𝕏

Task 54581289

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969_1
Workunit 25914660
Created 24 Jun 2024, 17:24:14 UTC
Sent 25 Jun 2024, 5:51:09 UTC
Report deadline 28 Jun 2024, 5:51:09 UTC
Received 25 Jun 2024, 9:05:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 1 hours 58 min 32 sec
CPU time 1 hours 58 min 32 sec
Validate state Valid
Credit 41.91
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969_1_r902140418_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969_1_r902140418_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 112.750450
     * GNaL_b in INaL: 0.008880
     * Gto_b in Ito: 0.085204
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032742
     * GKs_b in IKs: 0.001848
     * GK1_b in IK1: 0.145117
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 64.295291
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036641
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12491875, states[0] = -94.345174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26189052, states[0] = -29.633083, states[40]= 0.014906
Saving checkpoint... 
Iteration: 38458319, states[0] = -94.410989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51058977, states[0] = 27.740456, states[40]= 0.000004
Saving checkpoint... 
Iteration: 64603671, states[0] = 8.693803, states[40]= 0.001833
Saving checkpoint... 
Iteration: 77790211, states[0] = -94.020454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90448819, states[0] = -94.512546, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102873634, states[0] = -94.416626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116210291, states[0] = -52.716713, states[40]= 0.002086
Saving checkpoint... 
Iteration: 129417583, states[0] = -94.503202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142947077, states[0] = -94.535253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156052308, states[0] = 28.723841, states[40]= 0.000004
Saving checkpoint... 
Iteration: 168644619, states[0] = -19.802676, states[40]= 0.012880
Saving checkpoint... 
Iteration: 180691436, states[0] = -40.832211, states[40]= 0.008282
Saving checkpoint... 
Iteration: 192797639, states[0] = -94.123387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205020680, states[0] = 35.016385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218469645, states[0] = -94.549555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231789497, states[0] = -94.061705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245635172, states[0] = -13.618771, states[40]= 0.007082
Saving checkpoint... 
Iteration: 259263155, states[0] = -93.805879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 272600973, states[0] = 8.158494, states[40]= 0.003122
Saving checkpoint... 
Iteration: 284950365, states[0] = -94.530013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298320301, states[0] = -94.243559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311591785, states[0] = 12.528234, states[40]= 0.001227
Saving checkpoint... 
Iteration: 324552855, states[0] = 28.483569, states[40]= 0.000004
Saving checkpoint... 
Iteration: 335895948, states[0] = -94.461775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349206231, states[0] = -50.878819, states[40]= 0.002731
Saving checkpoint... 
Iteration: 361798981, states[0] = -94.115251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373853168, states[0] = -94.361146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 386675301, states[0] = -32.997630, states[40]= 0.016739
Saving checkpoint... 
Iteration: 399879352, states[0] = -94.423819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413525495, states[0] = 34.934580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425465493, states[0] = -94.524558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438944593, states[0] = -94.508119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450864497, states[0] = -94.383852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463189208, states[0] = -39.705642, states[40]= 0.009252
Saving checkpoint... 
Iteration: 475596288, states[0] = 10.430452, states[40]= 0.001972
Saving checkpoint... 
Iteration: 489437825, states[0] = -94.496516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503257211, states[0] = -93.678962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515758823, states[0] = -93.710843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528870566, states[0] = -94.389821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540956540, states[0] = -94.505715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554826193, states[0] = -94.241702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568515262, states[0] = 34.162563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582170281, states[0] = -30.997528, states[40]= 0.019537
Saving checkpoint... 
Iteration: 595734265, states[0] = -78.722833, states[40]= 0.000048
Saving checkpoint... 
Iteration: 608181013, states[0] = -35.512182, states[40]= 0.013535
Saving checkpoint... 
Iteration: 622017537, states[0] = 34.691597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634264830, states[0] = -93.784163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646383811, states[0] = -94.404953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658661781, states[0] = -27.832123, states[40]= 0.023673
Saving checkpoint... 
Iteration: 669164059, states[0] = -28.675594, states[40]= 0.022749
Saving checkpoint... 
Iteration: 680468489, states[0] = -94.497698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692657606, states[0] = -26.229756, states[40]= 0.024460
Saving checkpoint... 
Iteration: 705290145, states[0] = -94.013449, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969_1_r902140418_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969_1_r902140418_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 112.750450
     * GNaL_b in INaL: 0.008880
     * Gto_b in Ito: 0.085204
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032742
     * GKs_b in IKs: 0.001848
     * GK1_b in IK1: 0.145117
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 64.295291
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036641
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 705290145
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.013449 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 716303080, states[0] = -94.101245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 728894756, states[0] = -94.415492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742678236, states[0] = -34.253341, states[40]= 0.015056
Saving checkpoint... 
Iteration: 754353098, states[0] = -94.317948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765359695, states[0] = -94.335551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778832684, states[0] = -94.243895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790808929, states[0] = -94.127927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804733126, states[0] = -77.029803, states[40]= 0.000061
