Task 54365838
Name | HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1 |
Workunit | 25812926 |
Created | 22 Jun 2024, 23:17:25 UTC |
Sent | 23 Jun 2024, 0:47:24 UTC |
Report deadline | 26 Jun 2024, 10:23:24 UTC |
Received | 28 Jun 2024, 14:18:31 UTC |
Server state | Over |
Outcome | Success |
Client state | Done |
Exit status | 0 (0x00000000) |
Computer ID | 230611 |
Run time | 2 hours 48 min 7 sec |
CPU time | 1 hours 55 min 57 sec |
Validate state | Task was reported too late to validate |
Credit | 0.00 |
Device peak FLOPS | 3.63 GFLOPS |
Application version | Human ventricular cell models optimization v0.02 windows_x86_64 |
Peak working set size | 10.75 MB |
Peak swap size | 5.31 MB |
Peak disk usage | 0.33 MB |
Stderr output
<core_client_version>7.24.1</core_client_version> <![CDATA[ <stderr_txt> tates[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.948732 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 35195686 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.948732 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 35195686 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.948732 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 46744264, states[0] = -94.994439, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 46744264 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.994439 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 46744264 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.994439 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 64750693, states[0] = -94.995115, states[40]= 0.000000 Saving checkpoint... Iteration: 82554232, states[0] = 1.482274, states[40]= 0.005179 Saving checkpoint... Iteration: 100558913, states[0] = -2.138088, states[40]= 0.004553 Saving checkpoint... Iteration: 119440738, states[0] = -95.056575, states[40]= 0.000000 Saving checkpoint... Iteration: 136933607, states[0] = -95.055209, states[40]= 0.000000 Saving checkpoint... Iteration: 154696000, states[0] = -94.934161, states[40]= 0.000000 Saving checkpoint... Iteration: 172990952, states[0] = -95.060764, states[40]= 0.000000 Saving checkpoint... Iteration: 190890615, states[0] = -95.047594, states[40]= 0.000000 Saving checkpoint... Iteration: 210350339, states[0] = -95.037800, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 210350339 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.037800 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 210350339 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.037800 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 224551728, states[0] = 3.391323, states[40]= 0.005435 Saving checkpoint... Iteration: 237657095, states[0] = -94.871938, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 237657095 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.871938 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 237657095 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.871938 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 237657095 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.871938 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 237657095 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.871938 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 237657095 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.871938 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 237657095 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.871938 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 246266115, states[0] = -95.000343, states[40]= 0.000000 Saving checkpoint... Iteration: 255124783, states[0] = -93.287949, states[40]= 0.000000 Saving checkpoint... Iteration: 263939280, states[0] = -95.055278, states[40]= 0.000000 Saving checkpoint... Iteration: 272506755, states[0] = 30.984044, states[40]= 0.098536 Saving checkpoint... Iteration: 281928079, states[0] = -95.053755, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 281928079 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.053755 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 281928079 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.053755 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 292989218, states[0] = -95.060355, states[40]= 0.000000 Saving