Task 54657212
Name | HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0 |
Workunit | 25950317 |
Created | 25 Jun 2024, 9:08:00 UTC |
Sent | 25 Jun 2024, 14:06:07 UTC |
Report deadline | 28 Jun 2024, 23:42:07 UTC |
Received | 1 Jul 2024, 12:57:30 UTC |
Server state | Over |
Outcome | Success |
Client state | Done |
Exit status | 0 (0x00000000) |
Computer ID | 239016 |
Run time | 2 hours 7 min 22 sec |
CPU time | 1 hours 35 min 6 sec |
Validate state | Valid |
Credit | 64.10 |
Device peak FLOPS | 4.73 GFLOPS |
Application version | Human ventricular cell models optimization v0.02 windows_x86_64 |
Peak working set size | 10.76 MB |
Peak swap size | 5.32 MB |
Peak disk usage | 0.33 MB |
Stderr output
<core_client_version>8.0.2</core_client_version> <![CDATA[ <stderr_txt> * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 141084671 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -4.706391 (After loading) - states[40]: 0.003508 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 157445284, states[0] = -95.084954, states[40]= 0.000000 Saving checkpoint... Iteration: 174336878, states[0] = -95.052016, states[40]= 0.000000 Saving checkpoint... Iteration: 190169076, states[0] = -94.548910, states[40]= 0.000000 Saving checkpoint... Iteration: 205658632, states[0] = -88.071802, states[40]= 0.000000 Saving checkpoint... Iteration: 221091155, states[0] = -9.786201, states[40]= 0.002410 Saving checkpoint... Iteration: 236077069, states[0] = 0.185967, states[40]= 0.004354 Saving checkpoint... Iteration: 250788719, states[0] = -95.021789, states[40]= 0.000000 Saving checkpoint... Iteration: 266779073, states[0] = -95.013826, states[40]= 0.000000 Saving checkpoint... Iteration: 280623327, states[0] = -40.117916, states[40]= 0.000135 Saving checkpoint... Iteration: 296373158, states[0] = -95.066492, states[40]= 0.000000 Saving checkpoint... Iteration: 311501083, states[0] = 47.854003, states[40]= 0.034913 Saving checkpoint... Iteration: 326234562, states[0] = -94.965010, states[40]= 0.000000 Saving checkpoint... Iteration: 341239028, states[0] = -94.970947, states[40]= 0.000000 Saving checkpoint... Iteration: 357299013, states[0] = -95.029350, states[40]= 0.000000 Saving checkpoint... Iteration: 372063318, states[0] = 7.063074, states[40]= 0.004951 Saving checkpoint... Iteration: 387944208, states[0] = -95.084148, states[40]= 0.000000 Saving checkpoint... Iteration: 403070309, states[0] = 3.778811, states[40]= 0.004739 Saving checkpoint... Iteration: 418600381, states[0] = -18.180084, states[40]= 0.001131 Saving checkpoint... Iteration: 430574287, states[0] = 1.729389, states[40]= 0.004543 Saving checkpoint... Iteration: 434461923, states[0] = -95.086985, states[40]= 0.000000 Saving checkpoint... Iteration: 441060106, states[0] = 8.474804, states[40]= 0.005015 Saving checkpoint... Iteration: 444135721, states[0] = -53.803951, states[40]= 0.000016 Saving checkpoint... Iteration: 447060354, states[0] = 8.367535, states[40]= 0.005011 Saving checkpoint... Iteration: 448406368, states[0] = -95.076142, states[40]= 0.000000 Saving checkpoint... Iteration: 450421247, states[0] = -95.079614, states[40]= 0.000000 Saving checkpoint... Iteration: 452569929, states[0] = 3.966651, states[40]= 0.004754 Saving checkpoint... Iteration: 455886802, states[0] = -95.070766, states[40]= 0.000000 Saving checkpoint... Iteration: 457705976, states[0] = -94.920344, states[40]= 0.000000 Saving checkpoint... Iteration: 458776822, states[0] = -95.011721, states[40]= 0.000000 Saving checkpoint... Iteration: 461302821, states[0] = -95.031923, states[40]= 0.000000 Saving checkpoint... Iteration: 463639526, states[0] = -58.371509, states[40]= 0.000008 Saving checkpoint... Iteration: 464728018, states[0] = -94.955721, states[40]= 0.000000 Saving checkpoint... Iteration: 472989700, states[0] = -95.090593, states[40]= 0.000000 Saving checkpoint... Iteration: 488986950, states[0] = -95.090265, states[40]= 0.000000 Saving checkpoint... Iteration: 505162148, states[0] = -92.120201, states[40]= 0.000000 Saving checkpoint... Iteration: 518249043, states[0] = -94.983245, states[40]= 0.000000 Saving checkpoint... Iteration: 534419723, states[0] = -95.079230, states[40]= 0.000000 Saving checkpoint... Iteration: 549965200, states[0] = -95.087396, states[40]= 0.000000 Saving checkpoint... Iteration: 565536411, states[0] = 17.858093, states[40]= 0.005717 Saving checkpoint... Iteration: 581189673, states[0] = -94.889915, states[40]= 0.000000 Saving checkpoint... Iteration: 596845915, states[0] = -95.055660, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 596845915 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.055660 