𝕏

Task 54365721

Name HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_418_0
Workunit 25812868
Created 22 Jun 2024, 23:17:19 UTC
Sent 23 Jun 2024, 0:47:37 UTC
Report deadline 26 Jun 2024, 10:23:37 UTC
Received 25 Jun 2024, 15:02:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240430
Run time 3 hours 9 min 51 sec
CPU time 3 hours 8 min 42 sec
Validate state Valid
Credit 57.07
Device peak FLOPS 3.34 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.34 MB
Peak swap size 6.22 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_418.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_418_0_r1627367219_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_418_0_r1627367219_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.413097
     * GNaL_b in INaL: 0.008995
     * Gto_b in Ito: 0.053040
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.037686
     * GKs_b in IKs: 0.002097
     * GK1_b in IK1: 0.104877
     * Gncx_b in INaCa_i: 0.000999
     * Pnak_b in INaK: 60.203007
     * GKb_b in IKb: 0.004348
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.125229
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12055898, states[0] = 7.234221, states[40]= 0.005110
Saving checkpoint... 
Iteration: 24196910, states[0] = -94.989892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36322310, states[0] = -95.104895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48398841, states[0] = -95.116713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60471277, states[0] = -95.117424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72452111, states[0] = -95.106676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84589743, states[0] = -14.674023, states[40]= 0.001492
Saving checkpoint... 
Iteration: 96720644, states[0] = -94.961519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108850125, states[0] = -95.067985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120962636, states[0] = -95.092213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133080606, states[0] = -5.731870, states[40]= 0.003219
Saving checkpoint... 
Iteration: 145162308, states[0] = -93.896213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157226653, states[0] = -94.961281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169371367, states[0] = -95.068980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181491584, states[0] = -95.090522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193560749, states[0] = 6.241444, states[40]= 0.004915
Saving checkpoint... 
Iteration: 205701104, states[0] = -94.918110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217829414, states[0] = -95.051021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229959024, states[0] = -95.086097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242105743, states[0] = -31.436944, states[40]= 0.000307
Saving checkpoint... 
Iteration: 254236203, states[0] = -94.972362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266326532, states[0] = -95.049239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278436224, states[0] = -95.082521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290569621, states[0] = 1.672405, states[40]= 0.004468
Saving checkpoint... 
Iteration: 302670202, states[0] = -94.673080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314803686, states[0] = -95.036023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326923428, states[0] = -95.080200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338998138, states[0] = -95.089879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351100248, states[0] = -25.428051, states[40]= 0.000566
Saving checkpoint... 
Iteration: 363239603, states[0] = -94.976585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374170085, states[0] = -94.668019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386149663, states[0] = -85.766587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398286384, states[0] = -95.023701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410415389, states[0] = -95.078589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422548509, states[0] = 11.913533, states[40]= 0.005393
Saving checkpoint... 
Iteration: 434677290, states[0] = -94.832475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446797245, states[0] = -95.031652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458910002, states[0] = -95.077450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471045101, states[0] = 13.438250, states[40]= 0.005577
Saving checkpoint... 
Iteration: 483182655, states[0] = -94.870845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495284581, states[0] = -95.022260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507430529, states[0] = -95.081413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519537789, states[0] = 16.652069, states[40]= 0.006195
Saving checkpoint... 
Iteration: 531669318, states[0] = -94.632580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543744911, states[0] = -94.983123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555882207, states[0] = -95.070518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568018139, states[0] = 24.363081, states[40]= 0.015187
Saving checkpoint... 
Iteration: 580118864, states[0] = -46.602207, states[40]= 0.000035
Saving checkpoint... 
Iteration: 592252790, states[0] = -94.992248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604254156, states[0] = -94.993754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616373106, states[0] = -95.067779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628504332, states[0] = 36.165068, states[40]= 0.079349
Saving checkpoint... 
