𝕏

Task 54513740

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105_0
Workunit 25880944
Created 24 Jun 2024, 16:53:55 UTC
Sent 24 Jun 2024, 23:00:51 UTC
Report deadline 27 Jun 2024, 23:00:51 UTC
Received 26 Jun 2024, 16:27:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236149
Run time 1 hours 28 min 55 sec
CPU time 1 hours 26 min 12 sec
Validate state Valid
Credit 44.08
Device peak FLOPS 5.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.19 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105_0_r859730464_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105_0_r859730464_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.926903
     * GNaL_b in INaL: 0.005730
     * Gto_b in Ito: 0.085940
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033945
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.165306
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 64.175396
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035402
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 4163306, states[0] = -53.508122, states[40]= 0.000030
Saving checkpoint... 
Iteration: 14340772, states[0] = -94.151191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28230727, states[0] = -93.734079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37684281, states[0] = -94.188549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51737089, states[0] = -94.185141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61227583, states[0] = -94.201380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70054979, states[0] = 23.550662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83667725, states[0] = -94.198519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97085767, states[0] = -94.220832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111144387, states[0] = -94.222153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124618498, states[0] = -94.241919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133471625, states[0] = -94.215266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147334865, states[0] = -94.220632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160951353, states[0] = -94.236490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175052941, states[0] = -94.232574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189031919, states[0] = -94.233823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203081093, states[0] = -94.231904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217143241, states[0] = -94.229450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231069872, states[0] = -94.232411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245136560, states[0] = -94.229616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258821923, states[0] = -94.243249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272959540, states[0] = -94.236932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286927871, states[0] = -94.238224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297711296, states[0] = -94.212579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311511311, states[0] = -94.216925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325642605, states[0] = -94.213657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339582860, states[0] = -94.214819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353759097, states[0] = -94.210918, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105_0_r859730464_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105_0_r859730464_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.926903
     * GNaL_b in INaL: 0.005730
     * Gto_b in Ito: 0.085940
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033945
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.165306
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 64.175396
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035402
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 353759097
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.210918 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 367349306, states[0] = -94.220726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381299063, states[0] = -94.222130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394951002, states[0] = -94.235753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408091610, states[0] = 7.204490, states[40]= 0.000071
Saving checkpoint... 
Iteration: 422316413, states[0] = -94.061241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435814304, states[0] = -94.208780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450035316, states[0] = 26.029163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458795806, states[0] = -94.241725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472691704, states[0] = -94.244418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486844899, states[0] = -94.239296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500636497, states[0] = -94.243777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514751194, states[0] = -94.242536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528708090, states[0] = -94.243414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542574540, states[0] = -94.239784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556320459, states[0] = -94.068073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570504432, states[0] = -94.228021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584555118, states[0] = -94.237077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598429269, states[0] = -94.197375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612709547, states[0] = -94.242226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626038040, states[0] = 25.941231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639983802, states[0] = -94.203220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653667238, states[0] = -94.208627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667445022, states[0] = -94.213804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681288210, states[0] = -94.218354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695350092, states[0] = -94.216180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709068991, states[0] = -94.226221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722801458, states[0] = -94.237865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737118977, states[0] = -94.223777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750612433, states[0] = -94.239505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764648529, states[0] = -94.240360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777931798, states[0] = -94.202097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791600678, states[0] = -94.208183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805564926, states[0] = -94.208826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819198513, states[0] = -94.219587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832986463, states[0] = -94.228112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846758081, states[0] = -94.237738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860958952, states[0] = -94.228968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874170720, states[0] = -80.280135, states[40]= 0.000002
Saving checkpoint... 
Iteration: 888310819, states[0] = -94.042023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902342036, states[0] = -94.103257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916360923, states[0] = -94.130722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929905409, states[0] = -94.200414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943802963, states[0] = -94.201967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957687278, states[0] = -94.204009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971513970, states[0] = -94.207786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985608488, states[0] = -94.205328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999091124, states[0] = -94.221304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012857822, states[0] = -94.231483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026290339, states[0] = -93.985508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040538472, states[0] = -94.228424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053826653, states[0] = -94.200028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067714916, states[0] = -94.201929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081493943, states[0] = -94.206781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095465169, states[0] = -94.207348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109776688, states[0] = -94.200157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122982347, states[0] = -94.224303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136840168, states[0] = -94.230549, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105_0_r859730464_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_EPI_4000-conf_105_0_r859730464_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.926903
     * GNaL_b in INaL: 0.005730
     * Gto_b in Ito: 0.085940
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033945
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.165306
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 64.175396
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035402
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1136840168
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.230549 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1150676349, states[0] = -94.235198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164509543, states[0] = -94.221076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178777986, states[0] = -94.232485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192569021, states[0] = -94.230294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206298208, states[0] = -94.005568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220118941, states[0] = -16.006888, states[40]= 0.000264
Saving checkpoint... 
Iteration: 1234085262, states[0] = 10.781972, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1247537889, states[0] = -94.203377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256478589, states[0] = -94.211001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270589866, states[0] = -94.231030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279358040, states[0] = -94.207880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288379632, states[0] = -94.147662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301828964, states[0] = -94.196564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310844260, states[0] = -94.227973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318918837, states[0] = -94.224495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332145617, states[0] = -46.854579, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1340876938, states[0] = -94.226103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354789333, states[0] = -94.229635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368125967, states[0] = -23.870883, states[40]= 0.000345
Saving checkpoint... 
Iteration: 1381819196, states[0] = -94.195625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390918714, states[0] = -94.223505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399461161, states[0] = -94.203256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413729096, states[0] = -94.196866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422637132, states[0] = -94.231093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431406396, states[0] = -94.204344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440105451, states[0] = -2.384604, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1448910802, states[0] = -94.223074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457870242, states[0] = -94.193700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466550472, states[0] = -94.224324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479430213, states[0] = -94.203004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488380217, states[0] = -94.145508, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.067070
 - CaMKt in component CaMK (millimolar): 0.002454
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 7.385363
 - nass in component intracellular_ions (millimolar): 7.385507
 - ki in component intracellular_ions (millimolar): 144.259920
 - kss in component intracellular_ions (millimolar): 144.259904
 - cansr in component intracellular_ions (millimolar): 2.502306
 - cajsr in component intracellular_ions (millimolar): 2.502876
 - cai in component intracellular_ions (millimolar): 0.000109
 - m in component INa (dimensionless): 0.003937
 - hf in component INa (dimensionless): 0.864743
 - hs in component INa (dimensionless): 0.864744
 - j in component INa (dimensionless): 0.864747
 - hsp in component INa (dimensionless): 0.697737
 - jp in component INa (dimensionless): 0.864749
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706636
 - hLp in component INaL (dimensionless): 0.512385
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996901
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006021
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006514
 - xs1 in component IKs (dimensionless): 0.038316
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997548
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:51:02 (195455): called boinc_finish(0)

</stderr_txt>
]]>


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