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 614102260, states[0] = -19.941959, states[40]= 0.000995 Saving checkpoint... Iteration: 630909224, states[0] = -95.076738, states[40]= 0.000000 Saving checkpoint... Iteration: 647447359, states[0] = -95.084538, states[40]= 0.000000 Saving checkpoint... Iteration: 664006985, states[0] = 27.417823, states[40]= 0.100692 Saving checkpoint... Iteration: 680488647, states[0] = -95.090349, states[40]= 0.000000 Saving checkpoint... Iteration: 697837959, states[0] = -95.051926, states[40]= 0.000000 Saving checkpoint... Iteration: 714498234, states[0] = -95.091385, states[40]= 0.000000 Saving checkpoint... Iteration: 731756844, states[0] = -94.991940, states[40]= 0.000000 Saving checkpoint... Iteration: 748942077, states[0] = -95.083555, states[40]= 0.000000 Saving checkpoint... Iteration: 765527285, states[0] = 20.903640, states[40]= 0.006892 Saving checkpoint... Iteration: 782193468, states[0] = -94.897228, states[40]= 0.000000 Saving checkpoint... Iteration: 798732866, states[0] = -94.962394, states[40]= 0.000000 Saving checkpoint... Iteration: 815548158, states[0] = 13.394233, states[40]= 0.005216 Saving checkpoint... Iteration: 832030436, states[0] = 19.911882, states[40]= 0.006338 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 832030436 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 19.911882 (After loading) - states[40]: 0.006338 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 849201757, states[0] = -94.912593, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 849201757 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.912593 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 865978396, states[0] = -95.088996, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 865978396 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.088996 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 882415085, states[0] = -95.077977, states[40]= 0.000000 Saving checkpoint... Iteration: 898139592, states[0] = -58.452091, states[40]= 0.000008 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 898139592 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -58.452091 (After loading) - states[40]: 0.000008 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 913414898, states[0] = -95.077915, states[40]= 0.000000 Saving checkpoint... Iteration: 928992222, states[0] = -95.090606, states[40]= 0.000000 Saving checkpoint... Iteration: 943842906, states[0] = -95.054097, states[40]= 0.000000 Saving checkpoint... Iteration: 957601774, states[0] = -19.485989, states[40]= 0.001027 Saving checkpoint... Iteration: 968444010, states[0] = -95.083767, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 968444010 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.083767 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 980584945, states[0] = -4.868791, states[40]= 0.003474 Saving checkpoint... Iteration: 997145546, states[0] = -66.159464, states[40]= 0.000002 Saving checkpoint... Iteration: 1013953999, states[0] = -95.085417, states[40]= 0.000000 Saving checkpoint... Iteration: 1025327915, states[0] = -95.046668, states[40]= 0.000000 Saving checkpoint... Iteration: 1042431362, states[0] = -95.081362, states[40]= 0.000000 Saving checkpoint... Iteration: 1059226079, states[0] = -94.952525, states[40]= 0.000000 Saving checkpoint... Iteration: 1074907925, states[0] = -95.076155, states[40]= 0.000000 Saving checkpoint... Iteration: 1091163110, states[0] = -92.793504, states[40]= 0.000000 Saving checkpoint... Iteration: 1107869345, states[0] = -95.064672, states[40]= 0.000000 Saving checkpoint... Iteration: 1124343460, states[0] = -95.054242, states[40]= 0.000000 Saving checkpoint... Iteration: 1141048149, states[0] = 13.397852, states[40]= 0.005217 Saving checkpoint... Iteration: 1157534278, states[0] = 18.613828, states[40]= 0.005894 Saving checkpoint... Iteration: 1173675976, states[0] = -94.832826, states[40]= 0.000000 Saving checkpoint... Iteration: 1189908199, states[0] = -95.076155, states[40]= 0.000000 Saving checkpoint... Iteration: 1206336506, states[0] = -95.050921, states[40]= 0.000000 Saving checkpoint... Iteration: 1222925591, states[0] = -95.080081, states[40]= 0.000000 Saving checkpoint... Iteration: 1239719735, states[0] = -94.942756, states[40]= 0.000000 Saving checkpoint... Iteration: 1256436020, states[0] = -95.082137, states[40]= 0.000000 Saving checkpoint... Iteration: 1273235897, states[0] = -94.966245, states[40]= 0.000000 Saving checkpoint... Iteration: 1289701964, states[0] = -94.912703, states[40]= 0.000000 Saving checkpoint... Iteration: 