𝕏

Task 54597948

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85_0
Workunit 25922928
Created 24 Jun 2024, 17:31:26 UTC
Sent 25 Jun 2024, 7:46:45 UTC
Report deadline 28 Jun 2024, 10:39:33 UTC
Received 29 Jun 2024, 3:03:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227484
Run time 2 hours 14 min 44 sec
CPU time 1 hours 59 min 20 sec
Validate state Valid
Credit 45.79
Device peak FLOPS 4.67 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.69 MB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85_0_r55880910_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85_0_r55880910_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 111.522218
     * GNaL_b in INaL: 0.007222
     * Gto_b in Ito: 0.085485
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032135
     * GKs_b in IKs: 0.001807
     * GK1_b in IK1: 0.042739
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 68.008941
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051535
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13516703, states[0] = 27.614552, states[40]= 0.006649
Saving checkpoint... 
Iteration: 26778963, states[0] = -91.484743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40256904, states[0] = -90.901186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53492540, states[0] = -92.098294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67327280, states[0] = -91.693684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80502448, states[0] = 40.999024, states[40]= 0.458975
Saving checkpoint... 
Iteration: 94423417, states[0] = -91.963196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108042782, states[0] = 20.888887, states[40]= 0.002342
Saving checkpoint... 
Iteration: 122252939, states[0] = -90.552510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136116938, states[0] = -26.884086, states[40]= 0.001140
Saving checkpoint... 
Iteration: 149293301, states[0] = -91.385771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162858122, states[0] = -91.774119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176786445, states[0] = -91.305661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190589323, states[0] = -1.518287, states[40]= 0.004373
Saving checkpoint... 
Iteration: 204174490, states[0] = -72.021938, states[40]= 0.000002
Saving checkpoint... 
Iteration: 217905608, states[0] = -91.902302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231279858, states[0] = -91.214428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244282672, states[0] = -91.253987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257782476, states[0] = -91.251087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271202004, states[0] = -82.915154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284480946, states[0] = -91.998971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298032150, states[0] = 24.589043, states[40]= 0.001783
Saving checkpoint... 
Iteration: 311128246, states[0] = -37.341432, states[40]= 0.000496
Saving checkpoint... 
Iteration: 324006020, states[0] = 29.401702, states[40]= 0.178387
Saving checkpoint... 
Iteration: 337450431, states[0] = -91.970488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350822490, states[0] = -91.602522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364599540, states[0] = -10.064258, states[40]= 0.002641
Saving checkpoint... 
Iteration: 377967087, states[0] = -91.987192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391511472, states[0] = 28.133797, states[40]= 0.029324
Saving checkpoint... 
Iteration: 405018981, states[0] = 27.781387, states[40]= 0.003493
Saving checkpoint... 
Iteration: 418649077, states[0] = -56.021031, states[40]= 0.000032
Saving checkpoint... 
Iteration: 432108861, states[0] = -19.133496, states[40]= 0.001331
Saving checkpoint... 
Iteration: 445702427, states[0] = -83.042366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459605196, states[0] = -15.546709, states[40]= 0.001655
Saving checkpoint... 
Iteration: 473502425, states[0] = 41.152550, states[40]= 0.456331
Saving checkpoint... 
Iteration: 487625529, states[0] = -34.821081, states[40]= 0.000656
Saving checkpoint... 
Iteration: 501054586, states[0] = 16.408490, states[40]= 0.003230
Saving checkpoint... 
Iteration: 514661811, states[0] = -65.027691, states[40]= 0.000006
Saving checkpoint... 
Iteration: 528434161, states[0] = -91.948909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541220410, states[0] = -87.380643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554524485, states[0] = 26.738939, states[40]= 0.001798
Saving checkpoint... 
Iteration: 567735277, states[0] = -89.372429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580857658, states[0] = -91.766144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594014517, states[0] = 28.147680, states[40]= 0.011206
Saving checkpoint... 
Iteration: 607624742, states[0] = -34.090783, states[40]= 0.000706


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85_0_r55880910_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85_0_r55880910_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 111.522218
     * GNaL_b in INaL: 0.007222
     * Gto_b in Ito: 0.085485
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032135
     * GKs_b in IKs: 0.001807
     * GK1_b in IK1: 0.042739
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 68.008941
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051535
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 607624742
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -34.090783 (After loading)
 - states[40]: 0.000706 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 620453214, states[0] = -91.972348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632995630, states[0] = -92.006819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645865152, states[0] = -91.792285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658796997, states[0] = -91.412590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672142138, states[0] = -50.138347, states[40]= 0.000084
Saving checkpoint... 
Iteration: 684838718, states[0] = -91.686628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697887110, states[0] = -91.856794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711197781, states[0] = -81.553294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723874398, states[0] = -91.821348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736835655, states[0] = -91.671682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749974744, states[0] = -91.992088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762901233, states[0] = -91.889797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776282570, states[0] = -91.249588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789033266, states[0] = 24.232404, states[40]= 0.001827
Saving checkpoint... 
Iteration: 802611479, states[0] = -21.658652, states[40]= 0.001241
Saving checkpoint... 
Iteration: 815614368, states[0] = -24.405343, states[40]= 0.001200
Saving checkpoint... 
Iteration: 829354888, states[0] = -91.754657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842289522, states[0] = -91.335168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855553454, states[0] = 16.859958, states[40]= 0.003140
Saving checkpoint... 
Iteration: 869028474, states[0] = 25.696804, states[40]= 0.001690
Saving checkpoint... 
Iteration: 881585992, states[0] = 0.784527, states[40]= 0.004607
Saving checkpoint... 
Iteration: 894363562, states[0] = -91.785806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907201254, states[0] = -82.677383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919719481, states[0] = -87.209625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932395809, states[0] = -91.876968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945309499, states[0] = -91.514571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959143626, states[0] = -51.449415, states[40]= 0.000068
Saving checkpoint... 
Iteration: 972401352, states[0] = -91.889153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984212359, states[0] = -85.719122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995788764, states[0] = -91.325877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007069482, states[0] = 9.931962, states[40]= 0.004309
Saving checkpoint... 
Iteration: 1019041160, states[0] = 21.512185, states[40]= 0.002248


