimensionless): 0.871257
 - hsp in component INa (dimensionless): 0.709587
 - jp in component INa (dimensionless): 0.871257
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.716092
 - hLp in component INaL (dimensionless): 0.524201
 - a in component Ito (dimensionless): 0.000644
 - iF in component Ito (dimensionless): 0.999858
 - iS in component Ito (dimensionless): 0.997779
 - ap in component Ito (dimensionless): 0.000328
 - iFp in component Ito (dimensionless): 0.999858
 - iSp in component Ito (dimensionless): 0.999268
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998860
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003083
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001775
 - xs1 in component IKs (dimensionless): 0.022656
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997463
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:26:21 (39136): called boinc_finish(0)

</stderr_txt>
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