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Task 54621724

Name HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_904_1
Workunit 25932589
Created 25 Jun 2024, 8:49:11 UTC
Sent 25 Jun 2024, 10:18:05 UTC
Report deadline 28 Jun 2024, 10:18:15 UTC
Received 28 Jun 2024, 11:08:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222504
Run time 1 hours 17 min 58 sec
CPU time 59 min 57 sec
Validate state Valid
Credit 42.01
Device peak FLOPS 4.94 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 6.87 MB
Peak swap size 32.99 GB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_904.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_904_1_r1358999303_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_904_1_r1358999303_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 109.215228
     * GNaL_b in INaL: 0.007658
     * Gto_b in Ito: 0.075671
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032805
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.150641
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.613997
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049451
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 30150461, states[0] = -84.624443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 63773495, states[0] = -84.580895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103565849, states[0] = 8.470529, states[40]= 0.000135
Saving checkpoint... 
Iteration: 143841426, states[0] = -14.026439, states[40]= 0.000309
Saving checkpoint... 
Iteration: 182015757, states[0] = 28.303972, states[40]= 0.000099
Saving checkpoint... 
Iteration: 222672881, states[0] = -79.793353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261619523, states[0] = -84.745739, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_904.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_904_1_r1358999303_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240625104704336441_ORdGradInc_k_24-Schmidt_575-conf_904_1_r1358999303_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 109.215228
     * GNaL_b in INaL: 0.007658
     * Gto_b in Ito: 0.075671
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032805
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.150641
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.613997
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049451
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 261619523
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.745739 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 282299801, states[0] = -84.688800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304776177, states[0] = 29.141544, states[40]= 0.000203
Saving checkpoint... 
Iteration: 330227814, states[0] = -84.176850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354568398, states[0] = -2.618456, states[40]= 0.000372
Saving checkpoint... 
Iteration: 381467156, states[0] = -84.610774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408186539, states[0] = -84.522147, states[40]= 0.000001
Saving checkpoint... 
Iteration: 433440989, states[0] = -84.180957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455691517, states[0] = 32.617879, states[40]= 0.516343
Saving checkpoint... 
Iteration: 481557617, states[0] = -84.741447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509288116, states[0] = -53.580034, states[40]= 0.000025
Saving checkpoint... 
Iteration: 536177329, states[0] = -84.726419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564204941, states[0] = -58.623361, states[40]= 0.000013
Saving checkpoint... 
Iteration: 601795174, states[0] = 13.377360, states[40]= 0.000063
Saving checkpoint... 
Iteration: 639142399, states[0] = 27.610536, states[40]= 0.000057
Saving checkpoint... 
Iteration: 676442040, states[0] = -84.602451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713503121, states[0] = -84.465201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750305462, states[0] = -84.478344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774942671, states[0] = -58.884812, states[40]= 0.000012
Saving checkpoint... 
Iteration: 800349876, states[0] = -84.578510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 825210297, states[0] = -6.937475, states[40]= 0.000394
Saving checkpoint... 
Iteration: 845329782, states[0] = -1.619559, states[40]= 0.000356
Saving checkpoint... 
Iteration: 869253976, states[0] = -72.987619, states[40]= 0.000002
Saving checkpoint... 
Iteration: 892733719, states[0] = 19.686660, states[40]= 0.000020
Saving checkpoint... 
Iteration: 915725598, states[0] = 23.808453, states[40]= 0.000011
Saving checkpoint... 
Iteration: 940278938, states[0] = -82.781102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964111466, states[0] = -51.663445, states[40]= 0.000031
Saving checkpoint... 
Iteration: 989156171, states[0] = -83.265981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012833096, states[0] = -84.655417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039355979, states[0] = 21.110680, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1065108124, states[0] = -84.407468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087018540, states[0] = -84.687067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1113398538, states[0] = -84.337164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141043376, states[0] = -84.595805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166511778, states[0] = -52.011765, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1192612646, states[0] = 10.438094, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1218248540, states[0] = -37.021241, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1244437346, states[0] = -67.694983, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1269427031, states[0] = -40.952271, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1293461008, states[0] = -84.728328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320985771, states[0] = -84.418212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346848285, states[0] = -84.328934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374904371, states[0] = -1.254377, states[40]= 0.000349
Saving checkpoint... 
Iteration: 1402075156, states[0] = -84.501704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429270367, states[0] = -33.421369, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1454856897, states[0] = -32.316040, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1476777571, states[0] = -84.143046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497973711, states[0] = -22.813530, states[40]= 0.000232
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.602188
 - CaMKt in component CaMK (millimolar): 0.054045
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.917393
 - nass in component intracellular_ions (millimolar): 6.917568
 - ki in component intracellular_ions (millimolar): 144.687507
 - kss in component intracellular_ions (millimolar): 144.687477
 - cansr in component intracellular_ions (millimolar): 2.205190
 - cajsr in component intracellular_ions (millimolar): 1.834479
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010205
 - hf in component INa (dimensionless): 0.574461
 - hs in component INa (dimensionless): 0.574210
 - j in component INa (dimensionless): 0.572791
 - hsp in component INa (dimensionless): 0.326946
 - jp in component INa (dimensionless): 0.571224
 - mL in component INaL (dimensionless): 0.000351
 - hL in component INaL (dimensionless): 0.320232
 - hLp in component INaL (dimensionless): 0.136031
 - a in component Ito (dimensionless): 0.001248
 - iF in component Ito (dimensionless): 0.999208
 - iS in component Ito (dimensionless): 0.305429
 - ap in component Ito (dimensionless): 0.000636
 - iFp in component Ito (dimensionless): 0.999208
 - iSp in component Ito (dimensionless): 0.335812
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.813156
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990305
 - jca in component ICaL (dimensionless): 0.994340
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007635
 - xrf in component IKr (dimensionless): 0.001996
 - xrs in component IKr (dimensionless): 0.729000
 - xs1 in component IKs (dimensionless): 0.425686
 - xs2 in component IKs (dimensionless): 0.000288
 - xk1 in component IK1 (dimensionless): 0.996778
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
19:07:48 (1827): called boinc_finish(0)

</stderr_txt>
]]>