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Task 54475231

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_6000-conf_669_1
Workunit 25861716
Created 24 Jun 2024, 16:35:50 UTC
Sent 24 Jun 2024, 19:31:32 UTC
Report deadline 27 Jun 2024, 19:31:32 UTC
Received 25 Jun 2024, 8:17:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216864
Run time 1 hours 5 min 4 sec
CPU time 39 min 4 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 5.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.52 MB
Peak swap size 391.88 GB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_6000-conf_669.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_6000-conf_669_1_r376401264_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_6000-conf_669_1_r376401264_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 113.841269
     * GNaL_b in INaL: 0.007977
     * Gto_b in Ito: 0.082963
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032093
     * GKs_b in IKs: 0.001885
     * GK1_b in IK1: 0.156456
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 65.508790
     * GKb_b in IKb: 0.003876
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054042
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22343171, states[0] = -94.064602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56181375, states[0] = -94.049484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87839387, states[0] = -94.122792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114765086, states[0] = -94.129709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136179844, states[0] = -94.126620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 167313017, states[0] = -94.106924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190354279, states[0] = -94.124568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213877666, states[0] = -94.139026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238921122, states[0] = -94.113004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266665453, states[0] = -94.106379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294807208, states[0] = -94.138843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320178420, states[0] = -94.109677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348711823, states[0] = -94.133305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376872425, states[0] = -94.113254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401642693, states[0] = -94.105810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423842696, states[0] = -94.138512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450279500, states[0] = -66.325640, states[40]= 0.000046
Saving checkpoint... 
Iteration: 478134709, states[0] = -94.131166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 499246842, states[0] = -94.127286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519824786, states[0] = -94.137744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541068631, states[0] = -94.132968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562757430, states[0] = -94.113982, states[40]= 0.000001
Saving checkpoint... 
Iteration: 585646950, states[0] = -94.122136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 609225815, states[0] = -30.005874, states[40]= 0.006311
Saving checkpoint... 
Iteration: 633055348, states[0] = 31.084715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655278918, states[0] = -94.125225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680155725, states[0] = -94.107586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705854214, states[0] = -94.136670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734462749, states[0] = -94.104632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755353967, states[0] = -94.105276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783134380, states[0] = 4.280461, states[40]= 0.000138
Saving checkpoint... 
Iteration: 804766520, states[0] = -94.134237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826170491, states[0] = -94.127655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 852050360, states[0] = 32.228487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878457492, states[0] = -94.103712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 903616098, states[0] = -94.112561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917405810, states[0] = -94.103811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934454553, states[0] = -94.118251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 952691481, states[0] = -94.112654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972269125, states[0] = -57.315636, states[40]= 0.000192
Saving checkpoint... 
Iteration: 983902667, states[0] = -94.100971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005456368, states[0] = -94.005033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036043614, states[0] = -94.130506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058607251, states[0] = -94.101637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069475966, states[0] = -94.116796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1086302746, states[0] = -92.954469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114954468, states[0] = -94.107161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136811392, states[0] = -94.100245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158525998, states[0] = -94.070418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185256136, states[0] = -47.578423, states[40]= 0.000833
Saving checkpoint... 
Iteration: 1210047855, states[0] = -94.129219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221206185, states[0] = -24.017831, states[40]= 0.006734
Saving checkpoint... 
Iteration: 1250212799, states[0] = -94.103229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282556325, states[0] = -94.113398, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1309109139, states[0] = -94.126534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1330879542, states[0] = -94.106835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361774473, states[0] = -94.098886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390326375, states[0] = -94.118886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411886926, states[0] = -94.106184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434708741, states[0] = -94.125833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459406383, states[0] = -94.116090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485286915, states[0] = -75.143792, states[40]= 0.000012
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.973279
 - CaMKt in component CaMK (millimolar): 0.001386
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.895047
 - nass in component intracellular_ions (millimolar): 7.895198
 - ki in component intracellular_ions (millimolar): 143.942368
 - kss in component intracellular_ions (millimolar): 143.942355
 - cansr in component intracellular_ions (millimolar): 1.772918
 - cajsr in component intracellular_ions (millimolar): 1.774063
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003974
 - hf in component INa (dimensionless): 0.862930
 - hs in component INa (dimensionless): 0.862931
 - j in component INa (dimensionless): 0.862931
 - hsp in component INa (dimensionless): 0.694473
 - jp in component INa (dimensionless): 0.862931
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.703996
 - hLp in component INaL (dimensionless): 0.509600
 - a in component Ito (dimensionless): 0.000664
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.999101
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.999667
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999249
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004317
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000688
 - xs1 in component IKs (dimensionless): 0.020085
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997571
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:45:19 (62999): called boinc_finish(0)

</stderr_txt>
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