𝕏

Task 54584931

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172_1
Workunit 25916481
Created 24 Jun 2024, 17:25:53 UTC
Sent 25 Jun 2024, 6:02:04 UTC
Report deadline 28 Jun 2024, 6:02:04 UTC
Received 27 Jun 2024, 2:33:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215309
Run time 2 hours 30 min 19 sec
CPU time 1 hours 38 min 54 sec
Validate state Valid
Credit 44.59
Device peak FLOPS 3.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 13.71 MB
Peak swap size 8.56 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172_1_r1621341098_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172_1_r1621341098_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.993077
     * GNaL_b in INaL: 0.006349
     * Gto_b in Ito: 0.091030
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031960
     * GKs_b in IKs: 0.001823
     * GK1_b in IK1: 0.037261
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.871190
     * GKb_b in IKb: 0.004048
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035366
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15272370, states[0] = -90.991980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30430026, states[0] = -91.688159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44919268, states[0] = -91.552126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60098853, states[0] = -10.478991, states[40]= 0.002417
Saving checkpoint... 
Iteration: 75216620, states[0] = -84.807184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90048252, states[0] = 18.311118, states[40]= 0.002227
Saving checkpoint... 
Iteration: 104771051, states[0] = -90.073140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119910882, states[0] = -91.366627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135054563, states[0] = 15.913301, states[40]= 0.002700
Saving checkpoint... 
Iteration: 150325701, states[0] = -90.960975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165542082, states[0] = 20.670649, states[40]= 0.001849
Saving checkpoint... 
Iteration: 180494142, states[0] = -91.469287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195599737, states[0] = -10.769809, states[40]= 0.002364
Saving checkpoint... 
Iteration: 210925524, states[0] = -91.377539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225996154, states[0] = -91.467339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240826507, states[0] = -90.957208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255838414, states[0] = -91.044048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270795217, states[0] = -90.597908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285990017, states[0] = -91.461479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301141992, states[0] = -50.586487, states[40]= 0.000072
Saving checkpoint... 
Iteration: 316193414, states[0] = -78.466698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325317075, states[0] = -90.872201, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172_1_r1621341098_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172_1_r1621341098_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.993077
     * GNaL_b in INaL: 0.006349
     * Gto_b in Ito: 0.091030
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031960
     * GKs_b in IKs: 0.001823
     * GK1_b in IK1: 0.037261
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.871190
     * GKb_b in IKb: 0.004048
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035366
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 325317075
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -90.872201 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 331745876, states[0] = -88.614992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338936620, states[0] = -91.395958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350666733, states[0] = -67.568882, states[40]= 0.000003
Saving checkpoint... 
Iteration: 365652560, states[0] = -58.920778, states[40]= 0.000017
Saving checkpoint... 
Iteration: 381024522, states[0] = 26.183546, states[40]= 0.001438
Saving checkpoint... 
Iteration: 396259246, states[0] = -89.513274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407063609, states[0] = 12.181929, states[40]= 0.003398
Saving checkpoint... 
Iteration: 411737409, states[0] = -87.783925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423817301, states[0] = -90.873805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435792449, states[0] = -90.549675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444238629, states[0] = -87.918474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458597975, states[0] = -9.086914, states[40]= 0.002713
Saving checkpoint... 
Iteration: 473783148, states[0] = -90.361334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486929050, states[0] = -91.381258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500070037, states[0] = 9.260564, states[40]= 0.003843
Saving checkpoint... 
Iteration: 514538550, states[0] = 21.941116, states[40]= 0.001660
Saving checkpoint... 
Iteration: 529128647, states[0] = -38.461718, states[40]= 0.000398
Saving checkpoint... 
Iteration: 541859761, states[0] = -91.162665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554458202, states[0] = -91.427441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568624929, states[0] = -35.001735, states[40]= 0.000591
Saving checkpoint... 
Iteration: 581630109, states[0] = -39.818155, states[40]= 0.000336
Saving checkpoint... 
