𝕏

Task 54488480

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-CLVPET-conf_182_1
Workunit 25868321
Created 24 Jun 2024, 16:42:08 UTC
Sent 24 Jun 2024, 20:11:48 UTC
Report deadline 27 Jun 2024, 23:04:36 UTC
Received 25 Jun 2024, 1:00:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 192169
Run time 1 hours 57 min 18 sec
CPU time 1 hours 57 min 18 sec
Validate state Valid
Credit 48.23
Device peak FLOPS 3.30 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.92 MB
Peak swap size 1.33 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-CLVPET-conf_182.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-CLVPET-conf_182_1_r1910843908_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-CLVPET-conf_182_1_r1910843908_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 106.238915
     * GNaL_b in INaL: 0.008702
     * Gto_b in Ito: 0.068682
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034011
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.169441
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 64.770277
     * GKb_b in IKb: 0.003852
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038192
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12396642, states[0] = -95.036487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25471306, states[0] = -95.036916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39750759, states[0] = -94.827398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54541163, states[0] = 21.843017, states[40]= 0.002918
Saving checkpoint... 
Iteration: 67664218, states[0] = -84.337927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81751535, states[0] = -94.827368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96524223, states[0] = 27.553993, states[40]= 0.002331
Saving checkpoint... 
Iteration: 110491810, states[0] = -95.035331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123289289, states[0] = -94.901777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136297456, states[0] = -94.914192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148920487, states[0] = -95.014670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161874311, states[0] = -94.990626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173701185, states[0] = -94.668817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186358499, states[0] = -94.979402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199903684, states[0] = -95.007089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214340608, states[0] = -94.964293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228986754, states[0] = -95.034190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243702619, states[0] = -94.674276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258358552, states[0] = -94.979226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273071029, states[0] = 9.044426, states[40]= 0.005026
Saving checkpoint... 
Iteration: 287275287, states[0] = -94.877423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301784737, states[0] = -94.893964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316446478, states[0] = -95.023539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330875824, states[0] = -94.991094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346327254, states[0] = -94.950672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361403057, states[0] = -95.006258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377781605, states[0] = -94.888395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393132757, states[0] = -42.628699, states[40]= 0.000284
Saving checkpoint... 
Iteration: 407775134, states[0] = -94.876730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423374726, states[0] = -94.990072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438047895, states[0] = 19.232081, states[40]= 0.003415
Saving checkpoint... 
Iteration: 453173325, states[0] = -93.558791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468055776, states[0] = 16.033597, states[40]= 0.004055
Saving checkpoint... 
Iteration: 482973835, states[0] = -95.030471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497589200, states[0] = -1.862089, states[40]= 0.004662
Saving checkpoint... 
Iteration: 512022290, states[0] = 28.056251, states[40]= 0.002598
Saving checkpoint... 
Iteration: 526991986, states[0] = -95.034241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541869422, states[0] = -94.986134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556853126, states[0] = -94.973946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571251545, states[0] = -94.826330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586065482, states[0] = 11.740954, states[40]= 0.004745
Saving checkpoint... 
Iteration: 601415485, states[0] = -95.011131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616497423, states[0] = -95.034972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631403916, states[0] = -95.005756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646562612, states[0] = 13.060167, states[40]= 0.004562
Saving checkpoint... 
Iteration: 661017449, states[0] = 29.091248, states[40]= 0.005417
Saving checkpoint... 
Iteration: 674398492, states[0] = -95.002917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689037518, states[0] = 23.180657, states[40]= 0.002652
Saving checkpoint... 
Iteration: 694508010, states[0] = 30.728380, states[40]= 0.091477
Saving checkpoint... 
Iteration: 708573165, states[0] = 7.947365, states[40]= 0.005103
Saving checkpoint... 
Iteration: 713948585, states[0] = -95.022843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717206595, states[0] = -94.687962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720204869, states[0] = -94.681370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723313884, states[0] = -94.934198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725827783, states[0] = -94.949936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740495523, states[0] = -95.034196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749559588, states[0] = 14.402882, states[40]= 0.004348
Saving checkpoint... 
Iteration: 761348629, states[0] = -94.969527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763290334, states[0] = -94.901438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767258055, states[0] = -94.840727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780007203, states[0] = 31.199777, states[40]= 0.119332
Saving checkpoint... 
Iteration: 791869082, states[0] = -94.985049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799385176, states[0] = -94.995223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813410060, states[0] = -95.008014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824847335, states[0] = -94.968207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825179960, states[0] = -94.457363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829327610, states[0] = -94.949401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842229057, states[0] = -94.764319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857762133, states[0] = -94.849323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873194596, states[0] = -94.639010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888958963, states[0] = -95.025277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888964843, states[0] = -95.026855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889367168, states[0] = -94.983389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889592223, states[0] = -4.181561, states[40]= 0.004218
Saving checkpoint... 
Iteration: 889893614, states[0] = -94.999634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889988196, states[0] = -95.032250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890135269, states[0] = -45.302109, states[40]= 0.000198
Saving checkpoint... 
Iteration: 891114898, states[0] = -25.303451, states[40]= 0.001298
Saving checkpoint... 
Iteration: 891697051, states[0] = -94.649530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892118336, states[0] = -28.531680, states[40]= 0.001176
Saving checkpoint... 
Iteration: 892230105, states[0] = -94.767331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902528236, states[0] = 26.367244, states[40]= 0.002226
Saving checkpoint... 
Iteration: 917078881, states[0] = 4.814936, states[40]= 0.005198
Saving checkpoint... 
Iteration: 931025536, states[0] = 27.180935, states[40]= 0.002249
Saving checkpoint... 
Iteration: 935477718, states[0] = -95.029836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935791327, states[0] = -94.902397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936044038, states[0] = 20.732862, states[40]= 0.003112
