𝕏

Task 54625934

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_810_0
Workunit 25934693
Created 25 Jun 2024, 8:51:36 UTC
Sent 25 Jun 2024, 10:46:01 UTC
Report deadline 28 Jun 2024, 10:46:11 UTC
Received 26 Jun 2024, 7:30:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220836
Run time 38 min 8 sec
CPU time 32 min 47 sec
Validate state Valid
Credit 40.02
Device peak FLOPS 5.24 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.61 MB
Peak swap size 391.88 GB
Peak disk usage 0.22 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_810.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_810_0_r1968875870_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_810_0_r1968875870_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.020903
     * GNaL_b in INaL: 0.006856
     * Gto_b in Ito: 0.093584
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034085
     * GKs_b in IKs: 0.001863
     * GK1_b in IK1: 0.165725
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 68.373101
     * GKb_b in IKb: 0.003932
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038492
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 3939555, states[0] = -84.703498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 7023210, states[0] = -54.344060, states[40]= 0.000030
Saving checkpoint... 
Iteration: 11900450, states[0] = -40.498875, states[40]= 0.000127
Saving checkpoint... 
Iteration: 16911691, states[0] = -84.684137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 20542118, states[0] = -60.917803, states[40]= 0.000007
Saving checkpoint... 
Iteration: 24180883, states[0] = 26.909782, states[40]= 0.000040
Saving checkpoint... 
Iteration: 28022182, states[0] = -68.028074, states[40]= 0.000002
Saving checkpoint... 
Iteration: 33129734, states[0] = 7.288737, states[40]= 0.000093
Saving checkpoint... 
Iteration: 37564993, states[0] = -84.415330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41061863, states[0] = -84.699650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45082814, states[0] = -84.685243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49841693, states[0] = -31.541760, states[40]= 0.000118
Saving checkpoint... 
Iteration: 54645505, states[0] = 30.364058, states[40]= 0.001480
Saving checkpoint... 
Iteration: 59302795, states[0] = -1.024523, states[40]= 0.000176
Saving checkpoint... 
Iteration: 63013691, states[0] = 16.689611, states[40]= 0.000015
Saving checkpoint... 
Iteration: 67149947, states[0] = -84.148904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70975835, states[0] = -84.772378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74653086, states[0] = -84.441946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78764987, states[0] = -84.853955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 83021523, states[0] = -84.647949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87496148, states[0] = -22.462697, states[40]= 0.000120
Saving checkpoint... 
Iteration: 91324212, states[0] = -84.413970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95407913, states[0] = -84.758135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99417157, states[0] = -84.691524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103958090, states[0] = -84.264304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108177348, states[0] = -0.917574, states[40]= 0.000163
Saving checkpoint... 
Iteration: 113270429, states[0] = -84.871890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117328580, states[0] = 27.610406, states[40]= 0.000084
Saving checkpoint... 
Iteration: 121702965, states[0] = -15.508921, states[40]= 0.000142
Saving checkpoint... 
Iteration: 125535301, states[0] = -84.404889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130488727, states[0] = -84.781880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133582981, states[0] = -84.384907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137167375, states[0] = 27.075335, states[40]= 0.000054
Saving checkpoint... 
Iteration: 141730281, states[0] = -84.866541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145917500, states[0] = -83.928372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149511181, states[0] = 30.414194, states[40]= 0.042287
Saving checkpoint... 
Iteration: 154394699, states[0] = 29.040113, states[40]= 0.176804
Saving checkpoint... 
Iteration: 159533337, states[0] = -84.805827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164509689, states[0] = 11.619903, states[40]= 0.000036
Saving checkpoint... 
Iteration: 169146125, states[0] = -22.655088, states[40]= 0.000117
Saving checkpoint... 
Iteration: 173905628, states[0] = -84.796803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177893065, states[0] = -84.633669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182054923, states[0] = 6.638693, states[40]= 0.000077
Saving checkpoint... 
