𝕏

Task 54365720

Name HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1
Workunit 25812867
Created 22 Jun 2024, 23:17:19 UTC
Sent 23 Jun 2024, 0:47:24 UTC
Report deadline 26 Jun 2024, 10:23:24 UTC
Received 28 Jun 2024, 5:45:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230611
Run time 2 hours 21 min 54 sec
CPU time 1 hours 49 min 50 sec
Validate state Task was reported too late to validate
Credit 0.00
Device peak FLOPS 3.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.37 MB
Peak swap size 5.32 MB
Peak disk usage 0.36 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>
ile names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 279640221
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -21.807282 (After loading)
 - states[40]: 0.001147 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 279640221
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -21.807282 (After loading)
 - states[40]: 0.001147 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 279640221
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -21.807282 (After loading)
 - states[40]: 0.001147 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 298024115, states[0] = 25.024112, states[40]= 0.004138


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 298024115
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 25.024112 (After loading)
 - states[40]: 0.004138 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 298024115
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 25.024112 (After loading)
 - states[40]: 0.004138 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 298024115
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 25.024112 (After loading)
 - states[40]: 0.004138 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 314705133, states[0] = -94.274029, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 314705133
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.274029 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 314705133
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.274029 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 334221544, states[0] = -95.111961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354354498, states[0] = -95.300781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374819465, states[0] = -95.272669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392213516, states[0] = -95.028843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411893012, states[0] = -95.322246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429711981, states[0] = -94.984742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449674339, states[0] = -54.732031, states[40]= 0.000025
Saving checkpoint... 
Iteration: 468463599, states[0] = -95.345916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487394031, states[0] = -95.322626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506260465, states[0] = -95.195915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524668180, states[0] = -46.970478, states[40]= 0.000083
Saving checkpoint... 
Iteration: 545731735, states[0] = -95.140272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563763148, states[0] = -95.200379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581690952, states[0] = -78.965137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600339400, states[0] = -95.289577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620515250, states[0] = 23.522112, states[40]= 0.012337
Saving checkpoint... 
Iteration: 641004331, states[0] = 23.034381, states[40]= 0.212321
Saving checkpoint... 
Iteration: 658582024, states[0] = 12.206477, states[40]= 0.004175
Saving checkpoint... 
Iteration: 679336370, states[0] = -95.287091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696945226, states[0] = -95.340909, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 696945226
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.340909 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 696945226
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.340909 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 696945226
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.340909 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 706240971, states[0] = -95.159424, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 706240971
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.159424 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 721639035, states[0] = -20.894718, states[40]= 0.001148
Saving checkpoint... 
Iteration: 742125603, states[0] = -10.633967, states[40]= 0.001999


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 742125603
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -10.633967 (After loading)
 - states[40]: 0.001999 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 752474210, states[0] = -95.347971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763184783, states[0] = -69.084789, states[40]= 0.000002
Saving checkpoint... 
Iteration: 773582354, states[0] = 12.081140, states[40]= 0.004179
Saving checkpoint... 
Iteration: 784060470, states[0] = 19.263969, states[40]= 0.003687
Saving checkpoint... 
Iteration: 795354197, states[0] = -95.300064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808487954, states[0] = -95.350656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826931678, states[0] = -95.336694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844060683, states[0] = 19.205253, states[40]= 0.003694
Saving checkpoint... 
Iteration: 866136472, states[0] = -18.923556, states[40]= 0.001164