Saving checkpoint... 
Iteration: 936129371, states[0] = -39.156751, states[40]= 0.000442
Saving checkpoint... 
Iteration: 936238146, states[0] = -94.790473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947269408, states[0] = -94.863944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957265624, states[0] = -94.856294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957562082, states[0] = 13.299144, states[40]= 0.004526
Saving checkpoint... 
Iteration: 957904660, states[0] = -95.005003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958010326, states[0] = 30.061409, states[40]= 0.042793
Saving checkpoint... 
Iteration: 958308932, states[0] = -94.927202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958406308, states[0] = -95.005784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958822742, states[0] = -94.943695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959588246, states[0] = -1.169324, states[40]= 0.004770
Saving checkpoint... 
Iteration: 960252664, states[0] = -94.827663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968059750, states[0] = 14.332327, states[40]= 0.004360
Saving checkpoint... 
Iteration: 981794067, states[0] = -94.906429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995277738, states[0] = -94.879471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008907159, states[0] = -95.006012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022456530, states[0] = -95.024142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023078180, states[0] = 5.216418, states[40]= 0.005197
Saving checkpoint... 
Iteration: 1023607334, states[0] = -18.112324, states[40]= 0.001497
Saving checkpoint... 
Iteration: 1025962519, states[0] = -95.025777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040502960, states[0] = 41.205763, states[40]= 0.419731
Saving checkpoint... 
Iteration: 1055283379, states[0] = -94.889108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069333567, states[0] = -94.954670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082048810, states[0] = 18.871191, states[40]= 0.003490
Saving checkpoint... 
Iteration: 1095451808, states[0] = -95.022522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110876028, states[0] = -94.988570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123261208, states[0] = -94.846428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124849482, states[0] = -94.969007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125492376, states[0] = -95.032284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131764807, states[0] = -94.854010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141596193, states[0] = -7.535625, states[40]= 0.003423
Saving checkpoint... 
Iteration: 1151292718, states[0] = -94.903803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153578745, states[0] = 4.893536, states[40]= 0.005198
Saving checkpoint... 
Iteration: 1166961157, states[0] = -95.024932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179711127, states[0] = -94.703185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193154852, states[0] = -68.937542, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1205470969, states[0] = -95.027325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213296243, states[0] = -94.908877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221453533, states[0] = -95.022602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234240580, states[0] = -94.796115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234842927, states[0] = -94.962938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240794700, states[0] = -94.906494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243041821, states[0] = 21.578711, states[40]= 0.002947
Saving checkpoint... 
Iteration: 1256603158, states[0] = -14.064300, states[40]= 0.001983
Saving checkpoint... 
Iteration: 1270998819, states[0] = -95.033004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271230713, states[0] = -94.767859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271253128, states[0] = -94.827693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280509208, states[0] = 30.299614, states[40]= 0.061669
Saving checkpoint... 
Iteration: 1293997458, states[0] = -95.032676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306662500, states[0] = -81.410102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311351042, states[0] = -94.969671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323079930, states[0] = 4.204848, states[40]= 0.005193
Saving checkpoint... 
Iteration: 1337043037, states[0] = 21.116572, states[40]= 0.003037
Saving checkpoint... 
Iteration: 1343970256, states[0] = -95.026680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352401546, states[0] = -95.002144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364187242, states[0] = -94.596138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371349912, states[0] = -94.968528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385716781, states[0] = -94.722521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396695894, states[0] = -94.642871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410937771, states[0] = -95.016958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425707474, states[0] = -94.688833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437036015, states[0] = 23.726774, states[40]= 0.002560
Saving checkpoint... 
Iteration: 1449616746, states[0] = -27.036799, states[40]= 0.001247
Saving checkpoint... 
Iteration: 1462113476, states[0] = -23.964801, states[40]= 0.001319
Saving checkpoint... 
Iteration: 1474653133, states[0] = -66.542948, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1486908273, states[0] = -95.004904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497429488, states[0] = -95.013698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511236700, states[0] = -95.310641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524896307, states[0] = -59.841262, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1538247459, states[0] = -94.913806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551009501, states[0] = -94.902148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564414321, states[0] = -94.774742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577179163, states[0] = -84.985615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590085021, states[0] = -94.724335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603272419, states[0] = -94.715024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617177727, states[0] = -94.698736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630975007, states[0] = -94.634542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644975557, states[0] = -94.608769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658630942, states[0] = -94.616149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671956485, states[0] = -94.600997, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.471666
 - CaMKt in component CaMK (millimolar): 0.001117
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.447778
 - nass in component intracellular_ions (millimolar): 6.447864
 - ki in component intracellular_ions (millimolar): 145.454064
 - kss in component intracellular_ions (millimolar): 145.454052
 - cansr in component intracellular_ions (millimolar): 1.562597
 - cajsr in component intracellular_ions (millimolar): 1.562585
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003779
 - hf in component INa (dimensionless): 0.872332
 - hs in component INa (dimensionless): 0.872332
 - j in component INa (dimensionless): 0.872333
 - hsp in component INa (dimensionless): 0.711568
 - jp in component INa (dimensionless): 0.872334
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.717681
 - hLp in component INaL (dimensionless): 0.526154
 - a in component Ito (dimensionless): 0.000642
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.997794
 - ap in component Ito (dimensionless): 0.000327
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.999276
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998822
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002982
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001763
 - xs1 in component IKs (dimensionless): 0.023047
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997448
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:51:06 (18116): called boinc_finish(0)

</stderr_txt>
]]>


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