𝕏

Task 54480748

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974_0
Workunit 25864470
Created 24 Jun 2024, 16:38:25 UTC
Sent 24 Jun 2024, 19:49:28 UTC
Report deadline 27 Jun 2024, 19:49:28 UTC
Received 25 Jun 2024, 11:08:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223158
Run time 42 min 43 sec
CPU time 25 min 40 sec
Validate state Valid
Credit 42.66
Device peak FLOPS 5.90 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.69 MB
Peak swap size 389.84 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974_0_r2085581528_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974_0_r2085581528_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 110.399337
     * GNaL_b in INaL: 0.008915
     * Gto_b in Ito: 0.076802
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033752
     * GKs_b in IKs: 0.001753
     * GK1_b in IK1: 0.153219
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 62.855693
     * GKb_b in IKb: 0.003851
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038713
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 21111102, states[0] = -61.404242, states[40]= 0.000039
Saving checkpoint... 
Iteration: 38503033, states[0] = 29.104544, states[40]= 0.206049
Saving checkpoint... 
Iteration: 63165305, states[0] = 29.612694, states[40]= 0.423014
Saving checkpoint... 
Iteration: 84703390, states[0] = 15.458562, states[40]= 0.000011
Saving checkpoint... 
Iteration: 111171495, states[0] = 29.529094, states[40]= 0.007476
Saving checkpoint... 
Iteration: 132578751, states[0] = -38.298742, states[40]= 0.000205
Saving checkpoint... 
Iteration: 157897211, states[0] = -21.163072, states[40]= 0.000233
Saving checkpoint... 
Iteration: 177799916, states[0] = -84.820156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197973658, states[0] = -84.933795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220486800, states[0] = 28.986260, states[40]= 0.105178
Saving checkpoint... 
Iteration: 235179619, states[0] = 20.705862, states[40]= 0.000006
Saving checkpoint... 
Iteration: 253975722, states[0] = 34.907096, states[40]= 0.800136
Saving checkpoint... 
Iteration: 268628697, states[0] = -84.874672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285785775, states[0] = -84.764677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301986718, states[0] = 29.348938, states[40]= 0.005208
Saving checkpoint... 
Iteration: 315629465, states[0] = -84.937319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 340418807, states[0] = -76.405033, states[40]= 0.000004
Saving checkpoint... 
Iteration: 364359728, states[0] = 1.330592, states[40]= 0.000172
Saving checkpoint... 
Iteration: 383304973, states[0] = 29.228131, states[40]= 0.069200
Saving checkpoint... 
Iteration: 402853413, states[0] = 3.689902, states[40]= 0.000126
Saving checkpoint... 
Iteration: 423201465, states[0] = -17.429935, states[40]= 0.000239
Saving checkpoint... 
Iteration: 441665901, states[0] = 16.463798, states[40]= 0.000007
Saving checkpoint... 
Iteration: 458304156, states[0] = 29.395810, states[40]= 0.005736
Saving checkpoint... 
Iteration: 478357576, states[0] = -9.969868, states[40]= 0.000290
Saving checkpoint... 
Iteration: 501262349, states[0] = -84.720053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524145782, states[0] = 23.478650, states[40]= 0.000027
Saving checkpoint... 
Iteration: 544459506, states[0] = 29.642851, states[40]= 0.015603
Saving checkpoint... 
Iteration: 561912118, states[0] = -84.356064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582472138, states[0] = 24.083895, states[40]= 0.000041
Saving checkpoint... 
Iteration: 596882788, states[0] = -61.489337, states[40]= 0.000026
Saving checkpoint... 
Iteration: 613877816, states[0] = -56.957798, states[40]= 0.000042
Saving checkpoint... 
Iteration: 637180103, states[0] = -17.470650, states[40]= 0.000239
Saving checkpoint... 
Iteration: 656710302, states[0] = -61.724925, states[40]= 0.000025
Saving checkpoint... 
Iteration: 675361200, states[0] = -42.931689, states[40]= 0.000151
Saving checkpoint... 
Iteration: 696775995, states[0] = 29.588523, states[40]= 0.028465
Saving checkpoint... 
Iteration: 710478746, states[0] = 12.146813, states[40]= 0.000024
Saving checkpoint... 
Iteration: 730182279, states[0] = -33.799002, states[40]= 0.000240
Saving checkpoint... 
Iteration: 744294136, states[0] = 21.429746, states[40]= 0.000008
Saving checkpoint... 
Iteration: 763323950, states[0] = -3.149380, states[40]= 0.000254
Saving checkpoint... 
Iteration: 784809900, states[0] = 8.212204, states[40]= 0.000057
Saving checkpoint... 
Iteration: 806806453, states[0] = 9.186237, states[40]= 0.000047
Saving checkpoint... 