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85_0_r55880910_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-CLVPET_Block_K1_75-conf_85_0_r55880910_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 111.522218
     * GNaL_b in INaL: 0.007222
     * Gto_b in Ito: 0.085485
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032135
     * GKs_b in IKs: 0.001807
     * GK1_b in IK1: 0.042739
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 68.008941
     * GKb_b in IKb: 0.003781
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051535
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1019041160
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 21.512185 (After loading)
 - states[40]: 0.002248 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1031370569, states[0] = -91.808248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044208590, states[0] = -84.784017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056133939, states[0] = -42.625573, states[40]= 0.000252
Saving checkpoint... 
Iteration: 1069308940, states[0] = -91.509914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081403703, states[0] = -91.893674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093754492, states[0] = -90.588540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105909438, states[0] = -91.905144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118028110, states[0] = 25.799871, states[40]= 0.001688
Saving checkpoint... 
Iteration: 1130597733, states[0] = -8.385268, states[40]= 0.003021
Saving checkpoint... 
Iteration: 1143431708, states[0] = -91.942740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156091930, states[0] = -3.463742, states[40]= 0.004071
Saving checkpoint... 
Iteration: 1168900883, states[0] = -91.887296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181618150, states[0] = -27.955077, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1194011354, states[0] = 28.131934, states[40]= 0.030473
Saving checkpoint... 
Iteration: 1206302628, states[0] = -91.459846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218279176, states[0] = -91.198820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231034042, states[0] = 23.979517, states[40]= 0.001861
Saving checkpoint... 
Iteration: 1244343014, states[0] = -91.703851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256847833, states[0] = -91.724585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269276967, states[0] = -91.163937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281928814, states[0] = -91.937829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294999047, states[0] = -92.005882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307862688, states[0] = -91.781000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321265104, states[0] = -90.923525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334625392, states[0] = -34.691494, states[40]= 0.000664
Saving checkpoint... 
Iteration: 1347644025, states[0] = -51.795649, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1360569558, states[0] = 9.896135, states[40]= 0.004313
Saving checkpoint... 
Iteration: 1373489863, states[0] = -92.000199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385429645, states[0] = -91.938642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398719108, states[0] = -87.137121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411266593, states[0] = -90.959448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423943720, states[0] = -91.957798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437069813, states[0] = 9.774105, states[40]= 0.004328
Saving checkpoint... 
Iteration: 1449196882, states[0] = -81.244613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461748297, states[0] = -90.303826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473986879, states[0] = -91.997846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486832173, states[0] = -91.650910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499174093, states[0] = -71.812658, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1511390707, states[0] = -70.154439, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1523610205, states[0] = -89.895055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536074196, states[0] = -91.851791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548423949, states[0] = -66.707106, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1561294463, states[0] = -89.669663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574031007, states[0] = 25.142531, states[40]= 0.001383
Saving checkpoint... 
Iteration: 1586493332, states[0] = -90.069500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598415125, states[0] = -89.758397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611154775, states[0] = -89.569845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623221402, states[0] = -89.297692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636089231, states[0] = -88.905064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648918819, states[0] = -88.615831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661934855, states[0] = -88.371877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674744274, states[0] = -88.247531, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -88.071590
 - CaMKt in component CaMK (millimolar): 0.001081
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.185090
 - nass in component intracellular_ions (millimolar): 6.185173
 - ki in component intracellular_ions (millimolar): 145.720672
 - kss in component intracellular_ions (millimolar): 145.720660
 - cansr in component intracellular_ions (millimolar): 1.532979
 - cajsr in component intracellular_ions (millimolar): 1.533050
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.007202
 - hf in component INa (dimensionless): 0.704773
 - hs in component INa (dimensionless): 0.704780
 - j in component INa (dimensionless): 0.704816
 - hsp in component INa (dimensionless): 0.462944
 - jp in component INa (dimensionless): 0.704837
 - mL in component INaL (dimensionless): 0.000181
 - hL in component INaL (dimensionless): 0.519868
 - hLp in component INaL (dimensionless): 0.322009
 - a in component Ito (dimensionless): 0.000988
 - iF in component Ito (dimensionless): 0.999569
 - iS in component Ito (dimensionless): 0.995674
 - ap in component Ito (dimensionless): 0.000503
 - iFp in component Ito (dimensionless): 0.999569
 - iSp in component Ito (dimensionless): 0.997849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998832
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002759
 - xrf in component IKr (dimensionless): 0.000008
 - xrs in component IKr (dimensionless): 0.006853
 - xs1 in component IKs (dimensionless): 0.023941
 - xs2 in component IKs (dimensionless): 0.000189
 - xk1 in component IK1 (dimensionless): 0.998645
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:02:58 (1953): called boinc_finish(0)

</stderr_txt>
]]>


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