𝕏

Task 54298074

Name HuVeMOp_20240622140814813125_ORdGradInc_k_23-Pueyo_APDR-conf_553_0
Workunit 25780722
Created 22 Jun 2024, 12:12:00 UTC
Sent 22 Jun 2024, 15:10:41 UTC
Report deadline 26 Jun 2024, 0:46:41 UTC
Received 22 Jun 2024, 17:54:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241028
Run time 2 hours 30 min 56 sec
CPU time 2 hours 28 min 38 sec
Validate state Valid
Credit 57.34
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.06 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622140814813125_ORdGradInc_k_23-Pueyo_APDR-conf_553.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622140814813125_ORdGradInc_k_23-Pueyo_APDR-conf_553_0_r4815864_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240622140814813125_ORdGradInc_k_23-Pueyo_APDR-conf_553_0_r4815864_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 74.080077
     * GNaL_b in INaL: 0.014628
     * Gto_b in Ito: 0.091096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033131
     * GKs_b in IKs: 0.001648
     * GK1_b in IK1: 0.163192
     * Gncx_b in INaCa_i: 0.000994
     * Pnak_b in INaK: 75.091089
     * GKb_b in IKb: 0.004015
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024878
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14791359, states[0] = -95.448841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29831276, states[0] = -95.433297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44590643, states[0] = 2.757729, states[40]= 0.004271
Saving checkpoint... 
Iteration: 59226595, states[0] = -95.270719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73890896, states[0] = -95.417589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88466474, states[0] = -95.433141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103216868, states[0] = -95.234422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117949243, states[0] = -95.423960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132616608, states[0] = -12.206099, states[40]= 0.001769
Saving checkpoint... 
Iteration: 147285678, states[0] = -95.334621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161881171, states[0] = -95.399896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176390410, states[0] = -95.403243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191035932, states[0] = 22.577484, states[40]= 0.004554
Saving checkpoint... 
Iteration: 205662337, states[0] = -53.861991, states[40]= 0.000021
Saving checkpoint... 
Iteration: 220225988, states[0] = -95.246468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234676374, states[0] = -73.557262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 249094574, states[0] = 1.898289, states[40]= 0.004150
Saving checkpoint... 
Iteration: 263670949, states[0] = -65.166089, states[40]= 0.000003
Saving checkpoint... 
Iteration: 278622600, states[0] = -16.834832, states[40]= 0.001217
Saving checkpoint... 
Iteration: 293329908, states[0] = -95.371060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308009939, states[0] = 24.562800, states[40]= 0.048326
Saving checkpoint... 
Iteration: 322777291, states[0] = -95.323576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337395978, states[0] = -95.404567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352292196, states[0] = -95.339625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367360794, states[0] = -95.389298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382271817, states[0] = -95.316986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396981056, states[0] = -95.426113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411605885, states[0] = -4.432392, states[40]= 0.003262
Saving checkpoint... 
Iteration: 426254642, states[0] = -95.293937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440889403, states[0] = -95.402006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455734406, states[0] = -95.261427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470540119, states[0] = 21.537573, states[40]= 0.004411
Saving checkpoint... 
Iteration: 485135088, states[0] = -26.893154, states[40]= 0.000821
Saving checkpoint... 
Iteration: 499920256, states[0] = -95.412400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514755202, states[0] = -95.294686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529666526, states[0] = -59.161336, states[40]= 0.000009
Saving checkpoint... 
Iteration: 544493927, states[0] = -95.428040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559135391, states[0] = -27.141582, states[40]= 0.000807
Saving checkpoint... 
