𝕏

Task 54390687

Name HuVeMOp_20240623061122075563_ORdGradInc_k_23-Pueyo_APDR-conf_527_1
Workunit 25824339
Created 23 Jun 2024, 4:11:23 UTC
Sent 23 Jun 2024, 4:26:49 UTC
Report deadline 26 Jun 2024, 14:02:49 UTC
Received 23 Jun 2024, 6:59:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241028
Run time 2 hours 32 min 25 sec
CPU time 2 hours 30 min 34 sec
Validate state Valid
Credit 60.27
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.06 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623061122075563_ORdGradInc_k_23-Pueyo_APDR-conf_527.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623061122075563_ORdGradInc_k_23-Pueyo_APDR-conf_527_1_r1359466848_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623061122075563_ORdGradInc_k_23-Pueyo_APDR-conf_527_1_r1359466848_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 111.610290
     * GNaL_b in INaL: 0.020265
     * Gto_b in Ito: 0.084135
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030253
     * GKs_b in IKs: 0.001597
     * GK1_b in IK1: 0.186776
     * Gncx_b in INaCa_i: 0.000997
     * Pnak_b in INaK: 70.873303
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033914
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14818555, states[0] = -95.354947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29678056, states[0] = -51.717036, states[40]= 0.000035
Saving checkpoint... 
Iteration: 44588913, states[0] = 9.188185, states[40]= 0.004481
Saving checkpoint... 
Iteration: 59357090, states[0] = -95.331619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74120308, states[0] = -4.882869, states[40]= 0.003083
Saving checkpoint... 
Iteration: 89064611, states[0] = 17.989802, states[40]= 0.004545
Saving checkpoint... 
Iteration: 103899652, states[0] = -95.338603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118684585, states[0] = -55.795808, states[40]= 0.000018
Saving checkpoint... 
Iteration: 133406734, states[0] = -95.338852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148171670, states[0] = -41.269078, states[40]= 0.000167
Saving checkpoint... 
Iteration: 163041726, states[0] = 24.340836, states[40]= 0.004632
Saving checkpoint... 
Iteration: 177794484, states[0] = -95.279598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192283902, states[0] = -95.269928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206848531, states[0] = -95.315219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221464119, states[0] = -95.350540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236129082, states[0] = -9.893088, states[40]= 0.002090
Saving checkpoint... 
Iteration: 250689596, states[0] = -62.143904, states[40]= 0.000006
Saving checkpoint... 
Iteration: 265529144, states[0] = 26.876747, states[40]= 0.005800
Saving checkpoint... 
Iteration: 280468409, states[0] = -95.351157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295202355, states[0] = -84.908201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309961873, states[0] = -95.350025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324752654, states[0] = -95.235219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339562934, states[0] = 18.625312, states[40]= 0.004527
Saving checkpoint... 
Iteration: 354613270, states[0] = -0.674041, states[40]= 0.003759
Saving checkpoint... 
Iteration: 369529518, states[0] = 26.820253, states[40]= 0.005733
Saving checkpoint... 
Iteration: 384455350, states[0] = -95.348809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399418245, states[0] = -95.340606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414353311, states[0] = -95.317326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429358023, states[0] = -95.319530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444335636, states[0] = -95.308057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459229869, states[0] = -95.203531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473592252, states[0] = 8.550016, states[40]= 0.004412
Saving checkpoint... 
Iteration: 488457929, states[0] = -95.349230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503316802, states[0] = -95.296238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518271917, states[0] = -95.257491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533237938, states[0] = -95.215564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547859011, states[0] = -95.319922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562360414, states[0] = -95.320549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577350859, states[0] = -95.316054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592241704, states[0] = -95.220734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606753389, states[0] = -95.235997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621102085, states[0] = 4.514102, states[40]= 0.004236
Saving checkpoint... 
Iteration: 635480002, states[0] = -95.352777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649912147, states[0] = -95.338847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664384231, states[0] = -95.330052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678875738, states[0] = -95.326883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693281255, states[0] = -95.266919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707631264, states[0] = -11.350225, states[40]= 0.001841
Saving checkpoint... 