checkpoint... Iteration: 303893368, states[0] = -95.047955, states[40]= 0.000000 Saving checkpoint... Iteration: 314150801, states[0] = -94.860166, states[40]= 0.000000 Saving checkpoint... Iteration: 324691324, states[0] = -94.927345, states[40]= 0.000000 Saving checkpoint... Iteration: 335655507, states[0] = -94.868933, states[40]= 0.000000 Saving checkpoint... Iteration: 348451696, states[0] = -95.056715, states[40]= 0.000000 Saving checkpoint... Iteration: 366851985, states[0] = -95.038116, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 366851985 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.038116 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 377475369, states[0] = -95.059117, states[40]= 0.000000 Saving checkpoint... Iteration: 391217938, states[0] = -94.959794, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 391217938 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -94.959794 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 400289010, states[0] = -95.013568, states[40]= 0.000000 Saving checkpoint... Iteration: 409299328, states[0] = -95.018659, states[40]= 0.000000 Saving checkpoint... Iteration: 418833656, states[0] = -95.032388, states[40]= 0.000000 Saving checkpoint... Iteration: 427809936, states[0] = -95.023384, states[40]= 0.000000 Saving checkpoint... Iteration: 436219795, states[0] = -94.961724, states[40]= 0.000000 Saving checkpoint... Iteration: 445466865, states[0] = -95.058270, states[40]= 0.000000 Saving checkpoint... Iteration: 456766429, states[0] = -95.000404, states[40]= 0.000000 Saving checkpoint... Iteration: 474198926, states[0] = -94.937440, states[40]= 0.000000 Saving checkpoint... Iteration: 493456162, states[0] = -95.057130, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 493456162 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.057130 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 493456162 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.057130 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 504662859, states[0] = -94.882143, states[40]= 0.000000 Saving checkpoint... Iteration: 515620439, states[0] = -87.554603, states[40]= 0.000000 Saving checkpoint... Iteration: 525110190, states[0] = -65.807283, states[40]= 0.000002 Saving checkpoint... Iteration: 539613716, states[0] = -72.232347, states[40]= 0.000001 Saving checkpoint... Iteration: 551796595, states[0] = -95.017277, states[40]= 0.000000 Saving checkpoint... Iteration: 564186891, states[0] = -94.920910, states[40]= 0.000000 Saving checkpoint... Iteration: 576326908, states[0] = -95.029941, states[40]= 0.000000 Saving checkpoint... Iteration: 588492660, states[0] = -95.060452, states[40]= 0.000000 Saving checkpoint... Iteration: 600267935, states[0] = -95.001292, states[40]= 0.000000 Saving checkpoint... Iteration: 612275229, states[0] = -95.005784, states[40]= 0.000000 Saving checkpoint... Iteration: 623072975, states[0] = -17.255450, states[40]= 0.001367 Saving checkpoint... Iteration: 635263805, states[0] = -94.998576, states[40]= 0.000000 Saving checkpoint... Iteration: 647009188, states[0] = 28.086761, states[40]= 0.059082 Saving checkpoint... Iteration: 658731937, states[0] = -94.973505, states[40]= 0.000000 Saving checkpoint... Iteration: 670300307, states[0] = -95.018968, states[40]= 0.000000 Saving checkpoint... Iteration: 681350487, states[0] = -95.037507, states[40]= 0.000000 Saving checkpoint... Iteration: 693173139, states[0] = -94.899584, states[40]= 0.000000 Saving checkpoint... Iteration: 704728188, states[0] = -94.969959, states[40]= 0.000000 Saving checkpoint... Iteration: 716778182, states[0] = -95.007455, states[40]= 0.000000 Saving checkpoint... Iteration: 728372292, states[0] = -95.043185, states[40]= 0.000000 Saving checkpoint... Iteration: 738939267, states[0] = -95.054992, states[40]= 0.000000 Saving checkpoint... Iteration: 750178920, states[0] = -94.908804, states[40]= 0.000000 Saving checkpoint... Iteration: 761295266, states[0] = -95.016513, states[40]= 0.000000 Saving checkpoint... Iteration: 772727306, states[0] = -94.969072, states[40]= 0.000000 Saving checkpoint... Iteration: 784050248, states[0] = 4.395436, states[40]= 0.005560 Saving checkpoint... Iteration: 795310584, states[0] = -95.023448, states[40]= 