𝕏

Task 54607446

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-BASE_MID-conf_494_1
Workunit 25927674
Created 24 Jun 2024, 17:35:37 UTC
Sent 25 Jun 2024, 8:40:09 UTC
Report deadline 28 Jun 2024, 8:40:09 UTC
Received 28 Jun 2024, 2:01:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221437
Run time 2 hours 13 min 58 sec
CPU time 2 hours 3 min 16 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 2.62 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.64 MB
Peak swap size 6.21 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-BASE_MID-conf_494.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-BASE_MID-conf_494_1_r346988042_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-BASE_MID-conf_494_1_r346988042_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 117.982663
     * GNaL_b in INaL: 0.007732
     * Gto_b in Ito: 0.077794
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033877
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.146503
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 63.432861
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045879
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9923788, states[0] = -86.709376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 20379427, states[0] = -86.696060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 30461831, states[0] = -86.798571, states[40]= 0.000002
Saving checkpoint... 
Iteration: 40743341, states[0] = -86.294655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50897238, states[0] = -86.796113, states[40]= 0.000002
Saving checkpoint... 
Iteration: 60984219, states[0] = -86.875235, states[40]= 0.000002
Saving checkpoint... 
Iteration: 71136251, states[0] = -18.976368, states[40]= 0.000172
Saving checkpoint... 
Iteration: 80641728, states[0] = -24.070024, states[40]= 0.000302
Saving checkpoint... 
Iteration: 90979181, states[0] = -86.905184, states[40]= 0.000002
Saving checkpoint... 
Iteration: 101068408, states[0] = 20.111700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 111346387, states[0] = -86.781592, states[40]= 0.000002
Saving checkpoint... 
Iteration: 121769241, states[0] = -86.536675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131278155, states[0] = -86.580882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141691445, states[0] = -79.215985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152111127, states[0] = -1.407327, states[40]= 0.000101
Saving checkpoint... 
Iteration: 162012177, states[0] = 29.657990, states[40]= -0.000000
Saving checkpoint... 
Iteration: 172317061, states[0] = -86.722472, states[40]= 0.000002
Saving checkpoint... 
Iteration: 182632085, states[0] = -18.372950, states[40]= 0.000172
Saving checkpoint... 
Iteration: 193112134, states[0] = -2.192412, states[40]= 0.000110
Saving checkpoint... 
Iteration: 203547014, states[0] = 27.628430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213702987, states[0] = -85.768180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224041814, states[0] = 29.100293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234575470, states[0] = 16.816395, states[40]= 0.000003
Saving checkpoint... 
Iteration: 244704107, states[0] = -85.861976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255220636, states[0] = -86.214161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265320855, states[0] = -86.730216, states[40]= 0.000002
Saving checkpoint... 
Iteration: 275771355, states[0] = -86.550329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285992344, states[0] = -86.926481, states[40]= 0.000002
Saving checkpoint... 
Iteration: 296468048, states[0] = -86.915552, states[40]= 0.000002
Saving checkpoint... 
Iteration: 306752128, states[0] = -86.443958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 316405577, states[0] = -86.869851, states[40]= 0.000002
Saving checkpoint... 
Iteration: 326811933, states[0] = -86.702155, states[40]= 0.000002
Saving checkpoint... 
Iteration: 337319314, states[0] = -86.722386, states[40]= 0.000002
Saving checkpoint... 
Iteration: 347800857, states[0] = -86.666145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357878939, states[0] = -86.836715, states[40]= 0.000002
Saving checkpoint... 
Iteration: 368310096, states[0] = -86.694461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 378611517, states[0] = -1.829355, states[40]= 0.000106
Saving checkpoint... 
Iteration: 388883075, states[0] = -86.840494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 398992638, states[0] = -86.920654, states[40]= 0.000002
Saving checkpoint... 
Iteration: 409265114, states[0] = -86.511805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419476279, states[0] = -86.912907, states[40]= 0.000002
Saving checkpoint... 
Iteration: 429705589, states[0] = -85.939079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439948806, states[0] = -86.897368, states[40]= 0.000002
Saving checkpoint... 
Iteration: 449803631, states[0] = -86.669805, states[40]= 0.000002
Saving checkpoint... 