1306201208, states[0] = -94.911325, states[40]= 0.000000 Saving checkpoint... Iteration: 1322545926, states[0] = 14.272700, states[40]= 0.005271 Saving checkpoint... Iteration: 1339208391, states[0] = -94.924017, states[40]= 0.000000 Saving checkpoint... Iteration: 1355702489, states[0] = -94.913609, states[40]= 0.000000 Saving checkpoint... Iteration: 1365744367, states[0] = -94.977102, states[40]= 0.000000 Saving checkpoint... Iteration: 1377239233, states[0] = -94.970592, states[40]= 0.000000 Saving checkpoint... Iteration: 1393654524, states[0] = -80.798259, states[40]= 0.000000 Saving checkpoint... Iteration: 1410127600, states[0] = -44.604543, states[40]= 0.000070 Saving checkpoint... Iteration: 1426617241, states[0] = -34.091195, states[40]= 0.000308 Saving checkpoint... Iteration: 1443544610, states[0] = 14.785193, states[40]= 0.005309 Saving checkpoint... Iteration: 1460326235, states[0] = -95.045512, states[40]= 0.000000 Saving checkpoint... Iteration: 1471727222, states[0] = -94.953959, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1471727222 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.953959 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 1484178891, states[0] = -94.857328, states[40]= 0.000000 Saving checkpoint... Iteration: 1499762643, states[0] = -94.997597, states[40]= 0.000000 Saving checkpoint... Iteration: 1514969084, states[0] = -95.294589, states[40]= 0.000000 Saving checkpoint... Iteration: 1529661536, states[0] = -95.301420, states[40]= 0.000000 Saving checkpoint... Iteration: 1544705652, states[0] = 30.442900, states[40]= 0.115199 Saving checkpoint... Iteration: 1560060148, states[0] = 2.715006, states[40]= 0.005253 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1560060148 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 2.715006 (After loading) - states[40]: 0.005253 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1560060148 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 2.715006 (After loading) - states[40]: 0.005253 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1560060148 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 2.715006 (After loading) - states[40]: 0.005253 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 1576362847, states[0] = -95.166228, states[40]= 0.000000 Saving checkpoint... Iteration: 1592192986, states[0] = -28.154841, states[40]= 0.000573 Saving checkpoint... Iteration: 1606275874, states[0] = -10.033927, states[40]= 0.002671 Saving checkpoint... Iteration: 1622220722, states[0] = -61.645814, states[40]= 0.000005 Saving checkpoint... Iteration: 1638478565, states[0] = -95.209198, states[40]= 0.000000 Saving checkpoint... Iteration: 1653793632, states[0] = -95.239604, states[40]= 0.000000 Saving checkpoint... Iteration: 1665076570, states[0] = -10.835056, states[40]= 0.002489 Saving checkpoint... Iteration: 1680484200, states[0] = -95.221630, states[40]= 0.000000 Saving checkpoint... Iteration: 1696121324, states[0] = -95.283979, states[40]= 0.000000 Saving checkpoint... Iteration: 1706589730, states[0] = -95.232678, states[40]= 0.000000 Saving checkpoint... Iteration: 1721677016, states[0] = -95.340329, states[40]= 0.000000 Saving checkpoint... Iteration: 1737546501, states[0] = -95.313808, states[40]= 0.000000 Saving checkpoint... Iteration: 1753421369, states[0] = -95.284118, states[40]= 0.000000 Saving checkpoint... Iteration: 1768099641, states[0] = -95.250780, states[40]= 0.000000 Saving checkpoint... Iteration: 1783664183, states[0] = -95.176242, states[40]= 0.000000 Saving checkpoint... Iteration: 1796112238, states[0] = 24.869420, states[40]= 0.032855 Saving checkpoint... Iteration: 1809174636, states[0] = -94.883731, states[40]= 0.000000 Saving checkpoint... Iteration: 1822642162, states[0] = -65.181244, states[40]= 0.000002 Saving checkpoint... Iteration: 1837658459, states[0] = -90.300461, states[40]= 0.000000 Saving checkpoint... Iteration: 1852679467, states[0] = -94.877084, states[40]= 0.000000 Saving checkpoint... Iteration: 1868621357, states[0] = -38.785316, states[40]= 0.000164 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1868621357 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -38.785316 (After loading) - states[40]: 0.000164 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 1885971017, states[0] = -95.092803, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1885971017 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.092803 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 1902604061, states[0] = -21.849246, states[40]= 0.000884 Saving checkpoint... Iteration: 1918135888, states[0] = -54.201126, states[40]= 0.000015 