𝕏

Task 54511133

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_202_1
Workunit 25879640
Created 24 Jun 2024, 16:52:46 UTC
Sent 24 Jun 2024, 22:46:47 UTC
Report deadline 28 Jun 2024, 8:22:47 UTC
Received 25 Jun 2024, 15:37:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232784
Run time 1 hours 5 min 35 sec
CPU time 56 min 5 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.22 MB
Peak swap size 5.28 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_202.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_202_1_r1766081276_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Pueyo_APDR-conf_202_1_r1766081276_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.912554
     * GNaL_b in INaL: 0.007096
     * Gto_b in Ito: 0.075591
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033915
     * GKs_b in IKs: 0.001842
     * GK1_b in IK1: 0.146079
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 62.427958
     * GKb_b in IKb: 0.004013
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045122
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16864389, states[0] = -94.928701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34207690, states[0] = -94.750964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51045935, states[0] = 12.897724, states[40]= 0.005235
Saving checkpoint... 
Iteration: 67953939, states[0] = -94.926569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85336849, states[0] = -94.884532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102279111, states[0] = -94.839066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119095712, states[0] = -17.618793, states[40]= 0.001184
Saving checkpoint... 
Iteration: 136546244, states[0] = 12.908801, states[40]= 0.005225
Saving checkpoint... 
Iteration: 153367920, states[0] = -94.896066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170225571, states[0] = -94.765224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187596780, states[0] = -18.585994, states[40]= 0.001094
Saving checkpoint... 
Iteration: 204404398, states[0] = -94.908365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221259221, states[0] = -94.814352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238671812, states[0] = -94.503371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255603811, states[0] = -25.361256, states[40]= 0.000694
Saving checkpoint... 
Iteration: 272510383, states[0] = 24.151997, states[40]= 0.047874
Saving checkpoint... 
Iteration: 289911327, states[0] = -94.910146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306737726, states[0] = -94.784567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323599375, states[0] = -21.081096, states[40]= 0.000913
Saving checkpoint... 
Iteration: 340979997, states[0] = -94.923916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357821284, states[0] = -94.870817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374700760, states[0] = -94.717098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392093458, states[0] = -15.380395, states[40]= 0.001446
Saving checkpoint... 
Iteration: 408956432, states[0] = -94.920114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425800252, states[0] = -94.855420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443141348, states[0] = -65.372983, states[40]= 0.000002
Saving checkpoint... 
Iteration: 460053782, states[0] = 9.810429, states[40]= 0.005076
Saving checkpoint... 
Iteration: 476856424, states[0] = -94.890211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494328158, states[0] = -94.875085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511156648, states[0] = -87.437630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528001326, states[0] = 48.760671, states[40]= 0.052299
Saving checkpoint... 
Iteration: 545468500, states[0] = -94.922057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562276620, states[0] = -94.833691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579070088, states[0] = 2.159396, states[40]= 0.004613
Saving checkpoint... 
Iteration: 596349057, states[0] = -94.886589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613160955, states[0] = -91.800114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630055859, states[0] = 8.920017, states[40]= 0.005041
Saving checkpoint... 
Iteration: 647415371, states[0] = -94.910995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664218270, states[0] = -94.751507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681145033, states[0] = -70.108462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698395727, states[0] = -94.905261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715401500, states[0] = -94.907038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731959596, states[0] = -94.920464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748336268, states[0] = -94.879697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764953530, states[0] = -94.919363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781877436, states[0] = -94.898847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799057906, states[0] = 8.024976, states[40]= 0.005005
Saving checkpoint... 
Iteration: 815909222, states[0] = -94.909217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833045136, states[0] = 13.366012, states[40]= 0.005255
Saving checkpoint... 
Iteration: 850015599, states[0] = 22.817360, states[40]= 0.016960
Saving checkpoint... 
Iteration: 866795561, states[0] = -94.851248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883939238, states[0] = -94.916479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900926793, states[0] = -94.913691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917697395, states[0] = -94.709583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934810740, states[0] = -94.863156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951952010, states[0] = -94.918964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968784009, states[0] = -94.840769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986051797, states[0] = 10.646865, states[40]= 0.005110
Saving checkpoint... 
Iteration: 1002990089, states[0] = -94.924855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019807986, states[0] = -94.861067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037013836, states[0] = 23.203165, states[40]= 0.023039
Saving checkpoint... 
Iteration: 1054012406, states[0] = 23.542721, states[40]= 0.030644
Saving checkpoint... 