Iteration: 573724277, states[0] = -95.242797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588296504, states[0] = -95.343661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602958694, states[0] = -95.421801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617701327, states[0] = -95.155580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632481272, states[0] = -95.425977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647396886, states[0] = -95.404667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662192252, states[0] = -94.395346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676701588, states[0] = -95.159431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691259276, states[0] = -95.300345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705786900, states[0] = -95.333928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720390082, states[0] = -95.402066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734940543, states[0] = -95.417643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749478118, states[0] = -95.425357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763980423, states[0] = -95.425739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778342049, states[0] = -95.378543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792839361, states[0] = -95.376872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807283779, states[0] = -95.330511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821911180, states[0] = -95.409398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836850699, states[0] = -95.383559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851624774, states[0] = -18.578294, states[40]= 0.001111
Saving checkpoint... 
Iteration: 866231483, states[0] = -95.255931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880452999, states[0] = -95.420397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895221115, states[0] = -95.236450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909873738, states[0] = -95.395104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924576241, states[0] = 9.898301, states[40]= 0.004515
Saving checkpoint... 
Iteration: 939300086, states[0] = -95.346771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953923774, states[0] = -95.413082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968397639, states[0] = -95.404706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982836480, states[0] = -95.374906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997454107, states[0] = -95.420551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012119834, states[0] = -14.620705, states[40]= 0.001431
Saving checkpoint... 
Iteration: 1026666164, states[0] = -58.689791, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1041041420, states[0] = 21.193947, states[40]= 0.004386
Saving checkpoint... 
Iteration: 1055620217, states[0] = -14.925851, states[40]= 0.001396
Saving checkpoint... 
Iteration: 1070010305, states[0] = 24.579824, states[40]= 0.044126
Saving checkpoint... 
Iteration: 1084216574, states[0] = -95.227164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098378993, states[0] = -95.397276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112562760, states[0] = 14.751568, states[40]= 0.004490
Saving checkpoint... 
Iteration: 1126715609, states[0] = -95.225101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140964588, states[0] = -95.422592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155412508, states[0] = -95.409575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169659262, states[0] = -50.096856, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1183874322, states[0] = -95.395167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198173158, states[0] = -68.395030, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1212662551, states[0] = -54.102273, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1227405012, states[0] = -95.407086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242055385, states[0] = 17.132718, states[40]= 0.004414
Saving checkpoint... 
Iteration: 1256634580, states[0] = -26.477374, states[40]= 0.000843
Saving checkpoint... 
Iteration: 1271051454, states[0] = 18.334797, states[40]= 0.004373
Saving checkpoint... 
Iteration: 1285731238, states[0] = -95.255183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300075679, states[0] = 10.115425, states[40]= 0.004517
Saving checkpoint... 
Iteration: 1314482835, states[0] = -95.425742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329212012, states[0] = -95.216827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344066338, states[0] = 13.530459, states[40]= 0.004514
Saving checkpoint... 
Iteration: 1359038447, states[0] = 21.967258, states[40]= 0.004456
Saving checkpoint... 
Iteration: 1373793624, states[0] = -95.340294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388294565, states[0] = -95.341205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403224533, states[0] = -95.242678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417789058, states[0] = -95.335659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432508159, states[0] = 24.654507, states[40]= 0.075599
Saving checkpoint... 
Iteration: 1447181951, states[0] = -83.756307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461645628, states[0] = -35.896905, states[40]= 0.000308
Saving checkpoint... 
Iteration: 1476233238, states[0] = -95.258620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490993693, states[0] = -95.427318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505388775, states[0] = -95.629331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519883873, states[0] = -2.263920, states[40]= 0.004161
Saving checkpoint... 
Iteration: 1534264818, states[0] = 7.721904, states[40]= 0.005193
Saving checkpoint... 
Iteration: 1548831535, states[0] = -95.608434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563310177, states[0] = 24.688838, states[40]= 0.046253
Saving checkpoint... 
Iteration: 1577800993, states[0] = -17.764597, states[40]= 0.001276
Saving checkpoint... 
Iteration: 1592352097, states[0] = -95.650617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606503404, states[0] = 32.831272, states[40]= 0.149286
Saving checkpoint... 
