𝕏

Task 54593147

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1
Workunit 25920583
Created 24 Jun 2024, 17:29:25 UTC
Sent 25 Jun 2024, 7:04:11 UTC
Report deadline 28 Jun 2024, 7:04:11 UTC
Received 25 Jun 2024, 10:55:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 1 hours 51 min 53 sec
CPU time 1 hours 7 min 53 sec
Validate state Valid
Credit 46.63
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.80 MB
Peak swap size 391.88 GB
Peak disk usage 0.19 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.884906
     * GNaL_b in INaL: 0.007231
     * Gto_b in Ito: 0.073431
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033680
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.159515
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 61.805918
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037612
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 28759256, states[0] = 25.009447, states[40]= 0.053117
Saving checkpoint... 
Iteration: 54487518, states[0] = -87.474616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79198272, states[0] = -87.413904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101583900, states[0] = -29.887588, states[40]= 0.000464
Saving checkpoint... 
Iteration: 126529292, states[0] = 17.556937, states[40]= 0.006977
Saving checkpoint... 
Iteration: 148208199, states[0] = -87.433705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169727623, states[0] = -87.464440, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.884906
     * GNaL_b in INaL: 0.007231
     * Gto_b in Ito: 0.073431
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033680
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.159515
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 61.805918
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037612
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 169727623
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.464440 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 217592281, states[0] = -40.320844, states[40]= 0.000130
Saving checkpoint... 
Iteration: 253051822, states[0] = 4.382266, states[40]= 0.005631
Saving checkpoint... 
Iteration: 275438160, states[0] = -87.394034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295239317, states[0] = -87.479801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312546185, states[0] = 8.101856, states[40]= 0.005930
Saving checkpoint... 
Iteration: 335768643, states[0] = 22.068962, states[40]= 0.010928
Saving checkpoint... 
Iteration: 358724312, states[0] = -87.459554, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.884906
     * GNaL_b in INaL: 0.007231
     * Gto_b in Ito: 0.073431
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033680
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.159515
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 61.805918
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037612
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 358724312
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.459554 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 405799236, states[0] = 6.135187, states[40]= 0.005783
Saving checkpoint... 
Iteration: 442235906, states[0] = -87.475349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466248154, states[0] = -87.489968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487122529, states[0] = -82.822636, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.884906
     * GNaL_b in INaL: 0.007231
     * Gto_b in Ito: 0.073431
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033680
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.159515
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 61.805918
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037612
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 487122529
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -82.822636 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 536111581, states[0] = -66.627767, states[40]= 0.000002


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pieske_500-conf_380_1_r2068996032_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.884906
     * GNaL_b in INaL: 0.007231
     * Gto_b in Ito: 0.073431
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033680
     * GKs_b in IKs: 0.001916
     * GK1_b in IK1: 0.159515
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 61.805918
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037612
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 536111581
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -66.627767 (After loading)
 - states[40]: 0.000002 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 538872727, states[0] = -83.016947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596252650, states[0] = 35.556344, states[40]= 0.133682
Saving checkpoint... 
Iteration: 626936347, states[0] = -87.389582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649416730, states[0] = -87.340218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672566187, states[0] = -8.128691, states[40]= 0.003290
Saving checkpoint... 
Iteration: 696866145, states[0] = -73.910773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722811836, states[0] = -3.648449, states[40]= 0.004383
Saving checkpoint... 
Iteration: 747411640, states[0] = -87.325573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771845695, states[0] = -44.657120, states[40]= 0.000070
Saving checkpoint... 
Iteration: 796166205, states[0] = -87.338586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820528617, states[0] = 17.880945, states[40]= 0.007062
Saving checkpoint... 
Iteration: 843171055, states[0] = -87.351765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862067883, states[0] = -10.059945, states[40]= 0.002810
Saving checkpoint... 
Iteration: 884164254, states[0] = -87.332976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906421759, states[0] = -87.353559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928850716, states[0] = -51.232122, states[40]= 0.000026
Saving checkpoint... 
Iteration: 951599425, states[0] = -49.518474, states[40]= 0.000034
Saving checkpoint... 
Iteration: 973917869, states[0] = -87.342997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997004510, states[0] = 29.545516, states[40]= 0.139044
Saving checkpoint... 
Iteration: 1019260851, states[0] = 24.438964, states[40]= 0.037175
Saving checkpoint... 
Iteration: 1040871127, states[0] = -81.266444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064047247, states[0] = 7.428750, states[40]= 0.005881
Saving checkpoint... 
Iteration: 1085845459, states[0] = -44.353480, states[40]= 0.000073
Saving checkpoint... 
Iteration: 1107932053, states[0] = -87.379101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130924202, states[0] = -87.359675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153399007, states[0] = -87.284015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174917507, states[0] = -87.341770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196693798, states[0] = -87.405082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218264889, states[0] = 23.275405, states[40]= 0.017266
Saving checkpoint... 
Iteration: 1241298476, states[0] = 6.634957, states[40]= 0.005822
Saving checkpoint... 
Iteration: 1263382208, states[0] = -86.912437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284911970, states[0] = -87.325924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306539327, states[0] = 12.212970, states[40]= 0.006235
Saving checkpoint... 
Iteration: 1328341339, states[0] = -39.139561, states[40]= 0.000153
Saving checkpoint... 
Iteration: 1349749772, states[0] = -87.490754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370931560, states[0] = -87.377630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390384817, states[0] = -87.090872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412551575, states[0] = 4.554261, states[40]= 0.005647
Saving checkpoint... 
Iteration: 1434891683, states[0] = -87.242265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455362800, states[0] = -68.527092, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1478230943, states[0] = -87.467630, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.366586
 - CaMKt in component CaMK (millimolar): 0.020208
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 6.991367
 - nass in component intracellular_ions (millimolar): 6.991468
 - ki in component intracellular_ions (millimolar): 144.960363
 - kss in component intracellular_ions (millimolar): 144.960336
 - cansr in component intracellular_ions (millimolar): 1.448044
 - cajsr in component intracellular_ions (millimolar): 1.226987
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.007731
 - hf in component INa (dimensionless): 0.680119
 - hs in component INa (dimensionless): 0.680018
 - j in component INa (dimensionless): 0.679339
 - hsp in component INa (dimensionless): 0.433912
 - jp in component INa (dimensionless): 0.677531
 - mL in component INaL (dimensionless): 0.000207
 - hL in component INaL (dimensionless): 0.391801
 - hLp in component INaL (dimensionless): 0.184833
 - a in component Ito (dimensionless): 0.001036
 - iF in component Ito (dimensionless): 0.999512
 - iS in component Ito (dimensionless): 0.296374
 - ap in component Ito (dimensionless): 0.000528
 - iFp in component Ito (dimensionless): 0.999512
 - iSp in component Ito (dimensionless): 0.344755
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.856493
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991047
 - jca in component ICaL (dimensionless): 0.991628
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004373
 - xrf in component IKr (dimensionless): 0.001639
 - xrs in component IKr (dimensionless): 0.673861
 - xs1 in component IKs (dimensionless): 0.381860
 - xs2 in component IKs (dimensionless): 0.000212
 - xk1 in component IK1 (dimensionless): 0.996893
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:00:05 (30474): called boinc_finish(0)

</stderr_txt>
]]>