Iteration: 595803532, states[0] = -90.717560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610077827, states[0] = 5.304215, states[40]= 0.004227
Saving checkpoint... 
Iteration: 624010936, states[0] = 27.268570, states[40]= 0.034650
Saving checkpoint... 
Iteration: 632563723, states[0] = 12.132601, states[40]= 0.003407
Saving checkpoint... 
Iteration: 645036331, states[0] = 22.708086, states[40]= 0.001554
Saving checkpoint... 
Iteration: 657317981, states[0] = -90.879146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670968824, states[0] = -91.439560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685282001, states[0] = -90.333058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699450674, states[0] = -91.416480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712100074, states[0] = -11.078445, states[40]= 0.002303
Saving checkpoint... 
Iteration: 723327872, states[0] = -90.964804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732313278, states[0] = -90.831585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741207355, states[0] = -82.427937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752649951, states[0] = -57.016054, states[40]= 0.000024
Saving checkpoint... 
Iteration: 762579360, states[0] = 4.456640, states[40]= 0.004269
Saving checkpoint... 
Iteration: 772306280, states[0] = -90.751645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780529308, states[0] = 24.936247, states[40]= 0.001325
Saving checkpoint... 
Iteration: 793633029, states[0] = -42.518882, states[40]= 0.000235
Saving checkpoint... 
Iteration: 806939932, states[0] = -91.399293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821296486, states[0] = -90.614866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832038554, states[0] = 21.940107, states[40]= 0.001660
Saving checkpoint... 
Iteration: 843524400, states[0] = 26.211948, states[40]= 0.001448
Saving checkpoint... 
Iteration: 851338425, states[0] = -91.040556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861509825, states[0] = 27.193572, states[40]= 0.050205
Saving checkpoint... 
Iteration: 869657331, states[0] = -62.133550, states[40]= 0.000010
Saving checkpoint... 
Iteration: 879508763, states[0] = 27.170634, states[40]= 0.071694
Saving checkpoint... 
Iteration: 891051607, states[0] = 17.099834, states[40]= 0.002484
Saving checkpoint... 
Iteration: 904782077, states[0] = -90.333660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918314745, states[0] = -90.845847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932420297, states[0] = -91.361136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945514892, states[0] = 27.442853, states[40]= 0.009656
Saving checkpoint... 
Iteration: 957296677, states[0] = -90.617145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969453517, states[0] = -91.419181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980260714, states[0] = -89.584560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988399032, states[0] = -91.307600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998009713, states[0] = 27.187992, states[40]= 0.052123
Saving checkpoint... 
Iteration: 1010326520, states[0] = -90.952517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022477779, states[0] = -91.447070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035253729, states[0] = -89.189442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049210521, states[0] = -83.191144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062993147, states[0] = -91.459861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077186956, states[0] = -76.278361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087899159, states[0] = -91.307479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097704619, states[0] = -81.724416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109950383, states[0] = -91.414077, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172_1_r1621341098_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-TESZT_Block_K1_75-conf_172_1_r1621341098_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 102.993077
     * GNaL_b in INaL: 0.006349
     * Gto_b in Ito: 0.091030
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031960
     * GKs_b in IKs: 0.001823
     * GK1_b in IK1: 0.037261
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.871190
     * GKb_b in IKb: 0.004048
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035366
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1109950383
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -91.414077 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1114831528, states[0] = -90.990869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115347375, states[0] = -91.094530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115455792, states[0] = -91.421566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115564145, states[0] = 11.948826, states[40]= 0.003438
Saving checkpoint... 
Iteration: 1115828475, states[0] = -90.967574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116218785, states[0] = -84.957203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117568736, states[0] = 9.874375, states[40]= 0.003760
Saving checkpoint... 
Iteration: 1119973177, states[0] = -91.442029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121422688, states[0] = -91.365335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121993797, states[0] = -91.460054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123028720, states[0] = 25.104572, states[40]= 0.001319
Saving checkpoint... 
Iteration: 1123137161, states[0] = -46.300840, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1123228318, states[0] = -86.590826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126040316, states[0] = 21.316747, states[40]= 0.001752
Saving checkpoint... 