Iteration: 722132463, states[0] = -12.165470, states[40]= 0.001716
Saving checkpoint... 
Iteration: 736300428, states[0] = -95.283927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750437058, states[0] = -95.344935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764645653, states[0] = -21.284039, states[40]= 0.001237
Saving checkpoint... 
Iteration: 778986986, states[0] = -95.353708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793243572, states[0] = -95.223161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807173084, states[0] = -42.539604, states[40]= 0.000138
Saving checkpoint... 
Iteration: 821349845, states[0] = -95.315433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835656921, states[0] = -29.218220, states[40]= 0.000826
Saving checkpoint... 
Iteration: 849694326, states[0] = -69.283391, states[40]= 0.000002
Saving checkpoint... 
Iteration: 863765724, states[0] = -95.250536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877664804, states[0] = -35.239234, states[40]= 0.000392
Saving checkpoint... 
Iteration: 891547609, states[0] = 22.887717, states[40]= 0.004499
Saving checkpoint... 
Iteration: 905448726, states[0] = -95.347285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919670850, states[0] = -40.423017, states[40]= 0.000188
Saving checkpoint... 
Iteration: 933695280, states[0] = -70.891670, states[40]= 0.000002
Saving checkpoint... 
Iteration: 947675568, states[0] = -45.050286, states[40]= 0.000096
Saving checkpoint... 
Iteration: 961642498, states[0] = -19.110599, states[40]= 0.001230
Saving checkpoint... 
Iteration: 975484597, states[0] = -95.353275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989324945, states[0] = -95.301364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003458281, states[0] = -95.349039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017591626, states[0] = 8.794469, states[40]= 0.004420
Saving checkpoint... 
Iteration: 1031413112, states[0] = -95.338924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045340506, states[0] = -95.310471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059116708, states[0] = -2.457821, states[40]= 0.003498
Saving checkpoint... 
Iteration: 1073155098, states[0] = -27.895376, states[40]= 0.000939
Saving checkpoint... 
Iteration: 1086857608, states[0] = -95.319014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100635440, states[0] = -14.215414, states[40]= 0.001462
Saving checkpoint... 
Iteration: 1114282933, states[0] = -95.268332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128103221, states[0] = 4.020989, states[40]= 0.004206
Saving checkpoint... 
Iteration: 1142005450, states[0] = 30.402341, states[40]= 0.126185
Saving checkpoint... 
Iteration: 1155808398, states[0] = -95.289903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169621025, states[0] = -4.865440, states[40]= 0.003072
Saving checkpoint... 
Iteration: 1183441560, states[0] = -95.345688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197501011, states[0] = 49.979558, states[40]= 0.022405
Saving checkpoint... 
Iteration: 1211265217, states[0] = -95.249791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225044969, states[0] = 23.559254, states[40]= 0.004540
Saving checkpoint... 
Iteration: 1238867034, states[0] = -95.323091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252758098, states[0] = -95.241457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266906668, states[0] = -95.336993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281074468, states[0] = 14.987067, states[40]= 0.004542
Saving checkpoint... 
Iteration: 1295173739, states[0] = -43.184997, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1309337565, states[0] = -95.308719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323409607, states[0] = -95.337806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337266333, states[0] = -95.250986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351344889, states[0] = -95.312651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365667328, states[0] = -37.321157, states[40]= 0.000293
Saving checkpoint... 
Iteration: 1379660316, states[0] = -31.741713, states[40]= 0.000619
Saving checkpoint... 
Iteration: 1393851902, states[0] = -95.316161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408054586, states[0] = 21.021257, states[40]= 0.004484
Saving checkpoint... 
Iteration: 1422171480, states[0] = -41.006999, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1436285208, states[0] = -95.270329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450583726, states[0] = 11.764132, states[40]= 0.004496
Saving checkpoint... 
Iteration: 1464964414, states[0] = -95.349888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479273547, states[0] = -95.258737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493250223, states[0] = -95.231548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507772592, states[0] = -95.521371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521835935, states[0] = -95.496081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536258637, states[0] = -95.532905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550810498, states[0] = -15.431135, states[40]= 0.001532
Saving checkpoint... 