Iteration: 185603191, states[0] = -84.208211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189817168, states[0] = 6.811890, states[40]= 0.000075
Saving checkpoint... 
Iteration: 194094517, states[0] = 26.155809, states[40]= 0.000026
Saving checkpoint... 
Iteration: 198859366, states[0] = -84.496566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203272074, states[0] = 29.903162, states[40]= 0.075481
Saving checkpoint... 
Iteration: 206180919, states[0] = 20.703517, states[40]= 0.000006
Saving checkpoint... 
Iteration: 211170582, states[0] = -81.964234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215827255, states[0] = -84.534625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219900327, states[0] = -84.777491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225110566, states[0] = -84.877184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230079168, states[0] = -2.646423, states[40]= 0.000175
Saving checkpoint... 
Iteration: 233878247, states[0] = -78.196284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237047734, states[0] = -82.827845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241961153, states[0] = -84.295469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245651465, states[0] = -59.193655, states[40]= 0.000007
Saving checkpoint... 
Iteration: 250783931, states[0] = -7.606502, states[40]= 0.000187
Saving checkpoint... 
Iteration: 255044912, states[0] = 25.982178, states[40]= 0.000023
Saving checkpoint... 
Iteration: 259021693, states[0] = -84.842478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262668034, states[0] = -84.360434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267508481, states[0] = -68.624466, states[40]= 0.000002
Saving checkpoint... 
Iteration: 272324281, states[0] = 10.323082, states[40]= 0.000045
Saving checkpoint... 
Iteration: 277106774, states[0] = -84.753364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281257394, states[0] = -5.906341, states[40]= 0.000189
Saving checkpoint... 
Iteration: 284534703, states[0] = -84.496630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288795273, states[0] = -81.801809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291629406, states[0] = -32.658008, states[40]= 0.000101
Saving checkpoint... 
Iteration: 295689916, states[0] = -77.265558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299699443, states[0] = -56.636082, states[40]= 0.000010
Saving checkpoint... 
Iteration: 301835720, states[0] = -84.767525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 307095569, states[0] = 19.589738, states[40]= 0.000008
Saving checkpoint... 
Iteration: 311500825, states[0] = -75.307322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 316601524, states[0] = 8.895826, states[40]= 0.000056
Saving checkpoint... 
Iteration: 321732386, states[0] = 30.393610, states[40]= 0.001847
Saving checkpoint... 
Iteration: 326611007, states[0] = 30.364914, states[40]= 0.045028
Saving checkpoint... 
Iteration: 331148842, states[0] = -84.719300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 335592673, states[0] = -3.616091, states[40]= 0.000181
Saving checkpoint... 
Iteration: 339857155, states[0] = 26.095930, states[40]= 0.000025
Saving checkpoint... 
Iteration: 344705636, states[0] = -84.862462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348709853, states[0] = -84.805624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354016003, states[0] = -31.581930, states[40]= 0.000105
Saving checkpoint... 
Iteration: 358109999, states[0] = -84.280283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361696750, states[0] = 29.941977, states[40]= 0.000949
Saving checkpoint... 
Iteration: 366582751, states[0] = 30.314173, states[40]= 0.001620
Saving checkpoint... 
Iteration: 371775796, states[0] = 23.257040, states[40]= 0.000006
Saving checkpoint... 
Iteration: 376133343, states[0] = -6.941993, states[40]= 0.000188
Saving checkpoint... 
Iteration: 379595714, states[0] = -22.153834, states[40]= 0.000117
Saving checkpoint... 
Iteration: 384055170, states[0] = -84.743939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387796966, states[0] = -84.760358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392616254, states[0] = -84.340155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396848633, states[0] = -25.728578, states[40]= 0.000117
Saving checkpoint... 