Iteration: 1070899508, states[0] = -94.906207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088182078, states[0] = -94.667949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105178787, states[0] = -94.647906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122048727, states[0] = 11.915653, states[40]= 0.005168
Saving checkpoint... 
Iteration: 1139365834, states[0] = -94.893967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156342076, states[0] = -94.882630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173315836, states[0] = -94.866625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190819028, states[0] = -94.868789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207781887, states[0] = -94.838567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224658229, states[0] = -89.363484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242014482, states[0] = 23.059868, states[40]= 0.020466
Saving checkpoint... 
Iteration: 1258924740, states[0] = -94.912973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275804762, states[0] = -94.858450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293176573, states[0] = -94.624543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310089665, states[0] = -11.817673, states[40]= 0.002026
Saving checkpoint... 
Iteration: 1326957705, states[0] = -94.919757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344336728, states[0] = -94.879578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361185957, states[0] = -94.681841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377998451, states[0] = -94.925647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395396673, states[0] = -94.905118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412206166, states[0] = -94.727596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429063026, states[0] = 5.692141, states[40]= 0.004889
Saving checkpoint... 
Iteration: 1446459197, states[0] = -94.919942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463310364, states[0] = -94.862546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480158049, states[0] = -89.161907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497561762, states[0] = 6.282438, states[40]= 0.004922
Saving checkpoint... 
Iteration: 1513694099, states[0] = -95.063077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530419464, states[0] = -62.448555, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1547690812, states[0] = -95.221947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564445276, states[0] = -95.187186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581215400, states[0] = -95.149635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598510730, states[0] = -53.091418, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1614985424, states[0] = -23.879126, states[40]= 0.000784
Saving checkpoint... 
Iteration: 1631757906, states[0] = 2.228450, states[40]= 0.005215
Saving checkpoint... 
Iteration: 1649095249, states[0] = -95.244730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665784954, states[0] = -95.095978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682574781, states[0] = -95.071345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699847339, states[0] = 8.503754, states[40]= 0.005839
Saving checkpoint... 
Iteration: 1716610785, states[0] = 24.484665, states[40]= 0.044540
Saving checkpoint... 
Iteration: 1733436506, states[0] = 14.136744, states[40]= 0.006538
Saving checkpoint... 
Iteration: 1750648074, states[0] = -94.808790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767370083, states[0] = -7.421821, states[40]= 0.003317
Saving checkpoint... 
Iteration: 1784235800, states[0] = -89.697290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801658076, states[0] = -93.055476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818403374, states[0] = -94.956048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835128042, states[0] = -51.932660, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1852396049, states[0] = -94.923711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869034966, states[0] = 17.114204, states[40]= 0.005770
Saving checkpoint... 
Iteration: 1885691125, states[0] = -94.702380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902962882, states[0] = -94.924768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919740204, states[0] = -94.790099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936534641, states[0] = 17.345339, states[40]= 0.005801
Saving checkpoint... 
Iteration: 1953826127, states[0] = -94.873925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970815354, states[0] = -94.866396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987502636, states[0] = 40.532403, states[40]= 0.124289
Saving checkpoint... 
Iteration: 2005077427, states[0] = -2.159849, states[40]= 0.004022
Saving checkpoint... 
Iteration: 2021775179, states[0] = -94.831366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038571710, states[0] = 1.273634, states[40]= 0.004517
Saving checkpoint... 
Iteration: 2055857743, states[0] = -94.889819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072619012, states[0] = -40.306875, states[40]= 0.000126
Saving checkpoint... 
Iteration: 2089343545, states[0] = -94.882780, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.801205
 - CaMKt in component CaMK (millimolar): 0.006996
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.821143
 - nass in component intracellular_ions (millimolar): 6.821204
 - ki in component intracellular_ions (millimolar): 145.154689
 - kss in component intracellular_ions (millimolar): 145.154669
 - cansr in component intracellular_ions (millimolar): 1.320350
 - cajsr in component intracellular_ions (millimolar): 1.282775
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003655
 - hf in component INa (dimensionless): 0.878243
 - hs in component INa (dimensionless): 0.878239
 - j in component INa (dimensionless): 0.878209
 - hsp in component INa (dimensionless): 0.722527
 - jp in component INa (dimensionless): 0.878189
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707850
 - hLp in component INaL (dimensionless): 0.450721
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.623529
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.698467
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935838
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001646
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334526
 - xs1 in component IKs (dimensionless): 0.237466
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997364
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:10:23 (3660): called boinc_finish(0)

</stderr_txt>
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