Iteration: 640656826, states[0] = -91.959294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652800396, states[0] = -95.033745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664936734, states[0] = -95.082420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677062710, states[0] = 5.293373, states[40]= 0.004836
Saving checkpoint... 
Iteration: 689185600, states[0] = -94.882443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701328529, states[0] = -95.050012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713425968, states[0] = -95.080552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725566385, states[0] = 3.424585, states[40]= 0.004662
Saving checkpoint... 
Iteration: 737676051, states[0] = -94.817499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749809427, states[0] = -95.039482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761933905, states[0] = -95.081929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774071521, states[0] = 0.583587, states[40]= 0.004329
Saving checkpoint... 
Iteration: 786205768, states[0] = -94.925604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798346940, states[0] = -95.058320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810491731, states[0] = -95.089188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822569914, states[0] = 1.508761, states[40]= 0.004448
Saving checkpoint... 
Iteration: 834681369, states[0] = -94.864180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846823440, states[0] = -95.047378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858919192, states[0] = -95.079238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871040214, states[0] = 15.597878, states[40]= 0.005946
Saving checkpoint... 
Iteration: 883088395, states[0] = -12.773957, states[40]= 0.001793
Saving checkpoint... 
Iteration: 895190749, states[0] = -94.896587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907329934, states[0] = -95.050657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919392076, states[0] = -95.073112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931451710, states[0] = -95.084617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943573355, states[0] = -0.522815, states[40]= 0.004171
Saving checkpoint... 
Iteration: 955701977, states[0] = -94.918873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967774156, states[0] = -95.013413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979902867, states[0] = -95.075735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992005727, states[0] = 32.602890, states[40]= 0.080850
Saving checkpoint... 
Iteration: 1004068256, states[0] = 2.426601, states[40]= 0.004556
Saving checkpoint... 
Iteration: 1016184566, states[0] = -94.878703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028317389, states[0] = -95.044058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040292161, states[0] = -95.027895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052369579, states[0] = -95.066548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064508293, states[0] = 29.132583, states[40]= 0.061936
Saving checkpoint... 
Iteration: 1076635038, states[0] = -66.912694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088756745, states[0] = -94.996437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100879140, states[0] = -95.069498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112997123, states[0] = -95.089590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125117539, states[0] = -44.969534, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1137252209, states[0] = -94.991469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149375982, states[0] = -95.068540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161469188, states[0] = -95.086788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173481238, states[0] = -95.088094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185585710, states[0] = -10.123423, states[40]= 0.002292
Saving checkpoint... 
Iteration: 1197705511, states[0] = -94.925059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209820446, states[0] = -95.045696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221935653, states[0] = -95.082110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234069970, states[0] = 1.477184, states[40]= 0.004445
Saving checkpoint... 
Iteration: 1246177038, states[0] = -94.829504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258304213, states[0] = -95.036102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270226427, states[0] = -94.958392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282350970, states[0] = -95.059825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294439629, states[0] = -95.082735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306557962, states[0] = 7.581610, states[40]= 0.005020
Saving checkpoint... 
Iteration: 1318684288, states[0] = -94.877576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330805575, states[0] = -95.036954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342941175, states[0] = -95.082966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355042215, states[0] = 14.718416, states[40]= 0.005776
Saving checkpoint... 
Iteration: 1367154440, states[0] = -90.425416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379191035, states[0] = -94.897133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391312057, states[0] = -95.040906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403434525, states[0] = -95.081880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415568537, states[0] = 2.273458, states[40]= 0.004539
Saving checkpoint... 
Iteration: 1427681663, states[0] = -94.865644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439804607, states[0] = -95.036311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451909220, states[0] = -95.077043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464050431, states[0] = 11.047232, states[40]= 0.005306
Saving checkpoint... 
Iteration: 1476189141, states[0] = -94.892534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488290261, states[0] = -95.026386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500410834, states[0] = -53.475809, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1512531241, states[0] = -95.411933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524609085, states[0] = 28.997220, states[40]= 0.051716
Saving checkpoint... 