Iteration: 401037373, states[0] = -84.811847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404776301, states[0] = -84.816016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409608474, states[0] = -84.570066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413952592, states[0] = -84.732660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417635901, states[0] = -84.403006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422784154, states[0] = -84.084658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426875656, states[0] = -84.666686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431309457, states[0] = 11.759740, states[40]= 0.000035
Saving checkpoint... 
Iteration: 435323372, states[0] = 18.101526, states[40]= 0.000010
Saving checkpoint... 
Iteration: 438288514, states[0] = -75.538683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441983957, states[0] = -23.067530, states[40]= 0.000117
Saving checkpoint... 
Iteration: 447373830, states[0] = 29.326262, states[40]= 0.000452
Saving checkpoint... 
Iteration: 452450158, states[0] = -84.594590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 456465742, states[0] = -84.534285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460391949, states[0] = -32.702368, states[40]= 0.000101
Saving checkpoint... 
Iteration: 464613707, states[0] = 30.866853, states[40]= 0.016997
Saving checkpoint... 
Iteration: 469761100, states[0] = -84.841350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474265916, states[0] = -84.334538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478328687, states[0] = -84.614467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482525526, states[0] = -28.013621, states[40]= 0.000115
Saving checkpoint... 
Iteration: 487393035, states[0] = -3.971240, states[40]= 0.000183
Saving checkpoint... 
Iteration: 491074941, states[0] = 28.957709, states[40]= 0.000305
Saving checkpoint... 
Iteration: 495461803, states[0] = -26.536933, states[40]= 0.000116
Saving checkpoint... 
Iteration: 499428922, states[0] = 21.718480, states[40]= 0.000005
Saving checkpoint... 
Iteration: 503341655, states[0] = -84.616388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506870165, states[0] = 29.191158, states[40]= 0.149709
Saving checkpoint... 
Iteration: 512038856, states[0] = 36.129517, states[40]= 0.964294
Saving checkpoint... 
Iteration: 516914530, states[0] = -84.848686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520508578, states[0] = -68.740197, states[40]= 0.000002
Saving checkpoint... 
Iteration: 524844486, states[0] = -84.012358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529701277, states[0] = -58.937278, states[40]= 0.000007
Saving checkpoint... 
Iteration: 534562690, states[0] = -27.606764, states[40]= 0.000115
Saving checkpoint... 
Iteration: 538441679, states[0] = -84.735437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542711763, states[0] = -84.503898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547250986, states[0] = -75.492617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551975863, states[0] = -84.810397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557161316, states[0] = -84.839352, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560555934, states[0] = -84.624662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564263053, states[0] = -84.416673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568203101, states[0] = -31.094245, states[40]= 0.000107
Saving checkpoint... 
Iteration: 572512528, states[0] = -27.409866, states[40]= 0.000116
Saving checkpoint... 
Iteration: 576892955, states[0] = -84.224293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580788787, states[0] = 23.021319, states[40]= 0.000005
Saving checkpoint... 
Iteration: 584438034, states[0] = -84.719061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588762670, states[0] = -84.766156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 593732656, states[0] = 19.808947, states[40]= 0.000007
Saving checkpoint... 
Iteration: 598479137, states[0] = -84.444690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602354382, states[0] = 21.488365, states[40]= 0.000005
Saving checkpoint... 
Iteration: 607559972, states[0] = 3.011894, states[40]= 0.000117
Saving checkpoint... 
Iteration: 611603008, states[0] = -15.615846, states[40]= 0.000140
Saving checkpoint... 
Iteration: 616083516, states[0] = -84.793553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620027643, states[0] = -84.322872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625024286, states[0] = -84.868242, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629934181, states[0] = 29.963526, states[40]= 0.000972
Saving checkpoint... 
Iteration: 634402074, states[0] = -84.317041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637651415, states[0] = -84.809527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641697201, states[0] = -84.863145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645751005, states[0] = 28.584103, states[40]= 0.000209
Saving checkpoint... 