Iteration: 824937643, states[0] = 28.561365, states[40]= 0.001597
Saving checkpoint... 
Iteration: 838519252, states[0] = -53.194328, states[40]= 0.000062
Saving checkpoint... 
Iteration: 858239114, states[0] = -84.870427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876684952, states[0] = -57.046494, states[40]= 0.000042
Saving checkpoint... 
Iteration: 896401641, states[0] = -84.864124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 914937363, states[0] = 24.877717, states[40]= 0.000069
Saving checkpoint... 
Iteration: 929513145, states[0] = -57.236099, states[40]= 0.000041
Saving checkpoint... 
Iteration: 943232817, states[0] = -84.890773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962864764, states[0] = -83.010767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 981425523, states[0] = 27.277989, states[40]= 0.000444
Saving checkpoint... 
Iteration: 1000067324, states[0] = 30.753228, states[40]= 0.149810
Saving checkpoint... 
Iteration: 1021189762, states[0] = -81.792194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045249009, states[0] = 28.545583, states[40]= 0.001559
Saving checkpoint... 
Iteration: 1060772722, states[0] = 15.128661, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1087125481, states[0] = -3.829845, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1106134133, states[0] = -18.818584, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1126450056, states[0] = 1.481088, states[40]= 0.000169
Saving checkpoint... 
Iteration: 1141179880, states[0] = -82.844012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164147791, states[0] = -45.737887, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1183177363, states[0] = -83.408454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200843274, states[0] = -83.654658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218296107, states[0] = -28.192550, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1236423611, states[0] = 13.925490, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1252711206, states[0] = 32.883749, states[40]= 0.806661
Saving checkpoint... 
Iteration: 1272225147, states[0] = 28.887782, states[40]= 0.002381
Saving checkpoint... 
Iteration: 1289934586, states[0] = 0.603463, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1310302937, states[0] = -49.851496, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1331173143, states[0] = -84.524270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352260203, states[0] = 2.083958, states[40]= 0.000157
Saving checkpoint... 
Iteration: 1369161022, states[0] = -83.880643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1384634457, states[0] = -57.409772, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1403095911, states[0] = -6.411181, states[40]= 0.000287
Saving checkpoint... 
Iteration: 1415149130, states[0] = -80.889440, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1433496121, states[0] = -84.513464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454025358, states[0] = 30.610204, states[40]= 0.579868
Saving checkpoint... 
Iteration: 1474471680, states[0] = -75.726817, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1486207760, states[0] = 27.537448, states[40]= 0.000554
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.798220
 - CaMKt in component CaMK (millimolar): 0.221994
 - cass in component intracellular_ions (millimolar): 0.000174
 - nai in component intracellular_ions (millimolar): 7.562862
 - nass in component intracellular_ions (millimolar): 7.563221
 - ki in component intracellular_ions (millimolar): 143.526891
 - kss in component intracellular_ions (millimolar): 143.526855
 - cansr in component intracellular_ions (millimolar): 3.394696
 - cajsr in component intracellular_ions (millimolar): 1.966867
 - cai in component intracellular_ions (millimolar): 0.000163
 - m in component INa (dimensionless): 0.010006
 - hf in component INa (dimensionless): 0.582304
 - hs in component INa (dimensionless): 0.581184
 - j in component INa (dimensionless): 0.552782
 - hsp in component INa (dimensionless): 0.329852
 - jp in component INa (dimensionless): 0.512422
 - mL in component INaL (dimensionless): 0.000338
 - hL in component INaL (dimensionless): 0.184974
 - hLp in component INaL (dimensionless): 0.075517
 - a in component Ito (dimensionless): 0.001232
 - iF in component Ito (dimensionless): 0.999230
 - iS in component Ito (dimensionless): 0.133561
 - ap in component Ito (dimensionless): 0.000628
 - iFp in component Ito (dimensionless): 0.999231
 - iSp in component Ito (dimensionless): 0.149521
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.683379
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.930837
 - jca in component ICaL (dimensionless): 0.914436
 - ffp in component ICaL (dimensionless): 0.999066
 - fcafp in component ICaL (dimensionless): 0.999947
 - nca in component ICaL (dimensionless): 0.043671
 - xrf in component IKr (dimensionless): 0.096852
 - xrs in component IKr (dimensionless): 0.871685
 - xs1 in component IKs (dimensionless): 0.565414
 - xs2 in component IKs (dimensionless): 0.006676
 - xk1 in component IK1 (dimensionless): 0.996749
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
05:59:39 (55374): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974_0_r2085581528_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974_0_r2085581528_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 110.399337