Iteration: 460008002, states[0] = 26.427099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470374266, states[0] = -86.824252, states[40]= 0.000002
Saving checkpoint... 
Iteration: 480732574, states[0] = -86.300188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491131225, states[0] = -17.735657, states[40]= 0.000164
Saving checkpoint... 
Iteration: 501596714, states[0] = 6.686882, states[40]= 0.000031
Saving checkpoint... 
Iteration: 511683115, states[0] = -68.169406, states[40]= 0.000008
Saving checkpoint... 
Iteration: 520430494, states[0] = -86.880631, states[40]= 0.000002
Saving checkpoint... 
Iteration: 529935220, states[0] = -86.883584, states[40]= 0.000002
Saving checkpoint... 
Iteration: 540187472, states[0] = -74.417502, states[40]= 0.000003
Saving checkpoint... 
Iteration: 550811423, states[0] = -86.688564, states[40]= 0.000002
Saving checkpoint... 
Iteration: 561269574, states[0] = -86.526162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571502485, states[0] = 22.090794, states[40]= 1.518470
Saving checkpoint... 
Iteration: 581885383, states[0] = -86.833112, states[40]= 0.000002
Saving checkpoint... 
Iteration: 592111450, states[0] = -1.774955, states[40]= 0.000105
Saving checkpoint... 
Iteration: 602362319, states[0] = -86.799008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 612301089, states[0] = -86.652623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622694697, states[0] = -82.998207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632642408, states[0] = -26.893515, states[40]= 0.000384
Saving checkpoint... 
Iteration: 642193314, states[0] = -81.831287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650351180, states[0] = -86.777068, states[40]= 0.000002
Saving checkpoint... 
Iteration: 657562481, states[0] = 22.212766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666939922, states[0] = -86.879548, states[40]= 0.000002
Saving checkpoint... 
Iteration: 676704953, states[0] = -85.889452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685194944, states[0] = -83.166798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692964620, states[0] = -86.892786, states[40]= 0.000002
Saving checkpoint... 
Iteration: 702619968, states[0] = -8.030379, states[40]= 0.000145
Saving checkpoint... 
Iteration: 709753152, states[0] = -86.428101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 716969254, states[0] = -86.893814, states[40]= 0.000002
Saving checkpoint... 
Iteration: 719152662, states[0] = -35.603151, states[40]= 0.000344
Saving checkpoint... 
Iteration: 722992168, states[0] = -86.903252, states[40]= 0.000002
Saving checkpoint... 
Iteration: 730046149, states[0] = 27.888186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735720941, states[0] = -86.190369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742077009, states[0] = 16.140034, states[40]= 0.000004
Saving checkpoint... 
Iteration: 747391140, states[0] = -86.831225, states[40]= 0.000002
Saving checkpoint... 
Iteration: 753255161, states[0] = -86.437705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759565352, states[0] = 21.079926, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769963876, states[0] = -86.888285, states[40]= 0.000002
Saving checkpoint... 
Iteration: 780684038, states[0] = -69.401977, states[40]= 0.000007
Saving checkpoint... 
Iteration: 791598737, states[0] = 5.636344, states[40]= 0.000038
Saving checkpoint... 
Iteration: 802596550, states[0] = 6.781173, states[40]= 0.000031
Saving checkpoint... 
Iteration: 812663518, states[0] = -45.916977, states[40]= 0.000139
Saving checkpoint... 
Iteration: 823488073, states[0] = -86.896355, states[40]= 0.000002
Saving checkpoint... 
Iteration: 834315183, states[0] = -86.684178, states[40]= 0.000002
Saving checkpoint... 
Iteration: 844985849, states[0] = -86.894329, states[40]= 0.000002
Saving checkpoint... 
Iteration: 855568183, states[0] = 19.929713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865592135, states[0] = 9.022343, states[40]= 0.000020
Saving checkpoint... 
Iteration: 875086701, states[0] = 11.669491, states[40]= 0.000011
Saving checkpoint... 
Iteration: 884735904, states[0] = -86.302886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894267411, states[0] = -86.497178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 903234750, states[0] = -86.293309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912323769, states[0] = -86.703118, states[40]= 0.000002
Saving checkpoint... 
Iteration: 921791854, states[0] = -86.603010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930868692, states[0] = -86.791424, states[40]= 0.000002
Saving checkpoint... 