0.000000 Saving checkpoint... Iteration: 806680795, states[0] = -94.911673, states[40]= 0.000000 Saving checkpoint... Iteration: 818406470, states[0] = -95.050060, states[40]= 0.000000 Saving checkpoint... Iteration: 830326769, states[0] = -95.029746, states[40]= 0.000000 Saving checkpoint... Iteration: 841668909, states[0] = -94.892442, states[40]= 0.000000 Saving checkpoint... Iteration: 853264693, states[0] = -94.999041, states[40]= 0.000000 Saving checkpoint... Iteration: 864740591, states[0] = -94.981014, states[40]= 0.000000 Saving checkpoint... Iteration: 876327295, states[0] = -95.029909, states[40]= 0.000000 Saving checkpoint... Iteration: 887849390, states[0] = -95.037071, states[40]= 0.000000 Saving checkpoint... Iteration: 899421717, states[0] = -95.052469, states[40]= 0.000000 Saving checkpoint... Iteration: 910890046, states[0] = -95.046949, states[40]= 0.000000 Saving checkpoint... Iteration: 922099586, states[0] = -50.643425, states[40]= 0.000023 Saving checkpoint... Iteration: 933324459, states[0] = -95.028844, states[40]= 0.000000 Saving checkpoint... Iteration: 944681797, states[0] = -94.913125, states[40]= 0.000000 Saving checkpoint... Iteration: 956129677, states[0] = -94.634692, states[40]= 0.000000 Saving checkpoint... Iteration: 967644354, states[0] = -94.847342, states[40]= 0.000000 Saving checkpoint... Iteration: 979189424, states[0] = -94.924303, states[40]= 0.000000 Saving checkpoint... Iteration: 990813849, states[0] = -95.024691, states[40]= 0.000000 Saving checkpoint... Iteration: 1002007920, states[0] = 29.411528, states[40]= 0.077560 Saving checkpoint... Iteration: 1013703546, states[0] = -94.942954, states[40]= 0.000000 Saving checkpoint... Iteration: 1025385866, states[0] = -95.046029, states[40]= 0.000000 Saving checkpoint... Iteration: 1036841265, states[0] = -95.034521, states[40]= 0.000000 Saving checkpoint... Iteration: 1048525373, states[0] = 18.817555, states[40]= 0.008725 Saving checkpoint... Iteration: 1059933719, states[0] = -95.054083, states[40]= 0.000000 Saving checkpoint... Iteration: 1070573063, states[0] = -17.364770, states[40]= 0.001352 Saving checkpoint... Iteration: 1082267526, states[0] = -95.000755, states[40]= 0.000000 Saving checkpoint... Iteration: 1093827236, states[0] = -95.029764, states[40]= 0.000000 Saving checkpoint... Iteration: 1105683397, states[0] = -94.915448, states[40]= 0.000000 Saving checkpoint... Iteration: 1117578546, states[0] = -24.231955, states[40]= 0.000720 Saving checkpoint... Iteration: 1128328982, states[0] = -95.030367, states[40]= 0.000000 Saving checkpoint... Iteration: 1139838123, states[0] = -95.033458, states[40]= 0.000000 Saving checkpoint... Iteration: 1151400591, states[0] = -95.048828, states[40]= 0.000000 Saving checkpoint... Iteration: 1163229180, states[0] = -94.970642, states[40]= 0.000000 Saving checkpoint... Iteration: 1174537854, states[0] = 12.017735, states[40]= 0.006566 Saving checkpoint... Iteration: 1186327309, states[0] = -95.029738, states[40]= 0.000000 Saving checkpoint... Iteration: 1197582440, states[0] = -29.097702, states[40]= 0.000456 Saving checkpoint... Iteration: 1209041592, states[0] = 9.828950, states[40]= 0.006227 Saving checkpoint... Iteration: 1220989604, states[0] = -95.059852, states[40]= 0.000000 Saving checkpoint... Iteration: 1232903286, states[0] = -95.049266, states[40]= 0.000000 Saving checkpoint... Iteration: 1244897845, states[0] = -95.048268, states[40]= 0.000000 Saving checkpoint... Iteration: 1252961039, states[0] = -95.057219, states[40]= 0.000000 Saving checkpoint... Iteration: 1263494418, states[0] = -95.060203, states[40]= 0.000000 Saving checkpoint... Iteration: 1273625437, states[0] = -93.649237, states[40]= 0.000000 Saving checkpoint... Iteration: 1284808761, states[0] = -95.022394, states[40]= 0.000000 Saving checkpoint... Iteration: 1296607867, states[0] = -62.123128, states[40]= 0.000004 Saving checkpoint... Iteration: 1308963281, states[0] = -95.057418, states[40]= 0.000000 Saving checkpoint... Iteration: 1320885749, states[0] = -95.045836, states[40]= 0.000000 Saving checkpoint... Iteration: 1332362119, states[0] = -95.040323, states[40]= 0.000000 Saving checkpoint... Iteration: 