𝕏

Task 54639207

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Drouin_ENDO_4000-conf_726_0
Workunit 25941321
Created 25 Jun 2024, 8:58:29 UTC
Sent 25 Jun 2024, 12:17:44 UTC
Report deadline 28 Jun 2024, 12:17:44 UTC
Received 25 Jun 2024, 16:23:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 206632
Run time 1 hours 46 min 34 sec
CPU time 1 hours 46 min 34 sec
Validate state Valid
Credit 43.57
Device peak FLOPS 3.04 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.48 MB
Peak swap size 1.36 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Drouin_ENDO_4000-conf_726.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Drouin_ENDO_4000-conf_726_0_r401900831_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Drouin_ENDO_4000-conf_726_0_r401900831_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.196007
     * GNaL_b in INaL: 0.009004
     * Gto_b in Ito: 0.066125
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033782
     * GKs_b in IKs: 0.001766
     * GK1_b in IK1: 0.158468
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.567484
     * GKb_b in IKb: 0.003861
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049982
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11331491, states[0] = -94.148088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20328673, states[0] = -93.900913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27332906, states[0] = -94.060107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33954192, states[0] = -94.031942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40948867, states[0] = -94.051472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47662842, states[0] = -94.023456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59262209, states[0] = -94.030843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71622131, states[0] = -94.018552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84688745, states[0] = -94.044073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96299333, states[0] = -93.739059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110702112, states[0] = -94.044162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124586898, states[0] = -94.033187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136835694, states[0] = -94.043899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146875217, states[0] = -94.042753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159333939, states[0] = -94.025319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162860075, states[0] = -94.043154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168648166, states[0] = -94.040806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181425865, states[0] = -94.022351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193025340, states[0] = -94.036944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205114593, states[0] = -94.033284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217291638, states[0] = -94.026600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220656044, states[0] = -94.041303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231252457, states[0] = -94.027954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245561183, states[0] = -94.018434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257410444, states[0] = -94.022640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269953638, states[0] = -94.010196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283924235, states[0] = -94.010666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295189061, states[0] = -94.030170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302463068, states[0] = -93.988264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307028182, states[0] = -94.036578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318202896, states[0] = -75.614033, states[40]= 0.000004
Saving checkpoint... 
Iteration: 325330422, states[0] = -94.025051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331931147, states[0] = -94.010448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339084535, states[0] = -94.034211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344679970, states[0] = -94.042554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352656794, states[0] = -94.041081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364610150, states[0] = -94.036222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376810553, states[0] = -94.043856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383832344, states[0] = -94.012127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390742997, states[0] = -94.044236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397526183, states[0] = -94.019038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408685115, states[0] = -94.042679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417524080, states[0] = -94.019053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423624811, states[0] = -94.016484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431019274, states[0] = -94.036687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443685399, states[0] = -94.015040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458642484, states[0] = -94.039680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462348048, states[0] = -93.857160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465890390, states[0] = -94.010887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477347576, states[0] = -94.024174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490127178, states[0] = -12.768800, states[40]= 0.002417
Saving checkpoint... 
Iteration: 503775106, states[0] = -94.013006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513515111, states[0] = -94.019099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527557164, states[0] = -94.017956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539449916, states[0] = -94.020881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553749628, states[0] = -94.013427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567139218, states[0] = -94.031550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573638204, states[0] = -94.015859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586295924, states[0] = -93.726901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597946443, states[0] = -94.009643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599126379, states[0] = -94.031995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602983291, states[0] = -94.037792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610370830, states[0] = -93.895530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616868109, states[0] = -94.041949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627381414, states[0] = -94.022780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632867743, states[0] = -94.041927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644949799, states[0] = -94.039025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660098185, states[0] = 6.203300, states[40]= 0.004472
Saving checkpoint... 
Iteration: 674473727, states[0] = -93.993780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689012712, states[0] = -94.036428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697238875, states[0] = -94.027487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701919768, states[0] = -94.009886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706486242, states[0] = -94.000309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711379302, states[0] = -94.022675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716913063, states[0] = -94.040249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725318866, states[0] = -94.024620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728473706, states[0] = -93.993658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731469432, states[0] = -94.019925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737950222, states[0] = -94.009293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745171403, states[0] = -94.029928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753720025, states[0] = -94.013646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759940451, states[0] = -94.009413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773212449, states[0] = -94.028309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787232394, states[0] = -94.027541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802038744, states[0] = 29.192477, states[40]= 0.000411
