𝕏

Task 54601247

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0
Workunit 25924577
Created 24 Jun 2024, 17:32:55 UTC
Sent 25 Jun 2024, 7:57:33 UTC
Report deadline 28 Jun 2024, 7:57:33 UTC
Received 28 Jun 2024, 17:10:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239969
Run time 1 hours 25 min 11 sec
CPU time 1 hours 16 min 26 sec
Validate state Valid
Credit 45.34
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.18 MB
Peak swap size 5.32 MB
Peak disk usage 1.55 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 22061779, states[0] = -94.695375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43312931, states[0] = -94.656154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63011177, states[0] = -94.611479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83839711, states[0] = -94.617072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104431436, states[0] = -94.604375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125919786, states[0] = -94.614471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145708090, states[0] = -94.611732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165576944, states[0] = -94.600304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186638134, states[0] = -94.599133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207244124, states[0] = -94.593842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227088359, states[0] = -94.594453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248162472, states[0] = -94.606497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261950876, states[0] = -94.595106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281857392, states[0] = -94.595756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296192010, states[0] = -94.604241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316633980, states[0] = -94.597816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336850007, states[0] = -94.595678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357583832, states[0] = 8.135240, states[40]= 0.004851
Saving checkpoint... 
Iteration: 377760778, states[0] = -94.331350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398041428, states[0] = -94.592093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418280731, states[0] = -94.609491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439148546, states[0] = -94.597522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458533173, states[0] = -94.606931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478242369, states[0] = -94.608958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498318460, states[0] = -94.609553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517307742, states[0] = -94.592480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537494549, states[0] = -94.591590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553738045, states[0] = -94.603177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573696762, states[0] = -94.603887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593543530, states[0] = -94.606663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607601884, states[0] = -1.541311, states[40]= 0.004343
Saving checkpoint... 
Iteration: 621459281, states[0] = -94.599720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638176819, states[0] = -94.606716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657587072, states[0] = 6.597093, states[40]= 0.004878
Saving checkpoint... 
Iteration: 665225054, states[0] = -94.221140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678242092, states[0] = -94.608835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693876240, states[0] = -94.600866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711985733, states[0] = -94.594345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725678343, states[0] = -94.606740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746003749, states[0] = -94.607278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761615430, states[0] = -94.597696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769546352, states[0] = -94.593884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783620474, states[0] = -94.605144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789625410, states[0] = -94.593356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804858243, states[0] = -94.592057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823820356, states[0] = -94.601655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843334367, states[0] = -94.609313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851340535, states[0] = -94.601321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865170126, states[0] = -59.860151, states[40]= 0.000019
Saving checkpoint... 
Iteration: 876691788, states[0] = -94.596805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889425519, states[0] = -94.594696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909137253, states[0] = -94.597366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925584617, states[0] = -94.598727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944175652, states[0] = -94.596933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963497027, states[0] = -94.607267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978025223, states[0] = -94.588332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997670486, states[0] = -60.230437, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1016793264, states[0] = -94.595739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035045063, states[0] = 22.523611, states[40]= 0.003101
Saving checkpoint... 
Iteration: 1054522590, states[0] = -94.593881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073795318, states[0] = -94.601912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092484004, states[0] = -94.591310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112301557, states[0] = -94.592163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130815430, states[0] = -94.609184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143751826, states[0] = -94.602596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162253200, states[0] = -94.592391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178825827, states[0] = -94.601360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197552244, states[0] = 20.310844, states[40]= 0.003515
Saving checkpoint... 
Iteration: 1215951412, states[0] = -94.607862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234603358, states[0] = -94.593235, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1234603358
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.593235 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1248165436, states[0] = -94.605760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261976782, states[0] = -94.594089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274727378, states[0] = -94.592468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295132925, states[0] = -26.170768, states[40]= 0.001469
Saving checkpoint... 
Iteration: 1315057895, states[0] = 18.453360, states[40]= 0.003847


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1315057895
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 18.453360 (After loading)
 - states[40]: 0.003847 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1329888198, states[0] = -94.591606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339909350, states[0] = -94.591500, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Coppini_5000-conf_788_0_r1182239654_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.615027
     * GNaL_b in INaL: 0.007388
     * Gto_b in Ito: 0.066206
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034093
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.166359
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 65.608859
     * GKb_b in IKb: 0.004007
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046991
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1339909350
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.591500 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1360869539, states[0] = -94.608791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374062624, states[0] = -94.597954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395350178, states[0] = -94.490926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415571882, states[0] = -94.596674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435404783, states[0] = -94.538774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455720401, states[0] = -94.607880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476897597, states[0] = -94.594574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491635125, states[0] = -94.597049, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.466979
 - CaMKt in component CaMK (millimolar): 0.001081
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.349988
 - nass in component intracellular_ions (millimolar): 6.350071
 - ki in component intracellular_ions (millimolar): 145.581541
 - kss in component intracellular_ions (millimolar): 145.581530
 - cansr in component intracellular_ions (millimolar): 1.540228
 - cajsr in component intracellular_ions (millimolar): 1.540224
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003781
 - hf in component INa (dimensionless): 0.872246
 - hs in component INa (dimensionless): 0.872246
 - j in component INa (dimensionless): 0.872247
 - hsp in component INa (dimensionless): 0.711410
 - jp in component INa (dimensionless): 0.872248
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.717553
 - hLp in component INaL (dimensionless): 0.525997
 - a in component Ito (dimensionless): 0.000642
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.997818
 - ap in component Ito (dimensionless): 0.000327
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.999285
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998880
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002819
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001733
 - xs1 in component IKs (dimensionless): 0.022320
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997449
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:10:10 (16996): called boinc_finish(0)

</stderr_txt>
]]>