Iteration: 650194742, states[0] = -84.017906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655399183, states[0] = -84.402481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660232655, states[0] = -67.436820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 663802210, states[0] = -84.771143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668388521, states[0] = -84.718636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672358383, states[0] = -84.373570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676505711, states[0] = 30.702223, states[40]= 0.003364
Saving checkpoint... 
Iteration: 680109556, states[0] = -84.265959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684870427, states[0] = 19.668426, states[40]= 0.000008
Saving checkpoint... 
Iteration: 688240513, states[0] = -84.773202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692174625, states[0] = -84.139561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696947476, states[0] = 18.585394, states[40]= 0.000009
Saving checkpoint... 
Iteration: 701123075, states[0] = -84.490568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705507454, states[0] = -84.824729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709684616, states[0] = -70.184759, states[40]= 0.000002
Saving checkpoint... 
Iteration: 714012781, states[0] = -83.413062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717300124, states[0] = -84.838029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720803916, states[0] = 21.724023, states[40]= 0.000005
Saving checkpoint... 
Iteration: 725558753, states[0] = -84.476393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730576259, states[0] = 23.036646, states[40]= 0.000005
Saving checkpoint... 
Iteration: 735208145, states[0] = 4.373561, states[40]= 0.000101
Saving checkpoint... 
Iteration: 739177710, states[0] = 30.938322, states[40]= 0.009888
Saving checkpoint... 
Iteration: 743269293, states[0] = -5.253238, states[40]= 0.000188
Saving checkpoint... 
Iteration: 748068719, states[0] = -84.852045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752285612, states[0] = -84.390476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756645774, states[0] = -84.693187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760617925, states[0] = -84.344443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764633644, states[0] = -84.253855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769285762, states[0] = -84.644345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773197605, states[0] = -39.369276, states[40]= 0.000064
Saving checkpoint... 
Iteration: 777461878, states[0] = 10.269253, states[40]= 0.000045
Saving checkpoint... 
Iteration: 781616199, states[0] = -84.435717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785178175, states[0] = 30.932721, states[40]= 0.008364
Saving checkpoint... 
Iteration: 789083906, states[0] = -84.374635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794166064, states[0] = -16.311161, states[40]= 0.000136
Saving checkpoint... 
Iteration: 799252096, states[0] = 35.091799, states[40]= 1.027445
Saving checkpoint... 
Iteration: 802011463, states[0] = -84.281651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806056571, states[0] = -84.457456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810653347, states[0] = -84.432034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814459235, states[0] = -84.790014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 817947572, states[0] = 30.080630, states[40]= 0.063058
Saving checkpoint... 
Iteration: 821983397, states[0] = 30.167131, states[40]= 0.001286
Saving checkpoint... 
Iteration: 824772670, states[0] = -84.639619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 829893599, states[0] = -84.224008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834184375, states[0] = -82.497344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839204972, states[0] = -84.846427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842609664, states[0] = -84.696864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847283858, states[0] = 30.051099, states[40]= 0.001091
Saving checkpoint... 
Iteration: 851863720, states[0] = 35.895747, states[40]= 0.840302
Saving checkpoint... 
Iteration: 856478931, states[0] = 30.898292, states[40]= 0.006373
Saving checkpoint... 
Iteration: 860935900, states[0] = -84.111130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865945846, states[0] = -84.853526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 868822638, states[0] = -84.857486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873579679, states[0] = -83.886206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877667302, states[0] = -84.608931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 882669347, states[0] = 20.232586, states[40]= 0.000007
Saving checkpoint... 
Iteration: 886082298, states[0] = 29.070988, states[40]= 0.170608
Saving checkpoint... 
Iteration: 890389164, states[0] = 36.001542, states[40]= 1.090497
Saving checkpoint... 
Iteration: 894410442, states[0] = -84.857415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899076352, states[0] = 9.015517, states[40]= 0.000055
Saving checkpoint... 