Saving checkpoint... 
Iteration: 817020970, states[0] = -94.035830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825749949, states[0] = -94.012864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836059133, states[0] = 22.461977, states[40]= 0.001163
Saving checkpoint... 
Iteration: 849052697, states[0] = -94.034468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857665007, states[0] = -94.014655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868382103, states[0] = -93.911143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881156640, states[0] = -94.030224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888509855, states[0] = -94.010398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895535356, states[0] = -94.017775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902516120, states[0] = -94.012763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909252728, states[0] = -94.026551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915021313, states[0] = -94.035616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923677789, states[0] = -94.014229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933656195, states[0] = -94.014702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935428143, states[0] = -94.020715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948117899, states[0] = -5.626200, states[40]= 0.003976
Saving checkpoint... 
Iteration: 957685074, states[0] = -94.013996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972356678, states[0] = -93.871800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984858080, states[0] = -94.041493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990211420, states[0] = -86.681389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001432182, states[0] = -94.020460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005626113, states[0] = -94.015263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017352676, states[0] = -94.022904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025868850, states[0] = -94.010131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033753004, states[0] = -94.012375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044676439, states[0] = -94.040938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054319875, states[0] = -93.794142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062956417, states[0] = -94.037916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066185779, states[0] = -58.403626, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1076025283, states[0] = 32.537191, states[40]= 0.000496
Saving checkpoint... 
Iteration: 1082441981, states[0] = -93.972185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092769948, states[0] = -94.042857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103338963, states[0] = -94.023177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112066714, states[0] = 19.706792, states[40]= 0.001661
Saving checkpoint... 
Iteration: 1122044756, states[0] = 27.335191, states[40]= 0.000558
Saving checkpoint... 
Iteration: 1128623642, states[0] = -94.036367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139550134, states[0] = -94.016887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150102691, states[0] = 3.849008, states[40]= 0.004719
Saving checkpoint... 
Iteration: 1159518905, states[0] = -94.017675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161687484, states[0] = -94.013525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166569064, states[0] = -94.027434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176643052, states[0] = -94.038268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190124721, states[0] = -10.816060, states[40]= 0.002786
Saving checkpoint... 
Iteration: 1200546966, states[0] = -94.021992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211865422, states[0] = -94.009813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223615185, states[0] = -94.015080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229593948, states[0] = -94.015588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240424115, states[0] = -93.957074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250046815, states[0] = 26.669188, states[40]= 0.000621
Saving checkpoint... 
Iteration: 1256734813, states[0] = -94.042383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268964921, states[0] = -94.037162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278760568, states[0] = -94.042497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288874373, states[0] = -94.040385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298580170, states[0] = -94.029427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309536361, states[0] = -94.016901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315820073, states[0] = -94.010455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326655558, states[0] = -94.039001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336579075, states[0] = -94.029138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348149163, states[0] = -29.253621, states[40]= 0.002929
Saving checkpoint... 
Iteration: 1351752127, states[0] = -94.011743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358981656, states[0] = -94.036314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365442482, states[0] = -94.019410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380417232, states[0] = -93.950377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394924989, states[0] = -94.038432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397846740, states[0] = -94.009780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398633660, states[0] = -94.036910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401520499, states[0] = -94.017137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416082152, states[0] = 13.597460, states[40]= 0.003033
Saving checkpoint... 
Iteration: 1429772007, states[0] = -94.011174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435492100, states[0] = -94.017846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438621672, states[0] = -94.035503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448748867, states[0] = -94.042119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458817966, states[0] = -94.041509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472985506, states[0] = -94.035928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488332359, states[0] = -93.822801, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.882887
 - CaMKt in component CaMK (millimolar): 0.002074
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.749019
 - nass in component intracellular_ions (millimolar): 6.749141
 - ki in component intracellular_ions (millimolar): 145.112217
 - kss in component intracellular_ions (millimolar): 145.112206
 - cansr in component intracellular_ions (millimolar): 1.832360
 - cajsr in component intracellular_ions (millimolar): 1.832111
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004010
 - hf in component INa (dimensionless): 0.861164
 - hs in component INa (dimensionless): 0.861165
 - j in component INa (dimensionless): 0.861169
 - hsp in component INa (dimensionless): 0.691317
 - jp in component INa (dimensionless): 0.861171
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.701516
 - hLp in component INaL (dimensionless): 0.506107
 - a in component Ito (dimensionless): 0.000668
 - iF in component Ito (dimensionless): 0.999844
 - iS in component Ito (dimensionless): 0.991409
 - ap in component Ito (dimensionless): 0.000340
 - iFp in component Ito (dimensionless): 0.999844
 - iSp in component Ito (dimensionless): 0.996560
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996307
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005295
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008109
 - xs1 in component IKs (dimensionless): 0.042220
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997592
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:56:59 (12256): called boinc_finish(0)

</stderr_txt>
]]>


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