     * GNaL_b in INaL: 0.008915
     * Gto_b in Ito: 0.076802
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033752
     * GKs_b in IKs: 0.001753
     * GK1_b in IK1: 0.153219
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 62.855693
     * GKb_b in IKb: 0.003851
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038713
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1486207760
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 27.537448 (After loading)
 - states[40]: 0.000554 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.798220
 - CaMKt in component CaMK (millimolar): 0.221994
 - cass in component intracellular_ions (millimolar): 0.000174
 - nai in component intracellular_ions (millimolar): 7.562862
 - nass in component intracellular_ions (millimolar): 7.563221
 - ki in component intracellular_ions (millimolar): 143.526891
 - kss in component intracellular_ions (millimolar): 143.526855
 - cansr in component intracellular_ions (millimolar): 3.394696
 - cajsr in component intracellular_ions (millimolar): 1.966867
 - cai in component intracellular_ions (millimolar): 0.000163
 - m in component INa (dimensionless): 0.010006
 - hf in component INa (dimensionless): 0.582304
 - hs in component INa (dimensionless): 0.581184
 - j in component INa (dimensionless): 0.552782
 - hsp in component INa (dimensionless): 0.329852
 - jp in component INa (dimensionless): 0.512422
 - mL in component INaL (dimensionless): 0.000338
 - hL in component INaL (dimensionless): 0.184974
 - hLp in component INaL (dimensionless): 0.075517
 - a in component Ito (dimensionless): 0.001232
 - iF in component Ito (dimensionless): 0.999230
 - iS in component Ito (dimensionless): 0.133561
 - ap in component Ito (dimensionless): 0.000628
 - iFp in component Ito (dimensionless): 0.999231
 - iSp in component Ito (dimensionless): 0.149521
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.683379
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.930837
 - jca in component ICaL (dimensionless): 0.914436
 - ffp in component ICaL (dimensionless): 0.999066
 - fcafp in component ICaL (dimensionless): 0.999947
 - nca in component ICaL (dimensionless): 0.043671
 - xrf in component IKr (dimensionless): 0.096852
 - xrs in component IKr (dimensionless): 0.871685
 - xs1 in component IKs (dimensionless): 0.565414
 - xs2 in component IKs (dimensionless): 0.006676
 - xk1 in component IK1 (dimensionless): 0.996749
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
06:03:24 (58296): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974_0_r2085581528_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Schmidt_333-conf_974_0_r2085581528_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 110.399337
     * GNaL_b in INaL: 0.008915
     * Gto_b in Ito: 0.076802
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033752
     * GKs_b in IKs: 0.001753
     * GK1_b in IK1: 0.153219
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 62.855693
     * GKb_b in IKb: 0.003851
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038713
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1486207760
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 27.537448 (After loading)
 - states[40]: 0.000554 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.798220
 - CaMKt in component CaMK (millimolar): 0.221994
 - cass in component intracellular_ions (millimolar): 0.000174
 - nai in component intracellular_ions (millimolar): 7.562862
 - nass in component intracellular_ions (millimolar): 7.563221
 - ki in component intracellular_ions (millimolar): 143.526891
 - kss in component intracellular_ions (millimolar): 143.526855
 - cansr in component intracellular_ions (millimolar): 3.394696
 - cajsr in component intracellular_ions (millimolar): 1.966867
 - cai in component intracellular_ions (millimolar): 0.000163
 - m in component INa (dimensionless): 0.010006
 - hf in component INa (dimensionless): 0.582304
 - hs in component INa (dimensionless): 0.581184
 - j in component INa (dimensionless): 0.552782
 - hsp in component INa (dimensionless): 0.329852
 - jp in component INa (dimensionless): 0.512422
 - mL in component INaL (dimensionless): 0.000338
 - hL in component INaL (dimensionless): 0.184974
 - hLp in component INaL (dimensionless): 0.075517
 - a in component Ito (dimensionless): 0.001232
 - iF in component Ito (dimensionless): 0.999230
 - iS in component Ito (dimensionless): 0.133561
 - ap in component Ito (dimensionless): 0.000628
 - iFp in component Ito (dimensionless): 0.999231
 - iSp in component Ito (dimensionless): 0.149521
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.683379
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.930837
 - jca in component ICaL (dimensionless): 0.914436
 - ffp in component ICaL (dimensionless): 0.999066
 - fcafp in component ICaL (dimensionless): 0.999947
 - nca in component ICaL (dimensionless): 0.043671
 - xrf in component IKr (dimensionless): 0.096852
 - xrs in component IKr (dimensionless): 0.871685
 - xs1 in component IKs (dimensionless): 0.565414
 - xs2 in component IKs (dimensionless): 0.006676
 - xk1 in component IK1 (dimensionless): 0.996749
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
06:07:13 (58410): called boinc_finish(0)

</stderr_txt>
]]>


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