Iteration: 903479064, states[0] = -83.843634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907334750, states[0] = -84.824997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 911994782, states[0] = 20.007365, states[40]= 0.000007
Saving checkpoint... 
Iteration: 916687365, states[0] = -73.981817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 921123473, states[0] = -84.792313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924653939, states[0] = 15.018141, states[40]= 0.000020
Saving checkpoint... 
Iteration: 929866069, states[0] = -16.311990, states[40]= 0.000136
Saving checkpoint... 
Iteration: 934518419, states[0] = -80.575239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938929762, states[0] = -84.725971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 942380009, states[0] = -84.726853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946919192, states[0] = -84.350286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950687341, states[0] = -84.577870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954911969, states[0] = -56.630755, states[40]= 0.000010
Saving checkpoint... 
Iteration: 959167020, states[0] = 6.922180, states[40]= 0.000074
Saving checkpoint... 
Iteration: 963720295, states[0] = 30.310773, states[40]= 0.001594
Saving checkpoint... 
Iteration: 968364477, states[0] = 8.611564, states[40]= 0.000058
Saving checkpoint... 
Iteration: 970926274, states[0] = 23.032095, states[40]= 0.000005
Saving checkpoint... 
Iteration: 975012987, states[0] = -27.946669, states[40]= 0.000115
Saving checkpoint... 
Iteration: 979225506, states[0] = 13.137359, states[40]= 0.010066
Saving checkpoint... 
Iteration: 982314842, states[0] = -84.591742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986656537, states[0] = -84.731560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990349439, states[0] = -84.491779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993510159, states[0] = -84.478780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997074754, states[0] = 29.027273, states[40]= 0.000325
Saving checkpoint... 
Iteration: 1001579172, states[0] = -84.601691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006064190, states[0] = -29.390136, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1010661161, states[0] = -25.737700, states[40]= 0.000116
Saving checkpoint... 
Iteration: 1014890400, states[0] = 30.940068, states[40]= 0.009233
Saving checkpoint... 
Iteration: 1019244855, states[0] = 13.030095, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1022303015, states[0] = -84.716461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025427668, states[0] = -84.513380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029623363, states[0] = -9.835552, states[40]= 0.000178
Saving checkpoint... 
Iteration: 1034448914, states[0] = 29.305867, states[40]= 0.000439
Saving checkpoint... 
Iteration: 1038775003, states[0] = 23.646073, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1043617008, states[0] = -84.839337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047596976, states[0] = -84.689978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1051235708, states[0] = -71.687900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055680550, states[0] = -84.809200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059371780, states[0] = -84.627986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063998126, states[0] = -84.744763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067798781, states[0] = 29.348947, states[40]= 0.000460
Saving checkpoint... 
Iteration: 1070564130, states[0] = -84.504856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074626410, states[0] = -84.708286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079430578, states[0] = -83.930610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082540391, states[0] = -30.822791, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1085612760, states[0] = 30.754053, states[40]= 0.023906
Saving checkpoint... 
Iteration: 1090132172, states[0] = -84.615751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094315605, states[0] = -15.718954, states[40]= 0.000139
Saving checkpoint... 
Iteration: 1098884798, states[0] = 11.560932, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1103511901, states[0] = -11.089545, states[40]= 0.000171
Saving checkpoint... 
Iteration: 1107508981, states[0] = 12.057470, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1111309380, states[0] = -53.423766, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1115648329, states[0] = -82.959779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119985699, states[0] = -84.264335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124715382, states[0] = 30.941340, states[40]= 0.009292
Saving checkpoint... 
Iteration: 1128632904, states[0] = -84.457949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132749302, states[0] = -84.853446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134905359, states[0] = -80.120933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138483049, states[0] = -84.813668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142250768, states[0] = 30.825735, states[40]= 0.019903
Saving checkpoint... 
Iteration: 1147307609, states[0] = -84.352431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151952897, states[0] = -84.656297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156822283, states[0] = -84.556053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161339840, states[0] = -60.261393, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1165024529, states[0] = 1.414923, states[40]= 0.000135
Saving checkpoint... 
