𝕏

Task 54511145

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_802_1
Workunit 25879646
Created 24 Jun 2024, 16:52:46 UTC
Sent 24 Jun 2024, 22:46:47 UTC
Report deadline 28 Jun 2024, 8:22:47 UTC
Received 25 Jun 2024, 15:37:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232784
Run time 1 hours 5 min 36 sec
CPU time 56 min 9 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.22 MB
Peak swap size 5.28 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_802.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_802_1_r231493950_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_802_1_r231493950_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.176132
     * GNaL_b in INaL: 0.007359
     * Gto_b in Ito: 0.093351
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032234
     * GKs_b in IKs: 0.001820
     * GK1_b in IK1: 0.171505
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 61.719267
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040398
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16884558, states[0] = -95.037981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34158325, states[0] = -82.462480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51035563, states[0] = 17.307643, states[40]= 0.005259
Saving checkpoint... 
Iteration: 67979425, states[0] = -95.046196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85261835, states[0] = -94.945188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102118116, states[0] = -32.986217, states[40]= 0.000370
Saving checkpoint... 
Iteration: 119060403, states[0] = 8.419809, states[40]= 0.004803
Saving checkpoint... 
Iteration: 136271507, states[0] = -94.954444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153082680, states[0] = -2.570339, states[40]= 0.003842
Saving checkpoint... 
Iteration: 170119618, states[0] = -34.339927, states[40]= 0.000313
Saving checkpoint... 
Iteration: 187308555, states[0] = -94.985576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204084827, states[0] = -3.971159, states[40]= 0.003586
Saving checkpoint... 
Iteration: 221133858, states[0] = -48.646290, states[40]= 0.000039
Saving checkpoint... 
Iteration: 238356600, states[0] = -95.012191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255201381, states[0] = -94.850676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272322643, states[0] = -94.994625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289476596, states[0] = -95.043383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306344795, states[0] = -95.006677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323408209, states[0] = -95.029873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340517454, states[0] = 21.531398, states[40]= 0.012121
Saving checkpoint... 
Iteration: 357371344, states[0] = -95.018076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374410357, states[0] = -95.030402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391542131, states[0] = 15.216800, states[40]= 0.004988
Saving checkpoint... 
Iteration: 408383492, states[0] = -95.022378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425524717, states[0] = 20.268684, states[40]= 0.006727
Saving checkpoint... 
Iteration: 442631044, states[0] = -45.628951, states[40]= 0.000063
Saving checkpoint... 
Iteration: 459482373, states[0] = -95.044042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476716261, states[0] = -94.878344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493728016, states[0] = -94.898005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510576944, states[0] = 0.791075, states[40]= 0.004326
Saving checkpoint... 
Iteration: 527851884, states[0] = -95.009855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544820732, states[0] = -94.993243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561672457, states[0] = -94.475918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578944541, states[0] = -95.037904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595900345, states[0] = -95.027489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612706594, states[0] = -94.860508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630024121, states[0] = 20.396053, states[40]= 0.006909
Saving checkpoint... 
Iteration: 646878258, states[0] = -95.020390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663935706, states[0] = -95.036090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680865839, states[0] = -95.015695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696823084, states[0] = -94.994568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713414631, states[0] = -95.031245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730832607, states[0] = -95.000036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747689575, states[0] = -94.825323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764534770, states[0] = 17.606683, states[40]= 0.005310
Saving checkpoint... 
Iteration: 781894026, states[0] = -95.025478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798659676, states[0] = -83.992594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815451316, states[0] = -95.038975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832788280, states[0] = -94.969299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849623565, states[0] = -38.083535, states[40]= 0.000190
Saving checkpoint... 
Iteration: 866441780, states[0] = -95.037158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883858750, states[0] = -95.012619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900586334, states[0] = -5.013288, states[40]= 0.003379
Saving checkpoint... 
Iteration: 917355293, states[0] = -95.011093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934752747, states[0] = -94.932428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951544514, states[0] = 14.391918, states[40]= 0.004935
Saving checkpoint... 
Iteration: 968423476, states[0] = -95.033188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985791047, states[0] = -94.971525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002702532, states[0] = -94.852367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019559791, states[0] = 8.678780, states[40]= 0.004808
Saving checkpoint... 
Iteration: 1036967541, states[0] = -95.041493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053778452, states[0] = -94.960264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070646227, states[0] = -62.918862, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1088028240, states[0] = 19.438890, states[40]= 0.005981