1342902363, states[0] = -95.049039, states[40]= 0.000000 Saving checkpoint... Iteration: 1359801854, states[0] = -95.019289, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1359801854 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.019289 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 1376526209, states[0] = 18.384816, states[40]= 0.008474 Saving checkpoint... Iteration: 1388042881, states[0] = 9.055489, states[40]= 0.006122 Saving checkpoint... Iteration: 1401336827, states[0] = -95.032886, states[40]= 0.000000 Saving checkpoint... Iteration: 1420579777, states[0] = -25.772490, states[40]= 0.000627 Saving checkpoint... Iteration: 1441493285, states[0] = -95.060015, states[40]= 0.000000 Saving checkpoint... Iteration: 1459400816, states[0] = -95.048694, states[40]= 0.000000 Saving checkpoint... Iteration: 1478238593, states[0] = -94.978962, states[40]= 0.000000 Saving checkpoint... Iteration: 1497412461, states[0] = -95.050679, states[40]= 0.000000 Saving checkpoint... Iteration: 1515319195, states[0] = 21.682429, states[40]= 0.013975 Saving checkpoint... Iteration: 1532844992, states[0] = -95.079577, states[40]= 0.000000 Saving checkpoint... Iteration: 1550431653, states[0] = 13.843238, states[40]= 0.008158 Saving checkpoint... Iteration: 1568012714, states[0] = -95.186959, states[40]= 0.000000 Saving checkpoint... Iteration: 1577586533, states[0] = -95.157570, states[40]= 0.000000 Saving checkpoint... Iteration: 1586850429, states[0] = -95.099521, states[40]= 0.000000 Saving checkpoint... Iteration: 1597827434, states[0] = 16.392311, states[40]= 0.009129 Saving checkpoint... Iteration: 1608443930, states[0] = -95.087516, states[40]= 0.000000 Saving checkpoint... Iteration: 1625091796, states[0] = -95.243417, states[40]= 0.000000 Saving checkpoint... Iteration: 1641164663, states[0] = -95.126983, states[40]= 0.000000 =============================================================== --- DENIS Myocyte Simulator --- Version 0.22 - Beta --------------------------------------------------------------- https://denis.usj.es Universidad San Jorge =============================================================== Boinc file names: - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325.xml - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_0 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_325_1_r102771698_1 - CHECKPOINT_FILE: denis_checkpoint - CHECKPOINT_FILE_2: denis_checkpoint_2 Configuration: - Model name: ORd_SS_biphasic - Solver: FE - Simulation time: 4200000.000000 - dt: 0.002000 - Constants to change: 21 * GNa in INa: 90.415220 * GNaL_b in INaL: 0.002600 * Gto_b in Ito: 0.043302 * PCa_b in ICaL: 0.000082 * GKr_b in IKr: 0.037224 * GKs_b in IKs: 0.002220 * GK1_b in IK1: 0.229199 * Gncx_b in INaCa_i: 0.000921 * Pnak_b in INaK: 70.836766 * GKb_b in IKb: 0.004232 * PNab in INab: 0.000000 * PCab in ICab: 0.000000 * GpCa in IpCa: 0.016461 * celltype in environment: 0.000000 * nCL_1 in membrane: 1000.000000 * CL_1 in membrane: 600.000000 * nCL_2 in membrane: 600.000000 * CL_2 in membrane: 1000.000000 * cao in extracellular: 1.000000 * ko in extracellular: 4.000000 * nao in extracellular: 144.000000 Starting output configuration... No Output to save. Loading checkpoint... Loading iteration number... - Iteration number: 1641164663 Loading states... - states[0]: -87.000000 (Before loading) - states[40]: 0.000000 (Before loading) - states[0]: -95.126983 (After loading) - states[40]: 0.000000 (After loading) Loading output... Loading postprocessing... Loading startTime... Loading startAP... Loading num AP... Loading resultsTime... Loading resultsAPD90... Loading resultsAPD75... Loading resultsAPD50... Loading resultsAPD25... Loading resultsAPD10... Loading resultsTriangulation... Loading resultsMaxV... Loading resultsMinV... Loading resultsMaxDiffV... Loading resultsMinDiffV... Copy resultsTime... Copy resultsAPD90... Copy resultsAPD75... Copy resultsAPD50... Copy resultsAPD25... Copy resultsAPD10... Copy resultsTriangulation... Copy resultsMaxV... Copy resultsMinV... Copy resultsMaxDiffV... Copy resultsMinDiffV... Loading last results... Postprocessing loaded. Simulation loaded. Checkpoint loaded. Saving checkpoint... Iteration: 1655212719, states[0] = -93.932070, states[40]= 