Iteration: 1536712754, states[0] = -61.412246, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1548829397, states[0] = -95.471469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560940078, states[0] = 12.449053, states[40]= 0.006563
Saving checkpoint... 
Iteration: 1573053531, states[0] = -95.272184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585158466, states[0] = -95.526420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597237039, states[0] = 13.991425, states[40]= 0.006954
Saving checkpoint... 
Iteration: 1609338717, states[0] = -93.710193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621455044, states[0] = -95.531081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633504903, states[0] = 35.081984, states[40]= 0.070669
Saving checkpoint... 
Iteration: 1645615585, states[0] = -67.307279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1657700181, states[0] = -95.461164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669809975, states[0] = 27.966152, states[40]= 0.046677
Saving checkpoint... 
Iteration: 1681922573, states[0] = -77.278792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694031294, states[0] = -95.508562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705994938, states[0] = -95.452620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718092785, states[0] = -95.564400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730204954, states[0] = -52.669555, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1742299504, states[0] = -95.461169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754414127, states[0] = 25.446448, states[40]= 0.025797
Saving checkpoint... 
Iteration: 1766496555, states[0] = -41.268389, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1778596727, states[0] = -95.456196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790715635, states[0] = 24.687425, states[40]= 0.021319
Saving checkpoint... 
Iteration: 1802827876, states[0] = -95.174499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814952472, states[0] = -95.179551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826991714, states[0] = -95.158301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839102560, states[0] = -29.747476, states[40]= 0.000373
Saving checkpoint... 
Iteration: 1851193211, states[0] = -94.938082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863306426, states[0] = -95.063248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875407375, states[0] = -95.095207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887525001, states[0] = 21.776850, states[40]= 0.009201
Saving checkpoint... 
Iteration: 1899635525, states[0] = -67.995020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1911732665, states[0] = -94.974156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923818280, states[0] = -95.049449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935840324, states[0] = -95.058939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947949644, states[0] = -95.086765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960060418, states[0] = 6.387805, states[40]= 0.004928
Saving checkpoint... 
Iteration: 1972183683, states[0] = -94.876526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984257802, states[0] = -94.998356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996350873, states[0] = -95.060339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008466983, states[0] = -95.086845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020548397, states[0] = 11.960079, states[40]= 0.005398
Saving checkpoint... 
Iteration: 2032689758, states[0] = -94.894208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044787248, states[0] = -95.024153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056914083, states[0] = -95.078051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068973738, states[0] = -95.087169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081072300, states[0] = 0.119512, states[40]= 0.004265
Saving checkpoint... 
Iteration: 2093179689, states[0] = -94.853265, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.965494
 - CaMKt in component CaMK (millimolar): 0.004950
 - cass in component intracellular_ions (millimolar): 0.000067
 - nai in component intracellular_ions (millimolar): 6.668942
 - nass in component intracellular_ions (millimolar): 6.668995
 - ki in component intracellular_ions (millimolar): 145.341869
 - kss in component intracellular_ions (millimolar): 145.341847
 - cansr in component intracellular_ions (millimolar): 1.176310
 - cajsr in component intracellular_ions (millimolar): 1.142100
 - cai in component intracellular_ions (millimolar): 0.000068
 - m in component INa (dimensionless): 0.003595
 - hf in component INa (dimensionless): 0.881101
 - hs in component INa (dimensionless): 0.881097
 - j in component INa (dimensionless): 0.881076
 - hsp in component INa (dimensionless): 0.727914
 - jp in component INa (dimensionless): 0.881062
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713507
 - hLp in component INaL (dimensionless): 0.459333
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.630505
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.705650
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935452
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001117
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342099
 - xs1 in component IKs (dimensionless): 0.233697
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997320
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:02:22 (956): called boinc_finish(0)

</stderr_txt>
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