𝕏

Task 54389750

Name HuVeMOp_20240623053624180822_ORdGradInc_k_23-Pueyo_APDR-conf_475_0
Workunit 25823931
Created 23 Jun 2024, 3:36:31 UTC
Sent 23 Jun 2024, 4:19:05 UTC
Report deadline 26 Jun 2024, 13:55:05 UTC
Received 23 Jun 2024, 6:46:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 27 min 26 sec
CPU time 2 hours 25 min 23 sec
Validate state Valid
Credit 60.96
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623053624180822_ORdGradInc_k_23-Pueyo_APDR-conf_475.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623053624180822_ORdGradInc_k_23-Pueyo_APDR-conf_475_0_r1201346964_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623053624180822_ORdGradInc_k_23-Pueyo_APDR-conf_475_0_r1201346964_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.597654
     * GNaL_b in INaL: 0.009866
     * Gto_b in Ito: 0.069934
     * PCa_b in ICaL: 0.000077
     * GKr_b in IKr: 0.035280
     * GKs_b in IKs: 0.002200
     * GK1_b in IK1: 0.148821
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 83.899724
     * GKb_b in IKb: 0.004423
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.116951
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14723618, states[0] = -94.966001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29312839, states[0] = -94.963679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43915417, states[0] = -94.952775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58838315, states[0] = -94.910219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73721460, states[0] = -94.814175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88480843, states[0] = -94.913655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103162246, states[0] = -92.692056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117863565, states[0] = -94.886930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132499050, states[0] = -94.904537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147124880, states[0] = -44.012148, states[40]= 0.000054
Saving checkpoint... 
Iteration: 161754372, states[0] = -94.826920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176200129, states[0] = -94.765191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190752254, states[0] = -94.824277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205307506, states[0] = -94.861215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219860115, states[0] = -94.880922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234526662, states[0] = 20.371386, states[40]= 0.007920
Saving checkpoint... 
Iteration: 249047007, states[0] = 12.877671, states[40]= 0.005202
Saving checkpoint... 
Iteration: 263639242, states[0] = -61.042902, states[40]= 0.000003
Saving checkpoint... 
Iteration: 278142756, states[0] = -65.551929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292634221, states[0] = -54.851605, states[40]= 0.000009
Saving checkpoint... 
Iteration: 307144840, states[0] = -68.354038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321568704, states[0] = 3.684436, states[40]= 0.004512
Saving checkpoint... 
Iteration: 336576671, states[0] = -0.420060, states[40]= 0.004038
Saving checkpoint... 
Iteration: 351745284, states[0] = -94.817306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366524757, states[0] = 20.960630, states[40]= 0.008667
Saving checkpoint... 
Iteration: 381587932, states[0] = -8.093049, states[40]= 0.002610
Saving checkpoint... 
Iteration: 396445536, states[0] = -94.896582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411438361, states[0] = -94.895723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426441841, states[0] = -94.896141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441363083, states[0] = -94.881488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456595406, states[0] = -14.733551, states[40]= 0.001421
Saving checkpoint... 
Iteration: 471457460, states[0] = -94.897841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486485533, states[0] = -94.900266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501287161, states[0] = -94.849630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515999985, states[0] = -94.901236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530515794, states[0] = 23.383497, states[40]= 0.019307
Saving checkpoint... 
Iteration: 545038388, states[0] = 16.243220, states[40]= 0.005762
Saving checkpoint... 
Iteration: 559591282, states[0] = -10.948429, states[40]= 0.002042
Saving checkpoint... 
Iteration: 574106385, states[0] = -25.259953, states[40]= 0.000596
Saving checkpoint... 
Iteration: 588485155, states[0] = -94.900208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603042685, states[0] = 14.584597, states[40]= 0.005428
Saving checkpoint... 
Iteration: 617676081, states[0] = -94.686705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632486616, states[0] = -94.900301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647366856, states[0] = -94.882437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662319801, states[0] = -94.866441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677116037, states[0] = -34.663015, states[40]= 0.000212
Saving checkpoint... 
Iteration: 691825134, states[0] = -94.868669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706680158, states[0] = -94.723869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721627809, states[0] = -47.219875, states[40]= 0.000033
Saving checkpoint... 
Iteration: 736433807, states[0] = -94.895048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751145955, states[0] = -69.907465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765892703, states[0] = -94.888349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780746179, states[0] = -94.818026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795611569, states[0] = -30.275298, states[40]= 0.000368
Saving checkpoint... 
Iteration: 809992931, states[0] = -94.900691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824608399, states[0] = -27.202806, states[40]= 0.000505
Saving checkpoint... 
Iteration: 839226392, states[0] = -94.797309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853825999, states[0] = -94.868971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868507702, states[0] = 26.784397, states[40]= 0.074948
Saving checkpoint... 
Iteration: 883206967, states[0] = -94.773301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897867574, states[0] = -94.882550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912745735, states[0] = -94.817565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927310929, states[0] = -94.862346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941962292, states[0] = -94.898174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956510030, states[0] = 25.210409, states[40]= 0.050448
Saving checkpoint... 
Iteration: 971105010, states[0] = -23.935871, states[40]= 0.000660
Saving checkpoint... 
Iteration: 985729210, states[0] = -94.800454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000599520, states[0] = -18.656156, states[40]= 0.000988
Saving checkpoint... 
Iteration: 1015449511, states[0] = -94.896842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030945242, states[0] = -94.896358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046459779, states[0] = -94.897899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061865845, states[0] = -94.882046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077332200, states[0] = -94.871328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092371744, states[0] = -94.883555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107137010, states[0] = -58.263146, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1121954527, states[0] = -94.897346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136838228, states[0] = -94.873519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151557986, states[0] = 8.419248, states[40]= 0.004860