Saving checkpoint... 
Iteration: 817210742, states[0] = -54.351504, states[40]= 0.001737
Saving checkpoint... 
Iteration: 828916184, states[0] = -94.435209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842619227, states[0] = -2.012017, states[40]= 0.008752
Saving checkpoint... 
Iteration: 856219877, states[0] = -61.879379, states[40]= 0.000600
Saving checkpoint... 
Iteration: 869778313, states[0] = -93.896890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883328410, states[0] = -94.214239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 894256594, states[0] = -93.620073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907886029, states[0] = -94.379673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920875751, states[0] = -94.357298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933997049, states[0] = -94.482608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947533051, states[0] = 33.945017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959532692, states[0] = 34.011495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973112756, states[0] = 1.972567, states[40]= 0.007069
Saving checkpoint... 
Iteration: 985613931, states[0] = 1.289926, states[40]= 0.007450
Saving checkpoint... 
Iteration: 998513740, states[0] = 33.652657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011617495, states[0] = -0.881918, states[40]= 0.008431
Saving checkpoint... 
Iteration: 1025060737, states[0] = 25.679517, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1035824603, states[0] = -94.180056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047183440, states[0] = -36.697680, states[40]= 0.012151
Saving checkpoint... 
Iteration: 1059419323, states[0] = -94.413008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072262771, states[0] = -93.708475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1085272657, states[0] = -93.818218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1095729843, states[0] = -72.422186, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1109389258, states[0] = -94.362949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121331013, states[0] = -94.198102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135034375, states[0] = 33.697421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147980625, states[0] = -94.451645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159099676, states[0] = 8.844490, states[40]= 0.002657
Saving checkpoint... 
Iteration: 1169806622, states[0] = -94.071436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1183544784, states[0] = 31.096092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195399736, states[0] = -94.370933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1208496349, states[0] = -94.451657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220609895, states[0] = 3.599501, states[40]= 0.005996
Saving checkpoint... 
Iteration: 1231970490, states[0] = -94.436966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244934019, states[0] = -94.408038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257926029, states[0] = -94.398342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271053009, states[0] = 28.477607, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1284946514, states[0] = -94.414517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298370626, states[0] = -94.303101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311084196, states[0] = 16.017148, states[40]= 0.000475
Saving checkpoint... 
Iteration: 1323929362, states[0] = -94.394366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336045735, states[0] = 30.823019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349323405, states[0] = -94.139175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363234365, states[0] = -78.975130, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1377159670, states[0] = -27.009681, states[40]= 0.024063
Saving checkpoint... 
Iteration: 1389475556, states[0] = -94.421867, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969_1_r902140418_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_1000-conf_969_1_r902140418_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 112.750450
     * GNaL_b in INaL: 0.008880
     * Gto_b in Ito: 0.085204
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032742
     * GKs_b in IKs: 0.001848
     * GK1_b in IK1: 0.145117
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 64.295291
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036641
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1389475556
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.421867 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1400670412, states[0] = -31.053814, states[40]= 0.019325
Saving checkpoint... 
Iteration: 1411397609, states[0] = -94.343144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424341006, states[0] = -94.202339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437009582, states[0] = 31.253948, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1449530840, states[0] = 34.351356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461452287, states[0] = -94.399143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474659088, states[0] = -26.780451, states[40]= 0.024131
Saving checkpoint... 
Iteration: 1487529080, states[0] = 34.611142, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.296038
 - CaMKt in component CaMK (millimolar): 0.064116
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 8.794353
 - nass in component intracellular_ions (millimolar): 8.794552
 - ki in component intracellular_ions (millimolar): 141.994765
 - kss in component intracellular_ions (millimolar): 141.994725
 - cansr in component intracellular_ions (millimolar): 2.908811
 - cajsr in component intracellular_ions (millimolar): 2.852548
 - cai in component intracellular_ions (millimolar): 0.000108
 - m in component INa (dimensionless): 0.003847
 - hf in component INa (dimensionless): 0.869085
 - hs in component INa (dimensionless): 0.869070
 - j in component INa (dimensionless): 0.868960
 - hsp in component INa (dimensionless): 0.705518
 - jp in component INa (dimensionless): 0.868872
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.663717
 - hLp in component INaL (dimensionless): 0.369224
 - a in component Ito (dimensionless): 0.000649
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.533127
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.592690
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.859667
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999430
 - jca in component ICaL (dimensionless): 0.999918
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005804
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.464294
 - xs1 in component IKs (dimensionless): 0.348617
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997492
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:44:34 (13448): called boinc_finish(0)

</stderr_txt>
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