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 866136472
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -18.923556 (After loading)
 - states[40]: 0.001164 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 873648738, states[0] = -28.466513, states[40]= 0.000897
Saving checkpoint... 
Iteration: 882392670, states[0] = -95.321541, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 882392670
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.321541 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 892449640, states[0] = -95.341898, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 892449640
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.341898 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 911758728, states[0] = -95.192449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931386467, states[0] = -95.318524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950675274, states[0] = -55.958862, states[40]= 0.000021
Saving checkpoint... 
Iteration: 970220190, states[0] = -95.104862, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 970220190
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.104862 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 990706383, states[0] = -94.516924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010442614, states[0] = -95.339802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031176371, states[0] = -57.409222, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1054183376, states[0] = -67.028024, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1073263331, states[0] = -95.200089, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1073263331
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.200089 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1090314218, states[0] = -95.266713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108843642, states[0] = -95.292219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129067444, states[0] = 17.228089, states[40]= 0.003893
Saving checkpoint... 
Iteration: 1148825483, states[0] = -95.277317, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1148825483
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.277317 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1169806022, states[0] = -95.258055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189170389, states[0] = -49.670689, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1209195678, states[0] = -86.837133, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1209195678
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.837133 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1217240038, states[0] = -95.156946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226006428, states[0] = 20.622580, states[40]= 0.130940
Saving checkpoint... 
Iteration: 1233594653, states[0] = 7.032173, states[40]= 0.004232
Saving checkpoint... 
Iteration: 1242265230, states[0] = -95.203025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255148052, states[0] = -27.916856, states[40]= 0.000936
Saving checkpoint... 
Iteration: 1271556807, states[0] = 20.240393, states[40]= 0.003569
Saving checkpoint... 
Iteration: 1290313099, states[0] = -95.265352, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1290313099
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.265352 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1308791996, states[0] = -95.241477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328853510, states[0] = -95.298979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347029410, states[0] = 25.031209, states[40]= 0.003491
Saving checkpoint... 
Iteration: 1366768587, states[0] = -95.208284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382882896, states[0] = -95.316213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401001974, states[0] = 36.922573, states[40]= 0.156494
Saving checkpoint... 
Iteration: 1419070195, states[0] = 16.359867, states[40]= 0.003963
Saving checkpoint... 
Iteration: 1438795252, states[0] = -95.245347, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240623011704135995_ORdGradInc_k_23-Pueyo_APDR-conf_218_1_r411590877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 72.237354
     * GNaL_b in INaL: 0.020781
     * Gto_b in Ito: 0.138056
     * PCa_b in ICaL: 0.000078
     * GKr_b in IKr: 0.035765
     * GKs_b in IKs: 0.001567
     * GK1_b in IK1: 0.144101
     * Gncx_b in INaCa_i: 0.000919
     * Pnak_b in INaK: 84.486742
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.016911
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1438795252
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.245347 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1455645431, states[0] = -25.843249, states[40]= 0.001060
Saving checkpoint... 
Iteration: 1474863139, states[0] = -95.305031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494339430, states[0] = -95.288560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514043353, states[0] = -95.537549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531409567, states[0] = -95.494363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546622291, states[0] = -28.132941, states[40]= 0.000893
Saving checkpoint... 
Iteration: 1559993523, states[0] = -95.658044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578021589, states[0] = 23.233050, states[40]= 0.005707
Saving checkpoint... 
Iteration: 1596613045, states[0] = 22.256959, states[40]= 0.021581
Saving checkpoint... 
Iteration: 1613212455, states[0] = -20.363976, states[40]= 0.001203
Saving checkpoint... 
Iteration: 1630940293, states[0] = -47.204190, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1647380803, states[0] = 2.927410, states[40]= 0.004880
Saving checkpoint... 
Iteration: 1666695937, states[0] = -95.492960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684629897, states[0] = -35.748395, states[40]= 0.000419
Saving checkpoint... 
Iteration: 1700175150, states[0] = 5.841893, states[40]= 0.005019
Saving checkpoint... 
Iteration: 1717965297, states[0] = -85.926282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733631584, states[0] = -95.582758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743924729, states[0] = 22.984901, states[40]= 0.004839
Saving checkpoint... 
Iteration: 1753041551, states[0] = -48.876418, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1762851706, states[0] = 15.741718, states[40]= 0.004604
Saving checkpoint... 
Iteration: 1772448951, states[0] = 16.726421, states[40]= 0.004513
Saving checkpoint... 
Iteration: 1780207951, states[0] = 21.023251, states[40]= 0.085284
Saving checkpoint... 
Iteration: 1788955347, states[0] = 14.385948, states[40]= 0.004725
Saving checkpoint... 
Iteration: 1798817088, states[0] = 22.988297, states[40]= 0.009407
Saving checkpoint... 
Iteration: 1815471681, states[0] = -95.412133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833496692, states[0] = -95.388816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850756582, states[0] = -95.208482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867924703, states[0] = -95.345099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879034605, states[0] = 24.527810, states[40]= 0.003261
Saving checkpoint... 
Iteration: 1889619756, states[0] = -6.678280, states[40]= 0.002776
Saving checkpoint... 
Iteration: 1899675588, states[0] = -56.653952, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1912939261, states[0] = -95.340304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924812382, states[0] = -95.265522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937251967, states[0] = -95.180162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949759707, states[0] = -95.193534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962028359, states[0] = 25.064592, states[40]= 0.003568
Saving checkpoint... 
Iteration: 1974283943, states[0] = -95.230332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986117456, states[0] = -4.981256, states[40]= 0.003105
Saving checkpoint... 
Iteration: 1997154942, states[0] = -33.625741, states[40]= 0.000522
Saving checkpoint... 
Iteration: 2009376747, states[0] = -95.312185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021144836, states[0] = -25.380403, states[40]= 0.001081
Saving checkpoint... 
Iteration: 2032678994, states[0] = -60.928542, states[40]= 0.000009
Saving checkpoint... 
Iteration: 2043994417, states[0] = -95.350241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055668677, states[0] = -47.568527, states[40]= 0.000076
Saving checkpoint... 
Iteration: 2067293363, states[0] = -95.242123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079032053, states[0] = 24.862381, states[40]= 0.003353
Saving checkpoint... 
Iteration: 2090346227, states[0] = -95.292799, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.226977
 - CaMKt in component CaMK (millimolar): 0.008643
 - cass in component intracellular_ions (millimolar): 0.000077
 - nai in component intracellular_ions (millimolar): 6.316632
 - nass in component intracellular_ions (millimolar): 6.316704
 - ki in component intracellular_ions (millimolar): 145.640414
 - kss in component intracellular_ions (millimolar): 145.640386
 - cansr in component intracellular_ions (millimolar): 1.378694
 - cajsr in component intracellular_ions (millimolar): 1.333986
 - cai in component intracellular_ions (millimolar): 0.000078
 - m in component INa (dimensionless): 0.003502
 - hf in component INa (dimensionless): 0.885529
 - hs in component INa (dimensionless): 0.885522
 - j in component INa (dimensionless): 0.885482
 - hsp in component INa (dimensionless): 0.736321
 - jp in component INa (dimensionless): 0.885456
 - mL in component INaL (dimensionless): 0.000047
 - hL in component INaL (dimensionless): 0.707231
 - hLp in component INaL (dimensionless): 0.432036
 - a in component Ito (dimensionless): 0.000610
 - iF in component Ito (dimensionless): 0.999877
 - iS in component Ito (dimensionless): 0.580688
 - ap in component Ito (dimensionless): 0.000311
 - iFp in component Ito (dimensionless): 0.999877
 - iSp in component Ito (dimensionless): 0.649269
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.887835
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999673
 - jca in component ICaL (dimensionless): 0.999937
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001871
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.378394
 - xs1 in component IKs (dimensionless): 0.325803
 - xs2 in component IKs (dimensionless): 0.000085
 - xk1 in component IK1 (dimensionless): 0.997250
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:45:25 (15028): called boinc_finish(0)

</stderr_txt>
]]>