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1918135888 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -54.201126 (After loading) - states[40]: 0.000015 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 1934458282, states[0] = -95.086856, states[40]= 0.000000 Saving checkpoint... Iteration: 1949124851, states[0] = -41.757988, states[40]= 0.000107 Saving checkpoint... Iteration: 1959667351, states[0] = -94.321639, states[40]= 0.000000 Saving checkpoint... Iteration: 1974538823, states[0] = 16.972008, states[40]= 0.005559 Saving checkpoint... Iteration: 1988953932, states[0] = -95.085062, states[40]= 0.000000 Saving checkpoint... Iteration: 2003386088, states[0] = -95.069767, states[40]= 0.000000 Saving checkpoint... Iteration: 2018326969, states[0] = -95.045643, states[40]= 0.000000 Saving checkpoint... Iteration: 2033508109, states[0] = 26.403906, states[40]= 0.078994 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 2033508109 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 26.403906 (After loading) - states[40]: 0.078994 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 2033508109 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 26.403906 (After loading) - states[40]: 0.078994 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 2033508109 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 26.403906 (After loading) - states[40]: 0.078994 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 2033508109 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 26.403906 (After loading) - states[40]: 0.078994 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pueyo_APDR-conf_851_0_r714249622_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 99.663222 * GNaL_b in INaL: 0.007890 * Gto_b in Ito: 0.070665 * PCa_b in ICaL: 0.000081 * GKr_b in IKr: 0.032959 * GKs_b in IKs: 0.001881 * GK1_b in IK1: 0.170876 * Gncx_b in INaCa_i: 0.000960 * Pnak_b in INaK: 63.243412 * GKb_b in IKb: 0.003973 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.047047 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 2033508109 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: 26.403906 (After loading) - states[40]: 0.078994 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 2050589143, states[0] = -8.100928, states[40]= 0.002773 Saving checkpoint... Iteration: 2067621039, states[0] = -37.812215, states[40]= 0.000188 Saving checkpoint... Iteration: 2084389932, states[0] = -95.070686, states[40]= 0.000000 Total time: 4200000.000000 State Variables: - v in component membrane (millivolt): -94.966577 - CaMKt in component CaMK (millimolar): 0.006968 - cass in component intracellular_ions (millimolar): 0.000074 - nai in component intracellular_ions (millimolar): 6.789004 - nass in component intracellular_ions (millimolar): 6.789064 - ki in component intracellular_ions (millimolar): 145.188740 - kss in component intracellular_ions (millimolar): 145.188719 - cansr in component intracellular_ions (millimolar): 1.313232 - cajsr in component intracellular_ions (millimolar): 1.275210 - cai in component intracellular_ions (millimolar): 0.000075 - m in component INa (dimensionless): 0.003595 - hf in component INa (dimensionless): 0.881119 - hs in component INa (dimensionless): 0.881115 - j in component INa (dimensionless): 0.881090 - hsp in component INa (dimensionless): 0.727944 - jp in component INa (dimensionless): 0.881072 - mL in component INaL (dimensionless): 0.000049 - hL in component INaL (dimensionless): 0.711742 - hLp in component INaL (dimensionless): 0.454300 - a in component Ito (dimensionless): 0.000621 - iF in component Ito (dimensionless): 0.999871 - iS in component Ito (dimensionless): 0.620717 - ap in component Ito (dimensionless): 0.000316 - iFp in component Ito (dimensionless): 0.999871 - iSp in component Ito (dimensionless): 0.695063 - d in component ICaL (dimensionless): 0.000000 - ff in component ICaL (dimensionless): 1.000000 - fs in component ICaL (dimensionless): 0.930877 - fcaf in component ICaL (dimensionless): 1.000000 - fcas in component ICaL (dimensionless): 0.999873 - jca in component ICaL (dimensionless): 0.999977 - ffp in component ICaL (dimensionless): 1.000000 - fcafp in component ICaL (dimensionless): 1.000000 - nca in component ICaL (dimensionless): 0.001616 - xrf in component IKr (dimensionless): 0.000003 - xrs in component IKr (dimensionless): 0.340020 - xs1 in component IKs (dimensionless): 0.246920 - xs2 in component IKs (dimensionless): 0.000087 - xk1 in component IK1 (dimensionless): 0.997320 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000 20:22:25 (26972): called boinc_finish(0) </stderr_txt> ]]>