Iteration: 1565041964, states[0] = -95.526503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579586706, states[0] = 0.491298, states[40]= 0.004588
Saving checkpoint... 
Iteration: 1594053060, states[0] = -56.416590, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1608676083, states[0] = 5.741228, states[40]= 0.005117
Saving checkpoint... 
Iteration: 1623014242, states[0] = 26.902562, states[40]= 0.023318
Saving checkpoint... 
Iteration: 1636935375, states[0] = -36.330082, states[40]= 0.000334
Saving checkpoint... 
Iteration: 1651497960, states[0] = -95.584260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665922701, states[0] = 25.537064, states[40]= 0.009168
Saving checkpoint... 
Iteration: 1680443667, states[0] = -44.746291, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1694172732, states[0] = 7.238635, states[40]= 0.005212
Saving checkpoint... 
Iteration: 1708562481, states[0] = 11.661431, states[40]= 0.005389
Saving checkpoint... 
Iteration: 1722949892, states[0] = 16.673342, states[40]= 0.005538
Saving checkpoint... 
Iteration: 1737629963, states[0] = 23.647828, states[40]= 0.006886
Saving checkpoint... 
Iteration: 1752148392, states[0] = -50.474462, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1766289597, states[0] = -95.441945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780140177, states[0] = -95.531811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794238224, states[0] = -95.529367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808288055, states[0] = -95.313117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822833722, states[0] = -95.335488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837444683, states[0] = -95.365071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851967849, states[0] = -95.362482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866494663, states[0] = -95.362001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880587808, states[0] = 10.084969, states[40]= 0.004470
Saving checkpoint... 
Iteration: 1895013332, states[0] = 27.551746, states[40]= 0.025697
Saving checkpoint... 
Iteration: 1909440038, states[0] = -95.347076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923626802, states[0] = -8.489111, states[40]= 0.002357
Saving checkpoint... 
Iteration: 1938079733, states[0] = 13.159853, states[40]= 0.004523
Saving checkpoint... 
Iteration: 1952523687, states[0] = 27.514843, states[40]= 0.007344
Saving checkpoint... 
Iteration: 1966997810, states[0] = -95.354871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981588185, states[0] = 10.105718, states[40]= 0.004458
Saving checkpoint... 
Iteration: 1995741267, states[0] = -95.219543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009929794, states[0] = -95.342717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023875115, states[0] = -95.325992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037955001, states[0] = -95.347920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051997475, states[0] = -95.354445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065991666, states[0] = -95.353676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079984569, states[0] = -95.352688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093989374, states[0] = -95.353344, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.230590
 - CaMKt in component CaMK (millimolar): 0.007273
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.601719
 - nass in component intracellular_ions (millimolar): 6.601785
 - ki in component intracellular_ions (millimolar): 145.380234
 - kss in component intracellular_ions (millimolar): 145.380210
 - cansr in component intracellular_ions (millimolar): 1.298995
 - cajsr in component intracellular_ions (millimolar): 1.254878
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003500
 - hf in component INa (dimensionless): 0.885589
 - hs in component INa (dimensionless): 0.885584
 - j in component INa (dimensionless): 0.885555
 - hsp in component INa (dimensionless): 0.736446
 - jp in component INa (dimensionless): 0.885535
 - mL in component INaL (dimensionless): 0.000047
 - hL in component INaL (dimensionless): 0.704736
 - hLp in component INaL (dimensionless): 0.426345
 - a in component Ito (dimensionless): 0.000610
 - iF in component Ito (dimensionless): 0.999877
 - iS in component Ito (dimensionless): 0.571161
 - ap in component Ito (dimensionless): 0.000311
 - iFp in component Ito (dimensionless): 0.999877
 - iSp in component Ito (dimensionless): 0.638670
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.879278
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999575
 - jca in component ICaL (dimensionless): 0.999926
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001600
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.406538
 - xs1 in component IKs (dimensionless): 0.335798
 - xs2 in component IKs (dimensionless): 0.000085
 - xk1 in component IK1 (dimensionless): 0.997249
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:59:19 (441831): called boinc_finish(0)

</stderr_txt>
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