Iteration: 940477374, states[0] = -86.885688, states[40]= 0.000002
Saving checkpoint... 
Iteration: 949290030, states[0] = -86.594574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958779325, states[0] = -86.549996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968652195, states[0] = -35.165325, states[40]= 0.000352
Saving checkpoint... 
Iteration: 978310365, states[0] = -86.662331, states[40]= 0.000002
Saving checkpoint... 
Iteration: 988068806, states[0] = 19.674769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 996970917, states[0] = -86.879733, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1007880675, states[0] = -86.804290, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1018599177, states[0] = 5.410442, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1029352169, states[0] = -86.758583, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1039957540, states[0] = -86.870541, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1049613078, states[0] = -2.843492, states[40]= 0.000115
Saving checkpoint... 
Iteration: 1060255323, states[0] = -86.421846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071061800, states[0] = 22.485440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081861429, states[0] = -86.771854, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1092645229, states[0] = -29.170533, states[40]= 0.000411
Saving checkpoint... 
Iteration: 1103584823, states[0] = 12.565505, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1114277635, states[0] = -86.534063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125129666, states[0] = -16.340878, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1135663301, states[0] = -45.667209, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1146379072, states[0] = -86.794736, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157296876, states[0] = -86.608610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168183628, states[0] = -68.754968, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1178973768, states[0] = -86.871376, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1189875494, states[0] = -86.787494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1200893374, states[0] = -86.809623, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1211465138, states[0] = -86.865479, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1222367452, states[0] = -86.773947, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1233313532, states[0] = -86.657947, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1244228180, states[0] = -86.223383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254974409, states[0] = -86.867638, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1265812582, states[0] = -86.653420, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1276662486, states[0] = -44.839286, states[40]= 0.000155
Saving checkpoint... 
Iteration: 1287607395, states[0] = 0.801596, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1298639541, states[0] = -24.535406, states[40]= 0.000320
Saving checkpoint... 
Iteration: 1309393408, states[0] = -86.803875, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1320156455, states[0] = -39.019641, states[40]= 0.000266
Saving checkpoint... 
Iteration: 1330702618, states[0] = -85.657301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341550241, states[0] = 26.625130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352449609, states[0] = -86.849308, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1363333094, states[0] = -86.701476, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1374297060, states[0] = -86.597519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385134979, states[0] = -20.829009, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1395980783, states[0] = -86.862966, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1405929097, states[0] = -86.832419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1413717613, states[0] = -86.121381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424288336, states[0] = -86.562254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434887291, states[0] = -86.789918, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1445798032, states[0] = -86.597083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455991835, states[0] = -86.864197, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1466855667, states[0] = -86.741436, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1477455820, states[0] = -86.846309, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1488223922, states[0] = -86.174591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498939025, states[0] = -86.834665, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.740645
 - CaMKt in component CaMK (millimolar): 0.025328
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.297110
 - nass in component intracellular_ions (millimolar): 8.297263
 - ki in component intracellular_ions (millimolar): 143.113383
 - kss in component intracellular_ions (millimolar): 143.113344
 - cansr in component intracellular_ions (millimolar): 2.063603
 - cajsr in component intracellular_ions (millimolar): 1.999438
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008233
 - hf in component INa (dimensionless): 0.657338
 - hs in component INa (dimensionless): 0.657305
 - j in component INa (dimensionless): 0.657117
 - hsp in component INa (dimensionless): 0.409085
 - jp in component INa (dimensionless): 0.656982
 - mL in component INaL (dimensionless): 0.000234
 - hL in component INaL (dimensionless): 0.453885
 - hLp in component INaL (dimensionless): 0.220828
 - a in component Ito (dimensionless): 0.001081
 - iF in component Ito (dimensionless): 0.999456
 - iS in component Ito (dimensionless): 0.535628
 - ap in component Ito (dimensionless): 0.000551
 - iFp in component Ito (dimensionless): 0.999456
 - iSp in component Ito (dimensionless): 0.579014
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.879020
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999632
 - jca in component ICaL (dimensionless): 0.999943
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003908
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.508770
 - xs1 in component IKs (dimensionless): 0.330090
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997046
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
22:01:30 (1148): called boinc_finish(0)

</stderr_txt>
]]>


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