Iteration: 1130904099, states[0] = -91.320964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144345624, states[0] = -91.084160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158677071, states[0] = -72.429676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173182442, states[0] = -74.603477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179731940, states[0] = -87.104284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179886194, states[0] = -91.266633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180281108, states[0] = -90.308501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183185860, states[0] = -75.883091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190028018, states[0] = 25.300290, states[40]= 0.001317
Saving checkpoint... 
Iteration: 1203115590, states[0] = -26.219667, states[40]= 0.001069
Saving checkpoint... 
Iteration: 1217143584, states[0] = -51.938921, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1228878461, states[0] = -91.238849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243109362, states[0] = -20.229229, states[40]= 0.001201
Saving checkpoint... 
Iteration: 1256581175, states[0] = 3.417721, states[40]= 0.004300
Saving checkpoint... 
Iteration: 1264601240, states[0] = -12.208924, states[40]= 0.002087
Saving checkpoint... 
Iteration: 1275008514, states[0] = 27.179906, states[40]= 0.077948
Saving checkpoint... 
Iteration: 1287580087, states[0] = 4.046064, states[40]= 0.004284
Saving checkpoint... 
Iteration: 1299800469, states[0] = -90.671959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311111469, states[0] = -22.276262, states[40]= 0.001144
Saving checkpoint... 
Iteration: 1321452041, states[0] = -91.415421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331708147, states[0] = -82.619992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341441586, states[0] = -91.399438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352426809, states[0] = -91.372661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360132245, states[0] = -41.792762, states[40]= 0.000259
Saving checkpoint... 
Iteration: 1370021039, states[0] = 26.878799, states[40]= 0.002094
Saving checkpoint... 
Iteration: 1381520473, states[0] = 26.969772, states[40]= 0.002310
Saving checkpoint... 
Iteration: 1395434248, states[0] = -91.386573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408319956, states[0] = -90.893821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417225125, states[0] = -86.088130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425865703, states[0] = -91.185805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432437201, states[0] = -91.391618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441854632, states[0] = -91.132582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456111652, states[0] = -22.452417, states[40]= 0.001141
Saving checkpoint... 
Iteration: 1470656561, states[0] = -61.634570, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1485100572, states[0] = -11.557496, states[40]= 0.002209
Saving checkpoint... 
Iteration: 1495543012, states[0] = 20.342110, states[40]= 0.001906
Saving checkpoint... 
Iteration: 1499520325, states[0] = 26.992575, states[40]= 0.002374
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -91.338392
 - CaMKt in component CaMK (millimolar): 0.012456
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.584502
 - nass in component intracellular_ions (millimolar): 6.584597
 - ki in component intracellular_ions (millimolar): 145.300911
 - kss in component intracellular_ions (millimolar): 145.300889
 - cansr in component intracellular_ions (millimolar): 1.642048
 - cajsr in component intracellular_ions (millimolar): 1.599406
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005184
 - hf in component INa (dimensionless): 0.803279
 - hs in component INa (dimensionless): 0.803237
 - j in component INa (dimensionless): 0.802944
 - hsp in component INa (dimensionless): 0.595634
 - jp in component INa (dimensionless): 0.802714
 - mL in component INaL (dimensionless): 0.000098
 - hL in component INaL (dimensionless): 0.589694
 - hLp in component INaL (dimensionless): 0.311793
 - a in component Ito (dimensionless): 0.000793
 - iF in component Ito (dimensionless): 0.999757
 - iS in component Ito (dimensionless): 0.574097
 - ap in component Ito (dimensionless): 0.000404
 - iFp in component Ito (dimensionless): 0.999757
 - iSp in component Ito (dimensionless): 0.629335
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915121
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999831
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002937
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.438956
 - xs1 in component IKs (dimensionless): 0.271803
 - xs2 in component IKs (dimensionless): 0.000131
 - xk1 in component IK1 (dimensionless): 0.998129
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:32:54 (6652): called boinc_finish(0)

</stderr_txt>
]]>


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