0.000000 Saving checkpoint... Iteration: 1668678662, states[0] = -37.257898, states[40]= 0.000181 Saving checkpoint... Iteration: 1681872287, states[0] = -28.424969, states[40]= 0.000511 Saving checkpoint... Iteration: 1698774531, states[0] = -95.143050, states[40]= 0.000000 Saving checkpoint... Iteration: 1716707553, states[0] = -87.456195, states[40]= 0.000000 Saving checkpoint... Iteration: 1736856429, states[0] = -95.112745, states[40]= 0.000000 Saving checkpoint... Iteration: 1755676719, states[0] = -34.585425, states[40]= 0.000255 Saving checkpoint... Iteration: 1774006531, states[0] = -85.082177, states[40]= 0.000000 Saving checkpoint... Iteration: 1794305409, states[0] = 34.033394, states[40]= 0.109315 Saving checkpoint... Iteration: 1813681887, states[0] = -94.930079, states[40]= 0.000000 Saving checkpoint... Iteration: 1833901443, states[0] = -95.059688, states[40]= 0.000000 Saving checkpoint... Iteration: 1855142269, states[0] = -94.848265, states[40]= 0.000000 Saving checkpoint... Iteration: 1873556845, states[0] = -0.520587, states[40]= 0.004857 Saving checkpoint... Iteration: 1893128554, states[0] = -94.539705, states[40]= 0.000000 Saving checkpoint... Iteration: 1906463949, states[0] = -95.058366, states[40]= 0.000000 Saving checkpoint... Iteration: 1926651609, states[0] = -94.861401, states[40]= 0.000000 Saving checkpoint... Iteration: 1945616256, states[0] = -77.825279, states[40]= 0.000000 Saving checkpoint... Iteration: 1966401463, states[0] = -95.048690, states[40]= 0.000000 Saving checkpoint... Iteration: 1985695931, states[0] = -94.932732, states[40]= 0.000000 Saving checkpoint... Iteration: 2007327932, states[0] = -95.029514, states[40]= 0.000000 Saving checkpoint... Iteration: 2028077539, states[0] = -22.972680, states[40]= 0.000804 Saving checkpoint... Iteration: 2048275740, states[0] = -95.005246, states[40]= 0.000000 Saving checkpoint... Iteration: 2069640640, states[0] = -94.838480, states[40]= 0.000000 Saving checkpoint... Iteration: 2089290757, states[0] = -95.013469, states[40]= 0.000000 Total time: 4200000.000000 State Variables: - v in component membrane (millivolt): -94.935981 - CaMKt in component CaMK (millimolar): 0.006364 - cass in component intracellular_ions (millimolar): 0.000075 - nai in component intracellular_ions (millimolar): 6.715922 - nass in component intracellular_ions (millimolar): 6.715979 - ki in component intracellular_ions (millimolar): 145.260034 - kss in component intracellular_ions (millimolar): 145.260017 - cansr in component intracellular_ions (millimolar): 1.322152 - cajsr in component intracellular_ions (millimolar): 1.287931 - cai in component intracellular_ions (millimolar): 0.000076 - m in component INa (dimensionless): 0.003606 - hf in component INa (dimensionless): 0.880592 - hs in component INa (dimensionless): 0.880589 - j in component INa (dimensionless): 0.880571 - hsp in component INa (dimensionless): 0.726955 - jp in component INa (dimensionless): 0.880559 - mL in component INaL (dimensionless): 0.000049 - hL in component INaL (dimensionless): 0.718393 - hLp in component INaL (dimensionless): 0.478681 - a in component Ito (dimensionless): 0.000622 - iF in component Ito (dimensionless): 0.999870 - iS in component Ito (dimensionless): 0.657046 - ap in component Ito (dimensionless): 0.000317 - iFp in component Ito (dimensionless): 0.999870 - iSp in component Ito (dimensionless): 0.739610 - d in component ICaL (dimensionless): 0.000000 - ff in component ICaL (dimensionless): 1.000000 - fs in component ICaL (dimensionless): 0.951350 - fcaf in component ICaL (dimensionless): 1.000000 - fcas in component ICaL (dimensionless): 0.999937 - jca in component ICaL (dimensionless): 0.999990 - ffp in component ICaL (dimensionless): 1.000000 - fcafp in component ICaL (dimensionless): 1.000000 - nca in component ICaL (dimensionless): 0.001710 - xrf in component IKr (dimensionless): 0.000003 - xrs in component IKr (dimensionless): 0.308604 - xs1 in component IKs (dimensionless): 0.189151 - xs2 in component IKs (dimensionless): 0.000087 - xk1 in component IK1 (dimensionless): 0.997328 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000 10:18:19 (22288): called boinc_finish(0) </stderr_txt> ]]>