Iteration: 1168093165, states[0] = -84.806228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1172439771, states[0] = 30.936772, states[40]= 0.011578
Saving checkpoint... 
Iteration: 1175105621, states[0] = -18.889370, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1177264130, states[0] = -84.706177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181137103, states[0] = -11.334082, states[40]= 0.000169
Saving checkpoint... 
Iteration: 1185239322, states[0] = -84.159096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189315884, states[0] = -84.591616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193999781, states[0] = 30.671581, states[40]= 0.028414
Saving checkpoint... 
Iteration: 1198787415, states[0] = -84.488949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202886448, states[0] = -84.820795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206927040, states[0] = 35.223742, states[40]= 1.042091
Saving checkpoint... 
Iteration: 1211531875, states[0] = 28.953655, states[40]= 0.198283
Saving checkpoint... 
Iteration: 1215682992, states[0] = -67.861627, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1220354169, states[0] = -84.517766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223696178, states[0] = -22.692265, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1226487814, states[0] = 30.763724, states[40]= 0.023443
Saving checkpoint... 
Iteration: 1229069880, states[0] = 29.098540, states[40]= 0.165647
Saving checkpoint... 
Iteration: 1231620424, states[0] = -84.773587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1235442765, states[0] = 14.258695, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1239113251, states[0] = -84.824351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243970668, states[0] = -84.730263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245858568, states[0] = -52.425844, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1249806342, states[0] = 20.497402, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1254510527, states[0] = -82.865826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259460829, states[0] = -84.559479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263822044, states[0] = -84.777801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268355168, states[0] = -84.432720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273087224, states[0] = 23.782001, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1277874382, states[0] = -84.635043, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282226880, states[0] = -84.792002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287016740, states[0] = -84.188060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291740932, states[0] = 31.410765, states[40]= 0.662034
Saving checkpoint... 
Iteration: 1295989986, states[0] = -84.650030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300044975, states[0] = -84.770128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303934070, states[0] = -53.034658, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1307808826, states[0] = -84.774237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311637703, states[0] = 9.756434, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1314076783, states[0] = -84.498647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317389159, states[0] = 8.823285, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1321399583, states[0] = 17.455179, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1324978113, states[0] = -84.306012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328555954, states[0] = 30.671727, states[40]= 0.003082
Saving checkpoint... 
Iteration: 1332330622, states[0] = 14.052512, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1336638367, states[0] = 16.750007, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1340873747, states[0] = -84.780842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344590834, states[0] = -84.708262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1347826254, states[0] = 28.501429, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1350800977, states[0] = -58.505190, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1354684071, states[0] = -84.810090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359389040, states[0] = -13.735444, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1363827423, states[0] = -84.580877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368412375, states[0] = -84.483593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373134875, states[0] = 24.884385, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1378030426, states[0] = 20.968047, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1382664856, states[0] = -0.960701, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1385505179, states[0] = 21.093871, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1389451832, states[0] = -84.748494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394176501, states[0] = -13.685102, states[40]= 0.000153
Saving checkpoint... 
Iteration: 1397830286, states[0] = 28.986772, states[40]= 0.347517
Saving checkpoint... 
Iteration: 1401608087, states[0] = 19.592963, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1406746910, states[0] = 29.851382, states[40]= 0.079998
Saving checkpoint... 
