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Task 54652957

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pieske_333-conf_45_0
Workunit 25948190
Created 25 Jun 2024, 9:05:40 UTC
Sent 25 Jun 2024, 13:47:11 UTC
Report deadline 28 Jun 2024, 13:47:11 UTC
Received 25 Jun 2024, 16:54:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234818
Run time 1 hours 4 min 55 sec
CPU time 45 min 31 sec
Validate state Valid
Credit 42.77
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.98 MB
Peak swap size 391.82 GB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pieske_333-conf_45.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pieske_333-conf_45_0_r1484445007_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Pieske_333-conf_45_0_r1484445007_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 120.164162
     * GNaL_b in INaL: 0.009019
     * Gto_b in Ito: 0.075065
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033683
     * GKs_b in IKs: 0.001815
     * GK1_b in IK1: 0.164558
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 69.046463
     * GKb_b in IKb: 0.003855
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035810
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 39228093, states[0] = -23.600342, states[40]= 0.000915
Saving checkpoint... 
Iteration: 63144949, states[0] = -87.763654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85477022, states[0] = -87.770704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115584363, states[0] = -69.741395, states[40]= 0.000002
Saving checkpoint... 
Iteration: 145348814, states[0] = 13.127029, states[40]= 0.008700
Saving checkpoint... 
Iteration: 186953878, states[0] = -87.732058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227670818, states[0] = 15.060360, states[40]= 0.009352
Saving checkpoint... 
Iteration: 262580266, states[0] = -85.215090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280091537, states[0] = -87.612770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301062049, states[0] = -63.351599, states[40]= 0.000005
Saving checkpoint... 
Iteration: 330381629, states[0] = -46.728519, states[40]= 0.000062
Saving checkpoint... 
Iteration: 366181387, states[0] = -4.857557, states[40]= 0.004864
Saving checkpoint... 
Iteration: 402602487, states[0] = -87.743952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439894016, states[0] = -83.669666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471687825, states[0] = -28.373617, states[40]= 0.000604
Saving checkpoint... 
Iteration: 492531648, states[0] = -46.103761, states[40]= 0.000068
Saving checkpoint... 
Iteration: 519354867, states[0] = -35.567987, states[40]= 0.000279
Saving checkpoint... 
Iteration: 554458743, states[0] = 21.825488, states[40]= 0.023419
Saving checkpoint... 
Iteration: 587684540, states[0] = -40.017506, states[40]= 0.000158
Saving checkpoint... 
Iteration: 630289122, states[0] = 19.561197, states[40]= 0.013816
Saving checkpoint... 
Iteration: 675636464, states[0] = 8.031283, states[40]= 0.007646
Saving checkpoint... 
Iteration: 711778080, states[0] = 20.990154, states[40]= 0.018526
Saving checkpoint... 
Iteration: 734874442, states[0] = -87.431379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753623396, states[0] = 11.756511, states[40]= 0.008360
Saving checkpoint... 
Iteration: 780560958, states[0] = -87.730704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808938118, states[0] = 19.462125, states[40]= 0.013598
Saving checkpoint... 
Iteration: 849819402, states[0] = -32.196287, states[40]= 0.000411
Saving checkpoint... 
Iteration: 893979880, states[0] = -29.715102, states[40]= 0.000531
Saving checkpoint... 
Iteration: 939342839, states[0] = -82.289729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977284936, states[0] = -2.586904, states[40]= 0.005509
Saving checkpoint... 
Iteration: 998792901, states[0] = -15.721648, states[40]= 0.001921
Saving checkpoint... 
Iteration: 1016290408, states[0] = -14.660146, states[40]= 0.002134
Saving checkpoint... 
Iteration: 1040285475, states[0] = -11.098211, states[40]= 0.003003
Saving checkpoint... 
Iteration: 1072100729, states[0] = 4.967136, states[40]= 0.007128
Saving checkpoint... 
Iteration: 1106506469, states[0] = -87.553221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144045109, states[0] = -87.793552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186654360, states[0] = -85.107741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225921381, states[0] = 2.658164, states[40]= 0.006711
Saving checkpoint... 
Iteration: 1248247682, states[0] = 6.642431, states[40]= 0.007412
Saving checkpoint... 
Iteration: 1271502040, states[0] = -87.691663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297898801, states[0] = 14.023012, states[40]= 0.008969
Saving checkpoint... 
Iteration: 1331396802, states[0] = 13.163521, states[40]= 0.008711
Saving checkpoint... 
Iteration: 1358507434, states[0] = -87.744848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385853353, states[0] = -87.790789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404092579, states[0] = -25.555079, states[40]= 0.000778
Saving checkpoint... 
Iteration: 1413768637, states[0] = -40.079732, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1424654801, states[0] = -87.697686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437493593, states[0] = -87.724043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453462239, states[0] = -85.848509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474146072, states[0] = -87.679653, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.686877
 - CaMKt in component CaMK (millimolar): 0.038883
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 7.087725
 - nass in component intracellular_ions (millimolar): 7.087871
 - ki in component intracellular_ions (millimolar): 144.841362
 - kss in component intracellular_ions (millimolar): 144.841329
 - cansr in component intracellular_ions (millimolar): 1.584719
 - cajsr in component intracellular_ions (millimolar): 1.171424
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007486
 - hf in component INa (dimensionless): 0.691461
 - hs in component INa (dimensionless): 0.691241
 - j in component INa (dimensionless): 0.681836
 - hsp in component INa (dimensionless): 0.446286
 - jp in component INa (dimensionless): 0.657065
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.298358
 - hLp in component INaL (dimensionless): 0.139388
 - a in component Ito (dimensionless): 0.001014
 - iF in component Ito (dimensionless): 0.999538
 - iS in component Ito (dimensionless): 0.178285
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999538
 - iSp in component Ito (dimensionless): 0.215662
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.802652
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.965691
 - jca in component ICaL (dimensionless): 0.949225
 - ffp in component ICaL (dimensionless): 0.999881
 - fcafp in component ICaL (dimensionless): 0.999992
 - nca in component ICaL (dimensionless): 0.009213
 - xrf in component IKr (dimensionless): 0.028386
 - xrs in component IKr (dimensionless): 0.803693
 - xs1 in component IKs (dimensionless): 0.456484
 - xs2 in component IKs (dimensionless): 0.001099
 - xk1 in component IK1 (dimensionless): 0.996814
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:53:26 (34319): called boinc_finish(0)

</stderr_txt>
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