Iteration: 1620654307, states[0] = 11.984600, states[40]= 0.005305
Saving checkpoint... 
Iteration: 1634803835, states[0] = -20.599234, states[40]= 0.001072
Saving checkpoint... 
Iteration: 1648906466, states[0] = -23.008968, states[40]= 0.000955
Saving checkpoint... 
Iteration: 1662977231, states[0] = 0.606635, states[40]= 0.004688
Saving checkpoint... 
Iteration: 1677102208, states[0] = -19.150112, states[40]= 0.001165
Saving checkpoint... 
Iteration: 1691379592, states[0] = -95.683984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705546493, states[0] = 15.244753, states[40]= 0.005341
Saving checkpoint... 
Iteration: 1719814607, states[0] = -95.595977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734056179, states[0] = 11.144012, states[40]= 0.005299
Saving checkpoint... 
Iteration: 1748257762, states[0] = -90.626245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762438099, states[0] = -95.635420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776521825, states[0] = -95.609223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790695489, states[0] = -95.697505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804742271, states[0] = -95.328749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818935148, states[0] = -95.459651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833123403, states[0] = -19.051292, states[40]= 0.001099
Saving checkpoint... 
Iteration: 1847295928, states[0] = -95.361055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861443446, states[0] = -95.429717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875698051, states[0] = -95.099076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889958298, states[0] = -95.425848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904033886, states[0] = 23.008107, states[40]= 0.004663
Saving checkpoint... 
Iteration: 1918140608, states[0] = -31.628492, states[40]= 0.000528
Saving checkpoint... 
Iteration: 1932341749, states[0] = -95.378860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946442448, states[0] = -95.418067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960620319, states[0] = -15.039329, states[40]= 0.001384
Saving checkpoint... 
Iteration: 1974874063, states[0] = -95.394784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989131163, states[0] = -23.721127, states[40]= 0.000959
Saving checkpoint... 
Iteration: 2003658661, states[0] = -49.398375, states[40]= 0.000043
Saving checkpoint... 
Iteration: 2018162006, states[0] = -53.436302, states[40]= 0.000023
Saving checkpoint... 
Iteration: 2032554052, states[0] = 17.544148, states[40]= 0.004399
Saving checkpoint... 
Iteration: 2046797467, states[0] = -95.343474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060979248, states[0] = -95.424542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075225484, states[0] = -95.243920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089773480, states[0] = -95.317690, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.303589
 - CaMKt in component CaMK (millimolar): 0.007530
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.388376
 - nass in component intracellular_ions (millimolar): 6.388445
 - ki in component intracellular_ions (millimolar): 145.586151
 - kss in component intracellular_ions (millimolar): 145.586126
 - cansr in component intracellular_ions (millimolar): 1.320614
 - cajsr in component intracellular_ions (millimolar): 1.278576
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003475
 - hf in component INa (dimensionless): 0.886798
 - hs in component INa (dimensionless): 0.886793
 - j in component INa (dimensionless): 0.886760
 - hsp in component INa (dimensionless): 0.738763
 - jp in component INa (dimensionless): 0.886738
 - mL in component INaL (dimensionless): 0.000046
 - hL in component INaL (dimensionless): 0.713131
 - hLp in component INaL (dimensionless): 0.443878
 - a in component Ito (dimensionless): 0.000607
 - iF in component Ito (dimensionless): 0.999878
 - iS in component Ito (dimensionless): 0.594181
 - ap in component Ito (dimensionless): 0.000309
 - iFp in component Ito (dimensionless): 0.999878
 - iSp in component Ito (dimensionless): 0.664534
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.903300
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999754
 - jca in component ICaL (dimensionless): 0.999954
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001645
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.363273
 - xs1 in component IKs (dimensionless): 0.300103
 - xs2 in component IKs (dimensionless): 0.000084
 - xk1 in component IK1 (dimensionless): 0.997229
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:54:16 (433435): called boinc_finish(0)

</stderr_txt>
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