𝕏

Task 54601248

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1
Workunit 25924577
Created 24 Jun 2024, 17:32:55 UTC
Sent 25 Jun 2024, 7:58:32 UTC
Report deadline 28 Jun 2024, 7:58:32 UTC
Received 25 Jun 2024, 12:16:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 1 hours 58 min 8 sec
CPU time 1 hours 9 min 28 sec
Validate state Valid
Credit 45.34
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.59 MB
Peak swap size 391.88 GB
Peak disk usage 1.56 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 23769953, states[0] = -94.696083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46816092, states[0] = -94.638411, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 46816092
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.638411 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 93965084, states[0] = -94.611866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130482232, states[0] = -94.581848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154515847, states[0] = -94.597309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175754082, states[0] = -94.611054, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 175754082
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.611054 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 223343948, states[0] = -94.610208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229089264, states[0] = -94.598816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286328480, states[0] = -94.601975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317406685, states[0] = -94.592177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340227187, states[0] = -94.228691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362857782, states[0] = -94.499786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390997100, states[0] = -94.607612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417350191, states[0] = -94.592330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441539142, states[0] = -94.598790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465617414, states[0] = -94.602659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489597241, states[0] = -94.593711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513888129, states[0] = -94.600795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535171150, states[0] = -60.918862, states[40]= 0.000016
Saving checkpoint... 
Iteration: 557709988, states[0] = -94.137471, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 557709988
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.137471 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 576906124, states[0] = -94.595032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602456228, states[0] = -94.591719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621588316, states[0] = -94.598090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643636793, states[0] = -94.604927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665574088, states[0] = -94.597434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687797775, states[0] = -94.414637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709369742, states[0] = -94.595252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731368867, states[0] = -94.600956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753132716, states[0] = -94.603826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775299015, states[0] = -94.416894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795906325, states[0] = -94.608733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819543887, states[0] = -94.593871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841595147, states[0] = -94.597881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863536584, states[0] = -94.606630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885505435, states[0] = -94.583477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907570919, states[0] = 13.679525, states[40]= 0.004497
Saving checkpoint... 
Iteration: 928901015, states[0] = -94.600362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952904989, states[0] = -94.539195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973615198, states[0] = -94.605130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995918670, states[0] = -94.608459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016777067, states[0] = -94.595888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037617417, states[0] = -13.236684, states[40]= 0.001951
Saving checkpoint... 
Iteration: 1058902864, states[0] = -94.600260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079679216, states[0] = -94.592859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100414897, states[0] = -94.545465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121265715, states[0] = -94.602375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140682243, states[0] = -94.606681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164047750, states[0] = -94.598258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185723533, states[0] = -94.608121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203882062, states[0] = -94.600481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224006873, states[0] = -94.598737, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_1_r1313136562_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1224006873
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.598737 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1248922457, states[0] = -94.599866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269912350, states[0] = -94.591527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290768970, states[0] = -94.608870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311952015, states[0] = -94.594245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333464636, states[0] = -94.607587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354076522, states[0] = -94.597800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374296846, states[0] = -94.595497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398043946, states[0] = -94.591985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419031418, states[0] = -94.598311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439920051, states[0] = -94.591392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460474637, states[0] = -94.573528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481303297, states[0] = -94.601544, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.466979
 - CaMKt in component CaMK (millimolar): 0.001081
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.349988
 - nass in component intracellular_ions (millimolar): 6.350071
 - ki in component intracellular_ions (millimolar): 145.581541
 - kss in component intracellular_ions (millimolar): 145.581530
 - cansr in component intracellular_ions (millimolar): 1.540228
 - cajsr in component intracellular_ions (millimolar): 1.540224
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003781
 - hf in component INa (dimensionless): 0.872246
 - hs in component INa (dimensionless): 0.872246
 - j in component INa (dimensionless): 0.872247
 - hsp in component INa (dimensionless): 0.711410
 - jp in component INa (dimensionless): 0.872248
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.717553
 - hLp in component INaL (dimensionless): 0.525997
 - a in component Ito (dimensionless): 0.000642
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.997818
 - ap in component Ito (dimensionless): 0.000327
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.999285
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998880
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002819
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001733
 - xs1 in component IKs (dimensionless): 0.022320
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997449
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:52:12 (31995): called boinc_finish(0)

</stderr_txt>
]]>