Saving checkpoint... 
Iteration: 1104874438, states[0] = -95.018670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121755399, states[0] = -94.935523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139161430, states[0] = -87.011189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156010136, states[0] = 22.513159, states[40]= 0.052184
Saving checkpoint... 
Iteration: 1172863110, states[0] = -95.014225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190171846, states[0] = -94.404265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207010333, states[0] = 22.466391, states[40]= 0.049724
Saving checkpoint... 
Iteration: 1223856743, states[0] = -95.011499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241298467, states[0] = -94.977294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258127208, states[0] = -41.674146, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1274932348, states[0] = -95.034930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292298450, states[0] = -94.977243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309159948, states[0] = -84.479143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326024498, states[0] = 20.316127, states[40]= 0.006791
Saving checkpoint... 
Iteration: 1343423392, states[0] = -95.032889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360268924, states[0] = -94.950536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377061648, states[0] = 7.923254, states[40]= 0.004790
Saving checkpoint... 
Iteration: 1394447252, states[0] = -95.037804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411280736, states[0] = -94.962138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428054883, states[0] = 10.601368, states[40]= 0.004839
Saving checkpoint... 
Iteration: 1445444614, states[0] = -95.037271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461659160, states[0] = -83.053726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478484761, states[0] = -95.043595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495903338, states[0] = -95.027665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512762769, states[0] = -95.067544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529568276, states[0] = -95.100164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546868245, states[0] = -2.444917, states[40]= 0.004378
Saving checkpoint... 
Iteration: 1563397374, states[0] = -31.588218, states[40]= 0.000422
Saving checkpoint... 
Iteration: 1580091833, states[0] = -95.299665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597357816, states[0] = -95.085651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614142330, states[0] = -92.969845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630907796, states[0] = -43.538710, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1648229388, states[0] = 17.613621, states[40]= 0.006869
Saving checkpoint... 
Iteration: 1664977623, states[0] = -95.294776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681721570, states[0] = -95.234175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699074347, states[0] = -95.143647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715941701, states[0] = -95.260592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732702568, states[0] = -95.203361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749975616, states[0] = -9.447946, states[40]= 0.002782
Saving checkpoint... 
Iteration: 1766760854, states[0] = 2.077360, states[40]= 0.005086
Saving checkpoint... 
Iteration: 1783579571, states[0] = -13.424202, states[40]= 0.001935
Saving checkpoint... 
Iteration: 1800866421, states[0] = -95.084466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817426646, states[0] = -95.072591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834082649, states[0] = -3.551186, states[40]= 0.003694
Saving checkpoint... 
Iteration: 1851432930, states[0] = -95.049806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868255983, states[0] = -94.945137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885063924, states[0] = 6.835125, states[40]= 0.004762
Saving checkpoint... 
Iteration: 1902364252, states[0] = -95.017592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919217726, states[0] = -94.881972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936000198, states[0] = -70.732276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953542210, states[0] = 15.176572, states[40]= 0.004986
Saving checkpoint... 
Iteration: 1970284759, states[0] = -94.965806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987086549, states[0] = -5.179711, states[40]= 0.003346
Saving checkpoint... 
Iteration: 2004338037, states[0] = -95.002109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021168314, states[0] = -93.586557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037952277, states[0] = -95.038231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055230927, states[0] = -94.901349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071946632, states[0] = -95.037136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088843077, states[0] = -95.004438, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.920788
 - CaMKt in component CaMK (millimolar): 0.007464
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.898266
 - nass in component intracellular_ions (millimolar): 6.898328
 - ki in component intracellular_ions (millimolar): 145.072206
 - kss in component intracellular_ions (millimolar): 145.072185
 - cansr in component intracellular_ions (millimolar): 1.339793
 - cajsr in component intracellular_ions (millimolar): 1.300973
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880329
 - hs in component INa (dimensionless): 0.880324
 - j in component INa (dimensionless): 0.880297
 - hsp in component INa (dimensionless): 0.726450
 - jp in component INa (dimensionless): 0.880278
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709714
 - hLp in component INaL (dimensionless): 0.450516
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.617538
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.691837
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932618
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001704
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335906
 - xs1 in component IKs (dimensionless): 0.248552
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:12:04 (22116): called boinc_finish(0)

</stderr_txt>
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