Iteration: 1411182879, states[0] = -67.687986, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1415348514, states[0] = -84.813447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419083379, states[0] = -84.806343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422955770, states[0] = -49.034835, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1425965827, states[0] = -84.752600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429500843, states[0] = 16.764393, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1434462868, states[0] = -57.730208, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1438022903, states[0] = -84.682544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441797681, states[0] = -84.810488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446075579, states[0] = -84.693836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1449354765, states[0] = 6.763572, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1452832976, states[0] = -21.815793, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1457025253, states[0] = -84.782023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461563486, states[0] = -84.488672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466148723, states[0] = -84.374209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469744222, states[0] = 20.303984, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1473833121, states[0] = -37.001838, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1478530038, states[0] = -84.515880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482441013, states[0] = -16.218861, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1487288290, states[0] = 16.794379, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1490903124, states[0] = -84.581161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495134940, states[0] = -70.571416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1499810115, states[0] = -84.547910, states[40]= 0.000001
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.720015
 - CaMKt in component CaMK (millimolar): 0.057190
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 7.021583
 - nass in component intracellular_ions (millimolar): 7.021763
 - ki in component intracellular_ions (millimolar): 144.551782
 - kss in component intracellular_ions (millimolar): 144.551749
 - cansr in component intracellular_ions (millimolar): 2.240693
 - cajsr in component intracellular_ions (millimolar): 1.848513
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010085
 - hf in component INa (dimensionless): 0.579188
 - hs in component INa (dimensionless): 0.578955
 - j in component INa (dimensionless): 0.577641
 - hsp in component INa (dimensionless): 0.331275
 - jp in component INa (dimensionless): 0.576250
 - mL in component INaL (dimensionless): 0.000343
 - hL in component INaL (dimensionless): 0.328433
 - hLp in component INaL (dimensionless): 0.141582
 - a in component Ito (dimensionless): 0.001239
 - iF in component Ito (dimensionless): 0.999224
 - iS in component Ito (dimensionless): 0.311865
 - ap in component Ito (dimensionless): 0.000631
 - iFp in component Ito (dimensionless): 0.999224
 - iSp in component Ito (dimensionless): 0.344482
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.819256
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991225
 - jca in component ICaL (dimensionless): 0.994715
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007737
 - xrf in component IKr (dimensionless): 0.001637
 - xrs in component IKr (dimensionless): 0.717543
 - xs1 in component IKs (dimensionless): 0.418227
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996748
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:26:46 (33851): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_810.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_810_0_r1968875870_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_810_0_r1968875870_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.020903
     * GNaL_b in INaL: 0.006856
     * Gto_b in Ito: 0.093584
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034085
     * GKs_b in IKs: 0.001863
     * GK1_b in IK1: 0.165725
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 68.373101
     * GKb_b in IKb: 0.003932
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038492
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1499810115
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.547910 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.720015
 - CaMKt in component CaMK (millimolar): 0.057190
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 7.021583
 - nass in component intracellular_ions (millimolar): 7.021763
 - ki in component intracellular_ions (millimolar): 144.551782
 - kss in component intracellular_ions (millimolar): 144.551749
 - cansr in component intracellular_ions (millimolar): 2.240693
 - cajsr in component intracellular_ions (millimolar): 1.848513
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010085
 - hf in component INa (dimensionless): 0.579188
 - hs in component INa (dimensionless): 0.578955
 - j in component INa (dimensionless): 0.577641
 - hsp in component INa (dimensionless): 0.331275
 - jp in component INa (dimensionless): 0.576250
 - mL in component INaL (dimensionless): 0.000343
 - hL in component INaL (dimensionless): 0.328433
 - hLp in component INaL (dimensionless): 0.141582
 - a in component Ito (dimensionless): 0.001239
 - iF in component Ito (dimensionless): 0.999224
 - iS in component Ito (dimensionless): 0.311865
 - ap in component Ito (dimensionless): 0.000631
 - iFp in component Ito (dimensionless): 0.999224
 - iSp in component Ito (dimensionless): 0.344482
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.819256
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991225
 - jca in component ICaL (dimensionless): 0.994715
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007737
 - xrf in component IKr (dimensionless): 0.001637
 - xrs in component IKr (dimensionless): 0.717543
 - xs1 in component IKs (dimensionless): 0.418227
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996748
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:29:50 (34904): called boinc_finish(0)

</stderr_txt>
]]>


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