Saving checkpoint... 
Iteration: 1166200556, states[0] = -94.764682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181222890, states[0] = -94.793133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195978886, states[0] = -94.899545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211027295, states[0] = 20.171018, states[40]= 0.007713
Saving checkpoint... 
Iteration: 1225952595, states[0] = -94.897112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240951635, states[0] = -94.897005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256269579, states[0] = -94.837547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271623236, states[0] = -42.095515, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1285776848, states[0] = -94.842714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301027989, states[0] = 19.946746, states[40]= 0.007506
Saving checkpoint... 
Iteration: 1316186888, states[0] = -94.744460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330959941, states[0] = -94.897830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345723351, states[0] = -94.793626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360502102, states[0] = 46.041455, states[40]= 0.047571
Saving checkpoint... 
Iteration: 1375708620, states[0] = -94.775314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390836286, states[0] = -94.872747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406105900, states[0] = -24.792611, states[40]= 0.000618
Saving checkpoint... 
Iteration: 1420338585, states[0] = -94.873561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435310404, states[0] = -94.861943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450149706, states[0] = -75.490967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464783473, states[0] = -94.847037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479320571, states[0] = -94.866526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493922138, states[0] = -94.893206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508353193, states[0] = -95.145844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522465682, states[0] = -95.176138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536508777, states[0] = -95.139027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550656768, states[0] = -95.195174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565213206, states[0] = -54.274380, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1579769302, states[0] = -95.213474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594060665, states[0] = -95.081045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608162212, states[0] = -95.086871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622425639, states[0] = 19.185366, states[40]= 0.009291
Saving checkpoint... 
Iteration: 1636939468, states[0] = -92.758620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651210421, states[0] = 25.417093, states[40]= 0.046155
Saving checkpoint... 
Iteration: 1665269915, states[0] = -95.218944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679586355, states[0] = -95.132653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693988430, states[0] = -95.135910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708811613, states[0] = 24.793612, states[40]= 0.038099
Saving checkpoint... 
Iteration: 1723425822, states[0] = -95.183436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738044275, states[0] = -94.479728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752723453, states[0] = -69.185371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1767607711, states[0] = 27.508415, states[40]= 0.068624
Saving checkpoint... 
Iteration: 1782469242, states[0] = -95.103853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797478496, states[0] = -95.120071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812007456, states[0] = 26.758098, states[40]= 0.081010
Saving checkpoint... 
Iteration: 1827068866, states[0] = 2.900566, states[40]= 0.004477
Saving checkpoint... 
Iteration: 1841882628, states[0] = -94.908111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856582563, states[0] = -4.483836, states[40]= 0.003357
Saving checkpoint... 
Iteration: 1871854903, states[0] = -94.887055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886170487, states[0] = -94.517158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901011547, states[0] = 24.571748, states[40]= 0.038347
Saving checkpoint... 
Iteration: 1916178459, states[0] = -94.715008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931424221, states[0] = -94.894558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946344668, states[0] = -94.876204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961336204, states[0] = -94.872978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976467270, states[0] = -94.898581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991650245, states[0] = -76.356705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006398830, states[0] = -94.889248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021152394, states[0] = -79.837905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036005914, states[0] = 29.193218, states[40]= 0.092229
Saving checkpoint... 
Iteration: 2051329075, states[0] = -94.869834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066678872, states[0] = -94.715421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081048054, states[0] = 12.461699, states[40]= 0.005159
Saving checkpoint... 
Iteration: 2096087670, states[0] = -7.880307, states[40]= 0.002654
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.776618
 - CaMKt in component CaMK (millimolar): 0.005366
 - cass in component intracellular_ions (millimolar): 0.000068
 - nai in component intracellular_ions (millimolar): 6.314844
 - nass in component intracellular_ions (millimolar): 6.314895
 - ki in component intracellular_ions (millimolar): 145.690796
 - kss in component intracellular_ions (millimolar): 145.690776
 - cansr in component intracellular_ions (millimolar): 1.197813
 - cajsr in component intracellular_ions (millimolar): 1.162135
 - cai in component intracellular_ions (millimolar): 0.000069
 - m in component INa (dimensionless): 0.003665
 - hf in component INa (dimensionless): 0.877811
 - hs in component INa (dimensionless): 0.877808
 - j in component INa (dimensionless): 0.877792
 - hsp in component INa (dimensionless): 0.721729
 - jp in component INa (dimensionless): 0.877780
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707330
 - hLp in component INaL (dimensionless): 0.450195
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.621748
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.695942
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933665
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999879
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001189
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343315
 - xs1 in component IKs (dimensionless): 0.242978
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997370
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:46:35 (480515): called boinc_finish(0)

</stderr_txt>
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